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Original Research

Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling

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Pages 1463-1477 | Published online: 20 Feb 2015

References

  • GwinnMRVallyathanVNanoparticles: health effects – pros and consEnviron Health Perspect2006114121818182517185269
  • BakandSHayesADechsakulthornFNanoparticles: a review of particle toxicology following inhalation exposureInhal Toxicol201224212513522260506
  • GatooMANaseemSArfatMYDarAMQasimKZubairSPhysicochemical properties of nanomaterials: implication in associated toxic manifestationsBiomed Res Int2014201449842025165707
  • HansenSFMichelsonESKamperABorlingPStuer-LauridsenFBaunACategorization framework to aid exposure assessment of nanomaterials in consumer productsEcotoxicology200817543844718454314
  • YangYLiJLipid, protein and poly(NIPAM) coated mesoporous silica nanoparticles for biomedical applicationsAdv Colloid Interface Sci201420715516324268194
  • MaiWXMengHMesoporous silica nanoparticles: a multifunctional nano therapeutic systemIntegr Biol (Camb)201351192823042147
  • MalvindiMABrunettiVVecchioGGaleoneACingolaniRPompaPPSiO2 nanoparticles biocompatibility and their potential for gene delivery and silencingNanoscale20124248649522095171
  • LiangHJinCTangYWangFMaCYangYCytotoxicity of silica nanoparticles on HaCaT cellsJ Appl Toxicol201434436737224155225
  • LuXQianJZhouHIn vitro cytotoxicity and induction of apoptosis by silica nanoparticles in human HepG2 hepatoma cellsInt J Nanomedicine201161889190121931484
  • ZhuJLiaoLZhuLSize-dependent cellular uptake efficiency, mechanism, and cytotoxicity of silica nanoparticles toward HeLa cellsTalanta201310740841523598242
  • Fruijtier-PollothCThe toxicological mode of action and the safety of synthetic amorphous silica – a nanostructured materialToxicology20122942–3617922349641
  • ShannahanJHKodavantiUPBrownJMManufactured and airborne nanoparticle cardiopulmonary interactions: a review of mechanisms and the possible contribution of mast cellsInhal Toxicol201224532033922486349
  • NemmarAHolmeJARosasISchwarzePEAlfaro-MorenoERecent advances in particulate matter and nanoparticle toxicology: a review of the in vivo and in vitro studiesBiomed Res Int2013201327937123865044
  • ZhuMTWangBWangYEndothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: risk factors for early atherosclerosisToxicol Lett2011203216217121439359
  • BaiNKhazaeiMvan EedenSFLaherIThe pharmacology of particulate matter air pollution-induced cardiovascular dysfunctionPharmacol Ther20071131162916920197
  • AlbiniAMussiVParodiAInteractions of single-wall carbon nanotubes with endothelial cellsNanomedicine20106227728819699323
  • NapierskaDThomassenLCJRabolliVSize-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cellsSmall20095784685319288475
  • BauerATStrozykEAGorzelannyCCytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cellsBiomaterials201132338385839321840590
  • CorbalanJJMedinaCJacobyAMalinskiTRadomskiMWAmorphous silica nanoparticles trigger nitric oxide/peroxynitrite imbalance in human endothelial cells: inflammatory and cytotoxic effectsInt J Nanomedicine201162821283522131828
  • PetersKUngerREKirkpatrickCJGattiAMMonariEEffects of nano-scaled particles on endothelial cell function in vitro: studies on viability, proliferation and inflammationJ Mater Sci Mater Med200415432132515332593
  • DuanJCYuYBLiYToxic effect of silica nanoparticles on endothelial cells through DNA damage response via Chk1-dependent G2/M checkpointPlos One201384e6208723620807
  • LiYBZhangHXGuoCXCytotoxicity and DNA damage effect of TGA-capped CdTe quantum dotsChem Res Chin Univ2012282276281
  • TangLChengJNonporous silica nanoparticles for nanomedicine applicationNano Today20138329031223997809
  • LiuXSunJAEndothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-κB pathwaysBiomaterials201031328198820920727582
  • RampazzoEVoltanRPetrizzaLProper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosisNanoscale20135177897790523851463
  • HeQZhangZGaoYShiJLiYIntracellular localization and cytotoxicity of spherical mesoporous silica nano- and microparticlesSmall20095232722272919780070
  • SunLLiYLiuXMCytotoxicity and mitochondrial damage caused by silica nanoparticlesToxicol In Vitro20112581619162921723938
  • YuYDuanJLiYSilica nanoparticles induce autophagy and autophagic cell death in HepG2 cells triggered by reactive oxygen speciesJ Hazard Mater201427017618624583672
  • NishikawaTIwakiriNKanekoYNitric oxide release in human aortic endothelial cells mediated by delivery of amphiphilic polysiloxane nanoparticles to caveolaeBiomacromolecules20091082074208519583242
  • YangXLiuJHeHSiO2 nanoparticles induce cytotoxicity and protein expression alteration in HaCaT cellsPart Fibre Toxicol20107120180970
  • LiNXiaTNelAEThe role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticlesFree Radic Bio Med20084491689169918313407
  • SinghSShiTMDuffinREndocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO2: role of the specific surface area and of surface methylation of the particlesToxicol Appl Pharm20072222141151
  • LinWHuangYWZhouXDMaYIn vitro toxicity of silica nanoparticles in human lung cancer cellsToxicol Appl Pharmacol2006217325225917112558
  • ParkEJParkKOxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitroToxicol Lett20091841182519022359
  • NemmarABeegamSYuvarajuPYasinJShahinAAliBHInteraction of amorphous silica nanoparticles with erythrocytes in vitro: role of oxidative stressCell Physiol Biochem201434225526525033832
  • AlarifiSAliDAlakhtaniSAl SuhaibaniESAl-QahtaniAAReactive oxygen species-mediated DNA damage and apoptosis in human skin epidermal cells after exposure to nickel nanoparticlesBiol Trace Elem Res20141571849324307203
  • KrejsaCMFranklinCCWhiteCCLedbetterJASchievenGLKavanaghTJRapid activation of glutamate cysteine ligase following oxidative stressJ Biol Chem201028521161161612420332089
  • ThompsonSAWhiteCCKrejsaCMInduction of glutamate-cysteine ligase (γ-glutamylcysteine synthetase) in the brains of adult female mice subchronically exposed to methylmercuryToxicol Lett19991101–21910593589
  • WeldyCSWilkersonHWLarsonTVStewartJAKavanaghTJDIESEL particulate exposed macrophages alter endothelial cell expression of eNOS, iNOS, MCP1, and glutathione synthesis genesToxicol In Vitro20112582064207321920430
  • BonettiPOLermanLOLermanAEndothelial dysfunction: a marker of atherosclerotic riskArterioscler Thromb Vasc Biol200323216817512588755
  • DuránWNBreslinJWSánchezFAThe NO cascade, eNOS location, and microvascular permeabilityCardiovasc Res201087225426120462865
  • FelsJCalliesCKusche-VihrogKOberleithnerHNitric oxide release follows endothelial nanomechanics and not vice versaPflugers Arch2010460591592320809399
  • HukINanobashviliJNeumayerCL-arginine treatment alters the kinetics of nitric oxide and superoxide release and reduces ischemia/reperfusion injury in skeletal muscleCirculation19979626676759244241
  • KalinowskiLDobruckiITMalinskiTRace-specific differences in endothelial function – predisposition of African Americans to vascular diseasesCirculation2004109212511251715159296
  • CorbalanJJMedinaCJacobyAMalinskiTRadomskiMWAmorphous silica nanoparticles aggregate human platelets: potential implications for vascular homeostasisInt J Nanomedicine2012763163922334785
  • DuZZhaoDJingLCardiovascular toxicity of different sizes amorphous silica nanoparticles in rats after intratracheal instillationCardiovasc Toxicol201313319420723322373
  • SugawaraTChanPHReactive oxygen radicals and pathogenesis of neuronal death after cerebral ischemiaAntioxid Redox Sign200355597607
  • KubesPNitric oxide affects microvascular permeability in the intact and inflamed vasculatureMicrocirculation1995232352448748947
  • WhittleBJNitric oxide – a mediator of inflammation or mucosal defenceEur J Gastroenterol Hepatol1997911102610329431890
  • ZhenJLuHWangXQVaziriNDZhouXJUpregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen speciesAm J Hypertens2008211283418091741
  • ZhaoJXieYQianXJiangRSongWAcute effects of fine particles on cardiovascular system: differences between the spontaneously hypertensive rats and Wistar Kyoto ratsToxicol Lett20101931506020025942
  • PeretzASullivanJHLeottaDFDiesel exhaust inhalation elicits acute vasoconstriction in vivoEnviron Health Perspect2008116793794218629317
  • ThomsonEMKumarathasanPCalderón-GarcidueñasLVincentRAir pollution alters brain and pituitary endothelin-1 and inducible nitric oxide synthase gene expressionEnviron Res2007105222423317662977
  • WengYHKuoCYChiuYWKuoMLLiaoSLAlteration of nitric oxide gas on gene expression of endothelin-1 and endothelial nitric oxide synthase by a time- and dose-dependent manner in human endothelial cellsChin J Physiol2009522596419764340
  • KasperJHermannsMIBantzCInflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: xomparison with conventional monoculturesPart Fibre Toxicol201181621272353
  • YangLYanQQZhaoJThe role of potassium channel in silica nanoparticle-induced inflammatory effect in human vascular endothelial cells in vitroToxicol Lett20132231162424001805
  • MendozaATorres-HernandezJAAultJGPedersen-LaneJHGaoDLawrenceDASilica nanoparticles induce oxidative stress and inflammation of human peripheral blood mononuclear cellsCell Stress Chaperones201419677779024535706
  • EomHJChoiJOxidative stress of silica nanoparticles in human bronchial epithelial cell, Beas-2BToxicol In Vitro20092371326133219602432
  • KampfrathTMaiseyeuAYingZKChronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathwaysCirc Res2011108671672621273555
  • SunQHYuePBYingZKAir pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCKArterioscler Thromb Vasc Biol200828101760176618599801
  • GaoXBelmadaniSPicchiATumor necrosis factor-alpha induces endothelial dysfunction in Lepr(db) miceCirculation2007115224525417200442
  • BobryshevYVMonocyte recruitment and foam cell formation in atherosclerosisMicron200637320822216360317
  • LibbyPInflammation in atherosclerosisNature2002420691786887412490960
  • LiuXXueYDingTTSunJEnhancement of proinflammatory and procoagulant responses to silica particles by monocyte-endothelial cell interactionsPart Fibre Toxicol201293622985792
  • NapierskaDQuarckRThomassenLCAmorphous silica nanoparticles promote monocyte adhesion to human endothelial cells: size-dependent effectSmall20139343043823042701
  • GojovaAGuoBKotaRSRutledgeJCKennedyIMBarakatAIInduction of inflammation in vascular endothelial cells by metal oxide nanoparticles: effect of particle compositionEnviron Health Persp20071153403409
  • DeshmaneSLKremlevSAminiSSawayaBEMonocyte chemoattractant protein-1 (MCP-1): an overviewJ Interferon Cytokine Res200929631332619441883
  • ChoudhuryRPLeeJMGreavesDRMechanisms of disease: macrophage-derived foam cells emerging as therapeutic targets in atherosclerosisNat Clin Pract Cardiovasc Med20052630931516265535
  • MunteanuMCRaduMHermeneanAAntioxidative response induced by SiO2 nanoparticles in MRC5 cell lineRom Biotechnol Lett201015150005007
  • BeaFHudsonFNChaitAKavanaghTJRosenfeldMEInduction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elementsCirc Res200392438639312600891
  • BeaFHudsonFNNeff-LaFordHHomocysteine stimulates antioxidant response element-mediated expression of glutamate-cysteine ligase in mouse macrophagesAtherosclerosis2009203110511118691715
  • UngvariZBailey-DownsLGautamTAdaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemiaAm J Physiol Heart Circ Physiol20113004H1133H114021217061
  • LiuHEChangASTengCMChenCCTsaiACYangCRPotent anti-inflammatory effects of denbinobin mediated by dual inhibition of expression of inducible NO synthase and cyclooxygenase 2Shock201135219119720661183
  • EomHJChoiJOxidative stress of CeO2 nanoparticles via p38-Nrf-2 signaling pathway in human bronchial epithelial cell, Beas-2BToxicol Lett20091872778319429248
  • ZeYGZhengLZhaoXYMolecular mechanism of titanium dioxide nanoparticles-induced oxidative injury in the brain of miceChemosphere20139291183118923466083
  • WangJLiNZhengLP38-Nrf-2 signaling pathway of oxidative stress in mice caused by nanoparticulate TiO2Biol Trace Elem Res2011140218619720422311
  • SetyawatiMITayCYLeongDTEffect of zinc oxide nanomaterials-induced oxidative stress on the p53 pathwayBiomaterials20133438101331014224090840
  • HoeselBSchmidJAThe complexity of NF-κB signaling in inflammation and cancerMol Cancer2013128623915189