iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment

References

• SchorrCA, ZanottiS, DellingerRP. Severe sepsis and septic shock: management and performance improvement. Virulence. 2014;5(1):190–199. doi:10.4161/viru.2740924335487
   PubMed Web of Science ®Google Scholar
• FerlitoM, WangQ, FultonWB, et al. Hydrogen sulfide [corrected] increases survival during sepsis: protective effect of CHOP inhibition. J Immunol. 2014;192(4):1806–1814. doi:10.4049/jimmunol.130083524403532
   PubMed Web of Science ®Google Scholar
• OsterburK, MannFA, KurokiK, DeClueA. Multiple organ dysfunction syndrome in humans and animals. J Vet Intern Med. 2014;28(4):1141–1151. doi:10.1111/jvim.1236424773159
   PubMed Web of Science ®Google Scholar
• TerryS, NieM, MatterK, BaldaMS. Rho signaling and tight junction functions. Physiology (Bethesda). 2010;25(1):16–26.20134025
   PubMed Web of Science ®Google Scholar
• GongZY, YuanZQ, DongZW, PengYZ. Glutamine with probiotics attenuates intestinal inflammation and oxidative stress in a rat burn injury model through altered iNOS gene aberrant methylation. Am J Transl Res. 2017;9(5):2535–2547.28560003
   PubMed Web of Science ®Google Scholar
• HuangCS, KawamuraT, ToyodaY, NakaoA. Recent advances in hydrogen research as a therapeutic medical gas. Free Radic Res. 2010;44(9):971–982. doi:10.3109/10715762.2010.50032820815764
   PubMed Web of Science ®Google Scholar
• LiuL, XieK, ChenH, et al. Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis. Brain Res. 2014;1589:78–92. doi:10.1016/j.brainres.2014.09.03025251596
   PubMed Web of Science ®Google Scholar
• YuY, YangY, BianY, et al. Hydrogen gas protects against intestinal injury in wild type but not NRF2 knockout mice with severe sepsis by regulating HO-1 and HMGB1 release. Shock. 2017;48(3):364–370. doi:10.1097/SHK.000000000000085628234792
   PubMed Web of Science ®Google Scholar
• YuY, YangY, YangM, WangC, XieK, YuY. Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway. Int Immunopharmacol. 2019;69:11–18. doi:10.1016/j.intimp.2019.01.02230660872
   PubMed Web of Science ®Google Scholar
• YangT, WangL, SunR, et al. Hydrogen-rich medium ameliorates lipopolysaccharide-induced barrier dysfunction via Rhoa-Mdia1 signaling in Caco-2 cells. Shock. 2016;45(2):228–237. doi:10.1097/SHK.000000000000050326529665
   PubMed Web of Science ®Google Scholar
• AggarwalS, YadavAK. Dissecting the iTRAQ data analysis. Methods Mol Biol. 2016;1362:277–291.26519184
   PubMedGoogle Scholar
• BianY, QinC, XinY, et al. Itraq-based quantitative proteomic analysis of lungs in murine polymicrobial sepsis with hydrogen gas treatment. Shock. 2018;49(2):187–195. doi:10.1097/SHK.000000000000092728632510
   PubMed Web of Science ®Google Scholar
• JinY, HofsethAB, CuiX, et al. American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells. Cancer Prev Res (Phila). 2010;3(3):339–347. doi:10.1158/1940-6207.CAPR-09-011620179294
   PubMed Web of Science ®Google Scholar
• YosephBP, KlingensmithNJ, LiangZ, et al. Mechanisms of intestinal barrier dysfunction in sepsis. Shock. 2016;46(1):52–59. doi:10.1097/SHK.000000000000056527299587
   PubMed Web of Science ®Google Scholar
• AngusDC, van der PollT. Severe sepsis and septic shock. N Engl J Med. 2013;369(9):840–851. doi:10.1056/NEJMra120862323984731
   PubMed Web of Science ®Google Scholar
• RhodesA, EvansLE, AlhazzaniW, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med. 2017;43(3):304–377.28101605
   PubMed Web of Science ®Google Scholar
• SalehAS. Early, goal-directed therapy for septic shock - a patient-level meta-analysis. N Engl J Med. 2017;377(10):994.28880501
   PubMed Web of Science ®Google Scholar
• BastaracheJA, MatthayMA. Cecal ligation model of sepsis in mice: new insights. Crit Care Med. 2013;41(1):356–357. doi:10.1097/CCM.0b013e318270e3ee23269150
   PubMed Web of Science ®Google Scholar
• OhsawaI, IshikawaM, TakahashiK, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med. 2007;13(6):688–694. doi:10.1038/nm157717486089
   PubMed Web of Science ®Google Scholar
• IchiharaM, SobueS, ItoM, ItoM, HirayamaM, OhnoK. Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles. Med Gas Res. 2015;5:12.26483953
   PubMed Web of Science ®Google Scholar
• KlingensmithNJ, CoopersmithCM. The gut as the motor of multiple organ dysfunction in critical illness. Crit Care Clin. 2016;32(2):203–212. doi:10.1016/j.ccc.2015.11.00427016162
   PubMed Web of Science ®Google Scholar
• IkedaM, ShimizuK, OguraH, et al. Hydrogen-rich saline regulates intestinal barrier dysfunction, dysbiosis, and bacterial translocation in a murine model of sepsis. Shock. 2018;50(6):640–647. doi:10.1097/SHK.000000000000109829293174
   PubMed Web of Science ®Google Scholar
• RittirschD, Huber-LangMS, FlierlMA, WardPA. Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc. 2009;4(1):31–36. doi:10.1038/nprot.2008.21419131954
   PubMed Web of Science ®Google Scholar
• BaumgartDC, DignassAU. Intestinal barrier function. Curr Opin Clin Nutr Metab Care. 2002;5(6):685–694. doi:10.1097/00075197-200211000-0001212394645
   PubMed Web of Science ®Google Scholar
• LevyMM, MaciasWL, VincentJL, et al. Early changes in organ function predict eventual survival in severe sepsis. Crit Care Med. 2005;33(10):2194–2201. doi:10.1097/01.CCM.0000182798.39709.8416215369
   PubMed Web of Science ®Google Scholar
• LiveraniE, RicoMC, YarathaL, TsygankovAY, KilpatrickLE, KunapuliSP. LPS-induced systemic inflammation is more severe in P2Y12 null mice. J Leukoc Biol. 2014;95(2):313–323. doi:10.1189/jlb.101251824142066
   PubMed Web of Science ®Google Scholar
• XieKL, LianNQ, KanYF, et al. iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice. Brain Res. 2020;1746:147003. doi:10.1016/j.brainres.2020.14700332603701
   PubMed Web of Science ®Google Scholar
• Conway-MorrisA, WilsonJ, Shankar-HariM. Immune activation in sepsis. Crit Care Clin. 2018;34(1):29–42. doi:10.1016/j.ccc.2017.08.00229149940
   PubMed Web of Science ®Google Scholar
• HotchkissRS, MonneretG, PayenD. Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy. Nat Rev Immunol. 2013;13(12):862–874. doi:10.1038/nri355224232462
   PubMed Web of Science ®Google Scholar
• HaakBW, WiersingaWJ. The role of the gut microbiota in sepsis. Lancet Gastroenterol Hepatol. 2017;2(2):135–143. doi:10.1016/S2468-1253(16)30119-428403983
   PubMed Web of Science ®Google Scholar
• LinX, ShiS, ShiS. Sepsis leads to thyroid impairment and dysfunction in rat model. Tissue Cell. 2016;48(5):511–515. doi:10.1016/j.tice.2016.07.00127521250
   PubMed Web of Science ®Google Scholar
• PowandaMC, WannemacherRW, CockerellGL. Nitrogen metabolism and protein synthesis during pneumococcal sepsis in rats. Infect Immun. 1972;6(3):266–271. doi:10.1128/IAI.6.3.266-271.19724404682
   PubMed Web of Science ®Google Scholar
• OrellanaRA, WilsonFA, GazzaneoMC, SuryawanA, DavisTA, NguyenHV. Sepsis and development impede muscle protein synthesis in neonatal pigs by different ribosomal mechanisms. Pediatr Res. 2011;69(6):473–478. doi:10.1203/PDR.0b013e3182176da121364490
   PubMed Web of Science ®Google Scholar
• DeLanoFA, HoytDB, Schmid-SchonbeinGW. Pancreatic digestive enzyme blockade in the intestine increases survival after experimental shock. Sci Transl Med. 2013;5(169):169ra111. doi:10.1126/scitranslmed.3005046
   Web of Science ®Google Scholar
• Schmid-SchonbeinGW, ChangM. The autodigestion hypothesis for shock and multi-organ failure. Ann Biomed Eng. 2014;42(2):405–414. doi:10.1007/s10439-013-0891-623989761
   PubMed Web of Science ®Google Scholar
• LiW, TaoS, WuQ, WuT, TaoR, FanJ. Glutamine reduces myocardial cell apoptosis in a rat model of sepsis by promoting expression of heat shock protein 90. J Surg Res. 2017;220:247–254. doi:10.1016/j.jss.2017.06.09029180187
   PubMed Web of Science ®Google Scholar
• BriassouliE, TzanoudakiM, GoukosD, et al. Glutamine may repress the weak LPS and enhance the strong heat shock induction of monocyte and lymphocyte HSP72 proteins but may not modulate the HSP72 mRNA in patients with sepsis or trauma. Biomed Res Int. 2015;2015:806042. doi:10.1155/2015/80604226550577
   PubMed Web of Science ®Google Scholar
• GaddnasF, KoskelaM, KoivukangasV, et al. Markers of collagen synthesis and degradation are increased in serum in severe sepsis: a longitudinal study of 44 patients. Crit Care. 2009;13(2):R53. doi:10.1186/cc778019358720
   PubMed Web of Science ®Google Scholar
• ShoganBD, BelogortsevaN, LuongPM, et al. Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak. Sci Transl Med. 2015;7(286):286ra268. doi:10.1126/scitranslmed.3010658
   Web of Science ®Google Scholar
• TingL, RadR, GygiSP, HaasW. MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics. Nat Methods. 2011;8(11):937–940. doi:10.1038/nmeth.171421963607
   PubMed Web of Science ®Google Scholar
• YuN, ZhangS, LuJ, et al. Serum amyloid A, an acute phase protein, stimulates proliferative and proinflammatory responses of keratinocytes. Cell Prolif. 2017;50(3):e12320. doi:10.1111/cpr.12320
   PubMed Web of Science ®Google Scholar
• TamamotoT, OhnoK, Goto-KoshinoY, FujinoY, TsujimotoH. Serum amyloid A uptake by feline peripheral macrophages. Vet Immunol Immunopathol. 2012;150(1–2):47–52. doi:10.1016/j.vetimm.2012.08.00522944261
   PubMed Web of Science ®Google Scholar
• ZhouH, ChenM, ZhangG, YeRD. Suppression of lipopolysaccharide-induced inflammatory response by fragments from serum amyloid A. J Immunol. 2017;199(3):1105–1112. doi:10.4049/jimmunol.170047028674180
   PubMed Web of Science ®Google Scholar
• YuMH, LiX, LiQ, et al. SAA1 increases NOX4/ROS production to promote LPS-induced inflammation in vascular smooth muscle cells through activating p38MAPK/NF-kappaB pathway. BMC Mol Cell Biol. 2019;20(1):15. doi:10.1186/s12860-019-0197-031216990
   PubMed Web of Science ®Google Scholar
• OkudaT, HigashiY, KokameK, TanakaC, KondohH, MiyataT. Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves. Mol Cell Biol. 2004;24(9):3949–3956. doi:10.1128/MCB.24.9.3949-3956.200415082788
   PubMed Web of Science ®Google Scholar
• HosoiF, IzumiH, KawaharaA, et al. N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of kappaB kinase beta expression. Cancer Res. 2009;69(12):4983–4991. doi:10.1158/0008-5472.CAN-08-488219491262
   PubMed Web of Science ®Google Scholar
• MurakamiY, WatariK, ShibataT, et al. N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1alpha by human gastric cancer cells. J Biol Chem. 2013;288(35):25025–25037. doi:10.1074/jbc.M113.47206823846687
   PubMed Web of Science ®Google Scholar
• MollenhauerJ, HolmskovU, WiemannS, et al. The genomic structure of the DMBT1 gene: evidence for a region with susceptibility to genomic instability. Oncogene. 1999;18(46):6233–6240. doi:10.1038/sj.onc.120307110597221
   PubMed Web of Science ®Google Scholar
• MollenhauerJ, HerbertzS, HelmkeB, et al. Deleted in malignant brain tumors 1 is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer. Cancer Res. 2001;61(24):8880–8886.11751412
   PubMed Web of Science ®Google Scholar
• RosenstielP, SinaC, EndC, et al. Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion. J Immunol. 2007;178(12):8203–8211. doi:10.4049/jimmunol.178.12.820317548659
   PubMed Web of Science ®Google Scholar
• UekiK, KondoT, KahnCR. Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms. Mol Cell Biol. 2004;24(12):5434–5446. doi:10.1128/MCB.24.12.5434-5446.200415169905
   PubMed Web of Science ®Google Scholar