In vitro effects of peimine on the activity of cytochrome P450 enzymes

References

• Athukuri BL, Neerati P. (2016). Enhanced oral bioavailability of metoprolol with gallic acid and ellagic acid in male Wistar rats: involvement of CYP2D6 inhibition. Drug Metab Pers Ther 31:229–34.
   PubMedGoogle Scholar
• Basheer L, Kerem Z. (2015). Interactions between CYP3A4 and dietary polyphenols. Oxid Med Cell Longev 2015:854015.
   PubMed Web of Science ®Google Scholar
• Dehal S, Kupfer D. (1997). CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver. Cancer Res 57:3402–6.
   PubMed Web of Science ®Google Scholar
• de Albuquerque NCP, Carrão DB, Habenschus MD, de Oliveira ARM. (2018). Metabolism studies of chiral pesticides: a critical review. J Pharm Biomed Anal 147:89–109.
   PubMed Web of Science ®Google Scholar
• Jiang O, Zhou R, Wu D, et al. (2013). CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis. Tumour Biol 34:1215–24.
   PubMed Web of Science ®Google Scholar
• Jin Y, Wang Y, Miao J, et al. (2007). Cytochrome P450 3A5 genotype is associated with verapamil response in healthy subjects. Clin Pharmacol Ther 82:579–85.
   PubMed Web of Science ®Google Scholar
• Lamba J, Lin Y, Schuetz E, Thummel K. (2002). Genetic contribution to variable human CYP3A-mediated metabolism. Adv Drug Deliv Rev 54:1271–94.
   PubMed Web of Science ®Google Scholar
• Lang J, Li W, Zhao J, et al. (2017). Inhibitory effects of curculigoside on human liver cytochrome P450 enzymes. Xenobiotica 47:849–55.
   PubMed Web of Science ®Google Scholar
• Li H, Hung A, Li M, Yang A. (2019). Fritillariae thunbergii bulbus: traditional uses, phytochemistry, pharmacodynamics, pharmacokinetics and toxicity. Int J Mol Sci 20:1667–97.
   PubMed Web of Science ®Google Scholar
• Linhart K, Bartsch H, Seitz H K. (2014). The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts. Redox Biology 3:56–62.
   PubMed Web of Science ®Google Scholar
• Liu L, Sun S, Rui H, Li X. (2017). In vitro inhibitory effects of dihydromyricetin on human liver cytochrome P450 enzymes. Pharm Biol 55:1868–74.
   PubMed Web of Science ®Google Scholar
• Ma Y, Zhang Y, Zhai Y, et al. (2016). Development of a UPLC-TQ/MS approach for the determination of eleven bioactive components in Haizao Yuhu Decoction Plus-Minus Haizao and Gancao drug combination after oral administration in a rat model of hypothyroidism. Molecules 22:7.
   Web of Science ®Google Scholar
• Maksymchuk O, Shysh A, Rosohatska I, Chashchyn M. (2017). Quercetin prevents type 1 diabetic liver damage through inhibition of CYP2E1. Pharmacological Reports 69:1386–92.
   PubMed Web of Science ®Google Scholar
• Manikandan P, Nagini S. (2018). Cytochrome P450 structure, function and clinical significance: a review. Curr Drug Targets 19:38–54.
   PubMed Web of Science ®Google Scholar
• Martignoni M, Groothuis GM, de Kanter R. (2006). Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opin Drug Metab Toxicol 2:875–94.
   PubMed Web of Science ®Google Scholar
• Methaneethorn J, Chamnansua M, Kaewdang N, Lohitnavy M. (2014). A pharmacokinetic drug-drug interaction model of simvastatin and verapamil in humans. Conf Proc IEEE Eng Med Biol Soc 2014:5711–14.
   PubMedGoogle Scholar
• Mittal B, Tulsyan S, Kumar S, et al. (2015). Cytochrome P450 in cancer susceptibility and treatment. Adv Clin Chem 71:77–139.
   PubMed Web of Science ®Google Scholar
• Nishihara M, Yamasaki H, Czerniak R, Jenkins H. (2019). In vitro assessment of potential for CYP-inhibition-based drug-drug interaction between vonoprazan and clopidogrel. Eur J Drug Metab Pharmacokinet 44:217–27.
   PubMed Web of Science ®Google Scholar
• Pae HO, Oh H, Choi BM, et al. (2002). Differentiation-inducing effects of verticinone, an isosteroidal alkaloid isolated from the bulbus of Fritillaria ussuriensis, on human promyelocytic leukemia HL-60 cells. Biol Pharm Bull 25:1409–11.
   PubMed Web of Science ®Google Scholar
• Peterson B, Weyers M, Steenekamp JH, et al. (2019). Drug bioavailability enhancing agents of natural origin (bioenhancers) that modulate drug membrane permeation and pre-systemic metabolism. Pharmaceutics 11:33–78.
   PubMed Web of Science ®Google Scholar
• Qi XY, Liang SC, Ge GB, et al. (2013). Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes. Food Chem Toxicol 56:392–7.
   PubMed Web of Science ®Google Scholar
• Shi X, Zhang G, Mackie B, et al. (2016). Comparison of the in vitro metabolism of psoralidin among different species and characterization of its inhibitory effect against UDP- glucuronosyltransferase (UGT) or cytochrome p450 (CYP450) enzymes. Journal of Chromatography B 1029-1030:145–56.
   PubMed Web of Science ®Google Scholar
• Srinivas NR. (2016). Clinical drug-drug interactions of bosentan, a potent endothelial receptor antagonist, with various drugs: physiological role of enzymes and transporters. Gen Physiol Biophys 35:243–58.
   PubMed Web of Science ®Google Scholar
• Tseng E, Walsky RL, Luzietti RA, Jr, et al. (2014). Relative contributions of cytochrome CYP3A4 versus CYP3A5 for CYP3A-cleared drugs assessed in vitro using a CYP3A4-selective inactivator (CYP3cide). Drug Metab Dispos 42:1163–73.
   PubMed Web of Science ®Google Scholar
• Wang Z, Cao F, Chen Y, et al. (2018). Simultaneous determination and pharmacokinetics of peimine and peiminine in Beagle dog plasma by UPLC-MS/MS after the oral administration of Fritillariae ussuriensis Maxim and Fritillariae thunbergii Miq powder. Molecules 23:1573–86.
   Web of Science ®Google Scholar
• Wrighton S, Stevens J. (1992). The human hepatic cytochromes P450 involved in drug metabolism. Crit Rev Toxicol 22:1–21.
   PubMed Web of Science ®Google Scholar
• Xing H, Luo X, Li Y, et al. (2020). Effect of verapamil on the pharmacokinetics of hydroxycamptothecin and its potential mechanism. Pharm Biol 58:152–6.
   PubMed Web of Science ®Google Scholar
• Xiu L, Zhong G, Liu D, et al. (2017). Comparative efficacy and toxicity of different species of sargassum in Haizao Yuhu decoction in PTU-induced goiter rats. Evid Based Complement Alternat Med 2017:3526186.
   PubMedGoogle Scholar
• Xu J, Zhao W, Pan L, et al. (2016). Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular level. Fitoterapia 111:1–6.
   PubMed Web of Science ®Google Scholar
• Yan Z, Caldwell GW. (2001). Metabolism profiling, and cytochrome P450 inhibition & induction in drug discovery. Curr Topics Med Chem 1:403–25.
   PubMedGoogle Scholar
• Zhang Y, Li Y, Mao X, et al. (2016b). Thyroid hormone synthesis: a potential target of a Chinese herbal formula Haizao Yuhu Decoction acting on iodine-deficient goiter. Oncotarget 7:51699–712.
   PubMedGoogle Scholar
• Zhang JW, Liu Y, Cheng J, et al. (2007). Inhibition of human liver cytochrome P450 by star fruit juice. J Pharm Pharm Sci 10:496–503.
   PubMed Web of Science ®Google Scholar
• Zhang JX, Qi MJ, Shi MZ, Chen JJ, et al. (2019). Effects of Danhong injection, a traditional Chinese medicine, on nine cytochrome P450 isoforms in vitro. Biomed Chromatogr 33:e4454.
   PubMed Web of Science ®Google Scholar
• Zhang H, Ya G, Rui H. (2016a). Inhibitory effects of triptolide on human liver cytochrome P450 enzymes and P-glycoprotein. Eur J Drug Metab Pharmacokinet 42:89–98.
   Web of Science ®Google Scholar
• Zhao B, Shen C, Zheng Z, et al. (2018). Peiminine inhibits glioblastoma in vitro and in vivo through cell cycle arrest and autophagic flux blocking. Cell Physiol Biochem 51:1566–83.
   PubMedGoogle Scholar