Advanced search
Publication Cover
Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 41, 2013 - Issue 2
Submit an article Journal homepage
1,785
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Enhanced solubility and oral absorption of sirolimus using D-α-tocopheryl polyethylene glycol succinate micelles

Min-Soo KimDepartment of Pharmaceutical Engineering, Inje University, Gimhae, Gyeongnam, Republic of Korea
,
Jung-Soo KimCollege of Pharmacy, Chungnam National University, Daejeon, Republic of Korea
,
Won Kyung ChoCollege of Pharmacy, Chungnam National University, Daejeon, Republic of Korea;Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea
&
Sung-Joo HwangYonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea;College of Pharmacy, Yonsei University, Incheon, Republic of KoreaCorrespondence[email protected]
Pages 85-91 | Received 07 Sep 2012, Accepted 17 Oct 2012, Published online: 10 Jan 2013

Citations (22)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Omkara Swami Muddineti, Asmitha Vanaparthi, Sri Vishnu Kiran Rompicharla, Preeti Kumari, Balaram Ghosh & Swati Biswas. (2018) Cholesterol and vitamin E-conjugated PEGylated polymeric micelles for efficient delivery and enhanced anticancer activity of curcumin: evaluation in 2D monolayers and 3D spheroids. Artificial Cells, Nanomedicine, and Biotechnology 46:sup1, pages 773-786.
Read now
Azadeh Haeri, Mahraz Osouli, Fereshteh Bayat, Sonia Alavi & Simin Dadashzadeh. (2018) Nanomedicine approaches for sirolimus delivery: a review of pharmaceutical properties and preclinical studies. Artificial Cells, Nanomedicine, and Biotechnology 46:sup1, pages 1-14.
Read now
Hanan Al-Lawati, Hamidreza Montazeri Aliabadi, Behzad Sharif Makhmalzadeh & Afsaneh Lavasanifar. (2018) Nanomedicine for immunosuppressive therapy: achievements in pre-clinical and clinical research. Expert Opinion on Drug Delivery 15:4, pages 397-418.
Read now
Marc Fakhoury. (2016) Drug delivery approaches for the treatment of glioblastoma multiforme. Artificial Cells, Nanomedicine, and Biotechnology 44:6, pages 1365-1373.
Read now
Susana MN Simões, Ana R Figueiras, Francisco Veiga, Angel Concheiro & Carmen Alvarez-Lorenzo. (2015) Polymeric micelles for oral drug administration enabling locoregional and systemic treatments. Expert Opinion on Drug Delivery 12:2, pages 297-318.
Read now

Articles from other publishers (17)

Ömer Türkmen & Esra Baloğlu. (2022) Development and characterization of self-assembling sirolimus-loaded micelles as a sublingual delivery system. Journal of Drug Delivery Science and Technology 76, pages 103836.
Crossref
Guillaume Le Guyader, Bernard Do, Ivo B. Rietveld, Pascale Coric, Serge Bouaziz, Jean-Michel Guigner, Philippe-Henri Secretan, Karine Andrieux & Muriel Paul. (2022) Mixed Polymeric Micelles for Rapamycin Skin Delivery. Pharmaceutics 14:3, pages 569.
Crossref
Jun Wang, Fengmei Lv, Tao Sun, Shoujin Zhao, Haini Chen, Yu Liu & Zhepeng Liu. (2021) Sorafenib Nanomicelles Effectively Shrink Tumors by Vaginal Administration for Preoperative Chemotherapy of Cervical Cancer. Nanomaterials 11:12, pages 3271.
Crossref
Marcela Tavares Luiz, Leonardo Delello Di Filippo, Renata Carolina Alves, Victor Hugo Sousa Araújo, Jonatas Lobato Duarte, Juliana Maldonado Marchetti & Marlus Chorilli. (2021) The use of TPGS in drug delivery systems to overcome biological barriers. European Polymer Journal 142, pages 110129.
Crossref
Mohammad Javed Ansari. (2019) An overview of techniques for multifold enhancement in solubility of poorly soluble drugs. Current Issues in Pharmacy and Medical Sciences 32:4, pages 203-209.
Crossref
Parijat Kanaujia, Ponnammal Poovizhi, Wai Kiong Ng & Reginald B. H. Tan. (2019) Preparation, Characterization and Prevention of Auto-oxidation of Amorphous Sirolimus by Encapsulation in Polymeric Films Using Hot Melt Extrusion. Current Drug Delivery 16:7, pages 663-671.
Crossref
Amber Nagy & Nicholas L Robbins. (2019) The hurdles of nanotoxicity in transplant nanomedicine. Nanomedicine 14:20, pages 2749-2762.
Crossref
Mamunur Rashid, Mohd Yaseen Malik, Sandeep K. Singh, Swati Chaturvedi, Jiaur R Gayen & Muhammad Wahajuddin. (2019) Bioavailability Enhancement of Poorly Soluble Drugs: The Holy Grail in Pharma Industry. Current Pharmaceutical Design 25:9, pages 987-1020.
Crossref
Jiaxin Pi, Shuya Wang, Wen Li, Dereje Kebebe, Ying Zhang, Bing Zhang, Dongli Qi, Pan Guo, Nan Li & Zhidong Liu. (2019) A nano-cocrystal strategy to improve the dissolution rate and oral bioavailability of baicalein. Asian Journal of Pharmaceutical Sciences 14:2, pages 154-164.
Crossref
Boncheol Goo, Woo-Yong Sim, Eun-Sol Ha, Min-Soo Kim, Cheong-Weon Cho & Sung-Joo Hwang. (2018) Preparation of Spray-dried Emulsion of Sirolimus for Enhanced Oral Bioavailability. Bulletin of the Korean Chemical Society 39:10, pages 1215-1218.
Crossref
Florian Stumpf & Cornelia M. Keck. (2018) Tablets made from paper. International Journal of Pharmaceutics 548:2, pages 812-819.
Crossref
Dong Shik Kim, Han-Gon Choi & Sung Giu Jin. (2018) Influence of Hydroxypropylmethylcellulose and Sodium Lauryl Sulfate on the Solubility and Dissolution of Sirolimus in Solvent-evaporated Solid Dispersions. Bulletin of the Korean Chemical Society 39:6, pages 778-783.
Crossref
Raj Kumar Thapa, Han-Gon Choi, Jong Oh Kim & Chul Soon Yong. (2017) Analysis and optimization of drug solubility to improve pharmacokinetics. Journal of Pharmaceutical Investigation 47:2, pages 95-110.
Crossref
Eun-Sol Ha, In-hwan Baek & Min-Soo Kim. (2016) Preparation and Characterization of TPGS-Colloidal Silica Microparticles for Enhancement of Solubility and Oral Bioavailability of Lercanidipine Hydrochloride. Bulletin of the Korean Chemical Society 37:5, pages 660-666.
Crossref
Youngseok Cho, Eun-Sol Ha, In-Hwan Baek, Min-Soo Kim, Cheong-Weon Cho & Sung-Joo Hwang. (2015) Enhanced Supersaturation and Oral Absorption of Sirolimus Using an Amorphous Solid Dispersion Based on Eudragit® E. Molecules 20:6, pages 9496-9509.
Crossref
Eun-Sol Ha, Jinsu Ok, Jongmin Noh, Hee-Young Jeong, Gwang-Ho Choo, Young-Suk Jung, In-hwan Baek, Jeong-Soo Kim, Wonkyung Cho, Sung-Joo Hwang & Min-Soo Kim. (2015) Fabrication and evaluation of celecoxib microparticle surface modified by hydrophilic cellulose and surfactant. International Journal of Biological Macromolecules 72, pages 1473-1478.
Crossref
Ursula Thormann, Maria De Mieri, Markus Neuburger, Sheela Verjee, Peter Altmann, Matthias Hamburger & Georgios Imanidis. (2014) Mechanism of Chemical Degradation and Determination of Solubility by Kinetic Modeling of the Highly Unstable Sesquiterpene Lactone Nobilin in Different Media. Journal of Pharmaceutical Sciences 103:10, pages 3139-3152.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.