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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 28, 2013 - Issue 5
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Research Article

1,2,4-thiadiazol-5(4H)-ones: a new class of selective inhibitors of Trypanosoma cruzi triosephosphate isomerase. Study of the mechanism of inhibition

Guzmán AlvarezGrupo de Química Medicinal, Laboratorio de Química Orgánica, Facultad de Ciencias-Facultad de Química, Universidad de la República, Uruguay
,
Beatriz Aguirre-LópezDepartamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico DF., Mexico
,
Nallely CabreraDepartamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico DF., Mexico
,
Eliã B. MarinsNúcleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Luzineide TinocoNúcleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Carlos Ignacio BatthyányUnidad de Bioquímica y Proteómica Analíticas, Instituto Pasteur de Montevideo, Montevideo, Uruguay
,
Marieta Tuena de Gómez-PuyouDepartamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico DF., Mexico
,
Armando Gómez PuyouDepartamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico DF., MexicoCorrespondence[email protected] [email protected] [email protected]; Mercedes [email protected]
,
Ruy Pérez-MontfortDepartamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico DF., MexicoCorrespondence[email protected] [email protected] [email protected]; Mercedes [email protected]
,
Hugo CerecettoGrupo de Química Medicinal, Laboratorio de Química Orgánica, Facultad de Ciencias-Facultad de Química, Universidad de la República, UruguayCorrespondence[email protected] [email protected] [email protected]; Mercedes [email protected]
&
Mercedes GonzálezGrupo de Química Medicinal, Laboratorio de Química Orgánica, Facultad de Ciencias-Facultad de Química, Universidad de la República, UruguayCorrespondence[email protected] [email protected] [email protected]; Mercedes [email protected]
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Pages 981-989 | Received 29 Apr 2012, Accepted 05 Jun 2012, Published online: 18 Jul 2012

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