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Xenobiotica
the fate of foreign compounds in biological systems
Volume 43, 2013 - Issue 2
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General Xenobiochemistry

Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips

Régis BaudoinLaboratoire de Biomécanique et Bio ingénierie, CNRS UMR 7338, Université de Technologie de Compiègne, France
,
Jean Matthieu ProtLaboratoire de Biomécanique et Bio ingénierie, CNRS UMR 7338, Université de Technologie de Compiègne, France
,
Grégory NicolasCEA, Service de Pharmacologie et d’Immunoanalyse, DSV/iBiTec-S, CEA/Saclay, Gif-Sur-Yvette Cedex, France
,
Jessy BrochetonPlate-Forme Génomique, Institut Cochin, 22 rue Méchain, Paris, France
,
Céline BrochotInstitut National de l’Environnement Industriel et des Risques (INERIS), Unité Modèles pour l’Ecotoxicologie et la Toxicologie (METO), Parc Alata BP2, Verneuil-en-Halatte, France
,
Cécile LegallaisLaboratoire de Biomécanique et Bio ingénierie, CNRS UMR 7338, Université de Technologie de Compiègne, France
,
Henri BenechCEA, Service de Pharmacologie et d’Immunoanalyse, DSV/iBiTec-S, CEA/Saclay, Gif-Sur-Yvette Cedex, France
&
Eric LeclercLaboratoire de Biomécanique et Bio ingénierie, CNRS UMR 7338, Université de Technologie de Compiègne, FranceCorrespondence[email protected]
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Pages 140-152 | Received 10 May 2012, Accepted 22 Jun 2012, Published online: 25 Jul 2012

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