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Assessing Herbal Products with Health Claims

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REFERENCES

  • A-González, N. and Castrillo, A. (2011). Liver X receptors as regulators of macrophage inflammatory and metabolic pathways. Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1812(8):982–994.
  • Bakrim, A., Maria, A., Sayah, F., Lafont, R. and Takvorian, N. (2008). Ecdysteroids in spinach (Spinacia oleracea L.): Biosynthesis, transport and regulation of levels. Plant Physiol. Biochem. 46(10):844–54.
  • Bathori, M., Toth, N., Hunyadi, A., Marki, A. and Zador, E. (2008). Phytoecdysteroids and anabolic-androgenic steroids–structure and effects on humans. Curr. Med. Chem. 15(1):75–91.
  • Brandt, F. (2003). Pharmakokinetik und Metabolismus des 20-Hydroxyecdysons im Menschen, Taylor & Francis, Marburg (Germany).
  • Carmichael, N., Bausen, M., Boobis, A. R., Cohen, S. M., Embry, M., Fruijtier-Pölloth, C., Greim, H., Lewis, R., Meek, M. E., Mellor, H., Vickers, C. and Doe, J. (2011). Using mode of action information to improve regulatory decision-making: An ECETOC/ILSI RF/HESI workshop overview. Crit. Rev. Toxicol. 41(3):175–186.
  • Chen, Q., Xia, Y. and Qiu, Z. (2006). Effect of ecdysterone on glucose metabolism in vitro. Life Sci. 78 (10):1108–1113.
  • Cheng, D. M., Kutzler, L. W., Boler, D. D., Drnevich, J., Killefer, J. and Lila, M. A. (2012). Continuous infusion of 20-hydroxyecdysone increased mass of triceps brachii in C57BL/6 mice. Phytother. Res.:n/a–n/a.
  • Clark, A. R. and Belvisi, M. G. (2012). Maps and legends: The quest for dissociated ligands of the glucocorticoid receptor. Pharmacol. Ther. 134(1):54–67.
  • Cronin, M. T., Dearden, J. C., Walker, J. D. and Worth, A. P. (2003). Quantitative structure-activity relationships for human health effects: Commonalities with other endpoints. Environ. Toxicol. Chem. 22(8):1829–1843.
  • Destrez, B., Pinel, G., Monteau, F., Lafont, R. and Le Bizec, B. (2009). Detection and identification of 20-hydroxyecdysone metabolites in calf urine by liquid chromatography-high resolution or tandem mass spectrometry measurements and establishment of their kinetics of elimination after 20-hydroxyecdysone administration. Anal. Chim. Acta 637(1–2):178–184.
  • Dinan, L. (1995). A strategy for the identification of ecdysteroid receptor agonists and antagonists from plants. Eur. J. Entomol. 92:271–283.
  • Dinan, L. (2001). Phytoecdysteroids: Biological aspects. Phytochemistry 57:325–339.
  • Dinan, L. (2009). The karlson lecture. Phytoecdysteroids: What use are they? Arch. Insect. Biochem. Physiol. 72(3):126–141.
  • Dinan, L. and Lafont, R. (2006). Effects and applications of arthropod steroid hormones (ecdysteroids) in mammals. J. Endocrinol. 191:1–8.
  • EC, E. (1997). Regulation (EC) No 258/97 of the European parliament and of the council of 27 January 1997 concerning novel foods and novel food ingredients. Off. J. Eur. Union L 43/1.
  • EC, E. (2001). Directive 2001/83/EC of the European parliament and of the council of 6 November 2001 on the community code relating to medicinal products for human use. Off. J. Eur. Commun. L 311/67.
  • EC, E. (2002a). Directive 2002/46/EC of the European parliament and of the council of 10 June 2002 on the approximation of the laws of the member states relating to food supplements. Off. J. Eur. Commun. L 183/51.
  • EC, E. (2002b). Regulation (EC) No 178/2002 of the European parliament and of the council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European food safety authority and laying down procedures in matters of food safety. Off. J. Eur. Commun. L 31/1.
  • EC, E. (2004a). Directive 2004/24/EC of the European parliament and of the council of 31 March 2004 amending, as regards traditional herbal medicinal products, Directive 2001/83/EC on the community code relating to medicinal products for human use. Off. J. Eur. Unio. L 136/85.
  • EC, E. (2004b). Regulation (EC) No 882/2004 of the European parliament and of the council on official controls performed to ensure the verification of compliance with feed and food law, animal health and animal welfare rules. Off. J. Eur. Unio. L 165/1.
  • EC, E. (2006a). Commission directive 2006/37/EC of 30 march 2006 amending annex II to Directive 2002/46/EC of the European parliament and of the council as regards the inclusion of certain substances. Off. J. Eur. Unio. L 94/32.
  • EC, E. (2006b). Regulation (EC) No 1924/2006 of the European parliament and of the council of 20 December 2006 on nutrition and health claims made on foods. Off. J. Eur. Unio. L 404/9.
  • EC, E. (2009a). Commission regulation (EC) No 1170/2009 of 30 November 2009 amending Directive 2002/46/EC of the European parliament and of council and regulation (EC) No 1925/2006 of the European parliament and of the council as regards the lists of vitamin and minerals and their forms that can be added to foods, including food supplements. Off. J. Eur. Unio. L 314/36.
  • EC, E. (2009b). Directive 2009/39/EC of the European parliament and of the council of 6 May 2009 on foodstuffs intended for particular nutritional uses. Off. J. Eur. Union L 124/21.
  • EC, E. (2011). Commission regulation (EU) No 1161/2011 of 14 November 2011 amending Directive 2002/46/EC of the European parliament and of the council, regulation (EC) No 1925/2006 of the European parliament and of the council and commission regulation (EC) No 953/2009 as regards the lists of mineral substances that can be added to foods. Off. J. Eur. Unio. L 296/29.
  • FDA (2012). 2012 [cited 2012 2012]. Available from http://www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocuments/DietarySupplements/ucm257563.htm.
  • Foucault, A.-S., Mathe, V., Lafont, R., Even, P., Dioh, W., Veillet, S., Tome, D., Huneau, J.-F., Hermier, D. and Quignard-Boulange, A. (2012). Quinoa extract enriched in 20-hydroxyecdysone protects mice from diet-induced obesity and modulates adipokines expression. Obesity 20(2): 270-7.
  • Gorelick-Feldman, J. (2009). Phytoecdysteroids - Understanding Their Anabolic Activity. New Jersey.
  • Gorelick-Feldman, J., Cohick, W. and Raskin, I. (2010). Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells. Steroids 75(10):632–637.
  • Gorelick-Feldman, J., MacLean, D., Ilic, N., Poulev, A., Lila, M. A., Cheng, D. and Raskin, I. (2008). Phytoecdysteroids increase protein synthesis in skeletal muscle cells. J. Agric. Food Chem. 56(10):3532–3537.
  • Gulati, O. P. and Berry Ottaway, P. (2006). Legislation relating to nutraceuticals in the European union with a particular focus on botanical-sourced products. Toxicology 221(1):75–87.
  • Humphreys, G. (2012). New drugs from ancient texts. Bull. World Health Organ. 90:562–563.
  • Kizelsztein, P., Govorko, D., Komarnytsky, S., Evans, A., Wang, Z., Cefalu, W. T. and Raskin, I. (2009). 20-Hydroxyecdysone decreases weight and hyperglycemia in a diet-induced obesity mice model. Am. J. Physiol. Endocrinol. Metab. 296(3):E433–E439.
  • Kumpun, S., Girault, J. P., Dinan, L., Blais, C., Maria, A., Dauphin-Villemant, C., Yingyongnarongkul, B., Suksamrarn, A. and Lafont, R. (2011a). The metabolism of 20-hydroxyecdysone in mice: Relevance to pharmacological effects and gene switch applications of ecdysteroids. The J. Steroid Biochem. Mol. Biol. 126(1–2):1–9.
  • Kumpun, S., Maria, A., Crouzet, S., Evrard-Todeschi, N., Girault, J.-P. and Lafont, R. (2011b). Ecdysteroids from Chenopodium quinoa Willd., an ancient Andean crop of high nutritional value. Food Chem. 125(4):1226–1234.
  • Kutepova, T. A., Syrov, V. N., Khushbaktova, Z. A. and Saatov, Z. (2001). Hypoglycemic activity of the total ecdysteroid extract from Ajuga turkestanica. Pharm. Chem. J. 35(11):608–609.
  • Lafont, R. and Dinan, L. (2003). Practical uses for ecdysteroids in mammals including humans: An update. J. Insect Sci. 3:7.
  • Lafont, R., Harmatha, J., Marion-Poll, F., Dinan, L. N. and Wilson, I. D. Ecdybase - The Ecdysone Handbook. Université Pierre & Marie Curie, Paris 6, France; Institute of Organic Chemistry and Biochemistry, Taylor & Francis, Versailles, France. Available from: http://ecdybase.org.
  • Lafont, R. H., J.; Marion-Poll, F.; Dinan, L.; Wilson, I. D. (2012). The Ecdysone Handbook, 3rd ed. online 2012]. Available from http://ecdybase.org/. Accessed June 13, 2012.
  • Lapenna, S., Dinan, L., Friz, J., Hopfinger, A., Liu, J. and Hormann, R. E. (2009). Semi-synthetic ecdysteroids as gene-switch actuators: Synthesis, structure-activity relationships, and prospective ADME properties. Chem. Med. Chem. 4:55–68.
  • Lapenna, S., Friz, J., Barlow, A., Palli, R., Dinan, L. and Hormann, R. E. (2008). Ecdysteroid ligand-receptor selectivity: Exploring trends to design orthogonal gene switches. FEBS J. 275:5785–5809.
  • Lapenna, S., Fuart-Gatnik, M. and Worth, A. (2010). Review of QSAR Models and Software Tools for Predicting Acute and Chronic Systemic Toxicity. EUR 24639 EN. Taylor & Francis, Luxembourg.
  • Seidlova-Wuttke, D., Christel, D., Kapur, P., Nguyen, B. T., Jarry, H. and Wuttke, W. (2010). β-Ecdysone has bone protective but no estrogenic effects in ovariectomized rats. Phytomedicine 17(11):884–889.
  • Silano, V., Coppens, P., Larranaga-Guetaria, A., Minghetti, P. and Roth-Ehrang, R. (2011). Regulations applicable to plant food supplements and related products in the European union. Food Funct. 2(12):710–719.
  • Simon, P. and Koolman, J. (1989). Ecdysteroids in vertebrates: Pharmacological aspects. In: Ecdysone: From Chemistry to Mode of Action. pp. 254–259. Koolman, J., Ed., Taylor & Francis, Stuttgart.
  • Sláma, K. and Lafont, R. (1995). Insect hormones - ecdysteroids: Their presence and actions in vertebrates. The Eur. J. Entomol. 92:355–377.
  • Syrov, V. (2000). Comparative experimental investigation of the anabolic activity of phytoecdysteroids and steranabols. Pharm. Chem. J. 34(4):193–197.
  • Toth, N., Hunyadi, A., Bathori, M. and Zador, E. (2010). Phytoecdysteroids and vitamin D analogues - similarities in structure and mode of action. Curr. Med. Chem. 17(18):1974–1994.
  • Valerio, L. G., Jr., Arvidson, K. B., Chanderbhan, R. F. and Contrera, J. F. (2007). Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling. Toxicol. Appl. Pharm. 222(1):1–16.
  • Vedani, A., Dobler, M. and Smieško, M. (2012). VirtualToxLab — A platform for estimating the toxic potential of drugs, chemicals and natural products. Toxicol. Appl. Pharm. 261(2):142–153.
  • Vonk, J. A., Benigni, R., Hewitt, M., Nendza, M., Segner, H., van de Meent, D. and Cronin, M. T. (2009). The use of mechanisms and modes of toxic action in integrated testing strategies: The report and recommendations of a workshop held as part of the European union OSIRIS integrated project. Altern. Lab Anim. 37(5):557–571.
  • Wilborn, C., Taylor, L., Campbell, B., Kerksick, C., Rasmussen, C., Greenwood, M. and Kreider, R. (2006). Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males. J. Int. Soc. Sports Nutr. 3(2):19–27.
  • Worth, A. (2010). The role of QSAR methodology in the regulatory assessment of chemicals. Recent Advances in QSAR Studies: Methods and Applications. 367–382.
  • Worth, A., Fuart-Gatnik, M., Lapenna, S., Lo Piparo, E., Mostrag-Szlichtyng, A. and Serafimova, R. (2011). The use of Computational Methods in the Toxicological Assessment of Chemicals in Food: Current Status and Future Prospects. EUR 24748 EN. Taylor & Francis, Luxembourg.
  • Yao, T. P., Forman, B. M., Jiang, Z., Cherbas, L., Chen, J. D., McKeown, M., Cherbas, P. and Evans, R. M. (1993). Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature 366:476–479.

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