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Critical Reviews in Toxicology Volume 44, 2014 - Issue 1
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Review Article

Dose–response approaches for nuclear receptor-mediated modes of action for liver carcinogenicity: Results of a workshop

Melvin E. AndersenThe Hamner Institutes for Health Sciences, Research Triangle Park NCUSACorrespondence[email protected]
,
R. Julian PrestonNHEERL, United States Environmental Protection Agency, Research Triangle Park NCUSA
,
Andrew MaierToxicology Excellence for Risk Assessment (TERA) Cincinnati, OHUSA
,
Alison M. WillisToxicology Excellence for Risk Assessment (TERA) Cincinnati, OHUSA
&
Jacqueline PattersonToxicology Excellence for Risk Assessment (TERA) Cincinnati, OHUSA
Pages 50-63 | Received 07 Jan 2013, Accepted 14 Aug 2013, Published online: 01 Oct 2013

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Katy O. Goyak, Satinder S. Sarang, A. Franzen, Susan J. Borghoff & Jessica P. Ryman-Rasmussen. (2022) Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats. Critical Reviews in Toxicology 52:5, pages 345-357.
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Tomoya Yamada, Brian G. Lake & Samuel M. Cohen. (2022) Evaluation of the human hazard of the liver and lung tumors in mice treated with permethrin based on mode of action. Critical Reviews in Toxicology 52:1, pages 1-31.
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Tomoya Yamada, Samuel M. Cohen & Brian G. Lake. (2021) Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Critical Reviews in Toxicology 51:5, pages 373-394.
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Brent D. Kerger, Kenneth T. Bogen, Anne E. Loccisano & James C. Lamb. (2018) Proposed reference dose for toxaphene carcinogenicity based on constitutive androstane receptor-mediated mode of action. Human and Ecological Risk Assessment: An International Journal 24:5, pages 1160-1180.
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Ted W. Simon, S. Stoney Simons$suffix/text()$suffix/text(), R. Julian Preston, Alan R. Boobis, Samuel M. Cohen, Nancy G. Doerrer, Penelope A. Fenner-Crisp, Tami S. McMullin, Charlene A. McQueen & J. Craig Rowlands. (2014) The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events. Critical Reviews in Toxicology 44:sup3, pages 17-43.
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Ellen T. Chang, Hans-Olov Adami, Paolo Boffetta, Philip Cole, Thomas B. Starr & Jack S. Mandel. (2014) A critical review of perfluorooctanoate and perfluorooctanesulfonate exposure and cancer risk in humans. Critical Reviews in Toxicology 44:sup1, pages 1-81.
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Articles from other publishers (10)

Tomoya Yamada. (2021) Application of humanized mice to toxicology studies: Evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Journal of Toxicologic Pathology 34:4, pages 283-297.
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Miwa Kondo, Kaori Miyata, Hirohisa Nagahori, Kayo Sumida, Thomas G Osimitz, Samuel M Cohen, Brian G Lake & Tomoya Yamada. (2019) Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse. Toxicological Sciences 168:2, pages 572-596.
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Louis Anthony (Tony) CoxJrJr. (2018) Biological mechanisms of non-linear dose-response for respirable mineral fibers. Toxicology and Applied Pharmacology 361, pages 137-144.
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Brian G. Lake. (2018) Human relevance of rodent liver tumour formation by constitutive androstane receptor (CAR) activators. Toxicology Research 7:4, pages 697-717.
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Richard C. Peffer, Matthew J. LeBaron, Michael Battalora, Werner H. Bomann, Christoph Werner, Manoj Aggarwal, Rocky R. Rowe & Helen Tinwell. (2018) Minimum datasets to establish a CAR-mediated mode of action for rodent liver tumors. Regulatory Toxicology and Pharmacology 96, pages 106-120.
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Louis Anthony Cox, Douglas A. Popken & Richard X. SunLouis Anthony Cox, Douglas A. Popken & Richard X. Sun. 2018. Causal Analytics for Applied Risk Analysis. Causal Analytics for Applied Risk Analysis 397 414 .
Ann E. Bradley, Joanna L. Shoenfelt & Judi L. Durda. (2016) Carcinogenicity and mode of action evaluation for alpha-hexachlorocyclohexane: Implications for human health risk assessment. Regulatory Toxicology and Pharmacology 76, pages 152-173.
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Rebecca A. Clewell, Patrick D. McMullen, Yeyejide Adeleye, Paul L. Carmichael & Melvin E. Andersen. 2016. Validation of Alternative Methods for Toxicity Testing. Validation of Alternative Methods for Toxicity Testing 205 230 .
Richard A. Becker, Grace Patlewicz, Ted W. Simon, J. Craig Rowlands & Robert A. Budinsky. (2015) The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor. Regulatory Toxicology and Pharmacology 73:1, pages 172-190.
Crossref
M.E. Andersen, S. Bhattacharya & W. Hanneman. 2014. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.

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