2,208
Views
6
CrossRef citations to date
0
Altmetric
RESEARCH ARTICLE

Preparation and evaluation of conjugate nanogels of glycyl-prednisolone with natural anionic polysaccharides as anti-arthritic delivery systems

, , &
Pages 136-144 | Received 13 Oct 2020, Accepted 14 Dec 2020, Published online: 29 Dec 2020

References

  • Abbasi M, Mousavi MJ, Jamalzehi S, et al. (2019). Strategies toward rheumatoid arthritis therapy; the old and the new. J Cell Physiol 234:10018–31.
  • Andreas K, Lübke C, Häupl T, et al. (2008). Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study. Arthritis Res Ther 10:R9.
  • Aono H, Sasano M. (2018). Animal models for rheumatoid arthritis. Clin Rheumatol Relat Res 30:28–37.
  • Ash Z, Emery P. (2012). The role of tocilizumab in the management of rheumatoid d arthritis. Expert Opin Biol Ther 12:1277–89.
  • Bae BC, Na K. (2010). Self-quenching polysaccharide-based nanogels of pullulan/folate-photosensitizer conjugates for photodynamic therapy. Biomaterials 31:6325–635.
  • Bax M, van Heemst J, Huizinga TW, et al. (2011). Genetics of rheumatoid arthritis: what have we learned? Immunogenetics 63:459–66.
  • Boers M, Verhoeven AC, Markusse HM, et al. (1997). Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis. Lancet 350:309–18.
  • Boridy S, Takahashi H, Akiyoshi K, Maysinger D. (2009). The binding of pullulan modified cholesteryl nanogels to Abeta oligomers and their suppression of cytotoxicity. Biomaterials 30:5583–91.
  • Buttgereit F, Doering G, Schaeffler A, et al. (2008). Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial. Lancet 371:205–14.
  • Buttgereit F, Mehta D, Kirwan J, et al. (2013). Low-dose prednisone chronotherapy for rheumatoid arthritis: a randomised clinical trial (CAPRA-2). Ann Rheum Dis 72:204–10.
  • Cabrales P, Tsai AG, Intaglietta M. (2005). Alginate plasma expander maintains perfusion and plasma viscosity during extreme hemodilution. Am J Physiol Heart Circ Physiol 288:H1708–H16.
  • Calabresi E, Petrelli F, Bonifacio AF, et al. (2018). One year in review 2018: pathogenesis of rheumatoid arthritis. Clin Exp Rheumatol 36:175–84.
  • Carter CT, Changolkar AK, McKenzie RS. (2012). Adalimumab, etanercept, and infliximab utilization patterns and drug costs among rheumatoid arthritis patients. J Med Econ 15:332–9.
  • Cassone G, Manfredi A, Vacchi C, et al. (2020). Treatment of rheumatoid arthritis-associated interstitial lung disease: lights and shadows. J Clin Med 9:1082.
  • Choy E. (2012). Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis. Rheumatology 51:v3–v11.
  • Cojocaru M, Chicoş B. (2013). Genetic differences between patients with rheumatoid arthritis. Rom J Intern Med 51:89–91.
  • Fraser JR, Laurent TC, Pertoft H, et al. (1981). Plasma clearance, tissue distribution and metabolism of hyaluronic acid injected intravenously in the rabbit. Biochem J 200:415–24.
  • Glant TT, Mikecz K, Rauch TA. (2014). Epigenetics in the pathogenesis of rheumatoid arthritis. BMC Med 12:35.
  • Goldie I, Nachemson A. (1969). Synovial pH in rheumatoid knee-joints. I. The effect of synovectomy. Acta Orthop Scand 40:634–41.
  • Hirakura T, Yasugi K, Nemoto T, et al. (2010). Hybrid hyaluronan hydrogel encapsulating nanogel as a protein nanocarrier: new system for sustained delivery of protein with a chaperone-like function. J Control Release 142:483–9.
  • Hirano S, Wakazono K, Agata N, et al. (1994). Effects of cytogenin, a novel anti-arthritic agent, on type II collagen-induced arthritis in DBA/1J mice and adjuvant arthritis in Lewis rats. Int J Tissue React 16:155–62.
  • Kim K, Choi H, Choi ES, et al. (2019). Hyaluronic acid-coated nanomedicine for targeted cancer therapy. Pharmaceutics 11:301.
  • Kong H, Lee Y, Hong S, et al. (2009). Sulfate-conjugated methylprednisolone as a colon-targeted methylprednisolone prodrug with improved therapeutic properties against rat colitis. J Drug Target 17:450–8.
  • Matsukuma H, Nakanishi H, Kawahara S, et al. (2005). Anti-inflammatory effect of moxibustion on adjuvant-induced arthritis. J Jpn Soc Balneol Climatol Phys Med 68:181–8.
  • Matsumura Y, Maeda H. (1986). A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 46:6387–92.
  • Metselaar JM, Wauben MH, Wagenaar-Hilbers JP, et al. (2003). Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes. Arthritis Rheum 48:2059–66.
  • Moscovici M. (2015). Present and future medical applications of microbial exopolysaccharides. Front Microbiol 6:1012.
  • Onishi H, Ikeuchi-Takahashi Y, Kawano K, et al. (2019). Preparation of chondroitin sulfate–glycyl-prednisolone conjugate nanogel and its efficacy in rats with ulcerative colitis. Biol Pharm Bull 42:1155–63.
  • Onishi H, Isoda Y, Matsuyama M. (2013). In vivo evaluation of chondroitin sulfate–glycyl-prednisolone for anti-arthritic effectiveness and pharmacokinetic characteristics. Int J Pharm 456:113–20.
  • Onishi H, Matsuyama M. (2013). Conjugate between chondroitin sulfate and prednisolone with a glycine linker: preparation and in vitro conversion analysis. Chem Pharm Bull (Tokyo) 61:902–12.
  • Onishi H, Oosegi T, Machida Y. (2008). Efficacy and toxicity of Eudragit-coated chitosan–succinyl-prednisolone conjugate microspheres using rats with 2,4,6-trinitrobenzenesulfonic acid-induced colitis. Int J Pharm 358:296–302.
  • Onishi H, Yoshida R, Matsuyama M. (2014). Chondroitin sulfate–glycyl-prednisolone conjugate as arthritis targeting system: localization and drug release in inflammatory joints. Biol Pharm Bull 37:1641–9.
  • Pandya NM, Dhalla NS, Santani DD. (2006). Angiogenesis—a new target for future therapy. Vascul Pharmacol 44:265–74.
  • Park K, Kim K, Kwon IC, et al. (2004). Preparation and characterization of self-assembled nanoparticles of heparin–deoxycholic acid conjugates. Langmuir 20:11726–31.
  • Quan LD, Yuan F, Liu XM, et al. (2010). Pharmacokinetic and biodistribution studies of N-(2-hydroxypropyl)methacrylamide copolymer–dexamethasone conjugates in adjuvant-induced arthritis rat model. Mol Pharm 7:1041–9.
  • Ren H, He Y, Liang J, et al. (2019). Role of liposome size, surface charge, and PEGylation on rheumatoid arthritis targeting therapy. ACS Appl Mater Interfaces 11:20304–15.
  • Severino P, da Silva CF, Andrade LN, et al. (2019). Alginate nanoparticles for drug delivery and targeting. Curr Pharm Des 25:1312–34.
  • Silva LC, Ortigosa LC, Benard G. (2010). Anti-TNF-α agents in the treatment of immune-mediated inflammatory diseases: mechanisms of action and pitfalls. Immunotherapy 2:817–33.
  • Taylor PC, Sivakumar B. (2005). Hypoxia and angiogenesis in rheumatoid arthritis. Curr Opin Rheumatol 17:293–8.
  • van den Hoven JM, Hofkens W, Wauben MH, et al. (2011). Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis. Int J Pharm 416:471–7.
  • Walz DT, DiMartino MJ, Misher A. (1971). Adjuvant-induced arthritis in rats. II. Drug effects on physiologic, biochemical and immunologic parameters. J Pharmacol Exp Ther 178:223–31.
  • Wang D, Miller SC, Liu XM, et al. (2007). Novel dexamethasone–HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis. Arthritis Res Ther 9:R2.
  • Ward JR, Cloud RS. (1966). Comparative effect of antirheumatic drugs on adjuvant-induced polyarthritis in rats. J Pharmacol Exp Ther 152:116–21.
  • Yamaoka K, Tanigawara Y, Nakagawa T, et al. (1981). A pharmacokinetic analysis program (multi) for microcomputer. J Pharmacobiodyn 4:879–85.
  • Yang M, Feng X, Ding J, et al. (2017). Nanotherapeutics relieve rheumatoid arthritis. J Control Release 252:108–24.
  • Yano H, Hirayama F, Kamada M, et al. (2002). Colon-specific delivery of prednisolone-appended alpha-cyclodextrin conjugate: alleviation of systemic side effect after oral administration. J Control Release 79:103–12.