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Generation and characterization of ABT-981, a dual variable domain immunoglobulin (DVD-IgTM) molecule that specifically and potently neutralizes both IL-1α and IL-1β
Susan E LacyAbbVie Bioresearch Center; Global Biologics; Worcester, MAUSACorrespondence[email protected]
, Chengbin WuShanghai CP Guojian Pharmaceutical Co., Ltd.; Shanghai, China
, Dominic J AmbrosiAbbVie Bioresearch Center; Global Biologics; Worcester, MAUSA
, Chung-Ming HsiehAbbVie Bioresearch Center; Global Biologics; Worcester, MAUSA
, Sahana BoseAbbVie Bioresearch Center; Global Biologics; Worcester, MAUSA
, Renee MillerAbbVie Bioresearch Center; Global Biologics; Worcester, MAUSA
, Donna M ConlonAbbVie Bioresearch Center; Immunology Pharmacology; Worcester, MAUSA
, Edit TarcsaAbbVie Bioresearch Center; DMPK-BA; Worcester, MAUSA
, Ravi ChariAbbVie Bioresearch Center; Drug Product Development; Worcester, MAUSA
, Tariq GhayurAbbVie Bioresearch Center; Global Biologics; Worcester, MAUSA
& Rajesh V KamathAbbVie Bioresearch Center; Foundational Immunology; Worcester, MAUSA
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Pages 605-619
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Received 11 Nov 2014, Accepted 01 Mar 2015, Published online: 01 May 2015
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