Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 48, 2018 - Issue 4
142
Views
2
CrossRef citations to date
0
Altmetric
Animal Pharmacokinetics and Metabolism

Study on the pharmacokinetics of deoxyschizandrin and schizandrin in combination with epigallocatechin gallate, a component of green tea, in rats

, , , &
Pages 412-421 | Received 28 Feb 2017, Accepted 30 Apr 2017, Published online: 30 May 2017

References

  • Anderson CD, Wang J, Kumar GN, et al. (1995). Dexamethasone induction of taxol metabolism in the rat. Drug Metab Dispos 23:1286–90
  • Asha S, Vidyavathi M. (2010). Role of human liver microsomes in in vitro metabolism of drugs-a review. Appl Biochem Biotechnol 160:1699–722
  • Batt AL, Kostich MS, Lazorchak JM. (2008). Analysis of ecologically relevant pharmaceuticals in wastewater and surface water using selective solid-phase extraction and UPLC-MS/MS. Analyt Chem 80:5021–30
  • Cabrera C, Artacho R, Gimenez R. (2006). Beneficial effects of green tea–a review. J Am Coll Nutr 25:79–99
  • Cao YF, Zhang YY, Li J, et al. (2010). CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes. Xenobiotica 40:38–47
  • Del Rio D, Stewart AJ, Mullen W, et al. (2004). HPLC-MSn analysis of phenolic compounds and purine alkaloids in green and black tea. J Agric Food Chem 52:2807–15
  • Deng X, Chen X, Yin R, et al. (2008). Determination of deoxyschizandrin in rat plasma by LC-MS. J Pharm Biomed Anal 46:121–6
  • Fujita K. (2004). Food-drug interactions via human cytochrome P450 3A (CYP3A). Drug Metabol Drug Interact 20:195–217
  • Gao K, Sun J, Qiu F, et al. (2008). Uptake and transport of new antiasthmatic compounds by human intestinal Caco-2 cells: correlations with lipophilicity by biopartitioning chromatography. J Drug Deliv Sci Technol 18:231–7
  • Glaeser H, Bailey DG, Dresser GK, et al. (2007). Intestinal drug transporter expression and the impact of grapefruit juice in humans. Clin Pharm Ther 81:362–70
  • Graham HN. (1992). Green tea composition, consumption, and polyphenol chemistry. Prev Med 21:334–50
  • Guo YX, Han J, Zhang DY, et al. (2013). Aqueous two-phase system coupled with ultrasound for the extraction of lignans from seeds of Schisandra chinensis (turcz.) Baill. Ultrason Sonochem 20:125–32
  • Higdon JV, Frei B. (2003). Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit Rev Food Sci Nutr 43:89–143
  • Hu D, Cao Y, He R, et al. (2012a). Schizandrin, an antioxidant lignan from Schisandra chinensis, ameliorates Abeta1-42-induced memory impairment in mice. Oxid Med Cell Longev 2012:721721
  • Hu D, Li C, Han N, et al. (2012b). Deoxyschizandrin isolated from the fruits of Schisandra chinensis ameliorates Abeta(1)(-)(4)(2)-induced memory impairment in mice. Planta Med 78:1332–6
  • Hunter J, Hirst BH, Simmons NL. (1993). Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers. Pharm Res 10:743–9
  • Jodoin J, Demeule M, Beliveau R. (2002). Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim Biophys Acta 1542:149–59
  • Kamiloglu S, Capanoglu E, Grootaert C, Van Camp J. (2015). Anthocyanin absorption and metabolism by human intestinal Caco-2 cells-a review. Int J Mol Sci 16:21555–74
  • Kasprzyk-Hordern B, Dinsdale RM, Guwy AJ. (2007). Multi-residue method for the determination of basic/neutral pharmaceuticals and illicit drugs in surface water by solid-phase extraction and ultra performance liquid chromatography-positive electrospray ionisation tandem mass spectrometry. J Chromatogr A 1161:132–45
  • Konig J, Muller F, Fromm MF. (2013). Transporters and drug-drug interactions: important determinants of drug disposition and effects. Pharmacol Rev 65:944–66
  • Liu H, Zhang J, Li X, et al. (2012). Chemical analysis of twelve lignans in the fruit of Schisandra sphenanthera by HPLC-PAD-MS. Phytomedicine 19:1234–41
  • Lu Y, Chen DF. (2009). Analysis of Schisandra chinensis and Schisandra sphenanthera. J Chromatogr A 1216:1980–90
  • Maeda S, Sudo K, Miyamoto Y, et al. (1982). [Pharmacological studies on schizandra fruits. II. Effects of constituents of shizandra fruits on drugs induced hepatic damage in rats]. Yakugaku Zasshi 102:579–88
  • Mao S, Zhang H, Lv L, et al. (2011). Rapid determination and pharmacokinetics study of lignans in rat plasma after oral administration of Schisandra chinensis extract and pure deoxyschisandrin. Biomed Chromatogr 25:808–15
  • Meunier V, Bourrie M, Berger Y, Fabre G. (1995). The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications. Cell Biol Toxicol 11:187–94
  • Miller RJ, Jackson KG, Dadd T, et al. (2012). The impact of the catechol-O-methyltransferase genotype on vascular function and blood pressure after acute green tea ingestion. Mol Nutr Food Res 56:966–75
  • Muto S, Fujita K, Yamazaki Y, Kamataki T. (2001). Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450. Mutat Res 479:197–206
  • Niwa T, Kaneko H, Naritomi Y, et al. (1995). Species and sex differences of testosterone and nifedipine oxidation in liver microsomes of rat, dog and monkey. Xenobiotica 25:1041–9
  • Ono H, Matsuzaki Y, Wakui Y, et al. (1995). Determination of schizandrin in human plasma by gas chromatography-mass spectrometry. J Chromatogr B Biomed Appl 674:293–7
  • Opletal L, Sovova H, Bartlova M. (2004). Dibenzo[a,c]cyclooctadiene lignans of the genus Schisandra: importance, isolation and determination. J Chromatogr B Analyt Technol Biomed Life Sci 812:357–71
  • Paine MF, Oberlies NH. (2007). Clinical relevance of the small intestine as an organ of drug elimination: drug-fruit juice interactions. Expert Opin Drug Metab Toxicol 3:67–80
  • Potenza MA, Marasciulo FL, Tarquinio M, et al. (2007). EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR. Am J Physiol Endocrinol Metab 292:E1378–87
  • Qian F, Wei D, Zhang Q, Yang S. (2005). Modulation of P-glycoprotein function and reversal of multidrug resistance by (-)-epigallocatechin gallate in human cancer cells. Biomed Pharmacother 59:64–9
  • Sha X, Fang X. (2004). Transport characteristics of 9-nitrocamptothecin in the human intestinal cell line Caco-2 and everted gut sacs. Int J Pharm 272:161–71
  • Sugihara N, Kuroda N, Watanabe F, et al. (2017). Effects of catechins and their related compounds on cellular accumulation and efflux transport of mitoxantrone in Caco-2 cell monolayers. J Food Sci 82:1224–30
  • Tanaka Y, Taki Y, Sakane T, et al. (1995). Characterization of drug transport through tight-junctional pathway in Caco-2 monolayer: comparison with isolated rat jejunum and colon. Pharm Res 12:523–8
  • Toydemir G, Boyacioglu D, Capanoglu E, et al. (2013). Investigating the transport dynamics of anthocyanins from unprocessed fruit and processed fruit juice from sour cherry (Prunus cerasus L.) across intestinal epithelial cells. J Agric Food Chem 61:11434–41
  • Walgren RA, Walle UK, Walle T. (1998). Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells. Biochem Pharmacol 55:1721–7
  • Waxman DJ, Dannan GA, Guengerich FP. (1985). Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. Biochemistry 24:4409–17
  • Williamson G, Dionisi F, Renouf M. (2011). Flavanols from green tea and phenolic acids from coffee: critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages. Mol Nutr Food Res 55:864–73
  • Wu J, Cao Y, Zhang Y, et al. (2014). Deoxyschizandrin, a naturally occurring lignan, is a specific probe substrate of human cytochrome P450 3A. Drug Metabol Dispos 42:94–104
  • Xu H, Gan J, Liu X, et al. (2013). Gender-dependent pharmacokinetics of lignans in rats after single and multiple oral administration of Schisandra chinensis extract. J Ethnopharmacol 147:224–31
  • Xu M, Wang G, Xie H, et al. (2008). Pharmacokinetic comparisons of schizandrin after oral administration of schizandrin monomer, Fructus schisandrae aqueous extract and Sheng-Mai-San to rats. J Ethnopharmacol 115:483–8
  • Xu M, Wang G, Xie H, et al. (2005). Determination of schizandrin in rat plasma by high-performance liquid chromatography-mass spectrometry and its application in rat pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci 828:55–61
  • Yang CS, Landau JM. (2000). Effects of tea consumption on nutrition and health. J Nutr 130:2409–12
  • Yi W, Akoh CC, Fischer J, Krewer G. (2006). Absorption of anthocyanins from blueberry extracts by Caco-2 human intestinal cell monolayers. J Agric Food Chem 54:5651–8
  • Zeng Z, Shen ZL, Zhai S, et al. (2017). Transport of curcumin derivatives in Caco-2 cell monolayers. Eur J Pharm Biopharm. doi:10.1016/j.ejpb.2017.04.004
  • Zhao X, Liu C, Xu M, et al. (2016). Total lignans of Schisandra chinensis ameliorates Abeta1-42-induced neurodegeneration with cognitive impairment in mice and primary mouse neuronal cells. PLoS One 11:e0152772

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.