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Clinical Toxicology Volume 53, 2015 - Issue 6
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Methodology

Methodology for AACT evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning

Sophie GosselinDepartment of Emergency Medicine, Medical Toxicology Division, McGill University Health Centre, and Centre Antipoison du Québec, Québec, Québec, Canada
,
Martin MorrisSchulich Library of Science and Engineering,, McGill University, Montréal, Québec, Canada
,
Andrea Miller-NesbittSchulich Library of Science and Engineering,, McGill University, Montréal, Québec, Canada
,
Robert S. HoffmanDivision of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, New York University School of Medicine, New York, New York, USA
,
Bryan D. HayesDepartment of Pharmacy, University of Maryland Medical Center and Department of Emergency Medicine, University School of Medicine, Baltimore, Maryland, USA
,
Alexis F. TurgeonDivision of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, and CHU de Québec Research Center, Population Health and Optimal Health Practices Unit, Université Laval, Québec City, Québec, Canada
,
Brian M. GilfixDivision of Medical Biochemistry, Department of Medicine, McGill University Health Centre, Montreal, Québec, Canada
,
Ami M. GrunbaumDivision of Medical Biochemistry, Department of Medicine, McGill University Health Centre, Montreal, Québec, Canada
,
Theodore C. BaniaDepartment of Emergency Medicine, Mt Sinai Roosevelt, Mt Sinai St. Luke's, Icahn School of Medicine at Mt Sinai, New York, New York, USA
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Simon H. L. ThomasNational Poisons Information Service (Newcastle) and Medical Toxicology Centre, Institute of Cellular Medicine, Newcastle University, Newcastle, UK
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José A. MoraisDepartment of Medicine, Crabtree Nutrition Laboratories, McGill University Health Centre, McGill University, Montreal, Québec, Canada
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Andis GraudinsMonash Emergency Medicine and Clinical Toxicology, Monash Health and Southern Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia
,
Benoit BaileyDivision of Emergency Medicine, Department of Pediatrics, CHU Sainte-Justine, Montréal, QuébecCanada, Centre Antipoison du Québec, Québec, Canada
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Bruno MégarbaneDepartment of medical and toxicological intensive care, Lariboisière Hospital, Paris-Diderot University, Paris, France
,
Diane P. CalelloMedical Toxicology, Department of Emergency Medicine, Morristown Medical Center, Emergency Medical Associates, Morristown, New Jersey, USA
,
Michael LevineDepartment of Emergency Medicine, Section of Medical Toxicology, University of Southern California, Los Angeles, California, USA
,
Samuel J. StellpflugDepartment of Emergency Medicine, Regions Hospital, Saint Paul, Minnesota, USA
,
Lotte C. G. HoegbergDepartment of Anesthesiology, Danish Poisons Information Centre, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark
,
Ryan ChuangDivision of Clinical Pharmacology and Toxicology, Department of Emergency Medicine, University of Calgary, and Toxicology, Poison and Drug Information Service Alberta Health Services, Calgary, Alberta, Canada
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Christine StorkDepartment of Emergency Medicine, Upstate NY Poison Center and Upstate Medical University, Syacuse, New York, USA
,
Ashish BhallaDepartment of internal medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Carol J. RollinsBanner – University Medical Center Tuscon, University of Arizona College of Pharmacy, Tuscon, Arizona, USA
,
Valéry LavergneDepartment of Medical Biology, Sacré-Coeur Hospital, University of Montréal, Montréal, Québec, CanadaCorrespondence[email protected]
& on behalf of the AACT Lipid Emulsion Therapy workgroup show all
Pages 557-564 | Received 20 Jan 2015, Accepted 11 May 2015, Published online: 10 Jun 2015

Citations (19)

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Read on this site (8)

Michael E. Mullins & Donna L. Seger. (2020) Antidotal use of lipid emulsion – the pendulum swings. Clinical Toxicology 58:12, pages 1281-1283.
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Michael R. Fettiplace & Daniel J. McCabe. (2017) Lipid emulsion improves survival in animal models of local anesthetic toxicity: a meta-analysis. Clinical Toxicology 55:7, pages 617-623.
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Michael E. Mullins. (2016) Advancing the science of antidotal use of lipid emulsion. Clinical Toxicology 54:10, pages 897-898.
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Sophie Gosselin, Lotte C. G. Hoegberg, Robert. S. Hoffman, Andis Graudins, Christine M. Stork, Simon H. L. Thomas, Samuel J. Stellpflug, Bryan D. Hayes, Michael Levine, Martin Morris, Andrea Nesbitt-Miller, Alexis F. Turgeon, Benoit Bailey, Diane P. Calello, Ryan Chuang, Theodore C. Bania, Bruno Mégarbane, Ashish Bhalla & Valéry Lavergne. (2016) Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning. Clinical Toxicology 54:10, pages 899-923.
Read now
Bryan D. Hayes, Sophie Gosselin, Diane P. Calello, Nicholas Nacca, Carol J. Rollins, Daniel Abourbih, Martin Morris, Andrea Nesbitt-Miller, José A. Morais & Valéry Lavergne. (2016) Systematic review of clinical adverse events reported after acute intravenous lipid emulsion administration. Clinical Toxicology 54:5, pages 365-404.
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Michael Levine, Robert S. Hoffman, Valéry Lavergne, Christine M. Stork, Andis Graudins, Ryan Chuang, Samuel J. Stellpflug, Martin Morris, Andrea Miller-Nesbitt & Sophie Gosselin. (2016) Systematic review of the effect of intravenous lipid emulsion therapy for non-local anesthetics toxicity. Clinical Toxicology 54:3, pages 194-221.
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Lotte C. G. Hoegberg, Theodore C. Bania, Valéry Lavergne, Benoit Bailey, Alexis F. Turgeon, Simon H. L. Thomas, Martin Morris, Andrea Miller-Nesbitt, Bruno Mégarbane, Sheldon Magder & Sophie Gosselin. (2016) Systematic review of the effect of intravenous lipid emulsion therapy for local anesthetic toxicity. Clinical Toxicology 54:3, pages 167-193.
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Ami M. Grunbaum, Brian M. Gilfix, Robert S. Hoffman, Valéry Lavergne, Martin Morris, Andrea Miller-Nesbitt & Sophie Gosselin. (2016) Review of the effect of intravenous lipid emulsion on laboratory analyses. Clinical Toxicology 54:2, pages 92-102.
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Articles from other publishers (11)

Karim Jaffal, Lucie Chevillard & Bruno Mégarbane. (2023) Lipid Emulsion to Treat Acute Poisonings: Mechanisms of Action, Indications, and Controversies. Pharmaceutics 15:5, pages 1396.
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Samuel J. Stellpflug, Michael E. Bond, Keith D. Henry, Kristin M. Engebretsen & Nicole D. Zantek. (2020) Intravenous Fat Emulsion Does Not Significantly Alter Clotting Markers in Dabigatran-Treated Blood. Indian Journal of Hematology and Blood Transfusion 37:1, pages 101-107.
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Přemysl Mladěnka, Lenka Applová, Jiří Patočka, Vera Marisa Costa, Fernando Remiao, Jana Pourová, Aleš Mladěnka, Jana Karlíčková, Luděk Jahodář, Marie Vopršalová, Kurt J. Varner & Martin Štěrba. (2018) Comprehensive review of cardiovascular toxicity of drugs and related agents. Medicinal Research Reviews 38:4, pages 1332-1403.
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Shogo Tsujikawa, Tadashi Matsuura, Kotaro Hori, Takashi Mori, Miyuki KunoKiyonobu Nishikawa. (2018) Superior Efficacy of Lipid Emulsion Infusion Over Serum Alkalinization in Reversing Amitriptyline-Induced Cardiotoxicity in Guinea Pig. Anesthesia & Analgesia 126:4, pages 1159-1169.
Crossref
Martyn Harvey & Grant Cave. (2017) Lipid emulsion in local anesthetic toxicity. Current Opinion in Anaesthesiology 30:5, pages 632-638.
Crossref
K. Jaffal, L. Chevillard & B. Megarbane. (2017) Place des émulsions lipidiques intraveineuses en toxicologieLipid resuscitation in acute poisonning. Médecine Intensive Réanimation 26:5, pages 373-382.
Crossref
Sa'ed H. Zyoud, W. Stephen Waring, Samah W. Al-Jabi, Waleed M. Sweileh, Belal Rahhal & Rahmat Awang. (2016) Intravenous Lipid Emulsion as an Antidote for the Treatment of Acute Poisoning: A Bibliometric Analysis of Human and Animal Studies. Basic & Clinical Pharmacology & Toxicology 119:5, pages 512-519.
Crossref
P. H. Rosenberg. (2016) Current evidence is not in support of lipid rescue therapy in local anaesthetic systemic toxicity. Acta Anaesthesiologica Scandinavica 60:8, pages 1029-1032.
Crossref
Dmytro O. Kryshtal, Sheila Dawling, Donna Seger & Bjorn C. Knollmann. (2015) In Vitro Studies Indicate Intravenous Lipid Emulsion Acts as Lipid Sink in Verapamil Poisoning. Journal of Medical Toxicology 12:2, pages 165-171.
Crossref
Joshua C. Reynolds & Bryan S. Judge. (2015) Successful treatment of flecainide-induced cardiac arrest with extracorporeal membrane oxygenation in the ED. The American Journal of Emergency Medicine 33:10, pages 1542.e1-1542.e2.
Crossref
Michael R. Fettiplace & Guy Weinberg. (2015) Past, Present, and Future of Lipid Resuscitation Therapy. Journal of Parenteral and Enteral Nutrition 39:1_suppl, pages 72S-83S.
Crossref

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