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Original Article

Tumor necrosis factor blocker dose escalation among biologic naïve rheumatoid arthritis patients in commercial managed-care plans in the 2 years following therapy initiation

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Pages 635-643 | Accepted 13 Feb 2012, Published online: 01 Mar 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Katsuhiko Takabayashi, Fumihiko Ando & Takahiro Suzuki. (2019) Comparing the effectiveness of biological disease-modifying antirheumatic drugs using real-world data. Modern Rheumatology 29:1, pages 87-97.
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Walid Fakhouri, Pedro Lopez-Romero, Silvia Antonelli, Serena Losi, Veronica Rogai, Stefano Buda, Diego Sangiorgi, Valentina Perrone & Luca Degli Esposti. (2018) Treatment patterns, health care resource utilization and costs of rheumatoid arthritis patients in Italy: findings from a retrospective administrative database analysis. Open Access Rheumatology: Research and Reviews 10, pages 103-111.
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Luca Degli Esposti, Ennio Giulio Favalli, Diego Sangiorgi, Roberta Di Turi, Giuseppina Farina, Marco Gambera & Roberto Ravasio. (2017) Persistence, switch rates, drug consumption and costs of biological treatment of rheumatoid arthritis: an observational study in Italy. ClinicoEconomics and Outcomes Research 9, pages 9-17.
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Ning Wu, Sharvari Bhurke, Neel Shah & David J Harrison. (2015) Application of a validated algorithm to estimate the effectiveness and cost of biologics for rheumatoid arthritis in the US pharmacy benefit manager context. ClinicoEconomics and Outcomes Research 7, pages 257-266.
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Vasilis Fragoulakis, Elli Vitsou, Ana Cristina Hernandez & Nikolaos Maniadakis. (2015) Economic evaluation of anti-TNF agents for patients with rheumatoid arthritis in Greece. ClinicoEconomics and Outcomes Research 7, pages 85-93.
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Diego Sangiorgi, Maurizio Benucci, Carmela Nappi, Valentina Perrone, Stefano Buda & Luca Degli Esposti. (2015) Drug usage analysis and health care resources consumption in naïve patients with rheumatoid arthritis. Biologics: Targets and Therapy 9, pages 119-127.
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Machaon Bonafede, Barbara H. Johnson, Nicole Princic, Neel Shah & David J. Harrison. (2015) Cost per patient-year in response using a claims-based algorithm for the 2 years following biologic initiation in patients with rheumatoid arthritis. Journal of Medical Economics 18:5, pages 376-389.
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Joaquín Borrás-Blasco & Andres Navarro Ruiz. (2015) Dose modification of anti-TNF in rheumatoid arthritis and estimated economical impact: a review of observational studies. Expert Review of Pharmacoeconomics & Outcomes Research 15:1, pages 71-79.
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Machaon Bonafede, George J Joseph, Neel Shah, Nicole Princic & David J Harrison. (2014) Cost of tumor necrosis factor blockers per patient with rheumatoid arthritis in a multistate Medicaid population. ClinicoEconomics and Outcomes Research 6, pages 381-388.
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Amie T. Joyce, Shravanthi R. Gandra, Kathleen M. Fox, Timothy W. Smith & Michael W. Pill. (2014) National and regional dose escalation and cost of tumor necrosis factor blocker therapy in biologic-naïve rheumatoid arthritis patients in US health plans. Journal of Medical Economics 17:1, pages 1-10.
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Machaon Bonafede, George J. Joseph, Nicole Princic & David J. Harrison. (2013) Annual acquisition and administration cost of biologic response modifiers per patient with rheumatoid arthritis, psoriasis, psoriatic arthritis, or ankylosing spondylitis. Journal of Medical Economics 16:9, pages 1120-1128.
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Maxine D. Fisher, Crystal Watson, Kathleen M. Fox, Yen-Wen Chen & Shravanthi R. Gandra. (2013) Dosing patterns of three tumor necrosis factor blockers among patients with rheumatoid arthritis in a large United States managed care population. Current Medical Research and Opinion 29:5, pages 561-568.
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Articles from other publishers (11)

Min-Young Lee, Ju-Young Shin, Sun-Young Park, Donguk Kim, Hoon-Suk Cha & Eui-Kyung Lee. (2018) Persistence of biologic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: An analysis of the South Korean National Health Insurance Database. Seminars in Arthritis and Rheumatism 47:4, pages 485-491.
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Anagha Nadkarni, Donna McMorrow, Chad Patel, Robert Fowler & David Smith. (2017) Incidence of dose escalation and impact on biologic costs among patients with rheumatoid arthritis treated with three intravenous agents. Journal of Comparative Effectiveness Research 6:8, pages 671-682.
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Jordana Schmier, Kristine Ogden, Nancy Nickman, Michael T. Halpern, Mary Cifaldi, Arijit Ganguli, Yanjun Bao & Vishvas Garg. (2017) Costs of Providing Infusion Therapy for Rheumatoid Arthritis in a Hospital-based Infusion Center Setting. Clinical Therapeutics 39:8, pages 1600-1617.
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Xuefeng Wang, Li Li, Jun Wang, Liyang Dong, Yang Shu, Yong Liang, Liang Shi, Chengcheng Xu, Yuepeng Zhou, Yi Wang, Deyu Chen & Chaoming Mao. (2017) Inhibition of cytokine response to TLR stimulation and alleviation of collagen-induced arthritis in mice by Schistosoma japonicum peptide SJMHE1 . Journal of Cellular and Molecular Medicine 21:3, pages 475-486.
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Paolo Faccendini, Enrica Cantillo, Caterina Fanizza & Maria Grazia Celeste. (2017) Analisi di Farmacoutilizzazione dei Trattamenti Biologici Nelle Malattie Infiammatorie Immunomediate Croniche: I Risultati di Uno Studio Osservazionale Retrospettivo Condotto in un Centro Ospedaliero del Centro Italia. Global & Regional Health Technology Assessment: Italian; Northern Europe and Spanish 4:1, pages grhta.5000271.
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James Harnett, Robert Gerber, David Gruben, Andrew S. KoenigConnie Chen. (2016) Evaluation of Real-World Experience with Tofacitinib Compared with Adalimumab, Etanercept, and Abatacept in RA Patients with 1 Previous Biologic DMARD: Data from a U.S. Administrative Claims Database. Journal of Managed Care & Specialty Pharmacy 22:12, pages 1457-1471.
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Tao Gu, Neel Shah, Gaurav Deshpande, Derek H. Tang & Debra F. Eisenberg. (2016) Comparing Biologic Cost Per Treated Patient Across Indications Among Adult US Managed Care Patients: A Retrospective Cohort Study. Drugs - Real World Outcomes 3:4, pages 369-381.
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James Harnett, Jeffrey R. Curtis, Robert Gerber, David Gruben & Andrew Koenig. (2016) Initial Experience With Tofacitinib in Clinical Practice: Treatment Patterns and Costs of Tofacitinib Administered as Monotherapy or in Combination With Conventional Synthetic DMARDs in 2 US Health Care Claims Databases. Clinical Therapeutics 38:6, pages 1451-1463.
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Rafael Ferriols-Lisart & Francisco Ferriols-Lisart. (2015) Dose modifications of anti-TNF drugs in rheumatoid arthritis patients under real-world settings: a systematic review. Rheumatology International 35:7, pages 1193-1210.
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Grant W. Cannon, Scott L. DuVall, Candace L. Haroldsen, Liron Caplan, Jeffrey R. Curtis, Kaleb Michaud, Ted R. Mikuls, Andreas Reimold, David H. Collier, David J. Harrison, George J. Joseph & Brian C. Sauer. (2014) Persistence and Dose Escalation of Tumor Necrosis Factor Inhibitors in US Veterans with Rheumatoid Arthritis. The Journal of Rheumatology 41:10, pages 1935-1943.
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Steven W. Blume, Kathleen M. Fox, George Joseph, Chien-Chia Chuang, Jessy Thomas & Shravanthi R. Gandra. (2013) Tumor Necrosis Factor-Blocker Dose Escalation in Rheumatoid Arthritis Patients in a Pharmacy Benefit Management Setting. Advances in Therapy 30:5, pages 517-527.
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