Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 26, Issue 3 (2011)

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Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 26, Issue 3 (2011)

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Editorial

Editorial
Enzyme Inhibition and more− A Tribute to John Smith
Claudiu T. Supuran
Pages: 301-302
Published online: 27 Apr 2011
CitationforEnzyme Inhibition and more− A Tribute to John Smith | Full Text | PDF (636.6 KB)
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Review Article

Article
Kinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach
Franz Worek, Nadine Aurbek, Timo Wille, Peter Eyer & Horst Thiermann
Pages: 303-308
Published online: 31 Aug 2010
AbstractforKinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach | Full Text | References | PDF (900.9 KB)
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Research Article

Article
Urease activity and l-ascorbic acid
Barbara Krajewska & Małgorzata Brindell
Pages: 309-318
Published online: 09 Aug 2010
AbstractforUrease activity and l-ascorbic acid | Full Text | References | PDF (918.5 KB)
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Article
Use of Quantitative Structure–Activity Relationship (QSAR) and ADMET prediction studies as screening methods for design of benzyl urea derivatives for anti-cancer activity
Deepak Lokwani, Shashikant Bhandari, Radha Pujari, Padma Shastri, Ganesh shelke & Vidya Pawar
Pages: 319-331
Published online: 17 Sep 2010
AbstractforUse of Quantitative Structure–Activity Relationship (QSAR) and ADMET prediction studies as screening methods for design of benzyl urea derivatives for anti-cancer activity | Full Text | References | PDF (1,002.8 KB)
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Article
Synthesis and in vitro antimicrobial activity of novel N-(6-chlorobenzo[d]thiazol-2-yl) hydrazine carboxamide derivatives of benzothiazole class
Sadaf J. Gilani, Suroor A. Khan, Nadeem Siddiqui, Suraj P. Verma, Pooja Mullick & Ozair Alam
Pages: 332-340
Published online: 31 Aug 2010
AbstractforSynthesis and in vitro antimicrobial activity of novel N-(6-chlorobenzo[d]thiazol-2-yl) hydrazine carboxamide derivatives of benzothiazole class | Full Text | References | PDF (837.8 KB)
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Article
Design, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands
Ramakrishna V.S. Nirogia, Ramasastri Kambhampati, Anand V. Daulatabad, Parandhama Gudla, Mohammad Shaikh, Pramod Kumar Achanta, Anil K. Shinde & Pramod Kumar Dubey
Pages: 341-349
Published online: 27 Apr 2011
AbstractforDesign, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands | Full Text | References | PDF (822.4 KB)
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Original Article

Article
Hyperbolic mixed-type inhibition of acetylcholinesterase by tetracyclic thienopyrimidines
C. M. González Tanarro & M. Gütschow
Pages: 350-358
Published online: 31 Aug 2010
AbstractforHyperbolic mixed-type inhibition of acetylcholinesterase by tetracyclic thienopyrimidines | Full Text | References | PDF (887.9 KB)
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Article
Ternary copper(II) complexes of levofloxacin and phenanthroline derivatives: In-vitro antibacterial, DNA interactions, and SOD-like activity
M.N. Patel, Pradhuman Amrutsinh Parmar, Deepen Sureshbhai Gandhi & Vasudev R. Thakkar
Pages: 359-366
Published online: 27 Jan 2011
AbstractforTernary copper(II) complexes of levofloxacin and phenanthroline derivatives: In-vitro antibacterial, DNA interactions, and SOD-like activity | Full Text | References | PDF (783.7 KB) | Supplemental
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Article
Molecular modelling studies on d-annulated benzazepinones as VEGF-R2 kinase inhibitors using docking and 3D-QSAR
Ping Lan, Jun-Rong Sun, Wan-Na Chen, Ping-Hua Sun & Wei-Min Chen
Pages: 367-377
Published online: 17 Sep 2010
AbstractforMolecular modelling studies on d-annulated benzazepinones as VEGF-R2 kinase inhibitors using docking and 3D-QSAR | Full Text | References | PDF (1.1 MB)
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Article
Fluorescence, circular dichroism, NMR, and docking studies of the interaction of the alkaloid malbrancheamide with calmodulin
Mario Figueroa, Martín González-Andrade, Alejandro Sosa-Peinado, Abraham Madariaga-Mazón, Federico Del Río-Portilla, María Del Carmen González & Rachel Mata
Pages: 378-385
Published online: 13 Oct 2010
AbstractforFluorescence, circular dichroism, NMR, and docking studies of the interaction of the alkaloid malbrancheamide with calmodulin | Full Text | References | PDF (868.1 KB) | Supplemental
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Article
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors
Yuping Liu, Miaoqin She, Zhicong Wu & Renke Dai
Pages: 386-393
Published online: 13 Oct 2010
AbstractforThe inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors | Full Text | References | PDF (813.3 KB)
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Article
Transition metal complexes with N, S donor ligands as synthetic antioxidants: Synthesis, characterization and antioxidant activity
Alka Choudhary, Renu Sharma, Meena Nagar & Mohammed Mohsin
Pages: 394-403
Published online: 13 Oct 2010
AbstractforTransition metal complexes with N, S donor ligands as synthetic antioxidants: Synthesis, characterization and antioxidant activity | Full Text | References | PDF (798.1 KB)
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Article
Chemical composition and protective effect of oregano (Origanum heracleoticum L.) ethanolic extract on oxidative damage and on inhibition of NO in LPS-stimulated RAW 264.7 macrophages
Filomena Conforti, Mariangela Marrelli, Federica Menichini, Rosa Tundis, Giancarlo A. Statti, Umberto Solimene & Francesco Menichini
Pages: 404-411
Published online: 27 Apr 2011
AbstractforChemical composition and protective effect of oregano (Origanum heracleoticum L.) ethanolic extract on oxidative damage and on inhibition of NO in LPS-stimulated RAW 264.7 macrophages | Full Text | References | PDF (712.1 KB)
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Article
A QSAR study on 2-(4-methylpiperazin-1-yl)quinoxalines as human histamine H4 receptor ligands
Brij K. Sharma, Pradeep Pilania, Prithvi Singh & Yenamandra S. Prabhakar
Pages: 412-421
Published online: 13 Oct 2010
AbstractforA QSAR study on 2-(4-methylpiperazin-1-yl)quinoxalines as human histamine H4 receptor ligands | Full Text | References | PDF (832.5 KB)
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Article
Evaluation of 3-(4′-(4″-fluorophenyl)-6′-phenylpyrimidin-2′-yl)-2-phenylthiazolidin-4-one for in vivo modulation of biomarkers of chemoprevention in the 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis
J. Thanusu, V. Kanagarajan, S. Nagini & M. Gopalakrishnan
Pages: 422-429
Published online: 28 Oct 2010
AbstractforEvaluation of 3-(4′-(4″-fluorophenyl)-6′-phenylpyrimidin-2′-yl)-2-phenylthiazolidin-4-one for in vivo modulation of biomarkers of chemoprevention in the 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis | Full Text | References | PDF (646.1 KB)
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Article
Synthesis and antimicrobial studies of novel 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-one 4′-phenylthiosemicarbazones
Seeman Umamatheswari & Senthamaraikannan Kabilan
Pages: 430-439
Published online: 28 Oct 2010
AbstractforSynthesis and antimicrobial studies of novel 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-one 4′-phenylthiosemicarbazones | Full Text | References | PDF (777.2 KB)
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Short Communications

Honey, polen, and propolis extracts show potent inhibitory activity against the zinc metalloenzyme carbonic anhydrase
H. Sahin, R. Aliyazicioglu, O. Yildiz, S. Kolayli, A. Innocenti & C. T. Supuran
Pages: 440-444
Published online: 05 Aug 2010
AbstractforHoney, polen, and propolis extracts show potent inhibitory activity against the zinc metalloenzyme carbonic anhydrase | Full Text | References | PDF (575.4 KB)
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A FLT3-inhibitory constituent from the rhizomes of Anemarrhena asphodeloides
Sun-Young Han & Young-Won Chin
Pages: 445-448
Published online: 17 Sep 2010
AbstractforA FLT3-inhibitory constituent from the rhizomes of Anemarrhena asphodeloides | Full Text | References | PDF (607.9 KB)
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Synthesis and biological evaluation of polyhydroxy benzophenone as mushroom tyrosinase inhibitors
Jianlong Wu, Xuesen Hu & Lin Ma
Pages: 449-452
Published online: 13 Oct 2010
AbstractforSynthesis and biological evaluation of polyhydroxy benzophenone as mushroom tyrosinase inhibitors | Full Text | References | PDF (635.5 KB)
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