Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 37, 2007 - Issue 10-11: Special Issue: Modelling and Simulation Approaches to in vitro-in vivo Extrapolation of ADME Properties in Drug Development
Submit an article Journal homepage
1,600
Views
76
CrossRef citations to date
0
Altmetric
Research Article

On the anticipation of the human dose in first-in-man trials from preclinical and prior clinical information in early drug development

P. J. Lowe Novartis Pharmaceuticals A.G, Basle, Switzerland
,
Y. Hijazi Novartis Pharmaceuticals A.G, Basle, Switzerland
,
O. Luttringer Novartis Pharmaceuticals A.G, Basle, Switzerland
,
H. Yin Novartis Pharmaceuticals, Inc., East Hanover, NJ, USA
,
R. Sarangapani Novartis Pharmaceuticals, Inc., East Hanover, NJ, USA
&
D. Howard Novartis Pharmaceuticals, Inc., East Hanover, NJ, USA
Pages 1331-1354 | Received 27 Apr 2007, Accepted 03 Jul 2007, Published online: 22 Sep 2008

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.