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Research Article

Design, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands

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Pages 341-349 | Received 04 May 2010, Accepted 19 Jul 2010, Published online: 27 Apr 2011

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Ramakrishna V. S. Nirogi, Thrinath Reddy Bandyala, Veena Reballi, Jagadishu Babu Konda, Anand V. Daulatabad & Mukkanti Khagga. (2015) Design, synthesis and pharmacological evaluation of indolylsulfonamide amines as potent and selective 5-HT6 receptor antagonists. Journal of Enzyme Inhibition and Medicinal Chemistry 30:1, pages 85-97.
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Yuxin Zhang, Bingbing Duan, Lingling Zhou, Xiangrui Song & Zengqiang Song. (2023) Metal-Free Oxidative Dearomatization–Alkoxylation/Acyloxylation of Indoles: Synthesis of 2-Monosubstituted Indolin-3-ones. Organic Letters 25:42, pages 7678-7682.
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Cui Zhao & Chuanjun Song. (2021) Studies on the ɑ-lithiation-in situ intramolecular nucleophilic addition reactions of 2-acyl-N-sulfonylpyrroles. Tetrahedron Letters 68, pages 152907.
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Ping Li, Zhiqiang Zhou, Fan Yang, Yao Xu & Xiaoxiang Zhang. (2021) Palladium-Catalyzed Synthesis of 1 H -Indol-3-yl Acrylates from 2-Alkynyl Arylazides and Acrylic Acids . Chinese Journal of Organic Chemistry 41:8, pages 3235.
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E. González-Zamora & A. Islas-Jácome. 2020. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering.
Jindong Zhu, Shuaishuai Fang, Kewen Sun, Chao Fang, Tao Lu & Ding Du. (2018) N -Heterocyclic Carbene-Catalyzed Formal Conjugate Hydroacylation: An Atom-Economic Synthesis of 1 H -Indol-3-yl Esters . The Journal of Organic Chemistry 83:17, pages 10430-10435.
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Michael N. Gandy, Lindsay T. Byrne & Keith A. Stubbs. (2015) A simple and robust preparation of N-acetylindoxyls: precursors for indigogenic substrates. Organic & Biomolecular Chemistry 13:3, pages 905-908.
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María Javier Ramírez. (2013) 5-HT6 receptors and Alzheimer's disease. Alzheimer's Research & Therapy 5:2.
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