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Xenobiotica
the fate of foreign compounds in biological systems
Volume 42, 2012 - Issue 7
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Animal Pharmacokinetics and Metabolism

The utility of pharmacokinetic–pharmacodynamic modeling in the discovery and optimization of selective S1P1 agonists

Simon TaylorImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UKCorrespondence[email protected]
,
James R. J. GrayImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Robert WillisImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Nigel DeeksImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Andrea HaynesImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Colin CampbellImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Pam GaskinImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Karen LeavensImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Emmanuel DemontImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Simon DowellPlatform Technology & Science, GlaxoSmithKline, Stevenage, UK
,
Jenni CryanPlatform Technology & Science, GlaxoSmithKline, Stevenage, UK
,
Mary MorseImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
,
Aarti PatelMechanism & extrapolation Technologies, GlaxoSmithKline, Ware, UK
,
Helen GardenPlatform Technology & Science, GlaxoSmithKline, Harlow, UK
&
Jason WitheringtonImmuno-Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, Stevenage, UK
 show all
Pages 671-686 | Received 23 Sep 2011, Accepted 29 Nov 2011, Published online: 09 Jan 2012

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