Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Latest Articles
34
Views
0
CrossRef citations to date
0
Altmetric
Animal Pharmacokinetics and Metabolism

Developmental stage and infection status may affect drug distribution in the prostate of rats

, , , , , & show all
Received 27 Jan 2024, Accepted 12 Apr 2024, Published online: 25 Apr 2024

References

  • Brunckhorst O, Hashemi S, Martin A, George G, Hemelrijck MV, Dasgupta P, Stewart R, Ahmed K. 2021. Depression, anxiety, and suicidality in patients with prostate cancer: a systematic review and meta-analysis of observational studies. Prostate Cancer Prostatic Dis. 24(2):281–289. doi: 10.1038/s41391-020-00286-0.
  • Brunner M, Derendorf H, Müller M. 2005. Microdialysis for in vivo pharmacokinetic/pharmacodynamic characterization of anti-infective drugs. Curr Opin Pharmacol. 5(5):495–499. doi: 10.1016/j.coph.2005.04.010.
  • Chen L, Chen J, Mo F, Bian Z, Jin C, Chen X, Liang C. 2021. Genetic polymorphisms of IFNG, IFNGR1, and androgen receptor and chronic prostatitis/chronic pelvic pain syndrome in a Chinese Han population. Dis Markers. 2021:2898336. doi: 10.1155/2021/2898336.
  • Cheng FC, Tsai TR, Chen YF, Hung LC, Tsai TH. 2002. Pharmacokinetic study of levofloxacin in rat blood and bile by microdialysis and high-performance liquid chromatography. J Chromatogr A. 961(1):131–136. doi: 10.1016/s0021-9673(02)00506-x.
  • Cunha GR, Vezina CM, Isaacson D, Ricke WA, Timms BG, Cao M, Franco O, Baskin LS. 2018. Development of the human prostate. Differentiation. 103:24–45. doi: 10.1016/j.diff.2018.08.005.
  • da Fonseca AC, Matias D, Garcia C, Amaral R, Geraldo LH, Freitas C, Lima FR. 2014. The impact of microglial activation on blood-brain barrier in brain diseases. Front Cell Neurosci. 8:362. doi: 10.3389/fncel.2014.00362.
  • Dénes Á, Ferenczi S, Kovács KJ. 2011. Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood-brain barrier damage and brain oedema independently of infarct size. J Neuroinflammation. 8(1):164. doi: 10.1186/1742-2094-8-164.
  • Fares J, Kanojia D, Rashidi A, Ulasov I, Lesniak MS. 2020. Genes that mediate metastasis across the blood-brain barrier. Trends Cancer. 6(8):660–676. doi: 10.1016/j.trecan.2020.04.007.
  • Fulmer BR, Turner TT. 2000. A blood-prostate barrier restricts cell and molecular movement across the rat ventral prostate epithelium. J Urol. 163(5):1591–1594. doi: 0022-5347/00/1635-1591/0. doi: 10.1016/S0022-5347(05)67685-9.
  • Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S. 1998. Claudin-1 and-2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol. 141(7):1539–1550. doi: 10.1083/jcb.141.7.1539.
  • Gleave AM, Ci X, Lin D, Wang Y. 2020. A synopsis of prostate organoid methodologies, applications, and limitations. Prostate. 80(6):518–526. doi: 10.1002/pros.23966.
  • Gust J, Hay KA, Hanafi L-A, Li D, Myerson D, Gonzalez-Cuyar LF, Yeung C, Liles WC, Wurfel M, Lopez JA, et al. 2017. Endothelial activation and blood-brain barrier disruption in neurotoxicity after adoptive immunotherapy with CD19 CAR-T cells. Cancer Discov. 7(12):1404–1419. doi: 10.1158/2159-8290.CD-17-0698.
  • Gustafsson S, Eriksson J, Syvänen S, Eriksson O, Hammarlund-Udenaes M, Antoni G. 2017. Combined PET and microdialysis for in vivo estimation of drug blood-brain barrier transport and brain unbound concentrations. Neuroimage. 155:177–186. doi: 10.1016/j.neuroimage.2017.04.068.
  • Gustafsson S, Lindström V, Ingelsson M, Hammarlund-Udenaes M, Syvänen S. 2018. Intact blood-brain barrier transport of small molecular drugs in animal models of amyloid beta and alpha-synuclein pathology. Neuropharmacology. 128:482–491. doi: 10.1016/j.neuropharm.2017.08.002.
  • Han D, Fang W, Zhang R, Wei J, Kodithuwakku ND, Sha L, Ma W, Liu L, Li F, Li Y. 2016. Clematichinenoside protects blood brain barrier against ischemic stroke superimposed on systemic inflammatory challenges through up-regulating A20. Brain Behav Immun. 51:56–69. doi: 10.1016/j.bbi.2015.07.025.
  • Hitchcock SA. 2008. Blood–brain barrier permeability considerations for CNS-targeted compound library design. Curr Opin Chem Biol. 12(3):318–323. doi: 10.1016/j.cbpa.2008.03.019.
  • Hurtado FK, Weber B, Derendorf H, Hochhaus G, Dalla Costa T. 2014. Population pharmacokinetic modeling of the unbound levofloxacin concentrations in rat plasma and prostate tissue measured by microdialysis. Antimicrob Agents Chemother. 58(2):678–686. doi: 10.1128/AAC.01884-13.
  • Joseph DB, Turco AE, Vezina CM, Strand DW. 2021. Progenitors in prostate development and disease. Dev Biol. 473:50–58. doi: 10.1016/j.ydbio.2020.11.012.
  • Kind S, Büscheck F, Höflmayer D, Hube-Magg C, Kluth M, Tsourlakis MC, Steurer S, Clauditz TS, Luebke AM, Burandt E, et al. 2020. Claudin-1 upregulation is associated with favorable tumor features and a reduced risk for biochemical recurrence in ERG-positive prostate cancer. World J Urol. 38(9):2185–2196. doi: 10.1007/s00345-019-03017-w.
  • Klekner A, Ga’spa’r A, Kardos S, Szabó J, Cse’csei G. 2003. Cefazolin prophylaxis in neurosurgery monitored by capillary electrophoresis. J Neurosurg Anesthesiol. 15(3):249–254. doi: 10.1097/00008506-200307000-00013.
  • Liu Y, Yi S, Zhang J, Fang Z, Zhou F, Jia W, Liu Z, Ye G. 2013. Effect of microbubble-enhanced ultrasound on prostate permeability: a potential therapeutic method for prostate disease. Urology. 81(4):921.e1–7–921.e7. doi: 10.1016/j.urology.2012.12.022.
  • Liu D, Xu S, Xiao H, Wang Z, Mao N, Zhou J, Liu R, Huang Y. 2014. Quantitative determination of unbound levofloxacin by simultaneous microdialysis in rat pancreas after intravenous and oral doses. J Pharm Pharmacol. 66(9):1215–1221. doi: 10.1111/jphp.12252.
  • Malong L, Napoli I, Casal G, White IJ, Stierli S, Vaughan A, Cattin AL, Burden JJ, Hng KI, Bossio A, et al. 2023. Characterization of the structure and control of the blood-nerve barrier identifies avenues for therapeutic delivery. Dev Cell. 58(3):174–191.e8. doi: 10.1016/j.devcel.2023.01.002.
  • Marchand S, Frasca D, Dahyot-Fizelier C, Breheret C, Mimoz O, Couet W. 2008. Lung microdialysis study of levofloxacin in rats following intravenous infusion at steady state. Antimicrob Agents Chemother. 52(9):3074–3077. doi: 10.1128/AAC.00242-08.
  • Marchand S, Chauzy A, Dahyot-Fizelier C, Couet W. 2016. Microdialysis as a way to measure antibiotics concentration in tissues. Pharmacol Res. 111:201–207. doi: 10.1016/j.phrs.2016.06.001.
  • Marquez-Algaba E, Pigrau C, Bosch-Nicolau P, Viñado B, Serra-Pladevall J, Almirante B, Burgos J. 2021. Risk factors for relapse in acute bacterial prostatitis: the impact of antibiotic regimens. Microbiol Spectr. 9(2):e0053421. doi: 10.1128/Spectrum.00534-21.
  • Morais-Santos M, Werneck-Gomes H, Campolina-Silva GH, Santos LC, Mahecha GAB, Hess RA, Oliveira CA. 2018. Basal cells show increased expression of aromatase and estrogen receptor alpha in prostate epithelial lesions of male aging rats. Endocrinology. 159(2):723–732. doi: 10.1210/en.2017-00773.
  • Neelapu SS, Locke FL, Bartlett NL, Lekakis LJ, Miklos DB, Jacobson CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, et al. 2017. Axicabtagene ciloleucel CAR T-cell therapy in refractory large B-cell lymphoma. N Engl J Med. 377(26):2531–2544. doi: 10.1056/NEJMoa1707447.
  • Otani T, Furuse M. 2020. Tight junction structure and function revisited. Trends Cell Biol. 30(12):1014. doi: 10.1016/j.tcb.2020.10.001.
  • Palasik W, Fiszer U, Lechowicz W, Czartoryska B, Krzesiewicz M, Lugowska A. 2005. Assessment of relations between clinical outcome of ischemic stroke and activity of inflammatory processes in the acute phase based on examination of selected parameters. Eur Neurol. 53(4):188–193. doi: 10.1159/000086355.
  • Pea F, Pavan F, Nascimben E, Benetton C, Scotton PG, Vaglia A, Furlanut M. 2003. Levofloxacin disposition in cerebrospinal fluid in patients with external ventriculostomy. Antimicrob Agents Chemother. 47(10):3104–3108. doi: 10.1128/AAC.47.10.3104-3108.2003.
  • Perletti G, Wagenlehner FM, Naber KG, Magri V. 2009. Enhanced distribution of fourth-generation fluoroquinolones in prostatic tissue. Int J Antimicrob Agents. 33(3):206–210. doi: 10.1016/j.ijantimicag.2008.09.009.
  • Perletti G, Trinchieri A, Stamatiou K, Magri V. 2022. Safety considerations with new antibacterial approaches for chronic bacterial prostatitis. Expert Opin Drug Saf. 21(2):171–182. doi: 10.1080/14740338.2021.1956459.
  • Popescu TCT, Stepan AE, Florescu MM, Stepan MD, Simionescu CE. 2023. Immunoexpression of claudins-3, -4, and -7 in prostate adenocarcinomas. Rom J Morphol Embryol. 64(2):165–171. doi: 10.47162/RJME.64.2.06.
  • Raju P, Shashikanth N, Tsai PY, Pongkorpsakol P, Chanez-Paredes S, Steinhagen PR, Kuo WT, Singh G, Tsukita S, Turner JR. 2020. Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice. J Clin Invest. 130(10):5197–5208. doi: 10.1172/JCI138697.
  • Roehlen N, Muller M, Nehme Z, Crouchet E, Jühling F, Del Zompo F, Cherradi S, Duong FHT, Almeida N, Saviano A, et al. 2023. Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment. J Hepatol. 78(2):343–355. doi: 10.1016/j.jhep.2022.10.011.
  • Roudnicky F, Zhang JD, Kim BK, Pandya NJ, Lan Y, Sach-Peltason L, Ragelle H, Strassburger P, Gruener S, Lazendic M, et al. 2020. Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells. Proc Natl Acad Sci U S A. 117(33):19854–19865. doi: 10.1073/pnas.1911532117.
  • Schaeffer AJ, Nicolle LE. 2016. Urinary tract infections in older men. N Engl J Med. 374(6):562–571. doi: 10.1056/NEJMc1603508.
  • Shang Y, Cui D, Yi S. 2014. Opening tight junctions may be key to opening the blood-prostate barrier. Med Sci Monit. 20:2504–2507. doi: 10.12659/MSM.890902.
  • Shashikanth N, France MM, Xiao R, Haest X, Rizzo HE, Yeste J, Reiner J, Turner JR. 2022. Tight junction channel regulation by interclaudin interference. Nat Commun. 13(1):3780. doi: 10.1038/s41467-022-31587-8.
  • Siegel RL, Giaquinto AN, Jemal A. 2024. Cancer statistics, 2024. CA Cancer J Clin. 74(1):12–49. doi: 10.3322/caac.21820.
  • Sontheimer-Phelps A, Hassell BA, Ingber DE. 2019. Modelling cancer in microfluidic human organs-on-chips. Nat Rev Cancer. 19(2):65–81. doi: 10.1038/s41568-018-0104-6.
  • Spear LP, Brake SC. 1983. Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats. Dev Psychobiol. 16(2):83–109. doi: 10.1002/dev.420160203.
  • Spear L. 2000. Modeling adolescent development and alcohol use in animals. Alcohol Res Health. 24(2):115–123.
  • Spear LP. 2004. Adolescent brain development and animal models. Ann N Y Acad Sci. 1021(1):23–26. doi: 10.1196/annals.1308.002.
  • Swisshelm K, Machl A, Planitzer S, Robertson R, Kubbies M, Hosier S. 1999. SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily. Gene. 226(2):285–295. doi: 10.1016/s0378-1119(98)00553-8.
  • Vatine GD, Barrile R, Workman MJ, Sances S, Barriga BK, Rahnama M, Barthakur S, Kasendra M, Lucchesi C, Kerns J, et al. 2019. Human iPSC-derived blood-brain barrier chips enable disease modeling and personalized medicine applications. Cell Stem Cell. 24(6):995–1005.e6. doi: 10.1016/j.stem.2019.05.011.
  • Verbeeck RK. 2000. Blood microdialysis in pharmacokinetic and drug metabolism studies. Adv Drug Deliv Rev. 45(2-3):217–228. doi: 10.1016/s0169-409x(00)00110-1.
  • Wagenlehner FM, Pilatz A, Bschleipfer T, Diemer T, Linn T, Meinhardt A, Schagdarsurengin U, Dansranjavin T, Schuppe HC, Weidner W. 2013. Bacterial prostatitis. World J Urol. 31(4):711–716. doi: 10.1007/s00345-013-1055-x.
  • Wang X, Xue GX, Liu WC, Shu H, Wang M, Sun Y, Liu X, Sun YE, Liu CF, Liu J, et al. 2017. Melatonin alleviates lipopolysaccharide-compromised integrity of blood-brain barrier through activating AMP-activated protein kinase in old mice. Aging Cell. 16(2):414–421. doi: 10.1111/acel.12572.
  • Wei Y, Guan J, Ma X, Zhong Y, Ma J, Li F. 2015. Effect of glycyrrhizic acid on rhein renal penetration: a microdialysis study in rats. Xenobiotica. 45(12):1116–1121. doi: 10.3109/00498254.2015.1043660.
  • Xia H, Yang D, He W, Zhu X, Yan Y, Liu Z, Liu T, Yang J, Tan S, Jiang J, et al. 2021. Ultrasound-mediated microbubbles cavitation enhanced chemotherapy of advanced prostate cancer by increasing the permeability of blood-prostate barrier. Transl Oncol. 14(10):101177. doi: 10.1016/j.tranon.2021.101177.
  • Xie J, Bruggeman A, De Nolf C, Vandendriessche C, Van Imschoot G, Van Wonterghem E, Vereecke L, Vandenbroucke RE. 2023. Gut microbiota regulates blood-cerebrospinal fluid barrier function and Abeta pathology. Embo J. 42(17):e111515. doi: 10.15252/embj.2022111515.
  • Zhang S, Shi Y, Tang L, Wang J, Guo D, Wang M, Zhang X. 2018. Evaluation of brain targeting in rats of salvianolic acid B nasal delivery by the microdialysis technique. Xenobiotica. 48(8):851–859. doi: 10.1080/00498254.2017.1373207.
  • Zhu Y, Mo M, Wei Y, Wu J, Pan J, Freedland SJ, Zheng Y, Ye D. 2021. Epidemiology and genomics of prostate cancer in Asian men. Nat Rev Urol. 18(5):282–301. doi: 10.1038/s41585-021-00442-8.
  • Zhuang L, Xia HX, Gu Y, Hartmut D, Li Y, Liu CX. 2015. Theory and application of microdialysis in pharmacokinetic studies. Curr Drug Metab. 16(10):919–931. doi: 10.2174/1389200216666150812124109.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.