International Journal of Nanomedicine, Volume 10, Issue (2015)

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International Journal of Nanomedicine, Volume 10, Issue (2015)

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Original Research

Article
Renal interstitial fibrosis induced by high-dose mesoporous silica nanoparticles via the NF-κB signaling pathway
Xi Chen, Wang Zhouhua, Zhou Jie, Fu Xinlu, Liang Jinqiang, Qiu Yuwen & Huang Zhiying
Pages: 1-22
Published online: 18 Dec 2014
AbstractforRenal interstitial fibrosis induced by high-dose mesoporous silica nanoparticles via the NF-κB signaling pathway | Full Text | References | PDF (12.6 MB)
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Open Access
Article
Essential components of a successful doctoral program in nanomedicine
Anne L van de Ven, Mary H Shann & Srinivas Sridhar
Pages: 23-30
Published online: 19 Dec 2014
AbstractforEssential components of a successful doctoral program in nanomedicine | Full Text | References | PDF (363.3 KB)
  • 85 Views
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Open Access
Article
Potential anticancer properties of bioactive compounds of Gymnema sylvestre and its biofunctionalized silver nanoparticles
Kantha Deivi Arunachalam, Lilly Baptista Arun, Sathesh Kumar Annamalai & Aarrthy M Arunachalam
Pages: 31-41
Published online: 16 Dec 2014
AbstractforPotential anticancer properties of bioactive compounds of Gymnema sylvestre and its biofunctionalized silver nanoparticles | Full Text | References | PDF (1.7 MB)
  • 466 Views
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Open Access
Article
Activation of Schwann cells in vitro by magnetic nanocomposites via applied magnetic field
Zhongyang Liu, Liangliang Huang, Liang Liu, Beier Luo, Miaomiao Liang, Zhen Sun, Shu Zhu, Xin Quan, Yafeng Yang, Teng Ma, Jinghui Huang & Zhuojing Luo
Pages: 43-61
Published online: 17 Dec 2014
AbstractforActivation of Schwann cells in vitro by magnetic nanocomposites via applied magnetic field | Full Text | References | PDF (22.7 MB)
  • 81 Views
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Open Access
Article
Self-assembled polymeric nanoparticles as new, smart contrast agents for cancer early detection using magnetic resonance imaging
Fouzi Mouffouk, Teresa Simão, Daniel F Dornelles, André D Lopes, Pablo Sau, Jorge Martins, Khalid M Abu-Salah, Salman A Alrokayan, Ana M Rosa da Costa & Nuno R dos Santos
Pages: 63-76
Published online: 17 Dec 2014
AbstractforSelf-assembled polymeric nanoparticles as new, smart contrast agents for cancer early detection using magnetic resonance imaging | Full Text | References | PDF (2.7 MB)
  • 69 Views
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Open Access
Article
Detection of Mycobacterium tuberculosis based on H37Rv binding peptides using surface functionalized magnetic microspheres coupled with quantum dots – a nano detection method for Mycobacterium tuberculosis
Hua Yang, Lianhua Qin, Yilong Wang, Bingbo Zhang, Zhonghua Liu, Hui Ma, Junmei Lu, Xiaochen Huang, Donglu Shi & Zhongyi Hu
Pages: 77-88
Published online: 17 Dec 2014
AbstractforDetection of Mycobacterium tuberculosis based on H37Rv binding peptides using surface functionalized magnetic microspheres coupled with quantum dots – a nano detection method for Mycobacterium tuberculosis | Full Text | References | PDF (2.3 MB)
  • 104 Views
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Open Access
Article
Understanding greater cardiomyocyte functions on aligned compared to random carbon nanofibers in PLGA
Abdullah M Asiri, Hadi M Marwani, Sher Bahadar Khan & Thomas J Webster
Pages: 89-96
Published online: 17 Dec 2014
AbstractforUnderstanding greater cardiomyocyte functions on aligned compared to random carbon nanofibers in PLGA | Full Text | References | PDF (1.8 MB)
  • 54 Views
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Open Access

Review

Review Article
Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity
Yeon Kyung Lee, Eun-Ju Choi, Thomas J Webster, Sang-Hyun Kim & Dongwoo Khang
Pages: 97-113
Published online: 18 Dec 2014
AbstractforEffect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity | Full Text | References | PDF (6.7 MB)
  • 299 Views
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Open Access

Original Research

Article
A “turn-on” fluorescent microbead sensor for detecting nitric oxide
Lan-Hee Yang, Dong June Ahn & Eunhae Koo
Pages: 115-123
Published online: 19 Dec 2014
AbstractforA “turn-on” fluorescent microbead sensor for detecting nitric oxide | Full Text | References | PDF (2.3 MB)
  • 54 Views
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Open Access
Article
Photo activation of HPPH encapsulated in “Pocket” liposomes triggers multiple drug release and tumor cell killing in mouse breast cancer xenografts
Jessica Sine, Cordula Urban, Derek Thayer, Heather Charron, Niksa Valim, Darrell B Tata, Rachel Schiff, Robert Blumenthal, Amit Joshi & Anu Puri
Pages: 125-145
Published online: 19 Dec 2014
AbstractforPhoto activation of HPPH encapsulated in “Pocket” liposomes triggers multiple drug release and tumor cell killing in mouse breast cancer xenografts | Full Text | References | PDF (4.8 MB)
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Open Access
Article
A robust and versatile signal-on fluorescence sensing strategy based on SYBR Green I dye and graphene oxide
Huazhang Qiu, Namei Wu, Yanjie Zheng, Min Chen, Shaohuang Weng, Yuanzhong Chen & Xinhua Lin
Pages: 147-156
Published online: 22 Dec 2014
AbstractforA robust and versatile signal-on fluorescence sensing strategy based on SYBR Green I dye and graphene oxide | Full Text | References | PDF (1.8 MB)
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Open Access
Article
Magnetic single-walled carbon nanotubes as efficient drug delivery nanocarriers in breast cancer murine model: noninvasive monitoring using diffusion-weighted magnetic resonance imaging as sensitive imaging biomarker
Achraf Al Faraj, Abjal Pasha Shaik & Asma Sultana Shaik
Pages: 157-168
Published online: 23 Dec 2014
AbstractforMagnetic single-walled carbon nanotubes as efficient drug delivery nanocarriers in breast cancer murine model: noninvasive monitoring using diffusion-weighted magnetic resonance imaging as sensitive imaging biomarker | Full Text | References | PDF (3.1 MB)
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Open Access

Corrigendum

Correction
Enhanced photodynamic leishmanicidal activity of hydrophobic zinc phthalocyanine within archaeolipids containing liposomes [Corrigendum]
Page: 169
Published online: 29 Dec 2014
CitationforEnhanced photodynamic leishmanicidal activity of hydrophobic zinc phthalocyanine within archaeolipids containing liposomes [Corrigendum] | Full Text | PDF (96.5 KB)
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Open Access

Original Research

Article
RETRACTED ARTICLE: Formulation and evaluation of a topical niosomal gel containing a combination of benzoyl peroxide and tretinoin for antiacne activity
Ankush Gupta, Sima Singh, Niranjan G Kotla & Thomas J Webster
Pages: 171-182
Published online: 24 Dec 2014
AbstractforRETRACTED ARTICLE: Formulation and evaluation of a topical niosomal gel containing a combination of benzoyl peroxide and tretinoin for antiacne activity | PDF (3.4 MB)
  • 203 Views
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Open Access
Article
Effect of silica and gold nanoparticles on macrophage proliferation, activation markers, cytokine production, and phagocytosis in vitro
Simona Bancos, David L Stevens & Katherine M Tyner
Pages: 183-206
Published online: 24 Dec 2014
AbstractforEffect of silica and gold nanoparticles on macrophage proliferation, activation markers, cytokine production, and phagocytosis in vitro | Full Text | References | PDF (3.9 MB)
  • 213 Views
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Open Access
Article
Ferroferric oxide nanoparticles induce prosurvival autophagy in human blood cells by modulating the Beclin 1/Bcl-2/VPS34 complex
Min Shi, Liang Cheng, Zubin Zhang, Zhuang Liu & Xinliang Mao
Pages: 207-216
Published online: 27 Feb 2023
AbstractforFerroferric oxide nanoparticles induce prosurvival autophagy in human blood cells by modulating the Beclin 1/Bcl-2/VPS34 complex | Full Text | References | PDF (3.3 MB)
  • 53 Views
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Open Access
Article
Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
Saeideh Ebrahimiasl, Azmi Zakaria, Anuar Kassim & Sri Norleha Basri
Pages: 217-227
Published online: 30 Dec 2014
AbstractforNovel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities | Full Text | References | PDF (1.1 MB)
  • 231 Views
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Open Access
Article
Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity
Kathleen A Ross, Hyelee Loyd, Wuwei Wu, Lucas Huntimer, Shaheen Ahmed, Anthony Sambol, Scott Broderick, Zachary Flickinger, Krishna Rajan, Tatiana Bronich, Surya Mallapragada, Michael J Wannemuehler, Susan Carpenter & Balaji Narasimhan
Pages: 229-243
Published online: 30 Dec 2014
AbstractforHemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity | Full Text | References | PDF (1.1 MB)
  • 88 Views
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Open Access
Article
Nanoparticles inhibit cancer cell invasion and enhance antitumor efficiency by targeted drug delivery via cell surface-related GRP78
Liang Zhao, Hongdan Li, Yijie Shi, Guan Wang, Liwei Liu, Chang Su & Rongjian Su
Pages: 245-256
Published online: 30 Dec 2014
AbstractforNanoparticles inhibit cancer cell invasion and enhance antitumor efficiency by targeted drug delivery via cell surface-related GRP78 | Full Text | References | PDF (3.1 MB)
  • 64 Views
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Open Access
Article
Codelivery of doxorubicin and curcumin with lipid nanoparticles results in improved efficacy of chemotherapy in liver cancer
Xiaojing Zhao, Qi Chen, Wei Liu, Yusang Li, Hebin Tang, Xuhan Liu & Xiangliang Yang
Pages: 257-270
Published online: 30 Dec 2014
AbstractforCodelivery of doxorubicin and curcumin with lipid nanoparticles results in improved efficacy of chemotherapy in liver cancer | Full Text | References | PDF (3.2 MB)
  • 248 Views
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Open Access
Article
Photothermal cancer therapy using graphitic carbon–coated magnetic particles prepared by one-pot synthesis
Hyo-Jeong Lee, Jakkid Sanetuntikul, Eun-Sook Choi, Bo Ram Lee, Jung-Hee Kim, Eunjoo Kim & Sangaraju Shanmugam
Pages: 271-282
Published online: 30 Dec 2014
AbstractforPhotothermal cancer therapy using graphitic carbon–coated magnetic particles prepared by one-pot synthesis | Full Text | References | PDF (4.3 MB)
  • 65 Views
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Open Access
Article
Immobilizing osteogenic growth peptide with and without fibronectin on a titanium surface: effects of loading methods on mesenchymal stem cell differentiation
Cen Chen, Han Li, Xiangdong Kong, Sheng-Min Zhang & In-Seop Lee
Pages: 283-295
Published online: 31 Dec 2014
AbstractforImmobilizing osteogenic growth peptide with and without fibronectin on a titanium surface: effects of loading methods on mesenchymal stem cell differentiation | Full Text | References | PDF (5.6 MB)
  • 59 Views
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Open Access
Article
Evaluation of antinociceptive activity of nanoliposome-encapsulated and free-form diclofenac in rats and mice
Jun Zheng Goh, Sook Nai Tang, Hoe Siong Chiong, Yoke Keong Yong, Ahmad Zuraini & Muhammad Nazrul Hakim
Pages: 297-303
Published online: 31 Dec 2014
AbstractforEvaluation of antinociceptive activity of nanoliposome-encapsulated and free-form diclofenac in rats and mice | Full Text | References | PDF (1.5 MB)
  • 112 Views
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Open Access
Article
Preparation, in vitro and in vivo evaluation of polymeric nanoparticles based on hyaluronic acid-poly(butyl cyanoacrylate) and D-alpha-tocopheryl polyethylene glycol 1000 succinate for tumor-targeted delivery of morin hydrate
Sarra Abbad, Cheng Wang, Ayman Yahia Waddad, Huixia Lv & Jianping Zhou
Pages: 305-320
Published online: 06 Jan 2015
AbstractforPreparation, in vitro and in vivo evaluation of polymeric nanoparticles based on hyaluronic acid-poly(butyl cyanoacrylate) and D-alpha-tocopheryl polyethylene glycol 1000 succinate for tumor-targeted delivery of morin hydrate | Full Text | References | PDF (4.6 MB)
  • 141 Views
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Open Access
Article
Chitosan based atorvastatin nanocrystals: effect of cationic charge on particle size, formulation stability, and in-vivo efficacy
Mallesh Kurakula, AM El-Helw, Tariq R Sobahi & Magdy Y Abdelaal
Pages: 321-334
Published online: 06 Jan 2015
AbstractforChitosan based atorvastatin nanocrystals: effect of cationic charge on particle size, formulation stability, and in-vivo efficacy | Full Text | References | PDF (3 MB)
  • 197 Views
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Open Access
Article
Passive tumor targeting and imaging by using mercaptosuccinic acid-coated near-infrared quantum dots
Guimiao Lin, Xiaomei Wang, Feng Yin & Ken-Tye Yong
Pages: 335-345
Published online: 06 Jan 2015
AbstractforPassive tumor targeting and imaging by using mercaptosuccinic acid-coated near-infrared quantum dots | Full Text | References | PDF (2.9 MB)
  • 65 Views
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Open Access
Article
Treating cutaneous squamous cell carcinoma using 5-aminolevulinic acid polylactic-co-glycolic acid nanoparticle-mediated photodynamic therapy in a mouse model
Xiaojie Wang, Lei Shi, Qingfeng Tu, Hongwei Wang, Haiyan Zhang, Peiru Wang, Linglin Zhang, Zheng Huang, Feng Zhao, Hansen Luan & Xiuli Wang
Pages: 347-355
Published online: 06 Jan 2015
AbstractforTreating cutaneous squamous cell carcinoma using 5-aminolevulinic acid polylactic-co-glycolic acid nanoparticle-mediated photodynamic therapy in a mouse model | Full Text | References | PDF (8.9 MB)
  • 81 Views
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Open Access
Article
Antibiotic and chemotherapeutic enhanced three-dimensional printer filaments and constructs for biomedical applications
Jeffery A Weisman, James C Nicholson, Karthik Tappa, UdayaBhanu Jammalamadaka, Chester G Wilson & David K Mills
Pages: 357-370
Published online: 09 Jan 2015
AbstractforAntibiotic and chemotherapeutic enhanced three-dimensional printer filaments and constructs for biomedical applications | Full Text | References | PDF (7 MB)
  • 236 Views
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Open Access
Article
Cationic additives in nanosystems activate cytotoxicity and inflammatory response of human neutrophils: lipid nanoparticles versus polymeric nanoparticles
Tsong-Long Hwang, Ibrahim A Aljuffali, Chwan-Fwu Lin, Yuan-Ting Chang & Jia-You Fang
Pages: 371-385
Published online: 07 Jan 2015
AbstractforCationic additives in nanosystems activate cytotoxicity and inflammatory response of human neutrophils: lipid nanoparticles versus polymeric nanoparticles | Full Text | References | PDF (1.7 MB)
  • 113 Views
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Open Access
Article
Molecular photoacoustic imaging of breast cancer using an actively targeted conjugated polymer
Ghayathri Balasundaram, Chris Jun Hui Ho, Kai Li, Wouter Driessen, US Dinish, Chi Lok Wong, Vasilis Ntziachristos, Bin Liu & Malini Olivo
Pages: 387-397
Published online: 08 Jan 2015
AbstractforMolecular photoacoustic imaging of breast cancer using an actively targeted conjugated polymer | Full Text | References | PDF (1.5 MB)
  • 85 Views
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Open Access
Article
Detection of a fluorescent-labeled avidin-nucleic acid nanoassembly by confocal laser endomicroscopy in the microvasculature of chronically inflamed intestinal mucosa
Andrea Buda, Sonia Facchin, Elisa Dassie, Elisabetta Casarin, Mark A Jepson, Helmut Neumann, Giorgia Hatem, Stefano Realdon, Renata D’Incà, Giacomo Carlo Sturniolo & Margherita Morpurgo
Pages: 399-408
Published online: 08 Jan 2015
AbstractforDetection of a fluorescent-labeled avidin-nucleic acid nanoassembly by confocal laser endomicroscopy in the microvasculature of chronically inflamed intestinal mucosa | Full Text | References | PDF (3.8 MB)
  • 47 Views
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Open Access
Article
Increased cardiac distribution of mono-PEGylated Radix Ophiopogonis polysaccharide in both myocardial infarction and ischemia/reperfusion rats
ChunXia Yao, XiaoLi Shi, Xiao Lin, Lan Shen, DeSheng Xu & Yi Feng
Pages: 409-418
Published online: 27 Feb 2023
AbstractforIncreased cardiac distribution of mono-PEGylated Radix Ophiopogonis polysaccharide in both myocardial infarction and ischemia/reperfusion rats | Full Text | References | PDF (860.2 KB)
  • 49 Views
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Open Access
Article
Effective near-infrared photodynamic therapy assisted by upconversion nanoparticles conjugated with photosensitizers
Qing Qing Dou, Choon Peng Teng, Enyi Ye & Xian Jun Loh
Pages: 419-432
Published online: 08 Jan 2015
AbstractforEffective near-infrared photodynamic therapy assisted by upconversion nanoparticles conjugated with photosensitizers | Full Text | References | PDF (5.7 MB)
  • 169 Views
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Open Access
Article
Barium titanate nanoparticles and hypergravity stimulation improve differentiation of mesenchymal stem cells into osteoblasts
Antonella Rocca, Attilio Marino, Veronica Rocca, Stefania Moscato, Giuseppe de Vito, Vincenzo Piazza, Barbara Mazzolai, Virgilio Mattoli, Thu Jennifer Ngo-Anh & Gianni Ciofani
Pages: 433-445
Published online: 08 Jan 2015
AbstractforBarium titanate nanoparticles and hypergravity stimulation improve differentiation of mesenchymal stem cells into osteoblasts | Full Text | References | PDF (6.2 MB)
  • 93 Views
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Open Access
Article
Inhibited biofilm formation and improved antibacterial activity of a novel nanoemulsion against cariogenic Streptococcus mutans in vitro and in vivo
Yun Fei Li, Hong Wu Sun, Rong Gao, Kai Yun Liu, Hua Qi Zhang, Qi Huan Fu, Sheng Li Qing, Gang Guo & Quan Ming Zou
Pages: 447-462
Published online: 27 Feb 2023
AbstractforInhibited biofilm formation and improved antibacterial activity of a novel nanoemulsion against cariogenic Streptococcus mutans in vitro and in vivo | Full Text | References | PDF (12.7 MB)
  • 136 Views
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Open Access
Article
Evaluation of 188Re-labeled PEGylated nanoliposome as a radionuclide therapeutic agent in an orthotopic glioma-bearing rat model
Feng-Yun J Huang, Te-Wei Lee, Chih-Hsien Chang, Liang-Cheng Chen, Wei-Hsin Hsu, Chien-Wen Chang & Jem-Mau Lo
Pages: 463-473
Published online: 27 Feb 2023
AbstractforEvaluation of 188Re-labeled PEGylated nanoliposome as a radionuclide therapeutic agent in an orthotopic glioma-bearing rat model | Full Text | References | PDF (1.6 MB)
  • 70 Views
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Open Access
Article
Nanoencapsulation of pomegranate bioactive compounds for breast cancer chemoprevention
Amit B Shirode, Dhruba J Bharali, Sameera Nallanthighal, Justin K Coon, Shaker A Mousa & Ramune Reliene
Pages: 475-484
Published online: 27 Feb 2023
AbstractforNanoencapsulation of pomegranate bioactive compounds for breast cancer chemoprevention | Full Text | References | PDF (1,007 KB)
  • 251 Views
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Open Access
Article
Effect of nanofiber content on bone regeneration of silk fibroin/poly(ε-caprolactone) nano/microfibrous composite scaffolds
Beom Su Kim, Ko Eun Park, Min Hee Kim, Hyung Keun You, Jun Lee & Won Ho Park
Pages: 485-502
Published online: 09 Jan 2015
AbstractforEffect of nanofiber content on bone regeneration of silk fibroin/poly(ε-caprolactone) nano/microfibrous composite scaffolds | Full Text | References | PDF (14.1 MB)
  • 103 Views
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Article
Characterization of the host–guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin–gemini surfactant and evaluation of its anticancer activity
Masoomeh Poorghorban, Umashankar Das, Osama Alaidi, Jackson M Chitanda, Deborah Michel, Jonathan Dimmock, Ronald Verrall, Pawel Grochulski & Ildiko Badea
Pages: 503-515
Published online: 27 Feb 2023
AbstractforCharacterization of the host–guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin–gemini surfactant and evaluation of its anticancer activity | Full Text | References | PDF (3.2 MB)
  • 126 Views
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Open Access
Article
BMP2-loaded hollow hydroxyapatite microspheres exhibit enhanced osteoinduction and osteogenicity in large bone defects
Long Xiong, Jianhua Zeng, Aihua Yao, Qiquan Tu, Jingtang Li, Liang Yan & Zhiming Tang
Pages: 517-526
Published online: 12 Jan 2015
AbstractforBMP2-loaded hollow hydroxyapatite microspheres exhibit enhanced osteoinduction and osteogenicity in large bone defects | Full Text | References | PDF (5.6 MB)
  • 82 Views
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Article
Molecular plasma deposition: biologically inspired nanohydroxyapatite coatings on anodized nanotubular titanium for improving osteoblast density
Ganesan Balasundaram, Daniel M Storey & Thomas J Webster
Pages: 527-535
Published online: 27 Feb 2023
AbstractforMolecular plasma deposition: biologically inspired nanohydroxyapatite coatings on anodized nanotubular titanium for improving osteoblast density | Full Text | References | PDF (4.3 MB)
  • 48 Views
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Open Access
Article
Surface-enhanced Raman spectroscopy of saliva proteins for the noninvasive differentiation of benign and malignant breast tumors
Shangyuan Feng, Shaohua Huang, Duo Lin, Guannan Chen, Yuanji Xu, Yongzeng Li, Zufang Huang, Jianji Pan, Rong Chen & Haishan Zeng
Pages: 537-547
Published online: 12 Jan 2015
AbstractforSurface-enhanced Raman spectroscopy of saliva proteins for the noninvasive differentiation of benign and malignant breast tumors | Full Text | References | PDF (1.4 MB)
  • 204 Views
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Article
Oxidative stress and antibacterial properties of a graphene oxide-cystamine nanohybrid
Sitansu Sekhar Nanda, Seong Soo A An & Dong Kee Yi
Pages: 549-556
Published online: 27 Feb 2023
AbstractforOxidative stress and antibacterial properties of a graphene oxide-cystamine nanohybrid | Full Text | References | PDF (1.9 MB)
  • 113 Views
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Article
PLGA-PLL-PEG-Tf-based targeted nanoparticles drug delivery system enhance antitumor efficacy via intrinsic apoptosis pathway
Wen Bao, Ran Liu, Yonglu Wang, Fei Wang, Guohua Xia, Haijun Zhang, Xueming Li, Haixiang Yin & Baoan Chen
Pages: 557-566
Published online: 12 Jan 2015
AbstractforPLGA-PLL-PEG-Tf-based targeted nanoparticles drug delivery system enhance antitumor efficacy via intrinsic apoptosis pathway | Full Text | References | PDF (4.1 MB)
  • 106 Views
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Article
Response of human mesenchymal stem cells to intrafibrillar nanohydroxyapatite content and extrafibrillar nanohydroxyapatite in biomimetic chitosan/silk fibroin/nanohydroxyapatite nanofibrous membrane scaffolds
Guo-Jyun Lai, KT Shalumon & Jyh-Ping Chen
Pages: 567-584
Published online: 12 Jan 2015
AbstractforResponse of human mesenchymal stem cells to intrafibrillar nanohydroxyapatite content and extrafibrillar nanohydroxyapatite in biomimetic chitosan/silk fibroin/nanohydroxyapatite nanofibrous membrane scaffolds | Full Text | References | PDF (6.7 MB)
  • 115 Views
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Article
Oil-in-water biocompatible microemulsion as a carrier for the antitumor drug compound methyl dihydrojasmonate
Gisela Bevilacqua Rolfsen Ferreira da Silva, Maria Virginia Scarpa, Iracilda Zepone Carlos, Marcela Bassi Quilles, Raphael Carlos Comeli Lia, Eryvaldo Socrates Tabosa do Egito & Anselmo Gomes de Oliveira
Pages: 585-594
Published online: 12 Jan 2015
AbstractforOil-in-water biocompatible microemulsion as a carrier for the antitumor drug compound methyl dihydrojasmonate | Full Text | References | PDF (2 MB)
  • 68 Views
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Erratum

Correction
Synthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes [Erratum]
Page: 595
Published online: 14 Jan 2015
CitationforSynthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes [Erratum] | Full Text | PDF (105 KB)
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Original Research

Article
Stability and toxicity of empty or gene-loaded lipopolysaccharide-amine nanopolymersomes
Qinmei Wang, Ying Chen, Lichun Wang, Xinchun Zhang, Hongzhang Huang & Wei Teng
Pages: 597-608
Published online: 13 Jan 2015
AbstractforStability and toxicity of empty or gene-loaded lipopolysaccharide-amine nanopolymersomes | Full Text | References | PDF (2.2 MB)
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Article
Conjugation of cell-penetrating peptides with poly(lactic-co-glycolic acid)-polyethylene glycol nanoparticles improves ocular drug delivery
Aimee Vasconcelos, Estefania Vega, Yolanda Pérez, María J Gómara, María Luisa García & Isabel Haro
Pages: 609-631
Published online: 27 Jan 2015
AbstractforConjugation of cell-penetrating peptides with poly(lactic-co-glycolic acid)-polyethylene glycol nanoparticles improves ocular drug delivery | Full Text | References | PDF (2.6 MB)
  • 252 Views
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Article
Lower irritation microemulsion-based rotigotine gel: formulation optimization and in vitro and in vivo studies
Zheng Wang, Hong-Jie Mu, Xue-Mei Zhang, Peng-Kai Ma, Sheng-Nan Lian, Feng-Pu Zhang, Sheng-Ying Chu, Wen-Wen Zhang, Ai-Ping Wang, Wen-Yan Wang & Kao-Xiang Sun
Pages: 633-644
Published online: 14 Jan 2015
AbstractforLower irritation microemulsion-based rotigotine gel: formulation optimization and in vitro and in vivo studies | Full Text | References | PDF (3.7 MB)
  • 140 Views
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Article
Protein immobilization onto electrochemically synthesized CoFe nanowires
Sri Ramulu Torati, Venu Reddy, Seok Soo Yoon & CheolGi Kim
Pages: 645-651
Published online: 14 Jan 2015
AbstractforProtein immobilization onto electrochemically synthesized CoFe nanowires | Full Text | References | PDF (1.6 MB)
  • 56 Views
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Article
Ag-plasma modification enhances bone apposition around titanium dental implants: an animal study in Labrador dogs
Shichong Qiao, Huiliang Cao, Xu Zhao, Hueiwen Lo, Longfei Zhuang, Yingxin Gu, Junyu Shi, Xuanyong Liu & Hongchang Lai
Pages: 653-664
Published online: 14 Jan 2015
AbstractforAg-plasma modification enhances bone apposition around titanium dental implants: an animal study in Labrador dogs | Full Text | References | PDF (7.6 MB)
  • 71 Views
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Article
Specific targeting of A54 homing peptide-functionalized dextran-g-poly(lactic-co-glycolic acid) micelles to tumor cells
Jun-Qing Situ, Yi-Qing Ye, Xiu-Liang Zhu, Ri-Sheng Yu, Jian You, Hong Yuan, Fu-Qiang Hu & Yong-Zhong Du
Pages: 665-675
Published online: 17 Jan 2015
AbstractforSpecific targeting of A54 homing peptide-functionalized dextran-g-poly(lactic-co-glycolic acid) micelles to tumor cells | Full Text | References | PDF (3.4 MB)
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Article
Electrochemical sensing method for point-of-care cortisol detection in human immunodeficiency virus-infected patients
Ajeet Kaushik, Adriana Yndart, Rahul Dev Jayant, Vidya Sagar, Venkata Atluri, Shekhar Bhansali & Madhavan Nair
Pages: 677-685
Published online: 19 Jan 2015
AbstractforElectrochemical sensing method for point-of-care cortisol detection in human immunodeficiency virus-infected patients | Full Text | References | PDF (2.4 MB)
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Article
The effect of blood protein adsorption on cellular uptake of anatase TiO2 nanoparticles
Zouhir E Allouni, Nils R Gjerdet, Mihaela R Cimpan & Paul J Høl
Pages: 687-695
Published online: 19 Jan 2015
AbstractforThe effect of blood protein adsorption on cellular uptake of anatase TiO2 nanoparticles | Full Text | References | PDF (1.7 MB)
  • 84 Views
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Article
Physicochemical and biological properties of a novel injectable polyurethane system for root canal filling
Jian Wang, Yi Zuo, Minghui Zhao, Jiaxing Jiang, Yi Man, Jun Wu, Yunjiu Hu, Changlei Liu, Yubao Li & Jidong Li
Pages: 697-709
Published online: 17 Jan 2015
AbstractforPhysicochemical and biological properties of a novel injectable polyurethane system for root canal filling | Full Text | References | PDF (3.5 MB)
  • 86 Views
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Article
Fluorescent magnetic iron oxide nanoparticles for cardiac precursor cell selection from stromal vascular fraction and optimization for magnetic resonance imaging
Vinod Kumar Verma, Suguna Ratnakar Kamaraju, Ravindranath Kancherla, Lakshmi K Kona, Syed Sultan Beevi, Tanya Debnath, Shalini P Usha, Rammohan Vadapalli, Ali Syed Arbab & Lakshmi Kiran Chelluri
Pages: 711-726
Published online: 20 Jan 2015
AbstractforFluorescent magnetic iron oxide nanoparticles for cardiac precursor cell selection from stromal vascular fraction and optimization for magnetic resonance imaging | Full Text | References | PDF (9.9 MB)
  • 82 Views
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Article
Antibacterial activity and biological performance of a novel antibacterial coating containing a halogenated furanone compound loaded poly(L-lactic acid) nanoparticles on microarc-oxidized titanium
Yicheng Cheng, Xianghui Zhao, Xianghui Liu, Weige Sun, Huifang Ren, Bo Gao & Jiang Wu
Pages: 727-737
Published online: 19 Jan 2015
AbstractforAntibacterial activity and biological performance of a novel antibacterial coating containing a halogenated furanone compound loaded poly(L-lactic acid) nanoparticles on microarc-oxidized titanium | Full Text | References | PDF (8.6 MB)
  • 68 Views
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Article
PEGylated apoptotic protein-loaded PLGA microspheres for cancer therapy
Hyeong Jun Byeon, Insoo Kim, Ji Su Choi, Eun Seong Lee, Beom Soo Shin & Yu Seok Youn
Pages: 739-748
Published online: 19 Jan 2015
AbstractforPEGylated apoptotic protein-loaded PLGA microspheres for cancer therapy | Full Text | References | PDF (4.2 MB)
  • 66 Views
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Article
Bio-functionalized dense-silica nanoparticles for MR/NIRF imaging of CD146 in gastric cancer
Pu Wang, Yazhuo Qu, Chuan Li, Li Yin, Caifei Shen, Wei Chen, Shiming Yang, Xiuwu Bian & Dianchun Fang
Pages: 749-763
Published online: 20 Jan 2015
AbstractforBio-functionalized dense-silica nanoparticles for MR/NIRF imaging of CD146 in gastric cancer | Full Text | References | PDF (11.2 MB)
  • 62 Views
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Article
Physicochemical properties, cytotoxicity, and antimicrobial activity of sulphated zirconia nanoparticles
Ae Mftah, Fatah H Alhassan, Mothanna Sadiq Al-Qubaisi, Mohamed Ezzat El Zowalaty, Thomas J Webster, Mohammed Sh-eldin, Abdullah Rasedee, Yun Hin Taufiq-Yap & Shah Samiur Rashid
Pages: 765-774
Published online: 19 Jan 2015
AbstractforPhysicochemical properties, cytotoxicity, and antimicrobial activity of sulphated zirconia nanoparticles | Full Text | References | PDF (2.9 MB)
  • 159 Views
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Article
Glycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake
Surya P Lamichhane, Neha Arya, Nirdesh Ojha, Esther Kohler & V Prasad Shastri
Pages: 775-789
Published online: 19 Jan 2015
AbstractforGlycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake | Full Text | References | PDF (4.3 MB)
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Review

Review Article
Clinical and pathological implications of miRNA in bladder cancer
Cornelia Braicu, Roxana Cojocneanu-Petric, Sergiu Chira, Anamaria Truta, Alexandru Floares, Bogdan Petrut, Patriciu Achimas-Cadariu & Ioana Berindan-Neagoe
Pages: 791-800
Published online: 20 Jan 2015
AbstractforClinical and pathological implications of miRNA in bladder cancer | Full Text | References | PDF (1.2 MB)
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Original Research

Article
Empirical modeling of the fine particle fraction for carrier-based pulmonary delivery formulations
Adam Pacławski, Jakub Szlęk, Raymond Lau, Renata Jachowicz & Aleksander Mendyk
Pages: 801-810
Published online: 21 Jan 2015
AbstractforEmpirical modeling of the fine particle fraction for carrier-based pulmonary delivery formulations | Full Text | References | PDF (2.4 MB)
  • 103 Views
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Article
Multifunction hexagonal liquid-crystal containing modified surface TiO2 nanoparticles and terpinen-4-ol for controlled release
Eloísa Berbel Manaia, Renata Cristina Kiatkoski Kaminski, Anselmo Gomes de Oliveira, Marcos Antonio Corrêa & Leila Aparecida Chiavacci
Pages: 811-819
Published online: 22 Jan 2015
AbstractforMultifunction hexagonal liquid-crystal containing modified surface TiO2 nanoparticles and terpinen-4-ol for controlled release | Full Text | References | PDF (4.7 MB)
  • 73 Views
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Article
The efficacy and mechanism of apoptosis induction by hypericin-mediated sonodynamic therapy in THP-1 macrophages
Xuesong Li, Lei Gao, Longbin Zheng, Jiayuan Kou, Xing Zhu, Yueqing Jiang, Zhaoyu Zhong, Juhua Dan, Haobo Xu, Yang Yang, Hong Li, Sa Shi, Wenwu Cao, Yajun Zhao, Ye Tian & Liming Yang
Pages: 821-838
Published online: 22 Jan 2015
AbstractforThe efficacy and mechanism of apoptosis induction by hypericin-mediated sonodynamic therapy in THP-1 macrophages | Full Text | References | PDF (5.8 MB)
  • 91 Views
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Article
In vivo experimental study on bone regeneration in critical bone defects using PIB nanogels/boron-containing mesoporous bioactive glass composite scaffold
Xiaohui Chen, Yanbing Zhao, Shinan Geng, Richard J Miron, Qiao Zhang, Chengtie Wu & Yufeng Zhang
Pages: 839-846
Published online: 22 Jan 2015
AbstractforIn vivo experimental study on bone regeneration in critical bone defects using PIB nanogels/boron-containing mesoporous bioactive glass composite scaffold | Full Text | References | PDF (2.1 MB)
  • 134 Views
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Article
Self-assembling surfactant-like peptide A6K as potential delivery system for hydrophobic drugs
Yongzhu Chen, Chengkang Tang, Jie Zhang, Meng Gong, Bo Su & Feng Qiu
Pages: 847-858
Published online: 23 Jan 2015
AbstractforSelf-assembling surfactant-like peptide A6K as potential delivery system for hydrophobic drugs | Full Text | References | PDF (8 MB)
  • 65 Views
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Article
Robotic voltammetry with carbon nanotube-based sensors: a superb blend for convenient high-quality antimicrobial trace analysis
Somjai Theanponkrang, Wipa Suginta, Helge Weingart, Mathias Winterhalter & Albert Schulte
Pages: 859-868
Published online: 27 Jan 2015
AbstractforRobotic voltammetry with carbon nanotube-based sensors: a superb blend for convenient high-quality antimicrobial trace analysis | Full Text | References | PDF (2.5 MB)
  • 57 Views
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Article
Osteogenic cell differentiation on H-terminated and O-terminated nanocrystalline diamond films
Jana Liskova, Oleg Babchenko, Marian Varga, Alexander Kromka, Daniel Hadraba, Zdenek Svindrych, Zuzana Burdikova & Lucie Bacakova
Pages: 869-884
Published online: 27 Jan 2015
AbstractforOsteogenic cell differentiation on H-terminated and O-terminated nanocrystalline diamond films | Full Text | References | PDF (10.4 MB)
  • 71 Views
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Article
Sustained release of vancomycin from novel biodegradable nanofiber-loaded vascular prosthetic grafts: in vitro and in vivo study
Kuo-Sheng Liu, Cheng-Hung Lee, Yi-Chuan Wang & Shih-Jung Liu
Pages: 885-891
Published online: 29 Jan 2015
AbstractforSustained release of vancomycin from novel biodegradable nanofiber-loaded vascular prosthetic grafts: in vitro and in vivo study | Full Text | References | PDF (1.8 MB)
  • 77 Views
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Article
Design and formulation of a topical hydrogel integrating lemongrass-loaded nanosponges with an enhanced antifungal effect: in vitro/in vivo evaluation
Hibah M Aldawsari, Shaimaa M Badr-Eldin, Gihan S Labib & Amal H El-Kamel
Pages: 893-902
Published online: 29 Jan 2015
AbstractforDesign and formulation of a topical hydrogel integrating lemongrass-loaded nanosponges with an enhanced antifungal effect: in vitro/in vivo evaluation | Full Text | References | PDF (1.5 MB)
  • 607 Views
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Article
Liver-targeted cyclosporine A-encapsulated poly (lactic-co-glycolic) acid nanoparticles inhibit hepatitis C virus replication
KR Jyothi, Jagadish Beloor, Ara Jo, Minh Nam Nguyen, Tae Gyu Choi, Jin-Hwan Kim, Salima Akter, Sang-Kyung Lee, Chi Hoon Maeng, Hyung Hwan Baik, Insug Kang, Joohun Ha & Sung Soo Kim
Pages: 903-921
Published online: 27 Feb 2023
AbstractforLiver-targeted cyclosporine A-encapsulated poly (lactic-co-glycolic) acid nanoparticles inhibit hepatitis C virus replication | Full Text | References | PDF (2.6 MB)
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Review

Review Article
Nanomedicine strategies for treatment of secondary spinal cord injury
Désirée White-Schenk, Riyi Shi & James F Leary
Pages: 923-938
Published online: 29 Jan 2015
AbstractforNanomedicine strategies for treatment of secondary spinal cord injury | Full Text | References | PDF (1.2 MB)
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Article
Nanocomplexation of thrombin with cationic amylose derivative for improved stability and hemostatic efficacy
Baoxiong Zhuang, Zhihua Li, Jiadong Pang, Wenbin Li, Pinbo Huang, Jie Wang, Yu Zhou, Qing Lin, Quanbo Zhou, Xiao Ye, Huilin Ye, Yimin Liu, Li-Ming Zhang & Rufu Chen
Pages: 939-947
Published online: 29 Jan 2015
AbstractforNanocomplexation of thrombin with cationic amylose derivative for improved stability and hemostatic efficacy | Full Text | References | PDF (4.3 MB)
  • 47 Views
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Article
In vitro cytotoxicity analysis of doxorubicin-loaded/superparamagnetic iron oxide colloidal nanoassemblies on MCF7 and NIH3T3 cell lines
Katerina Tomankova, Katerina Polakova, Klara Pizova, Svatopluk Binder, Marketa Havrdova, Mary Kolarova, Eva Kriegova, Jana Zapletalova, Lukas Malina, Jana Horakova, Jakub Malohlava, Argiris Kolokithas-Ntoukas, Aristides Bakandritsos, Hana Kolarova & Radek Zboril
Pages: 949-961
Published online: 29 Jan 2015
AbstractforIn vitro cytotoxicity analysis of doxorubicin-loaded/superparamagnetic iron oxide colloidal nanoassemblies on MCF7 and NIH3T3 cell lines | Full Text | References | PDF (2.5 MB)
  • 244 Views
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Article
Synthesis and extracellular accumulation of silver nanoparticles by employing radiation-resistant Deinococcus radiodurans, their characterization, and determination of bioactivity
Rasika R Kulkarni, Nayana S Shaiwale, Dileep N Deobagkar & Deepti D Deobagkar
Pages: 963-974
Published online: 29 Jan 2015
AbstractforSynthesis and extracellular accumulation of silver nanoparticles by employing radiation-resistant Deinococcus radiodurans, their characterization, and determination of bioactivity | Full Text | References | PDF (3 MB)
  • 153 Views
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Review Article
Liposomes as nanomedical devices
Giuseppina Bozzuto & Agnese Molinari
Pages: 975-999
Published online: 02 Feb 2015
AbstractforLiposomes as nanomedical devices | Full Text | References | PDF (3 MB)
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Review Article
Polymeric nanoparticles for targeted treatment in oncology: current insights
Rashmi H Prabhu, Vandana B Patravale & Medha D Joshi
Pages: 1001-1018
Published online: 02 Feb 2015
AbstractforPolymeric nanoparticles for targeted treatment in oncology: current insights | Full Text | References | PDF (1.2 MB)
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Original Research

Article
Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model
Kislay Roy, Rupinder K Kanwar, Subramanian Krishnakumar, Chun Hei Antonio Cheung & Jagat R Kanwar
Pages: 1019-1043
Published online: 02 Feb 2015
AbstractforCompetitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model | Full Text | References | PDF (9.9 MB)
  • 62 Views
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Article
A novel chemosynthetic peptide with β-sheet motif efficiently kills Klebsiella pneumoniae in a mouse model
Shirui Tan, Changpei Gan, Rongpeng Li, Yan Ye, Shuang Zhang, Xu Wu, Yi Yan Yang, Weimin Fan & Min Wu
Pages: 1045-1059
Published online: 09 Feb 2015
AbstractforA novel chemosynthetic peptide with β-sheet motif efficiently kills Klebsiella pneumoniae in a mouse model | Full Text | References | PDF (3.4 MB)
  • 66 Views
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Article
A living thick nanofibrous implant bifunctionalized with active growth factor and stem cells for bone regeneration
Sandy Eap, Laetitia Keller, Jessica Schiavi, Olivier Huck, Leandro Jacomine, Florence Fioretti, Christian Gauthier, Victor Sebastian, Pascale Schwinté & Nadia Benkirane-Jessel
Pages: 1061-1075
Published online: 04 Feb 2015
AbstractforA living thick nanofibrous implant bifunctionalized with active growth factor and stem cells for bone regeneration | Full Text | References | PDF (7.8 MB)
  • 65 Views
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Article
Sustained-release nanoART formulation for the treatment of neuroAIDS
Rahul Dev Jayant, Venkata SR Atluri, Marisela Agudelo, Vidya Sagar, Ajeet Kaushik & Madhavan Nair
Pages: 1077-1093
Published online: 04 Feb 2015
AbstractforSustained-release nanoART formulation for the treatment of neuroAIDS | Full Text | References | PDF (5.4 MB)
  • 150 Views
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Article
Titanium dioxide nanoparticles enhance production of superoxide anion and alter the antioxidant system in human osteoblast cells
Karolina Niska, Katarzyna Pyszka, Cecylia Tukaj, Michal Wozniak, Marek Witold Radomski & Iwona Inkielewicz-Stepniak
Pages: 1095-1107
Published online: 04 Feb 2015
AbstractforTitanium dioxide nanoparticles enhance production of superoxide anion and alter the antioxidant system in human osteoblast cells | Full Text | References | PDF (3.9 MB)
  • 123 Views
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Article
Effects of homogenization process parameters on physicochemical properties of astaxanthin nanodispersions prepared using a solvent-diffusion technique
Navideh Anarjan, Hoda Jafarizadeh-Malmiri, Imededdine Arbi Nehdi, Hassen Mohamed Sbihi, Saud Ibrahim Al-Resayes & Chin Ping Tan
Pages: 1109-1118
Published online: 04 Feb 2015
AbstractforEffects of homogenization process parameters on physicochemical properties of astaxanthin nanodispersions prepared using a solvent-diffusion technique | Full Text | References | PDF (1.4 MB)
  • 101 Views
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Article
Dimensionality reduction, and function approximation of poly(lactic-co-glycolic acid) micro- and nanoparticle dissolution rate
Varun Kumar Ojha, Konrad Jackowski, Ajith Abraham & Václav Snášel
Pages: 1119-1129
Published online: 04 Feb 2015
AbstractforDimensionality reduction, and function approximation of poly(lactic-co-glycolic acid) micro- and nanoparticle dissolution rate | Full Text | References | PDF (417.6 KB)
  • 52 Views
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Article
Positive impact of IGF-1-coupled nanoparticles on the differentiation potential of human chondrocytes cultured on collagen scaffolds
Juliane Pasold, Kathleen Zander, Benjamin Heskamp, Cordula Grüttner, Frank Lüthen, Thomas Tischer, Anika Jonitz-Heincke & Rainer Bader
Pages: 1131-1143
Published online: 04 Feb 2015
AbstractforPositive impact of IGF-1-coupled nanoparticles on the differentiation potential of human chondrocytes cultured on collagen scaffolds | Full Text | References | PDF (2.8 MB)
  • 85 Views
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Article
Improved osseointegration of dental titanium implants by TiO2 nanotube arrays with recombinant human bone morphogenetic protein-2: a pilot in vivo study
Jae-Kwan Lee, Dong-Soon Choi, Insan Jang & Won-Youl Choi
Pages: 1145-1154
Published online: 05 Feb 2015
AbstractforImproved osseointegration of dental titanium implants by TiO2 nanotube arrays with recombinant human bone morphogenetic protein-2: a pilot in vivo study | Full Text | References | PDF (8.5 MB)
  • 126 Views
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Article
High molecular weight chitosan derivative polymeric micelles encapsulating superparamagnetic iron oxide for tumor-targeted magnetic resonance imaging
Yunbin Xiao, Zuan Tao Lin, Yanmei Chen, He Wang, Ya Li Deng, D Elizabeth Le, Jianguo Bin, Meiyu Li, Yulin Liao, Yili Liu, Gangbiao Jiang & Jianping Bin
Pages: 1155-1172
Published online: 05 Feb 2015
AbstractforHigh molecular weight chitosan derivative polymeric micelles encapsulating superparamagnetic iron oxide for tumor-targeted magnetic resonance imaging | Full Text | References | PDF (10.9 MB)
  • 92 Views
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Article
Microemulsion-based synergistic dual-drug codelivery system for enhanced apoptosis of tumor cells
Ding Qu, Yihua Ma, Wenjie Sun, Yan Chen, Jing Zhou, Congyan Liu & Mengmeng Huang
Pages: 1173-1187
Published online: 05 Feb 2015
AbstractforMicroemulsion-based synergistic dual-drug codelivery system for enhanced apoptosis of tumor cells | Full Text | References | PDF (4.5 MB)
  • 103 Views
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Article
Thickness-controllable electrospun fibers promote tubular structure formation by endothelial progenitor cells
Jong Kyu Hong, Ju Yup Bang, Guan Xu, Jun-Hee Lee, Yeon-Ju Kim, Ho-Jun Lee, Han Seong Kim & Sang-Mo Kwon
Pages: 1189-1200
Published online: 10 Feb 2015
AbstractforThickness-controllable electrospun fibers promote tubular structure formation by endothelial progenitor cells | Full Text | References | PDF (6.5 MB)
  • 63 Views
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Article
Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors
Huali Wu, Jeffrey R Infante, Vicki L Keedy, Suzanne F Jones, Emily Chan, Johanna C Bendell, Wooin Lee, Whitney P Kirschbrown, Beth A Zamboni, Satoshi Ikeda, Hiroshi Kodaira, Mace L Rothenberg, Howard A Burris III & William C Zamboni
Pages: 1201-1209
Published online: 10 Feb 2015
AbstractforFactors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors | Full Text | References | PDF (473.6 KB)
  • 75 Views
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Article
Improving intranasal delivery of neurological nanomedicine to the olfactory region using magnetophoretic guidance of microsphere carriers
Jinxiang Xi, Ze Zhang & Xiuhua A Si
Pages: 1211-1222
Published online: 10 Feb 2015
AbstractforImproving intranasal delivery of neurological nanomedicine to the olfactory region using magnetophoretic guidance of microsphere carriers | Full Text | References | PDF (4 MB)
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Article
Targeted lung cancer therapy: preparation and optimization of transferrin-decorated nanostructured lipid carriers as novel nanomedicine for co-delivery of anticancer drugs and DNA
Zhenyu Shao, Jingyu Shao, Bingxu Tan, Shanghui Guan, Zhulong Liu, Zengjun Zhao, Fangfang He & Jian Zhao
Pages: 1223-1233
Published online: 11 Feb 2015
AbstractforTargeted lung cancer therapy: preparation and optimization of transferrin-decorated nanostructured lipid carriers as novel nanomedicine for co-delivery of anticancer drugs and DNA | Full Text | References | PDF (1.5 MB)
  • 321 Views
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Article
Comparison of three magnetic nanoparticle tracers for sentinel lymph node biopsy in an in vivo porcine model
Joost J Pouw, Muneer Ahmed, Bauke Anninga, Kimberley Schuurman, Sarah E Pinder, Mieke Van Hemelrijck, Quentin A Pankhurst, Michael Douek & Bennie ten Haken
Pages: 1235-1243
Published online: 11 Feb 2015
AbstractforComparison of three magnetic nanoparticle tracers for sentinel lymph node biopsy in an in vivo porcine model | Full Text | References | PDF (1.9 MB)
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Review Article
Nanopharmaceuticals (part 2): products in the pipeline
Volkmar Weissig & Diana Guzman-Villanueva
Pages: 1245-1257
Published online: 27 Feb 2023
AbstractforNanopharmaceuticals (part 2): products in the pipeline | Full Text | References | PDF (2.7 MB)
  • 111 Views
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Article
Targeting and treatment of glioblastomas with human mesenchymal stem cells carrying ferrociphenol lipid nanocapsules
Anne Clavreul, Angélique Montagu, Anne-Laure Lainé, Clément Tétaud, Nolwenn Lautram, Florence Franconi, Catherine Passirani, Anne Vessières, Claudia N Montero-Menei & Philippe Menei
Pages: 1259-1271
Published online: 12 Feb 2015
AbstractforTargeting and treatment of glioblastomas with human mesenchymal stem cells carrying ferrociphenol lipid nanocapsules | Full Text | References | PDF (2.9 MB)
  • 61 Views
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Article
Layer-by-layer paper-stacking nanofibrous membranes to deliver adipose-derived stem cells for bone regeneration
Wenbing Wan, Shiwen Zhang, Liangpeng Ge, Qingtao Li, Xingxing Fang, Quan Yuan, Wen Zhong, Jun Ouyang & Malcolm Xing
Pages: 1273-1290
Published online: 12 Feb 2015
AbstractforLayer-by-layer paper-stacking nanofibrous membranes to deliver adipose-derived stem cells for bone regeneration | Full Text | References | PDF (10 MB)
  • 72 Views
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Article
Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly(butylcyanoacrylate) nanoparticles
Laura Cabeza, Raúl Ortiz, José L Arias, Jose Prados, Maria Adolfina Ruiz Martínez, José M Entrena, Raquel Luque & Consolación Melguizo
Pages: 1291-1306
Published online: 13 Feb 2015
AbstractforEnhanced antitumor activity of doxorubicin in breast cancer through the use of poly(butylcyanoacrylate) nanoparticles | Full Text | References | PDF (3.8 MB)
  • 133 Views
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Article
Interstitial diffuse radiance spectroscopy of gold nanocages and nanorods in bulk muscle tissues
Serge Grabtchak, Logan G Montgomery, Bo Pang, Yi Wang, Chao Zhang, Zhiyuan Li, Younan Xia & William M Whelan
Pages: 1307-1320
Published online: 13 Feb 2015
AbstractforInterstitial diffuse radiance spectroscopy of gold nanocages and nanorods in bulk muscle tissues | Full Text | References | PDF (6.9 MB)
  • 46 Views
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Article
Synergistic effect of pH-responsive folate-functionalized poloxamer 407-TPGS-mixed micelles on targeted delivery of anticancer drugs
Adeel Masood Butt, Mohd Cairul Iqbal Mohd Amin & Haliza Katas
Pages: 1321-1334
Published online: 13 Feb 2015
AbstractforSynergistic effect of pH-responsive folate-functionalized poloxamer 407-TPGS-mixed micelles on targeted delivery of anticancer drugs | Full Text | References | PDF (2.8 MB)
  • 212 Views
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Article
Differential nanoreprotoxicity of silver nanoparticles in male somatic cells and spermatogonial stem cells
Xi-Feng Zhang, Yun-Jung Choi, Jae Woong Han, Eunsu Kim, Jung Hyun Park, Sangiliyandi Gurunathan & Jin-Hoi Kim
Pages: 1335-1357
Published online: 16 Feb 2015
AbstractforDifferential nanoreprotoxicity of silver nanoparticles in male somatic cells and spermatogonial stem cells | Full Text | References | PDF (5.8 MB)
  • 85 Views
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Article
Binding of plasma proteins to titanium dioxide nanotubes with different diameters
Mukta Kulkarni, Ajda Flašker, Maruša Lokar, Katjuša Mrak-Poljšak, Anca Mazare, Andrej Artenjak, Saša Čučnik, Slavko Kralj, Aljaž Velikonja, Patrik Schmuki, Veronika Kralj-Iglič, Snezna Sodin-Semrl & Aleš Iglič
Pages: 1359-1373
Published online: 18 Feb 2015
AbstractforBinding of plasma proteins to titanium dioxide nanotubes with different diameters | Full Text | References | PDF (3.6 MB)
  • 128 Views
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Article
Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for siRNA targeting HIF-1α for nasopharyngeal carcinoma therapy
Yuhan Chen, Gang Xu, Yi Zheng, Maosheng Yan, Zihuang Li, Yayan Zhou, Lin Mei & Xianming Li
Pages: 1375-1386
Published online: 17 Feb 2015
AbstractforNanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for siRNA targeting HIF-1α for nasopharyngeal carcinoma therapy | Full Text | References | PDF (4.3 MB)
  • 60 Views
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Article
Preparation and in vitro antitumor effects of cytosine arabinoside-loaded genipin-poly-l-glutamic acid-modified bacterial magnetosomes
Yuan-Gang Liu, Qing-Lei Dai, Shi-Bin Wang, Qiong-Jia Deng, Wen-Guo Wu & Ai-Zheng Chen
Pages: 1387-1397
Published online: 17 Feb 2015
AbstractforPreparation and in vitro antitumor effects of cytosine arabinoside-loaded genipin-poly-l-glutamic acid-modified bacterial magnetosomes | Full Text | References | PDF (6.9 MB)
  • 54 Views
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Review

Review Article
Toward a magic or imaginary bullet? Ligands for drug targeting to cancer cells: principles, hopes, and challenges
Monika Toporkiewicz, Justyna Meissner, Lucyna Matusewicz, Aleksander Czogalla & Aleksander F Sikorski
Pages: 1399-1414
Published online: 17 Feb 2015
AbstractforToward a magic or imaginary bullet? Ligands for drug targeting to cancer cells: principles, hopes, and challenges | Full Text | References | PDF (1.1 MB)
  • 131 Views
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Original Research

Article
Antifungal efficacy of itraconazole-loaded TPGS-b-(PCL-ran-PGA) nanoparticles
Lixin Qiu, Bicheng Hu, Hongbo Chen, Shanshan Li, Yuqian Hu, Yi Zheng & Xinxing Wu
Pages: 1415-1423
Published online: 27 Feb 2023
AbstractforAntifungal efficacy of itraconazole-loaded TPGS-b-(PCL-ran-PGA) nanoparticles | Full Text | References | PDF (1.9 MB)
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Open Access
Article
Effect of surface roughness on osteogenesis in vitro and osseointegration in vivo of carbon fiber-reinforced polyetheretherketone–nanohydroxyapatite composite
Yi Deng, Xiaochen Liu, Anxiu Xu, Lixin Wang, Zuyuan Luo, Yunfei Zheng, Feng Deng, Jie Wei, Zhihui Tang & Shicheng Wei
Pages: 1425-1447
Published online: 17 Feb 2015
AbstractforEffect of surface roughness on osteogenesis in vitro and osseointegration in vivo of carbon fiber-reinforced polyetheretherketone–nanohydroxyapatite composite | Full Text | References | PDF (12.5 MB)
  • 263 Views
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Open Access
Article
Cell type-specific response to high intracellular loading of polyacrylic acid-coated magnetic nanoparticles
Jasna Lojk, Vladimir B Bregar, Maruša Rajh, Katarina Miš, Mateja Erdani Kreft, Sergej Pirkmajer, Peter Veranič & Mojca Pavlin
Pages: 1449-1462
Published online: 18 Feb 2015
AbstractforCell type-specific response to high intracellular loading of polyacrylic acid-coated magnetic nanoparticles | Full Text | References | PDF (7.2 MB)
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Open Access
Article
Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling
Caixia Guo, Yinye Xia, Piye Niu, Lizhen Jiang, Junchao Duan, Yang Yu, Xianqing Zhou, Yanbo Li & Zhiwei Sun
Pages: 1463-1477
Published online: 20 Feb 2015
AbstractforSilica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling | Full Text | References | PDF (2.8 MB)
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Open Access
Article
Internalization and fate of silica nanoparticles in C2C12 skeletal muscle cells: evidence of a beneficial effect on myoblast fusion
Sylvie Poussard, Marion Decossas, Olivier Le Bihan, Stéphane Mornet, Grégoire Naudin & Olivier Lambert
Pages: 1479-1492
Published online: 19 Feb 2015
AbstractforInternalization and fate of silica nanoparticles in C2C12 skeletal muscle cells: evidence of a beneficial effect on myoblast fusion | Full Text | References | PDF (10.2 MB)
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Open Access
Article
Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice
Paula Melariri, Lonji Kalombo, Patric Nkuna, Admire Dube, Rose Hayeshi, Benhards Ogutu, Liezl Gibhard, Carmen deKock, Peter Smith, Lubbe Wiesner & Hulda Swai
Pages: 1493-1503
Published online: 20 Feb 2015
AbstractforOral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice | Full Text | References | PDF (592.6 KB)
  • 113 Views
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Open Access
Article
Exceedingly biocompatible and thin-layered reduced graphene oxide nanosheets using an eco-friendly mushroom extract strategy
Kasturi Muthoosamy, Renu Geetha Bai, Ibrahim Babangida Abubakar, Surya Mudavasseril Sudheer, Hong Ngee Lim, Hwei-San Loh, Nay Ming Huang, Chin Hua Chia & Sivakumar Manickam
Pages: 1505-1519
Published online: 20 Feb 2015
AbstractforExceedingly biocompatible and thin-layered reduced graphene oxide nanosheets using an eco-friendly mushroom extract strategy | Full Text | References | PDF (2.5 MB)
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Open Access
Article
Analyses of protein corona on bare and silica-coated gold nanorods against four mammalian cells
Minakshi Das, Dong Kee Yi & Seong Soo A An
Pages: 1521-1545
Published online: 20 Feb 2015
AbstractforAnalyses of protein corona on bare and silica-coated gold nanorods against four mammalian cells | Full Text | References | PDF (4 MB)
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Open Access
Article
Uptake of bright fluorophore core-silica shell nanoparticles by biological systems
Andrew Zane, Christie McCracken, Deborah A Knight, Tanya Young, Anthony D Lutton, John W Olesik, W James Waldman & Prabir K Dutta
Pages: 1547-1567
Published online: 20 Feb 2015
AbstractforUptake of bright fluorophore core-silica shell nanoparticles by biological systems | Full Text | References | PDF (6.9 MB)
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Open Access
Article
Layered nanoemulsions as mucoadhesive buccal systems for controlled delivery of oral cancer therapeutics
Amy Gavin, Jimmy TH Pham, Dawei Wang, Bill Brownlow & Tamer A Elbayoumi
Pages: 1569-1584
Published online: 23 Feb 2015
AbstractforLayered nanoemulsions as mucoadhesive buccal systems for controlled delivery of oral cancer therapeutics | Full Text | References | PDF (2.9 MB)
  • 137 Views
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Open Access
Article
In vitro and in vivo effects of graphene oxide and reduced graphene oxide on glioblastoma
Sławomir Jaworski, Ewa Sawosz, Marta Kutwin, Mateusz Wierzbicki, Mateusz Hinzmann, Marta Grodzik, Anna Winnicka, Ludwika Lipińska, Karolina Włodyga & Andrè Chwalibog
Pages: 1585-1596
Published online: 25 Feb 2015
AbstractforIn vitro and in vivo effects of graphene oxide and reduced graphene oxide on glioblastoma | Full Text | References | PDF (6.5 MB)
  • 207 Views
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Open Access
Article
Detection of hepatitis C virus core protein in serum by atomic force microscopy combined with mass spectrometry
Yuri D Ivanov, Anna L Kaysheva, Pavel A Frantsuzov, Tatyana O Pleshakova, Nikolay V Krohin, Alexander A Izotov, Ivan D Shumov, Vasiliy F Uchaikin, Vladimir A Konev, Vadim S Ziborov & Alexander I Archakov
Pages: 1597-1608
Published online: 25 Feb 2015
AbstractforDetection of hepatitis C virus core protein in serum by atomic force microscopy combined with mass spectrometry | Full Text | References | PDF (3 MB)
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Open Access
Article
Temperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3: in vitro studies
Reihaneh Haghniaz, Rinku D Umrani & Kishore M Paknikar
Pages: 1609-1623
Published online: 25 Feb 2015
AbstractforTemperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3: in vitro studies | Full Text | References | PDF (5.1 MB)
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Open Access
Article
Mixed nanomicelles as potential carriers for systemic delivery of Z-GP-Dox, an FAPα-based doxorubicin prodrug: formulation and pharmacokinetic evaluation
Yuchen Zhang, Xingwang Zhang, Hongming Liu, Shaohui Cai & Baojian Wu
Pages: 1625-1636
Published online: 26 Feb 2015
AbstractforMixed nanomicelles as potential carriers for systemic delivery of Z-GP-Dox, an FAPα-based doxorubicin prodrug: formulation and pharmacokinetic evaluation | Full Text | References | PDF (4.4 MB)
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Open Access
Article
Calcium-activated gene transfection from DNA/poly(amic acid-co-imide) complexes
Szu-Yuan Wu, Li-Ting Chang, Sydeny Peng & Hsieh-Chih Tsai
Pages: 1637-1647
Published online: 27 Feb 2015
AbstractforCalcium-activated gene transfection from DNA/poly(amic acid-co-imide) complexes | Full Text | References | PDF (1.8 MB)
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Open Access
Article
RETRACTED ARTICLE: Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model
Heshu Sulaiman Rahman, Abdullah Rasedee, Chee Wun How, Nazariah Allaudin Zeenathul, Max Stanley Chartrand, Swee Keong Yeap, Ahmad Bustamam Abdul, Sheau Wei Tan, Hemn Hassan Othman, Zahra Ajdari, Farideh Namvar, Palanisamy Arulselvan, Sharida Fakurazi, Parvaneh Mehrbod, Nasibeh Daneshvar & Hasina Begum
Pages: 1649-1666
Published online: 02 Mar 2015
AbstractforRETRACTED ARTICLE: Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model | PDF (8.7 MB)
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Open Access
Article
An efficient method for in vitro gene delivery via regulation of cellular endocytosis pathway
Jing Luo, Caixia Li, Jianlin Chen, Gang Wang, Rong Gao & Zhongwei Gu
Pages: 1667-1678
Published online: 02 Mar 2015
AbstractforAn efficient method for in vitro gene delivery via regulation of cellular endocytosis pathway | Full Text | References | PDF (5.5 MB)
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Open Access
Article
Magnetic resonance hypointensive signal primarily originates from extracellular iron particles in the long-term tracking of mesenchymal stem cells transplanted in the infarcted myocardium
Zheyong Huang, Chenguang Li, Shan Yang, Jianfeng Xu, Yunli Shen, Xinxing Xie, Yuxiang Dai, Hao Lu, Hui Gong, Aijun Sun, Juying Qian & Junbo Ge
Pages: 1679-1690
Published online: 27 Feb 2023
AbstractforMagnetic resonance hypointensive signal primarily originates from extracellular iron particles in the long-term tracking of mesenchymal stem cells transplanted in the infarcted myocardium | Full Text | References | PDF (7.2 MB)
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Open Access
Article
Development of an oral push–pull osmotic pump of fenofibrate-loaded mesoporous silica nanoparticles
Zongzhe Zhao, Chao Wu, Ying Zhao, Yanna Hao, Ying Liu & Wenming Zhao
Pages: 1691-1701
Published online: 03 Mar 2015
AbstractforDevelopment of an oral push–pull osmotic pump of fenofibrate-loaded mesoporous silica nanoparticles | Full Text | References | PDF (2.8 MB)
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Open Access
Article
Blood–brain barrier transport studies, aggregation, and molecular dynamics simulation of multiwalled carbon nanotube functionalized with fluorescein isothiocyanate
Sergey Shityakov, Ellaine Salvador, Giorgia Pastorin & Carola Förster
Pages: 1703-1713
Published online: 03 Mar 2015
AbstractforBlood–brain barrier transport studies, aggregation, and molecular dynamics simulation of multiwalled carbon nanotube functionalized with fluorescein isothiocyanate | Full Text | References | PDF (3.4 MB)
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Open Access
Article
Mesoporous calcium–silicon xerogels with mesopore size and pore volume influence hMSC behaviors by load and sustained release of rhBMP-2
Wenhua Song, Xiangde Li, Jun Qian, Guoyu Lv, Yonggang Yan, Jiacan Su & Jie Wei
Pages: 1715-1726
Published online: 04 Mar 2015
AbstractforMesoporous calcium–silicon xerogels with mesopore size and pore volume influence hMSC behaviors by load and sustained release of rhBMP-2 | Full Text | References | PDF (4.8 MB)
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Open Access

Review

Review Article
Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents
Joan Estelrich, María Jesús Sánchez-Martín & Maria Antònia Busquets
Pages: 1727-1741
Published online: 27 Feb 2023
AbstractforNanoparticles in magnetic resonance imaging: from simple to dual contrast agents | Full Text | References | PDF (1.2 MB)
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Open Access

Original Research

Article
Specifically targeted delivery of protein to phagocytic macrophages
Min Yu, Zeming Chen, Wenjun Guo, Jin Wang, Yupeng Feng, Xiuqi Kong & Zhangyong Hong
Pages: 1743-1757
Published online: 04 Mar 2015
AbstractforSpecifically targeted delivery of protein to phagocytic macrophages | Full Text | References | PDF (3.9 MB)
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Open Access
Article
Quantum dot-based multiplexed imaging in malignant ascites: a new model for malignant ascites classification
Wei-Juan Zeng, Chun-Wei Peng, Jing-Ping Yuan, Ran Cui & Yan Li
Pages: 1759-1768
Published online: 05 Mar 2015
AbstractforQuantum dot-based multiplexed imaging in malignant ascites: a new model for malignant ascites classification | Full Text | References | PDF (6.3 MB)
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Open Access
Article
Self-assembled amphotericin B-loaded polyglutamic acid nanoparticles: preparation, characterization and in vitro potential against Candida albicans
Qamar Zia, Aijaz Ahmed Khan, Zubair Swaleha & Mohammad Owais
Pages: 1769-1790
Published online: 27 Feb 2023
AbstractforSelf-assembled amphotericin B-loaded polyglutamic acid nanoparticles: preparation, characterization and in vitro potential against Candida albicans | Full Text | References | PDF (5.4 MB)
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Open Access
Article
Poly(ethylene glycol)-block-poly(ε-caprolactone)–and phospholipid-based stealth nanoparticles with enhanced therapeutic efficacy on murine breast cancer by improved intracellular drug delivery
Xiaodan He, Li Li, Hong Su, Dinglun Zhou, Hongmei Song, Ling Wang & Xuehua Jiang
Pages: 1791-1804
Published online: 05 Mar 2015
AbstractforPoly(ethylene glycol)-block-poly(ε-caprolactone)–and phospholipid-based stealth nanoparticles with enhanced therapeutic efficacy on murine breast cancer by improved intracellular drug delivery | Full Text | References | PDF (3 MB)
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Open Access
Article
Glioma-targeting micelles for optical/magnetic resonance dual-mode imaging
Qing Zhou, Ketao Mu, Lingyu Jiang, Hui Xie, Wei Liu, Zhengzheng Li, Hui Qi, Shuyan Liang, Huibi Xu, Yanhong Zhu, Wenzhen Zhu & Xiangliang Yang
Pages: 1805-1818
Published online: 05 Mar 2015
AbstractforGlioma-targeting micelles for optical/magnetic resonance dual-mode imaging | Full Text | References | PDF (6.1 MB)
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Open Access
Article
Enhanced oral bioavailability of fenofibrate using polymeric nanoparticulated systems: physicochemical characterization and in vivo investigation
Abid Mehmood Yousaf, Dong Wuk Kim, Yu-Kyoung Oh, Chul Soon Yong, Jong Oh Kim & Han-Gon Choi
Pages: 1819-1830
Published online: 05 Mar 2015
AbstractforEnhanced oral bioavailability of fenofibrate using polymeric nanoparticulated systems: physicochemical characterization and in vivo investigation | Full Text | References | PDF (2.7 MB)
  • 153 Views
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Open Access
Article
SERS-based quantitative detection of ovarian cancer prognostic factor haptoglobin
Jayakumar Perumal, Ghayathri Balasundaram, Aniza P Mahyuddin, Mahesh Choolani & Malini Olivo
Pages: 1831-1840
Published online: 06 Mar 2015
AbstractforSERS-based quantitative detection of ovarian cancer prognostic factor haptoglobin | Full Text | References | PDF (2.1 MB)
  • 159 Views
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Open Access
Article
Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells
Kunwoo Lee, Pengzhi Yu, Nithya Lingampalli, Hyun Jin Kim, Richard Tang & Niren Murthy
Pages: 1841-1854
Published online: 27 Feb 2023
AbstractforPeptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells | Full Text | References | PDF (4.2 MB)
  • 136 Views
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Open Access
Article
Single peptide ligand-functionalized uniform hollow mesoporous silica nanoparticles achieving dual-targeting drug delivery to tumor cells and angiogenic blood vessel cells
Yang Liu, Qing Chen, Ming Xu, Guannan Guan, Wen Hu, Ying Liang, Xiuli Zhao, Mingxi Qiao, Dawei Chen & Hao Liu
Pages: 1855-1867
Published online: 06 Mar 2015
AbstractforSingle peptide ligand-functionalized uniform hollow mesoporous silica nanoparticles achieving dual-targeting drug delivery to tumor cells and angiogenic blood vessel cells | Full Text | References | PDF (2.2 MB)
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Open Access
Article
Accessing to the minor proteome of red blood cells through the influence of the nanoparticle surface properties on the corona composition
Affif Zaccaria, Florence Roux-Dalvai, Ali Bouamrani, Adrien Mombrun, Pascal Mossuz, Bernard Monsarrat & François Berger
Pages: 1869-1883
Published online: 09 Mar 2015
AbstractforAccessing to the minor proteome of red blood cells through the influence of the nanoparticle surface properties on the corona composition | Full Text | References | PDF (1,021.6 KB)
  • 52 Views
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Open Access
Article
Peptide gH625 enters into neuron and astrocyte cell lines and crosses the blood–brain barrier in rats
Salvatore Valiante, Annarita Falanga, Luisa Cigliano, Giuseppina Iachetta, Rosa Anna Busiello, Valeria La Marca, Massimiliano Galdiero, Assunta Lombardi & Stefania Galdiero
Pages: 1885-1898
Published online: 27 Feb 2023
AbstractforPeptide gH625 enters into neuron and astrocyte cell lines and crosses the blood–brain barrier in rats | Full Text | References | PDF (4.5 MB)
  • 117 Views
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Open Access
Article
In vitro percutaneous penetration and characterization of silver from silver-containing textiles
Carlotta Bianco, Sanja Kezic, Matteo Crosera, Vesna Svetličić, Suzana Šegota, Giovanni Maina, Canzio Romano, Francesca Larese & Gianpiero Adami
Pages: 1899-1908
Published online: 10 Mar 2015
AbstractforIn vitro percutaneous penetration and characterization of silver from silver-containing textiles | Full Text | References | PDF (2.5 MB)
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Open Access
Article
Efficient delivery of ursolic acid by poly(N-vinylpyrrolidone)-block-poly (ε-caprolactone) nanoparticles for inhibiting the growth of hepatocellular carcinoma in vitro and in vivo
Hao Zhang, Donghui Zheng, Jing Ding, Huae Xu, Xiaolin Li & Weihao Sun
Pages: 1909-1920
Published online: 27 Feb 2023
AbstractforEfficient delivery of ursolic acid by poly(N-vinylpyrrolidone)-block-poly (ε-caprolactone) nanoparticles for inhibiting the growth of hepatocellular carcinoma in vitro and in vivo | Full Text | References | PDF (4.3 MB)
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Open Access
Article
Therapeutic antitumor efficacy of tumor-derived autophagosome (DRibble) vaccine on head and neck cancer
Hang Su, Qiong Luo, Hao Xie, Xiaofeng Huang, Yanhong Ni, Yongbin Mou & Qingang Hu
Pages: 1921-1930
Published online: 27 Feb 2023
AbstractforTherapeutic antitumor efficacy of tumor-derived autophagosome (DRibble) vaccine on head and neck cancer | Full Text | References | PDF (3.2 MB)
  • 59 Views
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Open Access
Article
Magnetic thermoablation stimuli alter BCL2 and FGF-R1 but not HSP70 expression profiles in BT474 breast tumors
Marcus Stapf, Nadine Pömpner, Melanie Kettering & Ingrid Hilger
Pages: 1931-1939
Published online: 27 Feb 2023
AbstractforMagnetic thermoablation stimuli alter BCL2 and FGF-R1 but not HSP70 expression profiles in BT474 breast tumors | Full Text | References | PDF (2.7 MB)
  • 46 Views
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Open Access
Article
Preparation of poly(β-L-malic acid)-based charge-conversional nanoconjugates for tumor-specific uptake and cellular delivery
Qing Zhou, Tiehong Yang, Youbei Qiao, Songyan Guo, Lin Zhu & Hong Wu
Pages: 1941-1952
Published online: 27 Feb 2023
AbstractforPreparation of poly(β-L-malic acid)-based charge-conversional nanoconjugates for tumor-specific uptake and cellular delivery | Full Text | References | PDF (2.4 MB)
  • 56 Views
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Open Access
Article
Photothermal killing of Staphylococcus aureus using antibody-targeted gold nanoparticles
Nancy J Millenbaugh, Jonathan B Baskin, Mauris N DeSilva, W Rowe Elliott & Randolph D Glickman
Pages: 1953-1960
Published online: 18 Mar 2015
AbstractforPhotothermal killing of Staphylococcus aureus using antibody-targeted gold nanoparticles | Full Text | References | PDF (1.6 MB)
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Open Access
Article
Anticoccidial and antioxidant activities of zinc oxide nanoparticles on Eimeria papillata-induced infection in the jejunum
Mohamed A Dkhil, Saleh Al-Quraishy & Rizwan Wahab
Pages: 1961-1968
Published online: 11 Mar 2015
AbstractforAnticoccidial and antioxidant activities of zinc oxide nanoparticles on Eimeria papillata-induced infection in the jejunum | Full Text | References | PDF (4 MB)
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Open Access
Article
Phase II trial of weekly nab-paclitaxel and carboplatin treatment with or without trastuzumab as nonanthracycline neoadjuvant chemotherapy for locally advanced breast cancer
Liang Huang, Sheng Chen, Ling Yao, Guangyu Liu, Jiong Wu & Zhiming Shao
Pages: 1969-1975
Published online: 11 Mar 2015
AbstractforPhase II trial of weekly nab-paclitaxel and carboplatin treatment with or without trastuzumab as nonanthracycline neoadjuvant chemotherapy for locally advanced breast cancer | Full Text | References | PDF (298.7 KB)
  • 60 Views
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Article
Sunroot mediated synthesis and characterization of silver nanoparticles and evaluation of its antibacterial and rat splenocyte cytotoxic effects
Adithan Aravinthan, Muthusamy Govarthanan, Kandasamy Selvam, Loganathan Praburaman, Thangasamy Selvankumar, Rangachari Balamurugan, Seralathan Kamala-Kannan & Jong-Hoon Kim
Pages: 1977-1983
Published online: 11 Mar 2015
AbstractforSunroot mediated synthesis and characterization of silver nanoparticles and evaluation of its antibacterial and rat splenocyte cytotoxic effects | Full Text | References | PDF (2 MB)
  • 170 Views
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Article
Oxcarbazepine-loaded polymeric nanoparticles: development and permeability studies across in vitro models of the blood–brain barrier and human placental trophoblast
Antonio Lopalco, Hazem Ali, Nunzio Denora & Erik Rytting
Pages: 1985-1996
Published online: 11 Mar 2015
AbstractforOxcarbazepine-loaded polymeric nanoparticles: development and permeability studies across in vitro models of the blood–brain barrier and human placental trophoblast | Full Text | References | PDF (3.1 MB)
  • 148 Views
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Article
RETRACTED ARTICLE: Optimizing stem cell functions and antibacterial properties of TiO2 nanotubes incorporated with ZnO nanoparticles: experiments and modeling
Wenwen Liu, Penglei Su, Arthur Gonzales III, Su Chen, Na Wang, Jinshu Wang, Hongyi Li, Zhenting Zhang & Thomas J Webster
Pages: 1997-2019
Published online: 12 Mar 2015
AbstractforRETRACTED ARTICLE: Optimizing stem cell functions and antibacterial properties of TiO2 nanotubes incorporated with ZnO nanoparticles: experiments and modeling | PDF (25.2 MB)
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Open Access

Methodology

Article
Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast
Francisco G Ortega, Martín A Fernández-Baldo, Jorge G Fernández, María J Serrano, María I Sanz, Juan J Diaz-Mochón, José A Lorente & Julio Raba
Pages: 2021-2031
Published online: 16 Mar 2015
AbstractforStudy of antitumor activity in breast cell lines using silver nanoparticles produced by yeast | Full Text | References | PDF (2.6 MB)
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Open Access

Original Research

Article
New findings about iron oxide nanoparticles and their different effects on murine primary brain cells
Jenni Neubert, Susanne Wagner, Jürgen Kiwit, Anja U Bräuer & Jana Glumm
Pages: 2033-2049
Published online: 13 Mar 2015
AbstractforNew findings about iron oxide nanoparticles and their different effects on murine primary brain cells | Full Text | References | PDF (3.5 MB)
  • 72 Views
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Open Access
Article
Enhancing the anti-colon cancer activity of quercetin by self-assembled micelles
Guangya Xu, Huashan Shi, Laibin Ren, Hongfeng Gou, Daoyin Gong, Xiang Gao & Ning Huang
Pages: 2051-2063
Published online: 16 Mar 2015
AbstractforEnhancing the anti-colon cancer activity of quercetin by self-assembled micelles | Full Text | References | PDF (4.3 MB)
  • 183 Views
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Open Access
Article
Treating cancer stem cells and cancer metastasis using glucose-coated gold nanoparticles
Chenxia Hu, Martin Niestroj, Daniel Yuan, Steven Chang & Jie Chen
Pages: 2065-2077
Published online: 16 Mar 2015
AbstractforTreating cancer stem cells and cancer metastasis using glucose-coated gold nanoparticles | Full Text | References | PDF (1.9 MB)
  • 199 Views
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Open Access
Article
Hydroxypropylcellulose as a novel green reservoir for the synthesis, stabilization, and storage of silver nanoparticles
Muhammad Ajaz Hussain, Abdullah Shah, Ibrahim Jantan, Muhammad Raza Shah, Muhammad Nawaz Tahir, Riaz Ahmad & Syed Nasir Abbas Bukhari
Pages: 2079-2088
Published online: 27 Feb 2023
AbstractforHydroxypropylcellulose as a novel green reservoir for the synthesis, stabilization, and storage of silver nanoparticles | Full Text | References | PDF (5.7 MB)
  • 89 Views
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Open Access
Article
Electrospun gelatin/polycaprolactone nanofibrous membranes combined with a coculture of bone marrow stromal cells and chondrocytes for cartilage engineering
Xiaomin He, Bei Feng, Chuanpei Huang, Hao Wang, Yang Ge, Renjie Hu, Meng Yin, Zhiwei Xu, Wei Wang, Wei Fu & Jinghao Zheng
Pages: 2089-2099
Published online: 17 Mar 2015
AbstractforElectrospun gelatin/polycaprolactone nanofibrous membranes combined with a coculture of bone marrow stromal cells and chondrocytes for cartilage engineering | Full Text | References | PDF (4.7 MB)
  • 103 Views
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Open Access
Article
Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery
Linhua Zhang, Dunwan Zhu, Xia Dong, Hongfan Sun, Cunxian Song, Chun Wang & Deling Kong
Pages: 2101-2114
Published online: 16 Mar 2015
AbstractforFolate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery | Full Text | References | PDF (4.7 MB)
  • 339 Views
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Open Access
Article
A new strategy for specific imaging of neural cells based on peptide-conjugated gold nanoclusters
Enqi Zhang & Ailing Fu
Pages: 2115-2124
Published online: 16 Mar 2015
AbstractforA new strategy for specific imaging of neural cells based on peptide-conjugated gold nanoclusters | Full Text | References | PDF (3.6 MB)
  • 81 Views
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Open Access
Article
The acceptability of nanocarriers for drug delivery in different contexts of use: perceptions of researchers and research trainees in the field of new technologies
Vanessa Chenel, Patrick Boissy, Marie-Sol Poirier, Jean-Pierre Cloarec & Johane Patenaude
Pages: 2125-2139
Published online: 16 Mar 2015
AbstractforThe acceptability of nanocarriers for drug delivery in different contexts of use: perceptions of researchers and research trainees in the field of new technologies | Full Text | References | PDF (751.8 KB)
  • 55 Views
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Open Access
Article
Non-chemotoxic induction of cancer cell death using magnetic nanowires
Maria F Contreras, Rachid Sougrat, Amir Zaher, Timothy Ravasi & Jürgen Kosel
Pages: 2141-2153
Published online: 17 Mar 2015
AbstractforNon-chemotoxic induction of cancer cell death using magnetic nanowires | Full Text | References | PDF (4.1 MB)
  • 72 Views
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Open Access
Article
Facile biofunctionalization of silver nanoparticles for enhanced antibacterial properties, endotoxin removal, and biofilm control
Paramesh Ramulu Lambadi, Tarun Kumar Sharma, Piyush Kumar, Priyanka Vasnani, Sitaramanjaneya Mouli Thalluri, Neha Bisht, Ranjana Pathania & Naveen Kumar Navani
Pages: 2155-2171
Published online: 18 Mar 2015
AbstractforFacile biofunctionalization of silver nanoparticles for enhanced antibacterial properties, endotoxin removal, and biofilm control | Full Text | References | PDF (7.4 MB)
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Article
Targeted delivery of polyamidoamine-paclitaxel conjugate functionalized with anti-human epidermal growth factor receptor 2 trastuzumab
Pengkai Ma, Xuemei Zhang, Ling Ni, Jinming Li, Fengpu Zhang, Zheng Wang, Shengnan Lian & Kaoxiang Sun
Pages: 2173-2190
Published online: 18 Mar 2015
AbstractforTargeted delivery of polyamidoamine-paclitaxel conjugate functionalized with anti-human epidermal growth factor receptor 2 trastuzumab | Full Text | References | PDF (5.7 MB)
  • 90 Views
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Review

Review Article
Parameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructures
Karmani Murugan, Yahya E Choonara, Pradeep Kumar, Divya Bijukumar, Lisa C du Toit & Viness Pillay
Pages: 2191-2206
Published online: 18 Mar 2015
AbstractforParameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructures | Full Text | References | PDF (2.1 MB)
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Original Research

Article
Novel PLGA-based nanoparticles for the oral delivery of insulin
Sampath Malathi, Perumal Nandhakumar, Velayudham Pandiyan, Thomas J Webster & Sengottuvelan Balasubramanian
Pages: 2207-2218
Published online: 19 Mar 2015
AbstractforNovel PLGA-based nanoparticles for the oral delivery of insulin | Full Text | References | PDF (2 MB)
  • 204 Views
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Article
Sensitive electrochemical immunosensor based on three-dimensional nanostructure gold electrode
Guangxian Zhong, Ruilong Lan, Wenxin Zhang, Feihuan Fu, Yiming Sun, Huaping Peng, Tianbin Chen, Yishan Cai, Ailin Liu, Jianhua Lin & Xinhua Lin
Pages: 2219-2228
Published online: 27 Feb 2023
AbstractforSensitive electrochemical immunosensor based on three-dimensional nanostructure gold electrode | Full Text | References | PDF (2.9 MB)
  • 67 Views
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Article
The antitumor activity of tumor-homing peptide-modified thermosensitive liposomes containing doxorubicin on MCF-7/ADR: in vitro and in vivo
Chao Wang, Xin Wang, Ting Zhong, Yang Zhao, Wei-Qiang Zhang, Wei Ren, Dan Huang, Shuang Zhang, Yang Guo, Xin Yao, Yi-Qun Tang, Xuan Zhang & Qiang Zhang
Pages: 2229-2248
Published online: 19 Mar 2015
AbstractforThe antitumor activity of tumor-homing peptide-modified thermosensitive liposomes containing doxorubicin on MCF-7/ADR: in vitro and in vivo | Full Text | References | PDF (5.5 MB)
  • 109 Views
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Article
Rescuing compound bioactivity in a secondary cell-based screening by using γ-cyclodextrin as a molecular carrier
Rafael Claveria-Gimeno, Sonia Vega, Valeria Grazu, Jesús M de la Fuente, Angel Lanas, Adrian Velazquez-Campoy & Olga Abian
Pages: 2249-2259
Published online: 19 Mar 2015
AbstractforRescuing compound bioactivity in a secondary cell-based screening by using γ-cyclodextrin as a molecular carrier | Full Text | References | PDF (777.2 KB)
  • 41 Views
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Article
Silica nanoparticles increase human adipose tissue-derived stem cell proliferation through ERK1/2 activation
Ki Joo Kim, Young Ae Joe, Min Kyoung Kim, Su Jin Lee, Yeon Hee Ryu, Dong-Woo Cho & Jong Won Rhie
Pages: 2261-2272
Published online: 24 Mar 2015
AbstractforSilica nanoparticles increase human adipose tissue-derived stem cell proliferation through ERK1/2 activation | Full Text | References | PDF (2.2 MB)
  • 71 Views
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Article
The fate of calcium carbonate nanoparticles administered by oral route: absorption and their interaction with biological matrices
Jeong-A Lee, Mi-Kyung Kim, Hyoung-Mi Kim, Jong Kwon Lee, Jayoung Jeong, Young-Rok Kim, Jae-Min Oh & Soo-Jin Choi
Pages: 2273-2293
Published online: 23 Mar 2015
AbstractforThe fate of calcium carbonate nanoparticles administered by oral route: absorption and their interaction with biological matrices | Full Text | References | PDF (4.8 MB)
  • 160 Views
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Article
Comparison of two self-assembled macromolecular prodrug micelles with different conjugate positions of SN38 for enhancing antitumor activity
Yi Liu, Hongyu Piao, Ying Gao, Caihong Xu, Ye Tian, Lihong Wang, Jinwen Liu, Bo Tang, Meijuan Zou & Gang Cheng
Pages: 2295-2311
Published online: 23 Mar 2015
AbstractforComparison of two self-assembled macromolecular prodrug micelles with different conjugate positions of SN38 for enhancing antitumor activity | Full Text | References | PDF (4.6 MB)
  • 64 Views
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Article
A hybrid substratum for primary hepatocyte culture that enhances hepatic functionality with low serum dependency
Qingyuan Meng, Chunsheng Tao, Zhiye Qiu, Toshihiro Akaike, Fuzhai Cui & Xiumei Wang
Pages: 2313-2323
Published online: 23 Mar 2015
AbstractforA hybrid substratum for primary hepatocyte culture that enhances hepatic functionality with low serum dependency | Full Text | References | PDF (3.5 MB)
  • 46 Views
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Article
Water-soluble l-cysteine-coated FePt nanoparticles as dual MRI/CT imaging contrast agent for glioma
Shuyan Liang, Qing Zhou, Min Wang, Yanhong Zhu, Qingzhi Wu & Xiangliang Yang
Pages: 2325-2333
Published online: 23 Mar 2015
AbstractforWater-soluble l-cysteine-coated FePt nanoparticles as dual MRI/CT imaging contrast agent for glioma | Full Text | References | PDF (2.7 MB)
  • 110 Views
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Article
Chitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion
Wen Song, Xin Song, Chuanxu Yang, Shan Gao, Lasse Hyldgaard Klausen, Yumei Zhang, Mingdong Dong & Jørgen Kjems
Pages: 2335-2346
Published online: 24 Mar 2015
AbstractforChitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion | Full Text | References | PDF (4.6 MB)
  • 76 Views
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Article
Phthalocyanine-loaded graphene nanoplatform for imaging-guided combinatorial phototherapy
Olena Taratula, Mehulkumar Patel, Canan Schumann, Michael A Naleway, Addison J Pang, Huixin He & Oleh Taratula
Pages: 2347-2362
Published online: 24 Mar 2015
AbstractforPhthalocyanine-loaded graphene nanoplatform for imaging-guided combinatorial phototherapy | Full Text | References | PDF (2.9 MB)
  • 91 Views
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Article
Fluoromica nanoparticle cytotoxicity in macrophages decreases with size and extent of uptake
Nicolin Tee, Yingdong Zhu, Gysell M Mortimer, Darren J Martin & Rodney F Minchin
Pages: 2363-2375
Published online: 26 Mar 2015
AbstractforFluoromica nanoparticle cytotoxicity in macrophages decreases with size and extent of uptake | Full Text | References | PDF (4.8 MB)
  • 43 Views
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Article
Mechanism of enhanced antiosteoporosis effect of circinal–icaritin by self-assembled nanomicelles in vivo with suet oil and sodium deoxycholate
Jun Jiang, Jie Li, Zhenhai Zhang, E Sun, Liang Feng & Xiaobin Jia
Pages: 2377-2389
Published online: 27 Feb 2023
AbstractforMechanism of enhanced antiosteoporosis effect of circinal–icaritin by self-assembled nanomicelles in vivo with suet oil and sodium deoxycholate | Full Text | References | PDF (2.7 MB)
  • 63 Views
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Article
Poloxamer-based binary hydrogels for delivering tramadol hydrochloride: sol-gel transition studies, dissolution-release kinetics, in vitro toxicity, and pharmacological evaluation
Ana Claudia Mendonça dos Santos, Alessandra Cristina Santos Akkari, Iasmin Rosanne Silva Ferreira, Cintia Rodrigues Maruyama, Monica Pascoli, Viviane Aparecida Guilherme, Eneida de Paula, Leonardo Fernandes Fraceto, Renata de Lima, Patrícia da Silva Melo & Daniele Ribeiro de Araujo
Pages: 2391-2401
Published online: 25 Mar 2015
AbstractforPoloxamer-based binary hydrogels for delivering tramadol hydrochloride: sol-gel transition studies, dissolution-release kinetics, in vitro toxicity, and pharmacological evaluation | Full Text | References | PDF (707 KB)
  • 176 Views
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Article
Self-nanoemulsifying drug delivery systems ameliorate the oral delivery of silymarin in rats with Roux-en-Y gastric bypass surgery
Chun-Han Chen, Cheng-Chih Chang, Tsung-Hsien Shih, Ibrahim A Aljuffali, Ta-Sen Yeh & Jia-You Fang
Pages: 2403-2416
Published online: 25 Mar 2015
AbstractforSelf-nanoemulsifying drug delivery systems ameliorate the oral delivery of silymarin in rats with Roux-en-Y gastric bypass surgery | Full Text | References | PDF (4.8 MB)
  • 105 Views
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Letter

Letter
Docetaxel-loaded solid lipid nanoparticles as a basis for a targeted and dose-sparing personalized breast cancer treatment strategy
Natalia V Danilova, Zhomart R Kalzhanov, Nina A Nefedova, Pavel G Mal’kov, Ioannis P Kosmas, Marina Y Eliseeva & Ospan A Mynbaev
Pages: 2417-2421
Published online: 25 Mar 2015
First Page PreviewforDocetaxel-loaded solid lipid nanoparticles as a basis for a targeted and dose-sparing personalized breast cancer treatment strategy | Full Text | References | PDF (183.3 KB)
  • 56 Views
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Original Research

Article
Nanoscale TiO2 nanotubes govern the biological behavior of human glioma and osteosarcoma cells
Ang Tian, Xiaofei Qin, Anhua Wu, Hangzhou Zhang, Quan Xu, Deguang Xing, He Yang, Bo Qiu, Xiangxin Xue, Dongyong Zhang & Chenbo Dong
Pages: 2423-2439
Published online: 25 Mar 2015
AbstractforNanoscale TiO2 nanotubes govern the biological behavior of human glioma and osteosarcoma cells | Full Text | References | PDF (11.5 MB)
  • 59 Views
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Article
Alendronate-coated long-circulating liposomes containing 99mtechnetium-ceftizoxime used to identify osteomyelitis
Diego dos Santos Ferreira, Fernanda Alves Boratto, Valbert Nascimento Cardoso, Rogéria Serakides, Simone Odília Fernandes, Lucas Antônio Miranda Ferreira & Mônica Cristina Oliveira
Pages: 2441-2450
Published online: 25 Mar 2015
AbstractforAlendronate-coated long-circulating liposomes containing 99mtechnetium-ceftizoxime used to identify osteomyelitis | Full Text | References | PDF (1.1 MB)
  • 79 Views
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Review

Review Article
Graphene-based nanovehicles for photodynamic medical therapy
Yan Li, Haiqing Dong, Yongyong Li & Donglu Shi
Pages: 2451-2459
Published online: 27 Mar 2015
AbstractforGraphene-based nanovehicles for photodynamic medical therapy | Full Text | References | PDF (1.8 MB)
  • 111 Views
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Original Research

Article
Fabrication of genistein-loaded biodegradable TPGS-b-PCL nanoparticles for improved therapeutic effects in cervical cancer cells
Hongling Zhang, Gan Liu, Xiaowei Zeng, Yanping Wu, Chengming Yang, Lin Mei, Zhongyuan Wang & Laiqiang Huang
Pages: 2461-2473
Published online: 27 Mar 2015
AbstractforFabrication of genistein-loaded biodegradable TPGS-b-PCL nanoparticles for improved therapeutic effects in cervical cancer cells | Full Text | References | PDF (4.3 MB)
  • 127 Views
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Article
Quantitative analysis of total β-subunit of human chorionic gonadotropin concentration in urine by immunomagnetic reduction to assist in the diagnosis of ectopic pregnancy
Chen-Yu Chen, Yuh-Ming Hwu, Chie-Pein Chen & Chia-Chen Chang
Pages: 2475-2483
Published online: 30 Mar 2015
AbstractforQuantitative analysis of total β-subunit of human chorionic gonadotropin concentration in urine by immunomagnetic reduction to assist in the diagnosis of ectopic pregnancy | Full Text | References | PDF (1.2 MB)
  • 62 Views
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Article
Bypassing the EPR effect with a nanomedicine harboring a sustained-release function allows better tumor control
Yao An Shen, Ing Luen Shyu, Maggie Lu, Chun Lin He, Yen Mei Hsu, Hsiang Fa Liang, Chih Peng Liu, Ren Shyan Liu, Biing Jiun Shen, Yau Huei Wei & Chi Mu Chuang
Pages: 2485-2502
Published online: 30 Mar 2015
AbstractforBypassing the EPR effect with a nanomedicine harboring a sustained-release function allows better tumor control | Full Text | References | PDF (5 MB)
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Editorial

Editorial
Research highlights from the International Journal of Nanomedicine 2014
Sarah H Mian, Neel A Patel, Farina Shah, Sateesh B Arja & Farooq A Shiekh
Pages: 2503-2505
Published online: 31 Mar 2015
First Page PreviewforResearch highlights from the International Journal of Nanomedicine 2014 | Full Text | References | PDF (630 KB)
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Original Research

Article
GEM-loaded magnetic albumin nanospheres modified with cetuximab for simultaneous targeting, magnetic resonance imaging, and double-targeted thermochemotherapy of pancreatic cancer cells
Ling Wang, Yanli An, Chenyan Yuan, Hao Zhang, Chen Liang, Fengan Ding, Qi Gao & Dongsheng Zhang
Pages: 2507-2519
Published online: 30 Mar 2015
AbstractforGEM-loaded magnetic albumin nanospheres modified with cetuximab for simultaneous targeting, magnetic resonance imaging, and double-targeted thermochemotherapy of pancreatic cancer cells | Full Text | References | PDF (3.9 MB)
  • 66 Views
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Article
Elucidating the in vivo fate of nanocrystals using a physiologically based pharmacokinetic model: a case study with the anticancer agent SNX-2112
Dong Dong, Xiao Wang, Huailing Wang, Xingwang Zhang, Yifei Wang & Baojian Wu
Pages: 2521-2535
Published online: 31 Mar 2015
AbstractforElucidating the in vivo fate of nanocrystals using a physiologically based pharmacokinetic model: a case study with the anticancer agent SNX-2112 | Full Text | References | PDF (2.2 MB)
  • 73 Views
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Article
Poly(lactic-co-glycolic acid) nanoparticles conjugated with CD133 aptamers for targeted salinomycin delivery to CD133+ osteosarcoma cancer stem cells
Miaozhong Ni, Min Xiong, Xinchao Zhang, Guoping Cai, Huaiwen Chen, Qingmin Zeng & Zuochong Yu
Pages: 2537-2554
Published online: 31 Mar 2015
AbstractforPoly(lactic-co-glycolic acid) nanoparticles conjugated with CD133 aptamers for targeted salinomycin delivery to CD133+ osteosarcoma cancer stem cells | Full Text | References | PDF (3.9 MB)
  • 99 Views
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Article
Angiogenesis and bone regeneration of porous nano-hydroxyapatite/coralline blocks coated with rhVEGF165 in critical-size alveolar bone defects in vivo
Bing Du, Weizhen Liu, Yue Deng, Shaobing Li, Xiangning Liu, Yan Gao & Lei Zhou
Pages: 2555-2565
Published online: 31 Mar 2015
AbstractforAngiogenesis and bone regeneration of porous nano-hydroxyapatite/coralline blocks coated with rhVEGF165 in critical-size alveolar bone defects in vivo | Full Text | References | PDF (8.3 MB)
  • 87 Views
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Article
Biosynthesis, characterization, and antimicrobial applications of silver nanoparticles
Priyanka Singh, Yeon Ju Kim, Hina Singh, Chao Wang, Kyu Hyon Hwang, Mohamed El-Agamy Farh & Deok Chun Yang
Pages: 2567-2577
Published online: 31 Mar 2015
AbstractforBiosynthesis, characterization, and antimicrobial applications of silver nanoparticles | Full Text | References | PDF (4.4 MB)
  • 928 Views
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Article
Highly effective antiangiogenesis via magnetic mesoporous silica-based siRNA vehicle targeting the VEGF gene for orthotopic ovarian cancer therapy
Yijie Chen, Xinran Wang, Ting Liu, Ding Sheng-zi Zhang, Yunfei Wang, Hongchen Gu & Wen Di
Pages: 2579-2594
Published online: 31 Mar 2015
AbstractforHighly effective antiangiogenesis via magnetic mesoporous silica-based siRNA vehicle targeting the VEGF gene for orthotopic ovarian cancer therapy | Full Text | References | PDF (8.2 MB)
  • 88 Views
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Article
Antibody-mediated targeting of iron oxide nanoparticles to the folate receptor alpha increases tumor cell association in vitro and in vivo
Christian Ndong, Seiko Toraya-Brown, Katsiaryna Kekalo, Ian Baker, Tillman U Gerngross, Steven N Fiering & Karl E Griswold
Pages: 2595-2617
Published online: 01 Apr 2015
AbstractforAntibody-mediated targeting of iron oxide nanoparticles to the folate receptor alpha increases tumor cell association in vitro and in vivo | Full Text | References | PDF (6.9 MB)
  • 100 Views
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Article
Enhanced magnetic resonance imaging and staining of cancer cells using ferrimagnetic H-ferritin nanoparticles with increasing core size
Yao Cai, Changqian Cao, Xiaoqing He, Caiyun Yang, Lanxiang Tian, Rixiang Zhu & Yongxin Pan
Pages: 2619-2634
Published online: 01 Apr 2015
AbstractforEnhanced magnetic resonance imaging and staining of cancer cells using ferrimagnetic H-ferritin nanoparticles with increasing core size | Full Text | References | PDF (7.3 MB)
  • 110 Views
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Article
Significant improvement of biocompatibility of polypropylene mesh for incisional hernia repair by using poly-ε-caprolactone nanofibers functionalized with thrombocyte-rich solution
Martin Plencner, Eva Prosecká, Michala Rampichová, Barbora East, Matej Buzgo, Lucie Vysloužilová, Jiří Hoch & Evžen Amler
Pages: 2635-2646
Published online: 01 Apr 2015
AbstractforSignificant improvement of biocompatibility of polypropylene mesh for incisional hernia repair by using poly-ε-caprolactone nanofibers functionalized with thrombocyte-rich solution | Full Text | References | PDF (2.6 MB)
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Review

Review Article
Role of lipegfilgrastim in the management of chemotherapy-induced neutropenia
Jonathan Hoggatt, Tiffany A Tate & Louis M Pelus
Pages: 2647-2652
Published online: 01 Apr 2015
AbstractforRole of lipegfilgrastim in the management of chemotherapy-induced neutropenia | Full Text | References | PDF (309.9 KB)
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Original Research

Article
Rescuing apoptotic neurons in Alzheimer’s disease using wheat germ agglutinin-conjugated and cardiolipin-conjugated liposomes with encapsulated nerve growth factor and curcumin
Yung-Chih Kuo & Ching-Chun Lin
Pages: 2653-2672
Published online: 01 Apr 2015
AbstractforRescuing apoptotic neurons in Alzheimer’s disease using wheat germ agglutinin-conjugated and cardiolipin-conjugated liposomes with encapsulated nerve growth factor and curcumin | Full Text | References | PDF (7.8 MB)
  • 116 Views
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Article
A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency
Aristides D Tagalakis, Sara Castellaro, Haiyan Zhou, Alison Bienemann, Mustafa M Munye, David McCarthy, Edward A White & Stephen L Hart
Pages: 2673-2683
Published online: 01 Apr 2015
AbstractforA method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency | Full Text | References | PDF (2.3 MB)
  • 66 Views
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Article
Synthesis and anti-fungal effect of silver nanoparticles–chitosan composite particles
Lung-Shuo Wang, Chih-Yu Wang, Chih-Hui Yang, Chen-Ling Hsieh, Szu-Yu Chen, Chi-Yen Shen, Jia-Jung Wang & Keng-Shiang Huang
Pages: 2685-2696
Published online: 01 Apr 2015
AbstractforSynthesis and anti-fungal effect of silver nanoparticles–chitosan composite particles | Full Text | References | PDF (6.1 MB)
  • 279 Views
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Article
High dispersity of carbon nanotubes diminishes immunotoxicity in spleen
Soyoung Lee, Dongwoo Khang & Sang-Hyun Kim
Pages: 2697-2710
Published online: 01 Apr 2015
AbstractforHigh dispersity of carbon nanotubes diminishes immunotoxicity in spleen | Full Text | References | PDF (4 MB)
  • 63 Views
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Article
Colorimetric biosensing of targeted gene sequence using dual nanoparticle platforms
Jeevan Thavanathan, Nay Ming Huang & Kwai Lin Thong
Pages: 2711-2722
Published online: 02 Apr 2015
AbstractforColorimetric biosensing of targeted gene sequence using dual nanoparticle platforms | Full Text | References | PDF (3.6 MB)
  • 48 Views
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Article
CdTe quantum dots induce activation of human platelets: implications for nanoparticle hemocompatibility
Stephen P Samuel, Maria J Santos-Martinez, Carlos Medina, Namrata Jain, Marek W Radomski, Adriele Prina-Mello & Yuri Volkov
Pages: 2723-2734
Published online: 02 Apr 2015
AbstractforCdTe quantum dots induce activation of human platelets: implications for nanoparticle hemocompatibility | Full Text | References | PDF (4 MB)
  • 60 Views
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Article
Efficient delivery of NF-κB siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles
Zhenzhen Liu, Haijun Gong, Rui Zeng, Xuan Liang, Li-Ming Zhang, Liqun Yang & Yuqing Lan
Pages: 2735-2749
Published online: 07 Apr 2015
AbstractforEfficient delivery of NF-κB siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles | Full Text | References | PDF (2.5 MB)
  • 78 Views
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Article
Potential recombinant vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles
Chean Yeah Yong, Swee Keong Yeap, Kok Lian Ho, Abdul Rahman Omar & Wen Siang Tan
Pages: 2751-2763
Published online: 02 Apr 2015
AbstractforPotential recombinant vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles | Full Text | References | PDF (1.5 MB)
  • 129 Views
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Article
The potential of follicle-stimulating hormone peptide-modified triptolide-loaded nanoparticles to induce a mouse model of premature ovarian insufficiency
Xiu-Ying Chen, Wu-Lian Chen, Min Ma, Chao Gu, Xi-Rong Xiao & Bin Li
Pages: 2765-2774
Published online: 07 Apr 2015
AbstractforThe potential of follicle-stimulating hormone peptide-modified triptolide-loaded nanoparticles to induce a mouse model of premature ovarian insufficiency | Full Text | References | PDF (2.2 MB)
  • 80 Views
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Article
Efficacy and feasibility of the immunomagnetic separation based diagnosis for detecting sentinel lymph node metastasis from breast cancer
Xiang-Cheng Zhi, Min Zhang, Ting-Ting Meng, Xiao-Bei Zhang, Zhen-Dong Shi, Yan Liu, Jing-Jing Liu, Sheng Zhang & Jin Zhang
Pages: 2775-2784
Published online: 07 Apr 2015
AbstractforEfficacy and feasibility of the immunomagnetic separation based diagnosis for detecting sentinel lymph node metastasis from breast cancer | Full Text | References | PDF (1.2 MB)
  • 37 Views
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Review

Review Article
Multifaceted prospects of nanocomposites for cardiovascular grafts and stents
Muthu Vignesh Vellayappan, Arunpandian Balaji, Aruna Priyadarshini Subramanian, Agnes Aruna John, Saravana Kumar Jaganathan, Selvakumar Murugesan, Eko Supriyanto & Mustafa Yusof
Pages: 2785-2803
Published online: 27 Feb 2023
AbstractforMultifaceted prospects of nanocomposites for cardiovascular grafts and stents | Full Text | References | PDF (987.6 KB)
  • 104 Views
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Original Research

Article
Solid and liquid lipid-based binary solid lipid nanoparticles of diacerein: in vitro evaluation of sustained release, simultaneous loading of gold nanoparticles, and potential thermoresponsive behavior
Mubashar Rehman, Asadullah Madni, Ayesha Ihsan, Waheed Samraiz Khan, Muhammad Imran Khan, Muhammad Ahmad Mahmood, Muhammad Ashfaq, Sadia Zafar Bajwa & Imran Shakir
Pages: 2805-2814
Published online: 07 Apr 2015
AbstractforSolid and liquid lipid-based binary solid lipid nanoparticles of diacerein: in vitro evaluation of sustained release, simultaneous loading of gold nanoparticles, and potential thermoresponsive behavior | Full Text | References | PDF (651.6 KB)
  • 193 Views
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Article
Thermal properties and physicochemical behavior in aqueous solution of pyrene-labeled poly(ethylene glycol)-polylactide conjugate
Wei-Lin Chen, Yun-Fen Peng, Sheng-Kuo Chiang & Ming-Hsi Huang
Pages: 2815-2822
Published online: 08 Apr 2015
AbstractforThermal properties and physicochemical behavior in aqueous solution of pyrene-labeled poly(ethylene glycol)-polylactide conjugate | Full Text | References | PDF (882.7 KB)
  • 65 Views
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Article
Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene
Rwei-Fen S Huang, Yi-Jun Wei, Baskaran Stephen Inbaraj & Bing-Huei Chen
Pages: 2823-2846
Published online: 08 Apr 2015
AbstractforInhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene | Full Text | References | PDF (12.2 MB)
  • 195 Views
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Article
Coadministration of doxorubicin and etoposide loaded in camel milk phospholipids liposomes showed increased antitumor activity in a murine model
Hamzah M Maswadeh, Ahmed N Aljarbou, Mohammed S Alorainy, Arshad H Rahmani & Masood A Khan
Pages: 2847-2855
Published online: 13 Apr 2015
AbstractforCoadministration of doxorubicin and etoposide loaded in camel milk phospholipids liposomes showed increased antitumor activity in a murine model | Full Text | References | PDF (1.3 MB)
  • 64 Views
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Article
A novel nanobody specific for respiratory surfactant protein A has potential for lung targeting
Shan-Mei Wang, Xian He, Nan Li, Feng Yu, Yang Hu, Liu-Sheng Wang, Peng Zhang, Yu-Kui Du, Shan-Shan Du, Zhao-Fang Yin, Ya-Ru Wei, Xavier Mulet, Greg Coia, Dong Weng, Jian-Hua He, Min Wu & Hui-Ping Li
Pages: 2857-2869
Published online: 13 Apr 2015
AbstractforA novel nanobody specific for respiratory surfactant protein A has potential for lung targeting | Full Text | References | PDF (6.1 MB)
  • 92 Views
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Article
Using inositol as a biocompatible ligand for efficient transgene expression
Lei Zhang, Susan L Bellis, Yiwen Fan & Yunkun Wu
Pages: 2871-2884
Published online: 13 Apr 2015
AbstractforUsing inositol as a biocompatible ligand for efficient transgene expression | Full Text | References | PDF (5.9 MB)
  • 46 Views
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Article
Inhibition of various gram-positive and gram- negative bacteria growth on selenium nanoparticle coated paper towels
Qi Wang, Philip Larese-Casanova & Thomas J Webster
Pages: 2885-2894
Published online: 27 Feb 2023
AbstractforInhibition of various gram-positive and gram- negative bacteria growth on selenium nanoparticle coated paper towels | Full Text | References | PDF (2.7 MB)
  • 120 Views
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Article
Synthesis, characterization, and immune efficacy of layered double hydroxide@SiO2 nanoparticles with shell-core structure as a delivery carrier for Newcastle disease virus DNA vaccine
Kai Zhao, Guangyu Rong, Chen Guo, Xiaomei Luo, Hong Kang, Yanwei Sun, Chunxiao Dai, Xiaohua Wang, Xin Wang, Zheng Jin, Shangjin Cui & Qingshen Sun
Pages: 2895-2911
Published online: 13 Apr 2015
AbstractforSynthesis, characterization, and immune efficacy of layered double hydroxide@SiO2 nanoparticles with shell-core structure as a delivery carrier for Newcastle disease virus DNA vaccine | Full Text | References | PDF (8.2 MB)
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Article
Polymeric nanoparticle-based delivery of microRNA-199a-3p inhibits proliferation and growth of osteosarcoma cells
Linlin Zhang, Arun K lyer, Xiaoqian Yang, Eisuke Kobayashi, Yuqi Guo, Henry Mankin, Francis J Hornicek, Mansoor M Amiji & Zhenfeng Duan
Pages: 2913-2924
Published online: 15 Apr 2015
AbstractforPolymeric nanoparticle-based delivery of microRNA-199a-3p inhibits proliferation and growth of osteosarcoma cells | Full Text | References | PDF (3.1 MB)
  • 80 Views
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Article
Cu2+-RGDFRGDS: exploring the mechanism and high efficacy of the nanoparticle in antithrombotic therapy
Jianhui Wu, Yuji Wang, Yaonan Wang, Ming Zhao, Xiaoyi Zhang, Lin Gui, Shurui Zhao, Haimei Zhu, Jinghua Zhao & Shiqi Peng
Pages: 2925-2938
Published online: 15 Apr 2015
AbstractforCu2+-RGDFRGDS: exploring the mechanism and high efficacy of the nanoparticle in antithrombotic therapy | Full Text | References | PDF (4.9 MB)
  • 51 Views
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Article
Tungsten oxide-Au nanosized film composites for glucose oxidation and sensing in neutral medium
Maxime Gougis, Dongling Ma & Mohamed Mohamedi
Pages: 2939-2950
Published online: 15 Apr 2015
AbstractforTungsten oxide-Au nanosized film composites for glucose oxidation and sensing in neutral medium | Full Text | References | PDF (3 MB)
  • 56 Views
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Article
Reduction of graphene oxide by resveratrol: a novel and simple biological method for the synthesis of an effective anticancer nanotherapeutic molecule
Sangiliyandi Gurunathan, Jae Woong Han, Eun Su Kim, Jung Hyun Park & Jin-Hoi Kim
Pages: 2951-2969
Published online: 15 Apr 2015
AbstractforReduction of graphene oxide by resveratrol: a novel and simple biological method for the synthesis of an effective anticancer nanotherapeutic molecule | Full Text | References | PDF (3.9 MB)
  • 204 Views
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Article
Chloramphenicol encapsulated in poly-ε-caprolactone–pluronic composite: nanoparticles for treatment of MRSA-infected burn wounds
Sanjeeb Kalita, Banasmita Devi, Raghuram Kandimalla, Kaustav Kalyan Sharma, Arup Sharma, Kasturi Kalita, Amal Chandra Kataki & Jibon Kotoky
Pages: 2971-2984
Published online: 15 Apr 2015
AbstractforChloramphenicol encapsulated in poly-ε-caprolactone–pluronic composite: nanoparticles for treatment of MRSA-infected burn wounds | Full Text | References | PDF (3.4 MB)
  • 139 Views
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Article
Surface modification of MPEG-b-PCL-based nanoparticles via oxidative self-polymerization of dopamine for malignant melanoma therapy
Wei Xiong, Lixia Peng, Hongbo Chen & Qin Li
Pages: 2985-2996
Published online: 27 Feb 2023
AbstractforSurface modification of MPEG-b-PCL-based nanoparticles via oxidative self-polymerization of dopamine for malignant melanoma therapy | Full Text | References | PDF (2.2 MB)
  • 183 Views
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Article
Poly(d,l-lactide-co-glycolide)–chitosan composite particles for the treatment of lung cancer
Neha Arya & Dhirendra S Katti
Pages: 2997-3011
Published online: 16 Apr 2015
AbstractforPoly(d,l-lactide-co-glycolide)–chitosan composite particles for the treatment of lung cancer | Full Text | References | PDF (3.8 MB)
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Review

Review Article
Some inferences from in vivo experiments with metal and metal oxide nanoparticles: the pulmonary phagocytosis response, subchronic systemic toxicity and genotoxicity, regulatory proposals, searching for bioprotectors (a self-overview)
Boris A Katsnelson, Larisa I Privalova, Marina P Sutunkova, Vladimir B Gurvich, Nadezhda V Loginova, Ilzira A Minigalieva, Ekaterina P Kireyeva, Vladimir Y Shur, Ekaterina V Shishkina, Ya B Beikin, Oleg H Makeyev & Irene E Valamina
Pages: 3013-3029
Published online: 16 Apr 2015
AbstractforSome inferences from in vivo experiments with metal and metal oxide nanoparticles: the pulmonary phagocytosis response, subchronic systemic toxicity and genotoxicity, regulatory proposals, searching for bioprotectors (a self-overview) | Full Text | References | PDF (2.6 MB)
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Original Research

Article
Pharmacokinetics of quercetin-loaded nanodroplets with ultrasound activation and their use for bioimaging
Li-Wen Chang, Mei-Ling Hou, Shuo-Hui Hung, Lie-Chwen Lin & Tung-Hu Tsai
Pages: 3031-3042
Published online: 17 Apr 2015
AbstractforPharmacokinetics of quercetin-loaded nanodroplets with ultrasound activation and their use for bioimaging | Full Text | References | PDF (1.4 MB)
  • 86 Views
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Article
CD44+/CD24− breast cancer cells exhibit phenotypic reversion in three-dimensional self-assembling peptide RADA16 nanofiber scaffold
Kun Mi & Zhihua Xing
Pages: 3043-3053
Published online: 20 Apr 2015
AbstractforCD44+/CD24− breast cancer cells exhibit phenotypic reversion in three-dimensional self-assembling peptide RADA16 nanofiber scaffold | Full Text | References | PDF (3.9 MB)
  • 67 Views
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Article
Characterization of nanostructured ureteral stent with gradient degradation in a porcine model
Xiaoqing Wang, Hongli Shan, Jixue Wang, Yuchuan Hou, Jianxun Ding, Qihui Chen, Jingjing Guan, Chunxi Wang & Xuesi Chen
Pages: 3055-3064
Published online: 20 Apr 2015
AbstractforCharacterization of nanostructured ureteral stent with gradient degradation in a porcine model | Full Text | References | PDF (7.9 MB)
  • 88 Views
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Article
Nitric oxide-releasing poly(lactic-co-glycolic acid)-polyethylenimine nanoparticles for prolonged nitric oxide release, antibacterial efficacy, and in vivo wound healing activity
Hasan Nurhasni, Jiafu Cao, Moonjeong Choi, Il Kim, Bok Luel Lee, Yunjin Jung & Jin-Wook Yoo
Pages: 3065-3080
Published online: 22 Apr 2015
AbstractforNitric oxide-releasing poly(lactic-co-glycolic acid)-polyethylenimine nanoparticles for prolonged nitric oxide release, antibacterial efficacy, and in vivo wound healing activity | Full Text | References | PDF (9.7 MB)
  • 320 Views
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Article
Delivery of vincristine sulfate-conjugated gold nanoparticles using liposomes: a light-responsive nanocarrier with enhanced antitumor efficiency
Ying Liu, Man He, Mengmeng Niu, Yiqing Zhao, Yuanzhang Zhu, Zhenhua Li & Nianping Feng
Pages: 3081-3095
Published online: 27 Feb 2023
AbstractforDelivery of vincristine sulfate-conjugated gold nanoparticles using liposomes: a light-responsive nanocarrier with enhanced antitumor efficiency | Full Text | References | PDF (5.5 MB)
  • 118 Views
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Review

Review Article
Magnetic particle imaging: current developments and future directions
Nikolaos Panagiotopoulos, Robert L Duschka, Mandy Ahlborg, Gael Bringout, Christina Debbeler, Matthias Graeser, Christian Kaethner, Kerstin Lüdtke-Buzug, Hanne Medimagh, Jan Stelzner, Thorsten M Buzug, Jörg Barkhausen, Florian M Vogt & Julian Haegele
Pages: 3097-3114
Published online: 27 Feb 2023
AbstractforMagnetic particle imaging: current developments and future directions | Full Text | References | PDF (1.7 MB)
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Original Research

Article
Functional consequences for primary human alveolar macrophages following treatment with long, but not short, multiwalled carbon nanotubes
Sinbad Sweeney, Davide Grandolfo, Pakatip Ruenraroengsak & Teresa D Tetley
Pages: 3115-3129
Published online: 23 Apr 2015
AbstractforFunctional consequences for primary human alveolar macrophages following treatment with long, but not short, multiwalled carbon nanotubes | Full Text | References | PDF (3.2 MB)
  • 61 Views
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Article
Insight into molecular dynamics simulation of BRAF(V600E) and potent novel inhibitors for malignant melanoma
Hsin-Chieh Tang & Yu-Chian Chen
Pages: 3131-3146
Published online: 23 Apr 2015
AbstractforInsight into molecular dynamics simulation of BRAF(V600E) and potent novel inhibitors for malignant melanoma | Full Text | References | PDF (9.6 MB)
  • 125 Views
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Article
Reversal of multidrug resistance in MCF-7/Adr cells by codelivery of doxorubicin and BCL2 siRNA using a folic acid-conjugated polyethylenimine hydroxypropyl-β-cyclodextrin nanocarrier
Jin-Ming Li, Wei Zhang, Hua Su, Yuan-Yuan Wang, Cai-Ping Tan, Liang-Nian Ji & Zong-Wan Mao
Pages: 3147-3162
Published online: 27 Feb 2023
AbstractforReversal of multidrug resistance in MCF-7/Adr cells by codelivery of doxorubicin and BCL2 siRNA using a folic acid-conjugated polyethylenimine hydroxypropyl-β-cyclodextrin nanocarrier | Full Text | References | PDF (5 MB)
  • 86 Views
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Article
Delivery as nanoparticles reduces imatinib mesylate-induced cardiotoxicity and improves anticancer activity
Gregory Marslin, Ann Mary Revina, Vinoth Kumar Megraj Khandelwal, Krishnamoorthy Balakumar, Jose Prakash, Gregory Franklin & Caroline J Sheeba
Pages: 3163-3170
Published online: 24 Apr 2015
AbstractforDelivery as nanoparticles reduces imatinib mesylate-induced cardiotoxicity and improves anticancer activity | Full Text | References | PDF (1.8 MB)
  • 184 Views
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Article
Formation of curcumin nanoparticles via solution-enhanced dispersion by supercritical CO2
Zheng Zhao, Maobin Xie, Yi Li, Aizheng Chen, Gang Li, Jing Zhang, Huawen Hu, Xinyu Wang & Shipu Li
Pages: 3171-3181
Published online: 29 Apr 2015
AbstractforFormation of curcumin nanoparticles via solution-enhanced dispersion by supercritical CO2 | Full Text | References | PDF (4.5 MB)
  • 207 Views
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Review

Review Article
Epigenetic mechanisms in cancer: push and pull between kneaded erasers and fate writers
Ammad Ahmad Farooqi, Jen-Yang Tang, Ruei-Nian Li, Muhammad Ismail, Yung-Ting Chang, Chih-Wen Shu, Shyng-Shiou F Yuan, Jing-Ru Liu, Qaisar Mansoor, Chih-Jen Huang & Hsueh-Wei Chang
Pages: 3183-3191
Published online: 24 Apr 2015
AbstractforEpigenetic mechanisms in cancer: push and pull between kneaded erasers and fate writers | Full Text | References | PDF (224 KB)
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Original Research

Article
Integration of nondegradable polystyrene and degradable gelatin in a core–sheath nanofibrous patch for pelvic reconstruction
Liangpeng Ge, Qingtao Li, Junzi Jiang, Xiaoyan You, Zuohua Liu, Wen Zhong, Yong Huang & Malcolm MQ Xing
Pages: 3193-3201
Published online: 24 Apr 2015
AbstractforIntegration of nondegradable polystyrene and degradable gelatin in a core–sheath nanofibrous patch for pelvic reconstruction | Full Text | References | PDF (4.9 MB)
  • 53 Views
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Article
Greener synthesis of electrospun collagen/hydroxyapatite composite fibers with an excellent microstructure for bone tissue engineering
Yuanyuan Zhou, Hongchang Yao, Jianshe Wang, Dalu Wang, Qian Liu & Zhongjun Li
Pages: 3203-3215
Published online: 29 Apr 2015
AbstractforGreener synthesis of electrospun collagen/hydroxyapatite composite fibers with an excellent microstructure for bone tissue engineering | Full Text | References | PDF (7.2 MB)
  • 163 Views
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Article
Oxidative stress by layered double hydroxide nanoparticles via an SFK-JNK and p38-NF-κB signaling pathway mediates induction of interleukin-6 and interleukin-8 in human lung epithelial cells
Soo-Jin Choi, Hee-Jeong Paek & Jin Yu
Pages: 3217-3229
Published online: 27 Feb 2023
AbstractforOxidative stress by layered double hydroxide nanoparticles via an SFK-JNK and p38-NF-κB signaling pathway mediates induction of interleukin-6 and interleukin-8 in human lung epithelial cells | Full Text | References | PDF (2.6 MB)
  • 65 Views
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Article
Gold nanoparticle-based beacon to detect STAT5b mRNA expression in living cells: a case optimized by bioinformatics screen
Dawei Deng, Yang Li, Jianpeng Xue, Jie Wang, Guanhua Ai, Xin Li & Yueqing Gu
Pages: 3231-3244
Published online: 28 Apr 2015
AbstractforGold nanoparticle-based beacon to detect STAT5b mRNA expression in living cells: a case optimized by bioinformatics screen | Full Text | References | PDF (3.7 MB)
  • 61 Views
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Review

Review Article
Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness
Igor Khalin, Renad Alyautdin, Ganna Kocherga & Muhamad Abu Bakar
Pages: 3245-3267
Published online: 30 Apr 2015
AbstractforTargeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness | Full Text | References | PDF (1.2 MB)
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Original Research

Article
The ability of streptomycin-loaded chitosan-coated magnetic nanocomposites to possess antimicrobial and antituberculosis activities
Mohamed Ezzat El Zowalaty, Samer Hassan Hussein Al Ali, Mohamed I Husseiny, Benjamin M Geilich, Thomas J Webster & Mohd Zobir Hussein
Pages: 3269-3274
Published online: 30 Apr 2015
AbstractforThe ability of streptomycin-loaded chitosan-coated magnetic nanocomposites to possess antimicrobial and antituberculosis activities | Full Text | References | PDF (450.7 KB)
  • 133 Views
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Article
Inducing cell cycle arrest and apoptosis by dimercaptosuccinic acid modified Fe3O4 magnetic nanoparticles combined with nontoxic concentration of bortezomib and gambogic acid in RPMI-8226 cells
Wei Zhang, Lixing Qiao, Xinchao Wang, Ravichandran Senthilkumar, Fei Wang & Baoan Chen
Pages: 3275-3289
Published online: 30 Apr 2015
AbstractforInducing cell cycle arrest and apoptosis by dimercaptosuccinic acid modified Fe3O4 magnetic nanoparticles combined with nontoxic concentration of bortezomib and gambogic acid in RPMI-8226 cells | Full Text | References | PDF (7.1 MB)
  • 70 Views
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Article
Hydroxypropyl-β-cyclodextrin functionalized calcium carbonate microparticles as a potential carrier for enhancing oral delivery of water-insoluble drugs
Lihua Zhang, Wufu Zhu, Qisi Lin, Jin Han, Liqun Jiang & Yanzhuo Zhang
Pages: 3291-3302
Published online: 30 Apr 2015
AbstractforHydroxypropyl-β-cyclodextrin functionalized calcium carbonate microparticles as a potential carrier for enhancing oral delivery of water-insoluble drugs | Full Text | References | PDF (3.2 MB)
  • 79 Views
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Article
Effective small interfering RNA delivery in vitro via a new stearylated cationic peptide
Baoling Chen, Ran Pan, Diana Askhatova & P Chen
Pages: 3303-3314
Published online: 02 May 2015
AbstractforEffective small interfering RNA delivery in vitro via a new stearylated cationic peptide | Full Text | References | PDF (2.7 MB)
  • 52 Views
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Rapid Communication

Article
Functionalized magnetic iron oxide/alginate core-shell nanoparticles for targeting hyperthermia
Shih-Hsiang Liao, Chia-Hung Liu, Bishnu Prasad Bastakoti, Norihiro Suzuki, Yung Chang, Yusuke Yamauchi, Feng-Huei Lin & Kevin C-W Wu
Pages: 3315-3328
Published online: 04 May 2015
AbstractforFunctionalized magnetic iron oxide/alginate core-shell nanoparticles for targeting hyperthermia | Full Text | References | PDF (2.9 MB)
  • 217 Views
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Original Research

Article
Sustained release of bactericidal concentrations of penicillin in the pleural space via an antibiotic-eluting pigtail catheter coated with electrospun nanofibers: results from in vivo and in vitro studies
Yin-Kai Chao, Cheng-Hung Lee, Kuo-Sheng Liu, Yi-Chuan Wang, Chih-Wei Wang & Shih-Jung Liu
Pages: 3329-3336
Published online: 04 May 2015
AbstractforSustained release of bactericidal concentrations of penicillin in the pleural space via an antibiotic-eluting pigtail catheter coated with electrospun nanofibers: results from in vivo and in vitro studies | Full Text | References | PDF (2.9 MB)
  • 81 Views
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Article
Electrospun nanofibrous SF/P(LLA-CL) membrane: a potential substratum for endothelial keratoplasty
Junzhao Chen, Chenxi Yan, Mengyu Zhu, Qinke Yao, Chunyi Shao, Wenjuan Lu, Jing Wang, Xiumei Mo, Ping Gu, Yao Fu & Xianqun Fan
Pages: 3337-3350
Published online: 05 May 2015
AbstractforElectrospun nanofibrous SF/P(LLA-CL) membrane: a potential substratum for endothelial keratoplasty | Full Text | References | PDF (6.9 MB)
  • 122 Views
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Article
Selective inhibition of MG-63 osteosarcoma cell proliferation induced by curcumin-loaded self-assembled arginine-rich-RGD nanospheres
Run Chang, Linlin Sun & Thomas J Webster
Pages: 3351-3365
Published online: 05 May 2015
AbstractforSelective inhibition of MG-63 osteosarcoma cell proliferation induced by curcumin-loaded self-assembled arginine-rich-RGD nanospheres | Full Text | References | PDF (4.3 MB)
  • 72 Views
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Article
Photoactive TiO2 antibacterial coating on surgical external fixation pins for clinical application
Guillaume Villatte, Christophe Massard, Stéphane Descamps, Yves Sibaud, Christiane Forestier & Komla-Oscar Awitor
Pages: 3367-3375
Published online: 06 May 2015
AbstractforPhotoactive TiO2 antibacterial coating on surgical external fixation pins for clinical application | Full Text | References | PDF (2.2 MB)
  • 104 Views
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Article
Biochemical characterization of the interactions between doxorubicin and lipidic GM1 micelles with or without paclitaxel loading
Victoria Leonhard, Roxana V Alasino, Ismael D Bianco, Ariel G Garro, Valeria Heredia & Dante M Beltramo
Pages: 3377-3388
Published online: 27 Feb 2023
AbstractforBiochemical characterization of the interactions between doxorubicin and lipidic GM1 micelles with or without paclitaxel loading | Full Text | References | PDF (2.5 MB)
  • 48 Views
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Article
Anticancer activity of biostabilized selenium nanorods synthesized by Streptomyces bikiniensis strain Ess_amA-1
Maged Sayed Ahmad, Manal Mohamed Yasser, Essam Nageh Sholkamy, Ali Mohamed Ali & Magda Mohamed Mehanni
Pages: 3389-3401
Published online: 06 May 2015
AbstractforAnticancer activity of biostabilized selenium nanorods synthesized by Streptomyces bikiniensis strain Ess_amA-1 | Full Text | References | PDF (2.7 MB)
  • 144 Views
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Article
Reduction-responsive cross-linked stearyl peptide for effective delivery of plasmid DNA
Chong Yao, Zongguang Tai, Xiaoyu Wang, Jiyong Liu, Quangang Zhu, Xin Wu, Lijuan Zhang, Wei Zhang, Jing Tian, Yuan Gao & Shen Gao
Pages: 3403-3416
Published online: 08 May 2015
AbstractforReduction-responsive cross-linked stearyl peptide for effective delivery of plasmid DNA | Full Text | References | PDF (8.1 MB)
  • 46 Views
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Methodology

Article
Novel stable cytokine delivery system in physiological pH solution: chitosan oligosaccharide/heparin nanoparticles
Bin Wang, Ling Tan, Dengpu Deng, Ting Lu, Changwei Zhou, Zhongkui Li, Zhenjie Tang, Zhongshi Wu & Hao Tang
Pages: 3417-3427
Published online: 08 May 2015
AbstractforNovel stable cytokine delivery system in physiological pH solution: chitosan oligosaccharide/heparin nanoparticles | Full Text | References | PDF (3.7 MB)
  • 76 Views
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Original Research

Article
Effects of PVA coated nanoparticles on human immune cells
Cindy Strehl, Timo Gaber, Lionel Maurizi, Martin Hahne, Roman Rauch, Paula Hoff, Thomas Häupl, Margarethe Hofmann-Amtenbrink, A Robin Poole, Heinrich Hofmann & Frank Buttgereit
Pages: 3429-3445
Published online: 08 May 2015
AbstractforEffects of PVA coated nanoparticles on human immune cells | Full Text | References | PDF (3 MB)
  • 133 Views
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Article
Amino-functionalized poly(l-lactide) lamellar single crystals as a valuable substrate for delivery of HPV16-E7 tumor antigen in vaccine development
Paola Di Bonito, Linda Petrone, Gabriele Casini, Iolanda Francolini, Maria Grazia Ammendolia, Luisa Accardi, Antonella Piozzi, Lucio D’Ilario & Andrea Martinelli
Pages: 3447-3458
Published online: 08 May 2015
AbstractforAmino-functionalized poly(l-lactide) lamellar single crystals as a valuable substrate for delivery of HPV16-E7 tumor antigen in vaccine development | Full Text | References | PDF (2.4 MB)
  • 85 Views
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Article
Nanogel-crosslinked nanoparticles increase the inhibitory effects of W9 synthetic peptide on bone loss in a murine bone resorption model
Toshimi Sato, Neil Alles, Masud Khan, Kenichi Nagano, Mariko Takahashi, Yukihiko Tamura, Asako Shimoda, Keiichi Ohya, Kazunari Akiyoshi & Kazuhiro Aoki
Pages: 3459-3473
Published online: 11 May 2015
AbstractforNanogel-crosslinked nanoparticles increase the inhibitory effects of W9 synthetic peptide on bone loss in a murine bone resorption model | Full Text | References | PDF (5.6 MB)
  • 55 Views
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Article
Delivery of microRNA-146a with polyethylenimine nanoparticles inhibits renal fibrosis in vivo
Yoshiyuki Morishita, Toshimi Imai, Hiromichi Yoshizawa, Minami Watanabe, Kenichi Ishibashi, Shigeaki Muto & Daisuke Nagata
Pages: 3475-3488
Published online: 11 May 2015
AbstractforDelivery of microRNA-146a with polyethylenimine nanoparticles inhibits renal fibrosis in vivo | Full Text | References | PDF (5.9 MB)
  • 106 Views
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Article
pH-sensitive poly(lactide-co-glycolide) nanoparticle composite microcapsules for oral delivery of insulin
Shaoping Sun, Na Liang, Hiromitsu Yamamoto, Yoshiaki Kawashima, Fude Cui & Pengfei Yan
Pages: 3489-3498
Published online: 11 May 2015
AbstractforpH-sensitive poly(lactide-co-glycolide) nanoparticle composite microcapsules for oral delivery of insulin | Full Text | References | PDF (3 MB)
  • 72 Views
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Article
Nanofabrication of methylglyoxal with chitosan biopolymer: a potential tool for enhancement of its anticancer effect
Aparajita Pal, Dipa Talukdar, Anirban Roy, Subhankar Ray, Asish Mallick, Chitra Mandal & Manju Ray
Pages: 3499-3518
Published online: 12 May 2015
AbstractforNanofabrication of methylglyoxal with chitosan biopolymer: a potential tool for enhancement of its anticancer effect | Full Text | References | PDF (8.4 MB)
  • 60 Views
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Article
Functionalized self-assembling peptide improves INS-1 β-cell function and proliferation via the integrin/FAK/ERK/cyclin pathway
Jingping Liu, Shuyun Liu, Younan Chen, Xiaojun Zhao, Yanrong Lu & Jingqiu Cheng
Pages: 3519-3531
Published online: 13 May 2015
AbstractforFunctionalized self-assembling peptide improves INS-1 β-cell function and proliferation via the integrin/FAK/ERK/cyclin pathway | Full Text | References | PDF (2.8 MB)
  • 65 Views
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Article
Accelerated blood clearance phenomenon upon cross-administration of PEGylated nanocarriers in beagle dogs
Chunling Wang, Xiaobo Cheng, Yuqing Su, Ying Pei, Yanzhi Song, Jiao Jiao, Zhenjun Huang, Yanfei Ma, Yinming Dong, Ying Yao, Jingjing Fan, Han Ta, Xinrong Liu, Hui Xu & Yihui Deng
Pages: 3533-3545
Published online: 14 May 2015
AbstractforAccelerated blood clearance phenomenon upon cross-administration of PEGylated nanocarriers in beagle dogs | Full Text | References | PDF (2.2 MB)
  • 89 Views
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Review

Review Article
Application of dental nanomaterials: potential toxicity to the central nervous system
Xiaoli Feng, Aijie Chen, Yanli Zhang, Jianfeng Wang, Longquan Shao & Limin Wei
Pages: 3547-3565
Published online: 14 May 2015
AbstractforApplication of dental nanomaterials: potential toxicity to the central nervous system | Full Text | References | PDF (1.6 MB)
  • 213 Views
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Original Research

Article
A single dose of dexamethasone encapsulated in polyethylene glycol-coated polylactic acid nanoparticles attenuates cisplatin-induced hearing loss following round window membrane administration
Changling Sun, Xueling Wang, Zhaozhu Zheng, Dongye Chen, Xiaoqin Wang, Fuxin Shi, Dehong Yu & Hao Wu
Pages: 3567-3579
Published online: 14 May 2015
AbstractforA single dose of dexamethasone encapsulated in polyethylene glycol-coated polylactic acid nanoparticles attenuates cisplatin-induced hearing loss following round window membrane administration | Full Text | References | PDF (2.3 MB)
  • 110 Views
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Article
Amalgamation of complex iron(III) ions and iron nanoclusters with MWCNTs as a route to potential T2 MRI contrast agents
Nikodem Kuźnik, Mateusz M Tomczyk, Marzena Wyskocka, Łukasz Przypis, Artur P Herman, Rafał Jędrysiak, Krzysztof K Koziol & Sławomir Boncel
Pages: 3581-3591
Published online: 14 May 2015
AbstractforAmalgamation of complex iron(III) ions and iron nanoclusters with MWCNTs as a route to potential T2 MRI contrast agents | Full Text | References | PDF (575.3 KB)
  • 48 Views
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Article
Enhanced pharmacological activity of Vitamin B12 and Penicillin as nanoparticles
Inbar Yariv, Anat Lipovsky, Aharon Gedanken, Rachel Lubart & Dror Fixler
Pages: 3593-3601
Published online: 15 May 2015
AbstractforEnhanced pharmacological activity of Vitamin B12 and Penicillin as nanoparticles | Full Text | References | PDF (3.8 MB)
  • 109 Views
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Article
Development and molecular characterization of polymeric micro-nanofibrous scaffold of a defined 3-D niche for in vitro chemosensitivity analysis against acute myeloid leukemia cells
Maya S Nair, Ullas Mony, Deepthy Menon, Manzoor Koyakutty, Neeraj Sidharthan, Keechilat Pavithran, Shantikumar V Nair & Krishnakumar N Menon
Pages: 3603-3622
Published online: 15 May 2015
AbstractforDevelopment and molecular characterization of polymeric micro-nanofibrous scaffold of a defined 3-D niche for in vitro chemosensitivity analysis against acute myeloid leukemia cells | Full Text | References | PDF (6 MB)
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Article
Doxorubicin-loaded aromatic imine-contained amphiphilic branched star polymer micelles: synthesis, self-assembly, and drug delivery
Liang Qiu, Chun-Yan Hong & Cai-Yuan Pan
Pages: 3623-3640
Published online: 18 May 2015
AbstractforDoxorubicin-loaded aromatic imine-contained amphiphilic branched star polymer micelles: synthesis, self-assembly, and drug delivery | Full Text | References | PDF (4.9 MB)
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Article
External beam radiotherapy synergizes 188Re-liposome against human esophageal cancer xenograft and modulates 188Re-liposome pharmacokinetics
Chih-Hsien Chang, Shin-Yi Liu, Chih-Wen Chi, Hsiang-Lin Yu, Tsui-Jung Chang, Tung-Hu Tsai, Te-Wei Lee & Yu-Jen Chen
Pages: 3641-3649
Published online: 19 May 2015
AbstractforExternal beam radiotherapy synergizes 188Re-liposome against human esophageal cancer xenograft and modulates 188Re-liposome pharmacokinetics | Full Text | References | PDF (2 MB)
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Article
Dual-color immunofluorescent labeling with quantum dots of the diabetes-associated proteins aldose reductase and Toll-like receptor 4 in the kidneys of diabetic rats
Xiaomin Liu, Rui Hu, Hongwei Lian, Yang Liu, Jing Liu, Jianwei Liu, Guimiao Lin, Liwei Liu, Xiaojian Duan, Ken-Tye Yong & Ling Ye
Pages: 3651-3662
Published online: 20 May 2015
AbstractforDual-color immunofluorescent labeling with quantum dots of the diabetes-associated proteins aldose reductase and Toll-like receptor 4 in the kidneys of diabetic rats | Full Text | References | PDF (4.7 MB)
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Article
Cetuximab-conjugated iron oxide nanoparticles for cancer imaging and therapy
Shih-Heng Tseng, Min-Yuan Chou & I-Ming Chu
Pages: 3663-3685
Published online: 20 May 2015
AbstractforCetuximab-conjugated iron oxide nanoparticles for cancer imaging and therapy | Full Text | References | PDF (5.4 MB)
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Article
Effects of carbon nanofiber on physiology of Drosophila
Shin-Hae Lee, Hye-Yeon Lee, Eun-Ji Lee, Dongwoo Khang & Kyung-Jin Min
Pages: 3687-3697
Published online: 21 May 2015
AbstractforEffects of carbon nanofiber on physiology of Drosophila | Full Text | References | PDF (1.7 MB)
  • 109 Views
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Article
Efficacy and mechanism of tanshinone IIA liquid nanoparticles in preventing experimental postoperative peritoneal adhesions in vivo and in vitro
Fei Qin, Yun Ma, Xiao Li, Xian Wang, Yuanyi Wei, Chuqi Hou, Si Lin, Lianbing Hou & Chengxi Wang
Pages: 3699-3717
Published online: 21 May 2015
AbstractforEfficacy and mechanism of tanshinone IIA liquid nanoparticles in preventing experimental postoperative peritoneal adhesions in vivo and in vitro | Full Text | References | PDF (12.8 MB)
  • 68 Views
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Article
Upconversion nanoparticle-mediated photodynamic therapy induces THP-1 macrophage apoptosis via ROS bursts and activation of the mitochondrial caspase pathway
Xing Zhu, Hao Wang, Longbin Zheng, Zhaoyu Zhong, Xuesong Li, Jing Zhao, Jiayuan Kou, Yueqing Jiang, Xiufeng Zheng, Zhongni Liu, Hongxia Li, Wenwu Cao, Ye Tian, You Wang & Liming Yang
Pages: 3719-3736
Published online: 22 May 2015
AbstractforUpconversion nanoparticle-mediated photodynamic therapy induces THP-1 macrophage apoptosis via ROS bursts and activation of the mitochondrial caspase pathway | Full Text | References | PDF (4.8 MB)
  • 98 Views
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Article
Delivery of baicalein and paclitaxel using self-assembled nanoparticles: synergistic antitumor effect in vitro and in vivo
Wei Wang, Mei Xi, Xuezhong Duan, Yong Wang & Fansheng Kong
Pages: 3737-3750
Published online: 22 May 2015
AbstractforDelivery of baicalein and paclitaxel using self-assembled nanoparticles: synergistic antitumor effect in vitro and in vivo | Full Text | References | PDF (1.5 MB)
  • 135 Views
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Article
Nanoalumina induces apoptosis by impairing antioxidant enzyme systems in human hepatocarcinoma cells
Saud Alarifi, Daoud Ali & Saad Alkahtani
Pages: 3751-3760
Published online: 25 May 2015
AbstractforNanoalumina induces apoptosis by impairing antioxidant enzyme systems in human hepatocarcinoma cells | Full Text | References | PDF (2.3 MB)
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Review

Review Article
Value of phagocyte function screening for immunotoxicity of nanoparticles in vivo
Eleonore Fröhlich
Pages: 3761-3778
Published online: 26 May 2015
AbstractforValue of phagocyte function screening for immunotoxicity of nanoparticles in vivo | Full Text | References | PDF (611.1 KB)
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Original Research

Article
Magnetic resonance imaging of folic acid-coated magnetite nanoparticles reflects tissue biodistribution of long-acting antiretroviral therapy
Tianyuzi Li, Howard E Gendelman, Gang Zhang, Pavan Puligujja, JoEllyn M McMillan, Tatiana K Bronich, Benson Edagwa, Xin-Ming Liu & Michael D Boska
Pages: 3779-3790
Published online: 03 Jun 2015
AbstractforMagnetic resonance imaging of folic acid-coated magnetite nanoparticles reflects tissue biodistribution of long-acting antiretroviral therapy | Full Text | References | PDF (2.9 MB)
  • 57 Views
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Article
GX1-conjugated poly(lactic acid) nanoparticles encapsulating Endostar for improved in vivo anticolorectal cancer treatment
Yang Du, Qian Zhang, Lijia Jing, Xiaolong Liang, Chongwei Chi, Yaqian Li, Xin Yang, Zhifei Dai & Jie Tian
Pages: 3791-3802
Published online: 28 May 2015
AbstractforGX1-conjugated poly(lactic acid) nanoparticles encapsulating Endostar for improved in vivo anticolorectal cancer treatment | Full Text | References | PDF (3.8 MB)
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Article
Gold nanoparticles allow detection of early-stage edema in mice via computed tomography imaging
Jenny Domey, Ulf Teichgräber & Ingrid Hilger
Pages: 3803-3814
Published online: 02 Jun 2015
AbstractforGold nanoparticles allow detection of early-stage edema in mice via computed tomography imaging | Full Text | References | PDF (2.1 MB)
  • 78 Views
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Article
Mesoporous bioactive glass surface modified poly(lactic-co-glycolic acid) electrospun fibrous scaffold for bone regeneration
Shijie Chen, Zhiyuan Jian, Linsheng Huang, Wei Xu, Shaohua Liu, Dajiang Song, Zongmiao Wan, Amanda Vaughn, Ruisen Zhan, Chaoyue Zhang, Song Wu, Minghua Hu & Jinsong Li
Pages: 3815-3827
Published online: 02 Jun 2015
AbstractforMesoporous bioactive glass surface modified poly(lactic-co-glycolic acid) electrospun fibrous scaffold for bone regeneration | Full Text | References | PDF (6.9 MB)
  • 101 Views
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Article
Transactivator of transcription (TAT) peptide– chitosan functionalized multiwalled carbon nanotubes as a potential drug delivery vehicle for cancer therapy
Xia Dong, Lanxia Liu, Dunwan Zhu, Hailing Zhang & Xigang Leng
Pages: 3829-3841
Published online: 03 Jun 2015
AbstractforTransactivator of transcription (TAT) peptide– chitosan functionalized multiwalled carbon nanotubes as a potential drug delivery vehicle for cancer therapy | Full Text | References | PDF (3.5 MB)
  • 82 Views
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Article
Magnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells
Katarzyna Niemirowicz, Izabela Prokop, Agnieszka Z Wilczewska, Urszula Wnorowska, Ewelina Piktel, Marzena Wątek, Paul B Savage & Robert Bucki
Pages: 3843-3853
Published online: 04 Jun 2015
AbstractforMagnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells | Full Text | References | PDF (3.1 MB)
  • 168 Views
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Article
Effects of graphene plates’ adoption on the microstructure, mechanical properties, and in vivo biocompatibility of calcium silicate coating
Youtao Xie, Hongqin Li, Chuanxian Ding, Xuebin Zheng & Kai Li
Pages: 3855-3863
Published online: 08 Jun 2015
AbstractforEffects of graphene plates’ adoption on the microstructure, mechanical properties, and in vivo biocompatibility of calcium silicate coating | Full Text | References | PDF (7.4 MB)
  • 57 Views
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Article
Development and optimization of a self-microemulsifying drug delivery system for ator vastatin calcium by using d-optimal mixture design
Dong Woo Yeom, Ye Seul Song, Sung Rae Kim, Sang Gon Lee, Min Hyung Kang, Sangkil Lee & Young Wook Choi
Pages: 3865-3878
Published online: 05 Jun 2015
AbstractforDevelopment and optimization of a self-microemulsifying drug delivery system for ator vastatin calcium by using d-optimal mixture design | Full Text | References | PDF (1.5 MB)
  • 248 Views
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Article
Formulation optimization of galantamine hydrobromide loaded gel drug reservoirs in transdermal patch for Alzheimer’s disease
Fong Yen Woo, Mahiran Basri, Hamid Reza Fard Masoumi, Mansor B Ahmad & Maznah Ismail
Pages: 3879-3886
Published online: 27 Feb 2023
AbstractforFormulation optimization of galantamine hydrobromide loaded gel drug reservoirs in transdermal patch for Alzheimer’s disease | Full Text | References | PDF (472.8 KB)
  • 135 Views
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Article
Tuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants
Hui Wang, Yue-Kun Lai, Ru-Yue Zheng, Ye Bian, Ke-Qin Zhang & Chang-Jian Lin
Pages: 3887-3896
Published online: 08 Jun 2015
AbstractforTuning the surface microstructure of titanate coatings on titanium implants for enhancing bioactivity of implants | Full Text | References | PDF (6.3 MB)
  • 66 Views
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Article
Chitosan–tripolyphosphate nanoparticles as Arrabidaea chica standardized extract carrier: synthesis, characterization, biocompatibility, and antiulcerogenic activity
Leila Servat-Medina, Alvaro González-Gómez, Felisa Reyes-Ortega, Ilza Maria Oliveira Sousa, Nubia de Cássia Almeida Queiroz, Patricia Maria Wiziack Zago, Michelle Pedrosa Jorge, Karin Maia Monteiro, João Ernesto de Carvalho, Julio San Román & Mary Ann Foglio
Pages: 3897-3909
Published online: 09 Jun 2015
AbstractforChitosan–tripolyphosphate nanoparticles as Arrabidaea chica standardized extract carrier: synthesis, characterization, biocompatibility, and antiulcerogenic activity | Full Text | References | PDF (2.1 MB)
  • 262 Views
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Article
Engineering of lipid prodrug-based, hyaluronic acid-decorated nanostructured lipid carriers platform for 5-fluorouracil and cisplatin combination gastric cancer therapy
Chun-Ying Qu, Min Zhou, Ying-wei Chen, Mei-mei Chen, Feng Shen & Lei-Ming Xu
Pages: 3911-3920
Published online: 10 Jun 2015
AbstractforEngineering of lipid prodrug-based, hyaluronic acid-decorated nanostructured lipid carriers platform for 5-fluorouracil and cisplatin combination gastric cancer therapy | Full Text | References | PDF (680.2 KB)
  • 201 Views
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Article
Poly(n-butylcyanoacrylate) nanoparticles for oral delivery of quercetin: preparation, characterization, and pharmacokinetics and biodistribution studies in Wistar rats
Mayur Bagad & Zaved Ahmed Khan
Pages: 3921-3935
Published online: 10 Jun 2015
AbstractforPoly(n-butylcyanoacrylate) nanoparticles for oral delivery of quercetin: preparation, characterization, and pharmacokinetics and biodistribution studies in Wistar rats | Full Text | References | PDF (3.9 MB)
  • 161 Views
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Article
Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells
Jessica Swanner, Jade Mims, David L Carroll, Steven A Akman, Cristina M Furdui, Suzy V Torti & Ravi N Singh
Pages: 3937-3953
Published online: 11 Jun 2015
AbstractforDifferential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells | Full Text | References | PDF (2.9 MB)
  • 192 Views
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Review

Review Article
Multifaceted applications of bile salts in pharmacy: an emphasis on nanomedicine
Yosra SR Elnaggar
Pages: 3955-3971
Published online: 12 Jun 2015
AbstractforMultifaceted applications of bile salts in pharmacy: an emphasis on nanomedicine | Full Text | References | PDF (2.1 MB)
  • 184 Views
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Original Research

Article
Utilization of nanotechnology to enhance percutaneous absorption of acyclovir in the treatment of herpes simplex viral infections
Mutlaq M Al-Subaie, Khaled M Hosny, Khalid Mohamed El-Say, Tarek A Ahmed & Bader M Aljaeid
Pages: 3973-3985
Published online: 15 Jun 2015
AbstractforUtilization of nanotechnology to enhance percutaneous absorption of acyclovir in the treatment of herpes simplex viral infections | Full Text | References | PDF (2.4 MB)
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Corrigendum

Correction
Cellular entry of nanoparticles via serum sensitive clathrin-mediated endocytosis, and plasma membrane permeabilization [Corrigendum]
Page: 3987
Published online: 16 Jun 2015
CitationforCellular entry of nanoparticles via serum sensitive clathrin-mediated endocytosis, and plasma membrane permeabilization [Corrigendum] | Full Text | PDF (99.2 KB)
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Review

Review Article
Multiple cues on the physiochemical, mesenchymal, and intracellular trafficking interactions with nanocarriers to maximize tumor target efficiency
Sang-Woo Kim & Dongwoo Khang
Pages: 3989-4008
Published online: 27 Feb 2023
AbstractforMultiple cues on the physiochemical, mesenchymal, and intracellular trafficking interactions with nanocarriers to maximize tumor target efficiency | Full Text | References | PDF (6 MB)
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Original Research

Article
Influence of nanotopography on periodontal ligament stem cell functions and cell sheet based periodontal regeneration
Hui Gao, Bei Li, Lingzhou Zhao & Yan Jin
Pages: 4009-4027
Published online: 19 Jun 2015
AbstractforInfluence of nanotopography on periodontal ligament stem cell functions and cell sheet based periodontal regeneration | Full Text | References | PDF (8.6 MB)
  • 87 Views
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Article
Application of nanoparticles for oral delivery of acid-labile lansoprazole in the treatment of gastric ulcer: in vitro and in vivo evaluations
Milind Alai & Wen Jen Lin
Pages: 4029-4041
Published online: 18 Jun 2015
AbstractforApplication of nanoparticles for oral delivery of acid-labile lansoprazole in the treatment of gastric ulcer: in vitro and in vivo evaluations | Full Text | References | PDF (5.3 MB)
  • 261 Views
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Article
RETRACTED ARTICLE: The therapeutic effect of methotrexate-conjugated Pluronic-based polymeric micelles on the folate receptor-rich tumors treatment
Yanzuo Chen, Wei Zhang, YuKun Huang, Feng Gao, Xianyi Sha, Kaiyan Lou & Xiaoling Fang
Pages: 4043-4057
Published online: 19 Jun 2015
AbstractforRETRACTED ARTICLE: The therapeutic effect of methotrexate-conjugated Pluronic-based polymeric micelles on the folate receptor-rich tumors treatment | PDF (6.6 MB)
  • 11 Views
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Article
Optimized zein nanospheres for improved oral bioavailability of atorvastatin
Fahima M Hashem, Majid M Al-Sawahli, Mohamed Nasr & Osama AA Ahmed
Pages: 4059-4069
Published online: 19 Jun 2015
AbstractforOptimized zein nanospheres for improved oral bioavailability of atorvastatin | Full Text | References | PDF (2.1 MB)
  • 87 Views
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Article
Sustained release of VH and rhBMP-2 from nanoporous magnesium–zinc–silicon xerogels for osteomyelitis treatment and bone repair
Fengqian Li, Wen Wu, Li Xiang, Gan Weng, Hua Hong, Hong Jiang & Jun Qian
Pages: 4071-4080
Published online: 22 Jun 2015
AbstractforSustained release of VH and rhBMP-2 from nanoporous magnesium–zinc–silicon xerogels for osteomyelitis treatment and bone repair | Full Text | References | PDF (1.8 MB)
  • 60 Views
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Article
Oral administration of iron-saturated bovine lactoferrin–loaded ceramic nanocapsules for breast cancer therapy and influence on iron and calcium metabolism
Ganesh Mahidhara, Rupinder K Kanwar, Kislay Roy & Jagat R Kanwar
Pages: 4081-4098
Published online: 22 Jun 2015
AbstractforOral administration of iron-saturated bovine lactoferrin–loaded ceramic nanocapsules for breast cancer therapy and influence on iron and calcium metabolism | Full Text | References | PDF (10.2 MB)
  • 103 Views
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Article
Targeted tumor imaging of anti-CD20-polymeric nanoparticles developed for the diagnosis of B-cell malignancies
Sara Capolla, Chiara Garrovo, Sonia Zorzet, Andrea Lorenzon, Enrico Rampazzo, Ruben Spretz, Gabriele Pozzato, Luis Núñez, Claudio Tripodo, Paolo Macor & Stefania Biffi
Pages: 4099-4109
Published online: 27 Feb 2023
AbstractforTargeted tumor imaging of anti-CD20-polymeric nanoparticles developed for the diagnosis of B-cell malignancies | Full Text | References | PDF (2.4 MB)
  • 88 Views
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Article
Enzyme-responsive nanocomposites for wound infection prophylaxis in burn management: in vitro evaluation of their compatibility with healing processes
Verena Grützner, Ronald E Unger, Grit Baier, Lars Choritz, Christian Freese, Thomas Böse, Katharina Landfester & C James Kirkpatrick
Pages: 4111-4124
Published online: 24 Jun 2015
AbstractforEnzyme-responsive nanocomposites for wound infection prophylaxis in burn management: in vitro evaluation of their compatibility with healing processes | Full Text | References | PDF (10.5 MB)
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Article
Degradability, bioactivity, and osteogenesis of biocomposite scaffolds of lithium-containing mesoporous bioglass and mPEG-PLGA-b-PLL copolymer
Yanrong Cai, Lieping Guo, Hongxing Shen, Xiaofei An, Hong Jiang, Fang Ji & Yunfei Niu
Pages: 4125-4136
Published online: 24 Jun 2015
AbstractforDegradability, bioactivity, and osteogenesis of biocomposite scaffolds of lithium-containing mesoporous bioglass and mPEG-PLGA-b-PLL copolymer | Full Text | References | PDF (4.8 MB)
  • 68 Views
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Article
MRI-detectable polymeric micelles incorporating platinum anticancer drugs enhance survival in an advanced hepatocellular carcinoma model
Nguyen Quoc Vinh, Shigeyuki Naka, Horacio Cabral, Hiroyuki Murayama, Sachiko Kaida, Kazunori Kataoka, Shigehiro Morikawa & Tohru Tani
Pages: 4137-4147
Published online: 25 Jun 2015
AbstractforMRI-detectable polymeric micelles incorporating platinum anticancer drugs enhance survival in an advanced hepatocellular carcinoma model | Full Text | References | PDF (3.2 MB)
  • 68 Views
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Article
Biodegradable double nanocapsule as a novel multifunctional carrier for drug delivery and cell imaging
Kun Qian, Jing Wu, Enqi Zhang, Yingge Zhang & Ailing Fu
Pages: 4149-4157
Published online: 25 Jun 2015
AbstractforBiodegradable double nanocapsule as a novel multifunctional carrier for drug delivery and cell imaging | Full Text | References | PDF (2.4 MB)
  • 71 Views
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Article
Virosomes of hepatitis B virus envelope L proteins containing doxorubicin: synergistic enhancement of human liver-specific antitumor growth activity by radiotherapy
Qiushi Liu, Joohee Jung, Masaharu Somiya, Masumi Iijima, Nobuo Yoshimoto, Tomoaki Niimi, Andrés D Maturana, Seol Hwa Shin, Seong-Yun Jeong, Eun Kyung Choi & Shun’ichi Kuroda
Pages: 4159-4172
Published online: 25 Jun 2015
AbstractforVirosomes of hepatitis B virus envelope L proteins containing doxorubicin: synergistic enhancement of human liver-specific antitumor growth activity by radiotherapy | Full Text | References | PDF (5 MB)
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Article
Effects of zinc oxide nanoparticles on Kupffer cell phagosomal motility, bacterial clearance, and liver function
Christa Y Watson, Ramon M Molina, Andressa Louzada, Kimberly M Murdaugh, Thomas C Donaghey & Joseph D Brain
Pages: 4173-4184
Published online: 26 Jun 2015
AbstractforEffects of zinc oxide nanoparticles on Kupffer cell phagosomal motility, bacterial clearance, and liver function | Full Text | References | PDF (6.3 MB)
  • 98 Views
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Article
Flow cytometry for intracellular SPION quantification: specificity and sensitivity in comparison with spectroscopic methods
Ralf P Friedrich, Christina Janko, Marina Poettler, Philipp Tripal, Jan Zaloga, Iwona Cicha, Stephan Dürr, Johannes Nowak, Stefan Odenbach, Ioana Slabu, Maik Liebl, Lutz Trahms, Marcus Stapf, Ingrid Hilger, Stefan Lyer & Christoph Alexiou
Pages: 4185-4201
Published online: 26 Jun 2015
AbstractforFlow cytometry for intracellular SPION quantification: specificity and sensitivity in comparison with spectroscopic methods | Full Text | References | PDF (4 MB)
  • 174 Views
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Article
Comparative assessment of the apoptotic potential of silver nanoparticles synthesized by Bacillus tequilensis and Calocybe indica in MDA-MB-231 human breast cancer cells: targeting p53 for anticancer therapy
Sangiliyandi Gurunathan, Jung Hyun Park, Jae Woong Han & Jin-Hoi Kim
Pages: 4203-4223
Published online: 27 Feb 2023
AbstractforComparative assessment of the apoptotic potential of silver nanoparticles synthesized by Bacillus tequilensis and Calocybe indica in MDA-MB-231 human breast cancer cells: targeting p53 for anticancer therapy | Full Text | References | PDF (4.2 MB)
  • 439 Views
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Article
Nonspecifically enhanced therapeutic effects of vincristine on multidrug-resistant cancers when coencapsulated with quinine in liposomes
Yuzhen Xu & Liyan Qiu
Pages: 4225-4237
Published online: 27 Feb 2023
AbstractforNonspecifically enhanced therapeutic effects of vincristine on multidrug-resistant cancers when coencapsulated with quinine in liposomes | Full Text | References | PDF (2.7 MB)
  • 62 Views
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Article
Compound antimalarial ethosomal cataplasm: preparation, evaluation, and mechanism of penetration enhancement
Shuo Shen, Shu-Zhi Liu, Yu-Shi Zhang, Mao-Bo Du, Ai-Hua Liang, Li-Hua Song & Zu-Guang Ye
Pages: 4239-4253
Published online: 30 Jun 2015
AbstractforCompound antimalarial ethosomal cataplasm: preparation, evaluation, and mechanism of penetration enhancement | Full Text | References | PDF (4.6 MB)
  • 107 Views
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Article
CaCO3/CaIP6 composite nanoparticles effectively deliver AKT1 small interfering RNA to inhibit human breast cancer growth
Hongyan Zhou, Jinhuan Wei, Qiangsheng Dai, Liping Wang, Junhang Luo, Tuckyun Cheang & Shenming Wang
Pages: 4255-4266
Published online: 27 Feb 2023
AbstractforCaCO3/CaIP6 composite nanoparticles effectively deliver AKT1 small interfering RNA to inhibit human breast cancer growth | Full Text | References | PDF (4.2 MB)
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Review

Review Article
Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
Agnes Aruna John, Aruna Priyadharshni Subramanian, Muthu Vignesh Vellayappan, Arunpandian Balaji, Hemanth Mohandas & Saravana Kumar Jaganathan
Pages: 4267-4277
Published online: 02 Jul 2015
AbstractforCarbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery | Full Text | References | PDF (1.6 MB)
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Original Research

Article
Polyetherimide-grafted Fe3O4@SiO2 nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging
Tingting Li, Xue Shen, Yin Chen, Chengchen Zhang, Jie Yan, Hong Yang, Chunhui Wu, Hongjun Zeng & Yiyao Liu
Pages: 4279-4291
Published online: 27 Feb 2023
AbstractforPolyetherimide-grafted Fe3O4@SiO2 nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging | Full Text | References | PDF (2.9 MB)
  • 113 Views
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Article
Curcumin-loaded colloidal carrier system: formulation optimization, mechanistic insight, ex vivo and in vivo evaluation
Zrien Naz & Farhan Jalees Ahmad
Pages: 4293-4307
Published online: 27 Feb 2023
AbstractforCurcumin-loaded colloidal carrier system: formulation optimization, mechanistic insight, ex vivo and in vivo evaluation | Full Text | References | PDF (3.8 MB)
  • 161 Views
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Article
The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes
Ya-Jing Ye, Yun Wang, Kai-Yan Lou, Yan-Zuo Chen, Rongjun Chen & Feng Gao
Pages: 4309-4319
Published online: 27 Feb 2023
AbstractforThe preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes | Full Text | References | PDF (3.7 MB)
  • 157 Views
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Review

Review Article
Central nervous system toxicity of metallic nanoparticles
Xiaoli Feng, Aijie Chen, Yanli Zhang, Jianfeng Wang, Longquan Shao & Limin Wei
Pages: 4321-4340
Published online: 27 Feb 2023
AbstractforCentral nervous system toxicity of metallic nanoparticles | Full Text | References | PDF (2.2 MB)
  • 287 Views
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Original Research

Article
Preparation and physical characterization of calcium sulfate cement/silica-based mesoporous material composites for controlled release of BMP-2
Honglue Tan, Shengbing Yang, Pengyi Dai, Wuyin Li & Bing Yue
Pages: 4341-4350
Published online: 27 Feb 2023
AbstractforPreparation and physical characterization of calcium sulfate cement/silica-based mesoporous material composites for controlled release of BMP-2 | Full Text | References | PDF (4.5 MB)
  • 56 Views
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Article
Activity of daptomycin- and vancomycin-loaded poly-epsilon-caprolactone microparticles against mature staphylococcal biofilms
Inês Santos Ferreira, Ana F Bettencourt, Lídia MD Gonçalves, Stefanie Kasper, Bertrand Bétrisey, Judith Kikhney, Annette Moter, Andrej Trampuz & António J Almeida
Pages: 4351-4366
Published online: 27 Feb 2023
AbstractforActivity of daptomycin- and vancomycin-loaded poly-epsilon-caprolactone microparticles against mature staphylococcal biofilms | Full Text | References | PDF (2.1 MB)
  • 95 Views
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Article
Inhibition of myeloid differentiation factor 88 signaling mediated by histidine-grafted poly(β-amino ester) ester nanovector induces donor-specific liver allograft tolerance
Fanguo Hu, Hanjie Wang, Shuangnan Zhang, Yao Peng, Lin Su, Jin Chang & Gang Liu
Pages: 4367-4382
Published online: 27 Feb 2023
AbstractforInhibition of myeloid differentiation factor 88 signaling mediated by histidine-grafted poly(β-amino ester) ester nanovector induces donor-specific liver allograft tolerance | Full Text | References | PDF (6.6 MB)
  • 56 Views
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Article
Gold nanoparticles promote osteogenic differentiation in human adipose-derived mesenchymal stem cells through the Wnt/β-catenin signaling pathway
Seon Young Choi, Min Seok Song, Pan Dong Ryu, Anh Thu Ngoc Lam, Sang-Woo Joo & So Yeong Lee
Pages: 4383-4392
Published online: 27 Feb 2023
AbstractforGold nanoparticles promote osteogenic differentiation in human adipose-derived mesenchymal stem cells through the Wnt/β-catenin signaling pathway | Full Text | References | PDF (3 MB)
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Article
Blood group antigen studies using CdTe quantum dots and flow cytometry
Paulo E Cabral Filho, Maria IA Pereira, Heloise P Fernandes, Andre A de Thomaz, Carlos L Cesar, Beate S Santos, Maria L Barjas-Castro & Adriana Fontes
Pages: 4393-4404
Published online: 27 Feb 2023
AbstractforBlood group antigen studies using CdTe quantum dots and flow cytometry | Full Text | References | PDF (1.3 MB)
  • 68 Views
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Article
Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis
Srujan Kumar Gandham, Meghna Talekar, Amit Singh & Mansoor M Amiji
Pages: 4405-4423
Published online: 27 Feb 2023
AbstractforInhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis | Full Text | References | PDF (4 MB)
  • 97 Views
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Article
Controlling drug delivery kinetics from mesoporous titania thin films by pore size and surface energy
Johan Karlsson, Saba Atefyekta & Martin Andersson
Pages: 4425-4436
Published online: 27 Feb 2023
AbstractforControlling drug delivery kinetics from mesoporous titania thin films by pore size and surface energy | Full Text | References | PDF (3.4 MB)
  • 59 Views
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Article
Detection of gold nanorods uptake by macrophages using scattering analyses combined with diffusion reflection measurements as a potential tool for in vivo atherosclerosis tracking
Rinat Ankri, Susanne Melzer, Attila Tarnok & Dror Fixler
Pages: 4437-4446
Published online: 27 Feb 2023
AbstractforDetection of gold nanorods uptake by macrophages using scattering analyses combined with diffusion reflection measurements as a potential tool for in vivo atherosclerosis tracking | Full Text | References | PDF (1.7 MB)
  • 49 Views
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Article
Magnetically stimulated ciprofloxacin release from polymeric microspheres entrapping iron oxide nanoparticles
Sirinrath Sirivisoot & Benjamin S Harrison
Pages: 4447-4458
Published online: 27 Feb 2023
AbstractforMagnetically stimulated ciprofloxacin release from polymeric microspheres entrapping iron oxide nanoparticles | Full Text | References | PDF (4.1 MB)
  • 80 Views
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Article
Optimization, ex vivo permeation, and stability study of lipid nanocarrier loaded gelatin capsules for treatment of intermittent claudication
Marwa Ahmed Sallam & María Teresa Marín Boscá
Pages: 4459-4478
Published online: 27 Feb 2023
AbstractforOptimization, ex vivo permeation, and stability study of lipid nanocarrier loaded gelatin capsules for treatment of intermittent claudication | Full Text | References | PDF (4.1 MB)
  • 63 Views
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Article
Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer
Qingbing Wang, Jianfeng Li, Sai An, Yi Chen, Chen Jiang & Xiaolin Wang
Pages: 4479-4490
Published online: 27 Feb 2023
AbstractforMagnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer | Full Text | References | PDF (7.8 MB)
  • 62 Views
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Article
Respiratory syncytial virus-like nanoparticle vaccination induces long-term protection without pulmonary disease by modulating cytokines and T-cells partially through alveolar macrophages
Young-Tae Lee, Eun-Ju Ko, Hye Suk Hwang, Jong Seok Lee, Ki-Hye Kim, Young-Man Kwon & Sang-Moo Kang
Pages: 4491-4505
Published online: 27 Feb 2023
AbstractforRespiratory syncytial virus-like nanoparticle vaccination induces long-term protection without pulmonary disease by modulating cytokines and T-cells partially through alveolar macrophages | Full Text | References | PDF (3 MB)
  • 85 Views
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Article
Hyaluronic acid-functionalized single-walled carbon nanotubes as tumor-targeting MRI contrast agent
Lin Hou, Huijuan Zhang, Yating Wang, Lili Wang, Xiaomin Yang & Zhenzhong Zhang
Pages: 4507-4520
Published online: 16 Jul 2015
AbstractforHyaluronic acid-functionalized single-walled carbon nanotubes as tumor-targeting MRI contrast agent | Full Text | References | PDF (5.1 MB)
  • 63 Views
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Article
Significance of postgrowth processing of ZnO nanostructures on antibacterial activity against gram-positive and gram-negative bacteria
Shahid Mehmood, Malik A Rehman, Hammad Ismail, Bushra Mirza & Arshad S Bhatti
Pages: 4521-4533
Published online: 16 Jul 2015
AbstractforSignificance of postgrowth processing of ZnO nanostructures on antibacterial activity against gram-positive and gram-negative bacteria | Full Text | References | PDF (2.5 MB)
  • 71 Views
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Article
Targeted multidrug-resistance reversal in tumor based on PEG-PLL-PLGA polymer nano drug delivery system
Liting Guo, Haijun Zhang, Fei Wang, Ping Liu, Yonglu Wang, Guohua Xia, Ran Liu, Xueming Li, Haixiang Yin, Hulin Jiang & Baoan Chen
Pages: 4535-4547
Published online: 16 Jul 2015
AbstractforTargeted multidrug-resistance reversal in tumor based on PEG-PLL-PLGA polymer nano drug delivery system | Full Text | References | PDF (5.8 MB)
  • 107 Views
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Article
Effects of a micro/nano rough strontium-loaded surface on osseointegration
Yongfeng Li, Yaping Qi, Qi Gao, Qiang Niu, Mingming Shen, Qian Fu, Kaijin Hu & Liang Kong
Pages: 4549-4563
Published online: 27 Feb 2023
AbstractforEffects of a micro/nano rough strontium-loaded surface on osseointegration | Full Text | References | PDF (6.2 MB)
  • 53 Views
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Article
Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles
Muhammad Naeem, Jiafu Cao, Moonjeong Choi, Woo Seong Kim, Hyung Ryong Moon, Bok Luel Lee, Min-Soo Kim, Yunjin Jung & Jin-Wook Yoo
Pages: 4565-4580
Published online: 27 Feb 2023
AbstractforEnhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles | Full Text | References | PDF (5.6 MB)
  • 87 Views
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Article
Effect of liposomal fluidity on skin permeation of sodium fluorescein entrapped in liposomes
Thirapit Subongkot & Tanasait Ngawhirunpat
Pages: 4581-4592
Published online: 27 Feb 2023
AbstractforEffect of liposomal fluidity on skin permeation of sodium fluorescein entrapped in liposomes | Full Text | References | PDF (2.4 MB)
  • 88 Views
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Article
Increased osteoblast function in vitro and in vivo through surface nanostructuring by ultrasonic shot peening
Yongyuan Guo, Beibei Hu, Chu Tang, Yunpeng Wu, Pengfei Sun, Xianlong Zhang & Yuhua Jia
Pages: 4593-4603
Published online: 20 Jul 2015
AbstractforIncreased osteoblast function in vitro and in vivo through surface nanostructuring by ultrasonic shot peening | Full Text | References | PDF (3.8 MB)
  • 54 Views
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Article
Preparation and tumor cell model based biobehavioral evaluation of the nanocarrier system using partially reduced graphene oxide functionalized by surfactant
Yimin Wang, Kunping Liu, Zewei Luo & Yixiang Duan
Pages: 4605-4620
Published online: 20 Jul 2015
AbstractforPreparation and tumor cell model based biobehavioral evaluation of the nanocarrier system using partially reduced graphene oxide functionalized by surfactant | Full Text | References | PDF (5.9 MB)
  • 61 Views
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Erratum

Correction
Undetactable levels of genotoxicity of SiO2 nanoparticles in in vitro and in vivo tests [Erratum]
Page: 4621
Published online: 21 Jul 2015
CitationforUndetactable levels of genotoxicity of SiO2 nanoparticles in in vitro and in vivo tests [Erratum] | Full Text | PDF (91.9 KB)
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Original Research

Article
Immobilization of collagen peptide on dialdehyde bacterial cellulose nanofibers via covalent bonds for tissue engineering and regeneration
Xiaoxiao Wen, Yudong Zheng, Jian Wu, Lu-Ning Wang, Zhenya Yuan, Jiang Peng & Haoye Meng
Pages: 4623-4637
Published online: 21 Jul 2015
AbstractforImmobilization of collagen peptide on dialdehyde bacterial cellulose nanofibers via covalent bonds for tissue engineering and regeneration | Full Text | References | PDF (4.4 MB)
  • 130 Views
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Article
Study of magnetic silk fibroin nanoparticles for massage-like transdermal drug delivery
Ai-Zheng Chen, Lin-Qing Chen, Shi-Bin Wang, Ya-Qiong Wang & Jun-Zhe Zha
Pages: 4639-4651
Published online: 27 Feb 2023
AbstractforStudy of magnetic silk fibroin nanoparticles for massage-like transdermal drug delivery | Full Text | References | PDF (6.1 MB)
  • 144 Views
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Article
Styrene maleic acid micelles as a nanocarrier system for oral anticancer drug delivery – dual uptake through enterocytes and M-cells
Neha N Parayath, Hayley Nehoff, Philipp Müller, Sebastien Taurin & Khaled Greish
Pages: 4653-4667
Published online: 22 Jul 2015
AbstractforStyrene maleic acid micelles as a nanocarrier system for oral anticancer drug delivery – dual uptake through enterocytes and M-cells | Full Text | References | PDF (4.5 MB)
  • 74 Views
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Article
Reducible chimeric polypeptide consisting of octa-d-arginine and tetra-l-histidine peptides as an efficient gene delivery vector
Xiaoyu Wang, Zongguang Tai, Jing Tian, Wei Zhang, Chong Yao, Lijuan Zhang, Yuan Gao, Quangang Zhu, Jing Gao & Shen Gao
Pages: 4669-4690
Published online: 27 Feb 2023
AbstractforReducible chimeric polypeptide consisting of octa-d-arginine and tetra-l-histidine peptides as an efficient gene delivery vector | Full Text | References | PDF (9.3 MB)
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Article
Sustained co-delivery of BIO and IGF-1 by a novel hybrid hydrogel system to stimulate endogenous cardiac repair in myocardial infarcted rat hearts
Rui Fang, Shupei Qiao, Yi Liu, Qingyuan Meng, Xiongbiao Chen, Bing Song, Xiaolu Hou & Weiming Tian
Pages: 4691-4703
Published online: 28 Jul 2015
AbstractforSustained co-delivery of BIO and IGF-1 by a novel hybrid hydrogel system to stimulate endogenous cardiac repair in myocardial infarcted rat hearts | Full Text | References | PDF (4.7 MB)
  • 74 Views
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Article
Characterization of pulmonary protein profiles in response to zinc oxide nanoparticles in mice: a 24-hour and 28-day follow-up study
Chih-Hong Pan, Kai-Jen Chuang, Jen-Kun Chen, Ta-Chih Hsiao, Ching-Huang Lai, Tim P Jones, Kelly A BéruBé, Gui-Bing Hong, Kin-Fai Ho & Hsiao-Chi Chuang
Pages: 4705-4716
Published online: 27 Jul 2015
AbstractforCharacterization of pulmonary protein profiles in response to zinc oxide nanoparticles in mice: a 24-hour and 28-day follow-up study | Full Text | References | PDF (1.6 MB)
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Article
Controllable drug uptake and nongenomic response through estrogen-anchored cyclodextrin drug complex
Juan-Juan Yin, Stepan P Shumyak, Christopher Burgess, Zhi-Wei Zhou, Zhi-Xu He, Xue-Ji Zhang, Shu-Ting Pan, Tian-Xin Yang, Wei Duan, Jia-Xuan Qiu & Shu-Feng Zhou
Pages: 4717-4730
Published online: 27 Jul 2015
AbstractforControllable drug uptake and nongenomic response through estrogen-anchored cyclodextrin drug complex | Full Text | References | PDF (2.6 MB)
  • 43 Views
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Article
Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool
Mayara Klimuk Uchiyama, Sergio Hiroshi Toma, Stephen Fernandes Rodrigues, Ana Lucia Borges Shimada, Rodrigo Azevedo Loiola, Hernán Joel Cervantes Rodríguez, Pedro Vitoriano Oliveira, Maciel Santos Luz, Said Rahnamaye Rabbani, Henrique Eisi Toma, Sandra Helena Poliselli Farsky & Koiti Araki
Pages: 4731-4746
Published online: 28 Jul 2015
AbstractforUltrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool | Full Text | References | PDF (5.8 MB)
  • 78 Views
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Article
Gold nanorods/mesoporous silica-based nanocomposite as theranostic agents for targeting near-infrared imaging and photothermal therapy induced with laser
Yang Liu, Ming Xu, Qing Chen, Guannan Guan, Wen Hu, Xiuli Zhao, Mingxi Qiao, Haiyang Hu, Ying Liang, Heyun Zhu & Dawei Chen
Pages: 4747-4761
Published online: 28 Jul 2015
AbstractforGold nanorods/mesoporous silica-based nanocomposite as theranostic agents for targeting near-infrared imaging and photothermal therapy induced with laser | Full Text | References | PDF (5.7 MB)
  • 141 Views
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Article
Polycaprolactone/maltodextrin nanocarrier for intracellular drug delivery: formulation, uptake mechanism, internalization kinetics, and subcellular localization
Maxwell Korang-Yeboah, Yamini Gorantla, Simon A Paulos, Pankaj Sharma, Jaideep Chaudhary & Ravi Palaniappan
Pages: 4763-4781
Published online: 29 Jul 2015
AbstractforPolycaprolactone/maltodextrin nanocarrier for intracellular drug delivery: formulation, uptake mechanism, internalization kinetics, and subcellular localization | Full Text | References | PDF (8.2 MB)
  • 71 Views
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Article
Construction and characterization of an anti-CD20 mAb nanocomb with exceptionally excellent lymphoma-suppressing activity
Hua-Fei Li, Cong Wu, Ting Chen, Ge Zhang, He Zhao, Chang-Hong Ke & Zheng Xu
Pages: 4783-4796
Published online: 30 Jul 2015
AbstractforConstruction and characterization of an anti-CD20 mAb nanocomb with exceptionally excellent lymphoma-suppressing activity | Full Text | References | PDF (4.4 MB)
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Article
Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge
Gelareh Arzani, Azadeh Haeri, Marjan Daeihamed, Hamid Bakhtiari-Kaboutaraki & Simin Dadashzadeh
Pages: 4797-4813
Published online: 29 Jul 2015
AbstractforNiosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge | Full Text | References | PDF (3.5 MB)
  • 264 Views
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Article
A curcumin-loaded liquid crystal precursor mucoadhesive system for the treatment of vaginal candidiasis
Rafael Salmazi, Giovana Calixto, Jéssica Bernegossi, Matheus Aparecido dos Santos Ramos, Taís Maria Bauab & Marlus Chorilli
Pages: 4815-4824
Published online: 30 Jul 2015
AbstractforA curcumin-loaded liquid crystal precursor mucoadhesive system for the treatment of vaginal candidiasis | Full Text | References | PDF (1.1 MB)
  • 171 Views
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Article
Targeted delivery of chemically modified anti-miR-221 to hepatocellular carcinoma with negatively charged liposomes
Wendian Zhang, Fangqi Peng, Taotao Zhou, Yifei Huang, Li Zhang, Peng Ye, Miao Lu, Guang Yang, Yongkang Gai, Tan Yang, Xiang Ma & Guangya Xiang
Pages: 4825-4836
Published online: 29 Jul 2015
AbstractforTargeted delivery of chemically modified anti-miR-221 to hepatocellular carcinoma with negatively charged liposomes | Full Text | References | PDF (2.5 MB)
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Review

Review Article
Ongoing ethical issues concerning authorship in biomedical journals: an integrative review
Rachel Anne Kornhaber, Loyola M McLean & Rodney J Baber
Pages: 4837-4846
Published online: 30 Jul 2015
AbstractforOngoing ethical issues concerning authorship in biomedical journals: an integrative review | Full Text | References | PDF (361.3 KB)
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Original Research

Article
Numerical optimization of targeted delivery of charged nanoparticles to the ostiomeatal complex for treatment of rhinosinusitis
Jinxiang Xi, Jiayao Eddie Yuan, Xiuhua April Si & James Hasbany
Pages: 4847-4861
Published online: 30 Jul 2015
AbstractforNumerical optimization of targeted delivery of charged nanoparticles to the ostiomeatal complex for treatment of rhinosinusitis | Full Text | References | PDF (4.3 MB)
  • 59 Views
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Article
Dual-functional c(RGDyK)-decorated Pluronic micelles designed for antiangiogenesis and the treatment of drug-resistant tumor
Yanzuo Chen, Wei Zhang, Yukun Huang, Feng Gao & Xiaoling Fang
Pages: 4863-4881
Published online: 30 Jul 2015
AbstractforDual-functional c(RGDyK)-decorated Pluronic micelles designed for antiangiogenesis and the treatment of drug-resistant tumor | Full Text | References | PDF (4.7 MB)
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Article
The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface
Li Hui Tan, Peter H Sykes, Maan M Alkaisi & John J Evans
Pages: 4883-4895
Published online: 03 Aug 2015
AbstractforThe characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface | Full Text | References | PDF (3.2 MB)
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Letter

Letter
Small molecules against B-RAF (BRAF) Val600Glu (V600E) single mutation
Florin Zaharie, Roxana Cojocneanu-Petric, Mihai Muresan, Ioana Frinc, Delia Dima, Bobe Petrushev, Alina Tanase, Cristian Berce, Mariana Chitic, Ioana Berindan-Neagoe, Valentina Pileczki, Alexandru Irimie & Ciprian Tomuleasa
Pages: 4897-4899
Published online: 31 Jul 2015
First Page PreviewforSmall molecules against B-RAF (BRAF) Val600Glu (V600E) single mutation | Full Text | References | PDF (169.4 KB)
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Original Research

Article
Magnetic removal of Entamoeba cysts from water using chitosan oligosaccharide-coated iron oxide nanoparticles
Sudeep Shukla, Vikas Arora, Alka Jadaun, Jitender Kumar, Nishant Singh & Vinod Kumar Jain
Pages: 4901-4917
Published online: 31 Jul 2015
AbstractforMagnetic removal of Entamoeba cysts from water using chitosan oligosaccharide-coated iron oxide nanoparticles | Full Text | References | PDF (7.8 MB)
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Review

Review Article
Peptides and proteins used to enhance gold nanoparticle delivery to the brain: preclinical approaches
Carolina Velasco-Aguirre, Francisco Morales, Eduardo Gallardo-Toledo, Simon Guerrero, Ernest Giralt, Eyleen Araya & Marcelo J Kogan
Pages: 4919-4936
Published online: 10 Aug 2015
AbstractforPeptides and proteins used to enhance gold nanoparticle delivery to the brain: preclinical approaches | Full Text | References | PDF (2.5 MB)
  • 209 Views
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Original Research

Article
Nanoemulsions as novel oral carriers of stiripentol: insights into the protective effect and absorption enhancement
Rong Lu, Shan Liu, Qilin Wang & Xia Li
Pages: 4937-4946
Published online: 31 Jul 2015
AbstractforNanoemulsions as novel oral carriers of stiripentol: insights into the protective effect and absorption enhancement | Full Text | References | PDF (2.8 MB)
  • 119 Views
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Article
A novel strategy for the discrimination of gelatinous Chinese medicines based on enzymatic digestion followed by nano-flow liquid chromatography in tandem with orbitrap mass spectrum detection
Huan Yang, Yuping Shen, Ying Xu, Aida Serra Maqueda, Jie Zheng, Qinan Wu & James P Tam
Pages: 4947-4955
Published online: 05 Aug 2015
AbstractforA novel strategy for the discrimination of gelatinous Chinese medicines based on enzymatic digestion followed by nano-flow liquid chromatography in tandem with orbitrap mass spectrum detection | Full Text | References | PDF (1.5 MB)
  • 72 Views
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Article
Enhancement of radiotherapy by ceria nanoparticles modified with neogambogic acid in breast cancer cells
Feng Chen, Xiao Hong Zhang, Xiao Dan Hu, Wei Zhang, Zhi Chao Lou, Li Hua Xie, Pei Dang Liu & Hai Qian Zhang
Pages: 4957-4969
Published online: 14 Aug 2015
AbstractforEnhancement of radiotherapy by ceria nanoparticles modified with neogambogic acid in breast cancer cells | Full Text | References | PDF (3.8 MB)
  • 86 Views
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Article
Applicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use
Kozue Oana, Michiko Kobayashi, Dai Yamaki, Tsukasa Sakurada, Noriyuki Nagano & Yoshiyuki Kawakami
Pages: 4971-4979
Published online: 04 Aug 2015
AbstractforApplicability assessment of ceramic microbeads coated with hydroxyapatite-binding silver/titanium dioxide ceramic composite earthplus™ to the eradication of Legionella in rainwater storage tanks for household use | Full Text | References | PDF (1,014.2 KB)
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Review

Review Article
Nanotechnology-based drug delivery systems for the treatment of Alzheimer’s disease
Bruno Fonseca-Santos, Maria Palmira Daflon Gremião & Marlus Chorilli
Pages: 4981-5003
Published online: 04 Aug 2015
AbstractforNanotechnology-based drug delivery systems for the treatment of Alzheimer’s disease | Full Text | References | PDF (1.9 MB)
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Original Research

Article
Role of SIRT1-mediated mitochondrial and Akt pathways in glioblastoma cell death induced by Cotinus coggygria flavonoid nanoliposomes
Gang Wang, Jun Jie Wang, Tony SS To, Hua Fu Zhao & Jing Wang
Pages: 5005-5023
Published online: 04 Aug 2015
AbstractforRole of SIRT1-mediated mitochondrial and Akt pathways in glioblastoma cell death induced by Cotinus coggygria flavonoid nanoliposomes | Full Text | References | PDF (6.4 MB)
  • 87 Views
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Article
Silver-coated carbon nanotubes downregulate the expression of Pseudomonas aeruginosa virulence genes: a potential mechanism for their antimicrobial effect
Ejovwoke Dosunmu, Atul A Chaudhari, Shree R Singh, Vida A Dennis & Shreekumar R Pillai
Pages: 5025-5034
Published online: 05 Aug 2015
AbstractforSilver-coated carbon nanotubes downregulate the expression of Pseudomonas aeruginosa virulence genes: a potential mechanism for their antimicrobial effect | Full Text | References | PDF (2.2 MB)
  • 103 Views
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Article
pH-Responsive therapeutic solid lipid nanoparticles for reducing P-glycoprotein-mediated drug efflux of multidrug resistant cancer cells
Hsin-Hung Chen, Wen-Chia Huang, Wen-Hsuan Chiang, Te-I Liu, Ming-Yin Shen, Yuan-Hung Hsu, Sung-Chyr Lin & Hsin-Cheng Chiu
Pages: 5035-5048
Published online: 05 Aug 2015
AbstractforpH-Responsive therapeutic solid lipid nanoparticles for reducing P-glycoprotein-mediated drug efflux of multidrug resistant cancer cells | Full Text | References | PDF (5.5 MB)
  • 132 Views
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Article
Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice
Mei Xue, Liang Zhang, Ming-xing Yang, Wei Zhang, Xiu-min Li, Zhi-min Ou, Zhi-peng Li, Su-huan Liu, Xue-jun Li & Shu-yu Yang
Pages: 5049-5057
Published online: 06 Aug 2015
AbstractforBerberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice | Full Text | References | PDF (2.3 MB)
  • 160 Views
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Article
Inhibition of lung cancer cells A549 and H460 by curcuminoid extracts and nanoemulsions prepared from Curcuma longa Linnaeus
Hong-Bin Chang & Bing-Huei Chen
Pages: 5059-5080
Published online: 06 Aug 2015
AbstractforInhibition of lung cancer cells A549 and H460 by curcuminoid extracts and nanoemulsions prepared from Curcuma longa Linnaeus | Full Text | References | PDF (6.3 MB)
  • 194 Views
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Article
Nanostructured lipid system as a strategy to improve the anti-Candida albicans activity of Astronium sp.
Bruna Vidal Bonifácio, Matheus Aparecido dos Santos Ramos, Patrícia Bento da Silva, Kamila Maria Silveira Negri, Érica de Oliveira Lopes, Leonardo Perez de Souza, Wagner Vilegas, Fernando Rogério Pavan, Marlus Chorilli & Taís Maria Bauab
Pages: 5081-5092
Published online: 10 Aug 2015
AbstractforNanostructured lipid system as a strategy to improve the anti-Candida albicans activity of Astronium sp. | Full Text | References | PDF (1.1 MB)
  • 122 Views
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Article
Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage
Mariele Feiffer Charão, Caroline Souto, Natália Brucker, Anelise Barth, Denise S Jornada, Daiandra Fagundez, Daiana Silva Ávila, Vera L Eifler-Lima, Silvia S Guterres, Adriana R Pohlmann & Solange Cristina Garcia
Pages: 5093-5106
Published online: 10 Aug 2015
AbstractforCaenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage | Full Text | References | PDF (1.9 MB)
  • 143 Views
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Article
Pharmacological characterization of nanoparticle-induced platelet microaggregation using quartz crystal microbalance with dissipation: comparison with light aggregometry
Maria J Santos-Martinez, Krzysztof A Tomaszewski, Carlos Medina, Despina Bazou, John F Gilmer & Marek W Radomski
Pages: 5107-5119
Published online: 13 Aug 2015
AbstractforPharmacological characterization of nanoparticle-induced platelet microaggregation using quartz crystal microbalance with dissipation: comparison with light aggregometry | Full Text | References | PDF (5.7 MB)
  • 57 Views
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Corrigendum

Correction
Adherence ability of Staphylococcus epidermidis on prosthetic biomaterials: an in vitro study [Corrigendum]
Page: 5121
Published online: 12 Aug 2015
CitationforAdherence ability of Staphylococcus epidermidis on prosthetic biomaterials: an in vitro study [Corrigendum] | Full Text | PDF (104 KB)
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Original Research

Article
Lactoferrin-modified PEGylated liposomes loaded with doxorubicin for targeting delivery to hepatocellular carcinoma
Minyan Wei, Xiucai Guo, Liuxiao Tu, Qi Zou, Qi Li, Chenyi Tang, Bao Chen, Yuehong Xu & Chuanbin Wu
Pages: 5123-5137
Published online: 12 Aug 2015
AbstractforLactoferrin-modified PEGylated liposomes loaded with doxorubicin for targeting delivery to hepatocellular carcinoma | Full Text | References | PDF (3.2 MB)
  • 135 Views
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Review

Review Article
Nanotechnology for treating osteoporotic vertebral fractures
Chunxia Gao, Donglei Wei, Huilin Yang, Tao Chen & Lei Yang
Pages: 5139-5157
Published online: 13 Aug 2015
AbstractforNanotechnology for treating osteoporotic vertebral fractures | Full Text | References | PDF (4.7 MB)
  • 161 Views
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Original Research

Article
Association of electrospinning with electrospraying: a strategy to produce 3D scaffolds with incorporated stem cells for use in tissue engineering
Daikelly Iglesias Braghirolli, Fernanda Zamboni, Gerson AX Acasigua & Patricia Pranke
Pages: 5159-5170
Published online: 14 Aug 2015
AbstractforAssociation of electrospinning with electrospraying: a strategy to produce 3D scaffolds with incorporated stem cells for use in tissue engineering | Full Text | References | PDF (4 MB)
  • 78 Views
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Article
Fiber-optic triggered release of liposome in vivo: implication of personalized chemotherapy
Huei-Ling Huang, Pei-Hsuan Lu, Hung-Chih Yang, Gi-Da Lee, Han-Ru Li & Kuo-Chih Liao
Pages: 5171-5185
Published online: 14 Aug 2015
AbstractforFiber-optic triggered release of liposome in vivo: implication of personalized chemotherapy | Full Text | References | PDF (5 MB)
  • 76 Views
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Article
In vitro study of novel gadolinium-loaded liposomes guided by GBI-10 aptamer for promising tumor targeting and tumor diagnosis by magnetic resonance imaging
Meng-Jie Gu, Kun-Feng Li, Lan-Xin Zhang, Huan Wang, Li-Si Liu, Zhuo-Zhao Zheng, Nan-Yin Han, Zhen-Jun Yang & Tian-Yuan Fan
Pages: 5187-5204
Published online: 17 Aug 2015
AbstractforIn vitro study of novel gadolinium-loaded liposomes guided by GBI-10 aptamer for promising tumor targeting and tumor diagnosis by magnetic resonance imaging | Full Text | References | PDF (3.2 MB)
  • 103 Views
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Article
Codelivery of SH-aspirin and curcumin by mPEG-PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis
Lin Zhou, Xingmei Duan, Shi Zeng, Ke Men, Xueyan Zhang, Li Yang & Xiang Li
Pages: 5205-5218
Published online: 18 Aug 2015
AbstractforCodelivery of SH-aspirin and curcumin by mPEG-PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis | Full Text | References | PDF (3.6 MB)
  • 88 Views
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Article
D-α-tocopherol polyethylene glycol succinate-based derivative nanoparticles as a novel carrier for paclitaxel delivery
Yupei Wu, Qian Chu, Songwei Tan, Xiangting Zhuang, Yuling Bao, Tingting Wu & Zhiping Zhang
Pages: 5219-5235
Published online: 20 Aug 2015
AbstractforD-α-tocopherol polyethylene glycol succinate-based derivative nanoparticles as a novel carrier for paclitaxel delivery | Full Text | References | PDF (8.5 MB)
  • 71 Views
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Article
Real-time analysis of dual-display phage immobilization and autoantibody screening using quartz crystal microbalance with dissipation monitoring
Kaushik Rajaram, Patricia Losada-Pérez, Veronique Vermeeren, Baharak Hosseinkhani, Patrick Wagner, Veerle Somers & Luc Michiels
Pages: 5237-5247
Published online: 19 Aug 2015
AbstractforReal-time analysis of dual-display phage immobilization and autoantibody screening using quartz crystal microbalance with dissipation monitoring | Full Text | References | PDF (2.2 MB)
  • 50 Views
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Article
Tumor-targeting, pH-sensitive nanoparticles for docetaxel delivery to drug-resistant cancer cells
Tuan Hiep Tran, Thiruganesh Ramasamy, Ju Yeon Choi, Hanh Thuy Nguyen, Thanh Tung Pham, Jee-Heon Jeong, Sae Kwang Ku, Han-Gon Choi, Chul Soon Yong & Jong Oh Kim
Pages: 5249-5262
Published online: 21 Aug 2015
AbstractforTumor-targeting, pH-sensitive nanoparticles for docetaxel delivery to drug-resistant cancer cells | Full Text | References | PDF (4.4 MB)
  • 129 Views
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Article
Cationic PLGA/Eudragit RL nanoparticles for increasing retention time in synovial cavity after intra-articular injection in knee joint
Sung Rae Kim, Myoung Jin Ho, Eugene Lee, Joon Woo Lee, Young Wook Choi & Myung Joo Kang
Pages: 5263-5271
Published online: 24 Aug 2015
AbstractforCationic PLGA/Eudragit RL nanoparticles for increasing retention time in synovial cavity after intra-articular injection in knee joint | Full Text | References | PDF (1.4 MB)
  • 148 Views
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Article
Small molecule PZL318: forming fluorescent nanoparticles capable of tracing their interactions with cancer cells and activated platelets, slowing tumor growth and inhibiting thrombosis
Shan Li, Yuji Wang, Feng Wang, Yaonan Wang, Xiaoyi Zhang, Ming Zhao, Qiqi Feng, Jianhui Wu, Shurui Zhao, Wei Wu & Shiqi Peng
Pages: 5273-5292
Published online: 27 Feb 2023
AbstractforSmall molecule PZL318: forming fluorescent nanoparticles capable of tracing their interactions with cancer cells and activated platelets, slowing tumor growth and inhibiting thrombosis | Full Text | References | PDF (4.3 MB)
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Article
Increased NIH 3T3 fibroblast functions on cell culture dishes which mimic the nanometer fibers of natural tissues
Garima Bhardwaj & Thomas J Webster
Pages: 5293-5299
Published online: 24 Aug 2015
AbstractforIncreased NIH 3T3 fibroblast functions on cell culture dishes which mimic the nanometer fibers of natural tissues | Full Text | References | PDF (2.1 MB)
  • 56 Views
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Article
The effect of aspirin nanoemulsion on TNFα and iNOS in gastric tissue in comparison with conventional aspirin
Fatma Abd Elhalim Mahmoud, Khalid S Hashem & Asmaa Mohammed M Hussein Elkelawy
Pages: 5301-5308
Published online: 24 Aug 2015
AbstractforThe effect of aspirin nanoemulsion on TNFα and iNOS in gastric tissue in comparison with conventional aspirin | Full Text | References | PDF (3 MB)
  • 81 Views
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Article
Effects of X-shaped reduction-sensitive amphiphilic block copolymer on drug delivery
Haijun Xiao & Lu Wang
Pages: 5309-5325
Published online: 27 Feb 2023
AbstractforEffects of X-shaped reduction-sensitive amphiphilic block copolymer on drug delivery | Full Text | References | PDF (3.4 MB)
  • 55 Views
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Article
Dual actions of albumin packaging and tumor targeting enhance the antitumor efficacy and reduce the cardiotoxicity of doxorubicin in vivo
Ke Zheng, Rui Li, Xiaolei Zhou, Ping Hu, Yaxin Zhang, Yunmei Huang, Zhuo Chen & Mingdong Huang
Pages: 5327-5342
Published online: 24 Aug 2015
AbstractforDual actions of albumin packaging and tumor targeting enhance the antitumor efficacy and reduce the cardiotoxicity of doxorubicin in vivo | Full Text | References | PDF (5.4 MB)
  • 64 Views
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Article
Polyethyleneimine-functionalized boron nitride nanospheres as efficient carriers for enhancing the immunostimulatory effect of CpG oligodeoxynucleotides
Huijie Zhang, Shini Feng, Ting Yan, Chunyi Zhi, Xiao-Dong Gao & Nobutaka Hanagata
Pages: 5343-5353
Published online: 24 Aug 2015
AbstractforPolyethyleneimine-functionalized boron nitride nanospheres as efficient carriers for enhancing the immunostimulatory effect of CpG oligodeoxynucleotides | Full Text | References | PDF (2.1 MB)
  • 67 Views
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Article
Evolution of availability of curcumin inside poly-lactic-co-glycolic acid nanoparticles: impact on antioxidant and antinitrosant properties
Didier Betbeder, Emmanuelle Lipka, Mike Howsam & Rodolphe Carpentier
Pages: 5355-5366
Published online: 26 Aug 2015
AbstractforEvolution of availability of curcumin inside poly-lactic-co-glycolic acid nanoparticles: impact on antioxidant and antinitrosant properties | Full Text | References | PDF (1.3 MB)
  • 89 Views
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Article
Influence of cationic lipid concentration on properties of lipid–polymer hybrid nanospheres for gene delivery
Rajendran JC Bose, Yoshie Arai, Jong Chan Ahn, Hansoo Park & Soo-Hong Lee
Pages: 5367-5382
Published online: 02 Sep 2015
AbstractforInfluence of cationic lipid concentration on properties of lipid–polymer hybrid nanospheres for gene delivery | Full Text | References | PDF (5.3 MB)
  • 86 Views
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Article
Spray-dried powders enhance vaginal siRNA delivery by potentially modulating the mucus molecular sieve structure
Na Wu, Xinxin Zhang, Feifei Li, Tao Zhang, Yong Gan & Juan Li
Pages: 5383-5396
Published online: 26 Aug 2015
AbstractforSpray-dried powders enhance vaginal siRNA delivery by potentially modulating the mucus molecular sieve structure | Full Text | References | PDF (5 MB)
  • 69 Views
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Article
Modification of paclitaxel-loaded solid lipid nanoparticles with 2-hydroxypropyl-β-cyclodextrin enhances absorption and reduces nephrotoxicity associated with intravenous injection
Jong-Suep Baek, Ju-Heon Kim, Jeong-Sook Park & Cheong-Weon Cho
Pages: 5397-5405
Published online: 26 Aug 2015
AbstractforModification of paclitaxel-loaded solid lipid nanoparticles with 2-hydroxypropyl-β-cyclodextrin enhances absorption and reduces nephrotoxicity associated with intravenous injection | Full Text | References | PDF (3.5 MB)
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Review

Review Article
Molecular targets in arthritis and recent trends in nanotherapy
Kislay Roy, Rupinder Kaur Kanwar & Jagat Rakesh Kanwar
Pages: 5407-5420
Published online: 27 Feb 2023
AbstractforMolecular targets in arthritis and recent trends in nanotherapy | Full Text | References | PDF (2.7 MB)
  • 99 Views
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Corrigendum

Correction
Role of lipegfilgrastim in the management of chemotherapy-induced neutropenia [Corrigendum]
Page: 5421
Published online: 27 Aug 2015
CitationforRole of lipegfilgrastim in the management of chemotherapy-induced neutropenia [Corrigendum] | Full Text | PDF (103.2 KB)
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Original Research

Article
Identification of a cell-penetrating peptide domain from human beta-defensin 3 and characterization of its anti-inflammatory activity
Jue Yeon Lee, Jin Sook Suh, Jung Min Kim, Jeong Hwa Kim, Hyun Jung Park, Yoon Jeong Park & Chong Pyoung Chung
Pages: 5423-5434
Published online: 26 Aug 2015
AbstractforIdentification of a cell-penetrating peptide domain from human beta-defensin 3 and characterization of its anti-inflammatory activity | Full Text | References | PDF (2.6 MB)
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Article
Photothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus–ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor
Lucian Mocan, Cristian Matea, Flaviu A Tabaran, Ofelia Mosteanu, Teodora Pop, Teodora Mocan & Cornel Iancu
Pages: 5435-5445
Published online: 26 Aug 2015
AbstractforPhotothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus–ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor | Full Text | References | PDF (2.9 MB)
  • 105 Views
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Article
Enhanced delivery of PEAL nanoparticles with ultrasound targeted microbubble destruction mediated siRNA transfection in human MCF-7/S and MCF-7/ADR cells in vitro
Yanwei Teng, Min Bai, Ying Sun, Qi Wang, Fan Li, Jinfang Xing, Lianfang Du, Tao Gong & Yourong Duan
Pages: 5447-5457
Published online: 27 Aug 2015
AbstractforEnhanced delivery of PEAL nanoparticles with ultrasound targeted microbubble destruction mediated siRNA transfection in human MCF-7/S and MCF-7/ADR cells in vitro | Full Text | References | PDF (3.9 MB)
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Article
Novel piperine-loaded Tween-integrated monoolein cubosomes as brain-targeted oral nanomedicine in Alzheimer’s disease: pharmaceutical, biological, and toxicological studies
Yosra SR Elnaggar, Samar M Etman, Doaa A Abdelmonsif & Ossama Y Abdallah
Pages: 5459-5473
Published online: 27 Aug 2015
AbstractforNovel piperine-loaded Tween-integrated monoolein cubosomes as brain-targeted oral nanomedicine in Alzheimer’s disease: pharmaceutical, biological, and toxicological studies | Full Text | References | PDF (1.5 MB)
  • 405 Views
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Article
Synthesis, characterization, and in vitro evaluation of curcumin-loaded albumin nanoparticles surface-functionalized with glycyrrhetinic acid
Jingjing Li, Tong Chen, Feng Deng, Jingyuan Wan, Yalan Tang, Pei Yuan & Liangke Zhang
Pages: 5475-5487
Published online: 27 Aug 2015
AbstractforSynthesis, characterization, and in vitro evaluation of curcumin-loaded albumin nanoparticles surface-functionalized with glycyrrhetinic acid | Full Text | References | PDF (3.7 MB)
  • 124 Views
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Article
Enzyme-responsive doxorubicin release from dendrimer nanoparticles for anticancer drug delivery
Sang Joon Lee, Young-Il Jeong, Hyung-Kyu Park, Dae Hwan Kang, Jong-Suk Oh, Sam-Gyu Lee & Hyun Chul Lee
Pages: 5489-5503
Published online: 27 Feb 2023
AbstractforEnzyme-responsive doxorubicin release from dendrimer nanoparticles for anticancer drug delivery | Full Text | References | PDF (3.1 MB)
  • 145 Views
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Article
Apoptosis and necrosis induced by novel realgar quantum dots in human endometrial cancer cells via endoplasmic reticulum stress signaling pathway
Huan Wang, Zhengyun Liu, Ying Gou, Yu Qin, Yaze Xu, Jie Liu & Jin-Zhu Wu
Pages: 5505-5512
Published online: 31 Aug 2015
AbstractforApoptosis and necrosis induced by novel realgar quantum dots in human endometrial cancer cells via endoplasmic reticulum stress signaling pathway | Full Text | References | PDF (2.3 MB)
  • 81 Views
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Article
Carcinogenic activity of PbS quantum dots screened using exosomal biomarkers secreted from HEK293 cells
Jung-Hee Kim, Hye-Rim Kim, Bo-Ram Lee, Eun-Sook Choi, Su-Il In & Eunjoo Kim
Pages: 5513-5528
Published online: 27 Feb 2023
AbstractforCarcinogenic activity of PbS quantum dots screened using exosomal biomarkers secreted from HEK293 cells | Full Text | References | PDF (2.6 MB)
  • 79 Views
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Article
Nanoemulsions containing a synthetic chalcone as an alternative for treating cutaneous leshmaniasis: optimization using a full factorial design
Cristiane Bastos de Mattos, Débora Fretes Argenta, Gabriela de Lima Melchiades, Marlon Norberto Sechini Cordeiro, Maiko Luis Tonini, Milene Hoehr Moraes, Tanara Beatriz Weber, Silvane Souza Roman, Ricardo José Nunes, Helder Ferreira Teixeira, Mário Steindel & Letícia Scherer Koester
Pages: 5529-5542
Published online: 01 Sep 2015
AbstractforNanoemulsions containing a synthetic chalcone as an alternative for treating cutaneous leshmaniasis: optimization using a full factorial design | Full Text | References | PDF (3.6 MB)
  • 157 Views
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Review

Review Article
Pre- and postmortem imaging of transplanted cells
Anna Andrzejewska, Adam Nowakowski, Miroslaw Janowski, Jeff WM Bulte, Assaf A Gilad, Piotr Walczak & Barbara Lukomska
Pages: 5543-5559
Published online: 02 Sep 2015
AbstractforPre- and postmortem imaging of transplanted cells | Full Text | References | PDF (2.8 MB)
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Original Research

Article
Cross talk between poly(ADP-ribose) polymerase 1 methylation and oxidative stress involved in the toxic effect of anatase titanium dioxide nanoparticles
Wenlin Bai, Yujiao Chen & Ai Gao
Pages: 5561-5569
Published online: 01 Sep 2015
AbstractforCross talk between poly(ADP-ribose) polymerase 1 methylation and oxidative stress involved in the toxic effect of anatase titanium dioxide nanoparticles | Full Text | References | PDF (1.4 MB)
  • 68 Views
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Article
Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy
Lingling Shan, Ming Liu, Chao Wu, Liang Zhao, Siwen Li, Lisheng Xu, Wengen Cao, Guizhen Gao & Yueqing Gu
Pages: 5571-5591
Published online: 01 Sep 2015
AbstractforMulti-small molecule conjugations as new targeted delivery carriers for tumor therapy | Full Text | References | PDF (5.5 MB)
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Letter

Letter
Potential toxicity of dental nanomaterials to the central nervous system
Davi Fontoura Solla, Tatiana Saito Paiva, Marcia André & Wellingson Silva Paiva
Pages: 5593-5596
Published online: 03 Sep 2015
First Page PreviewforPotential toxicity of dental nanomaterials to the central nervous system | Full Text | References | PDF (194.5 KB)
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Original Research

Article
Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement
Xiaoyue Zhou, Shin-Hye Park, Hongli Mao, Takashi Isoshima, Yi Wang & Yoshihiro Ito
Pages: 5597-5607
Published online: 02 Sep 2015
AbstractforNanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement | Full Text | References | PDF (3.3 MB)
  • 53 Views
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Review

Review Article
Inorganic nanolayers: structure, preparation, and biomedical applications
Bullo Saifullah & Mohd Zobir B Hussein
Pages: 5609-5633
Published online: 02 Sep 2015
AbstractforInorganic nanolayers: structure, preparation, and biomedical applications | Full Text | References | PDF (2.4 MB)
  • 144 Views
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Original Research

Article
Cationic polyelectrolyte-mediated delivery of antisense morpholino oligonucleotides for exon-skipping in vitro and in mdx mice
Mingxing Wang, Bo Wu, Jason D Tucker, Peijuan Lu & Qilong Lu
Pages: 5635-5646
Published online: 03 Sep 2015
AbstractforCationic polyelectrolyte-mediated delivery of antisense morpholino oligonucleotides for exon-skipping in vitro and in mdx mice | Full Text | References | PDF (6.3 MB)
  • 62 Views
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Article
Different patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimer and its biotin–pyridoxal bioconjugate BC-PAMAM in normal and cancer cells in vitro
Łukasz Uram, Magdalena Szuster, Aleksandra Filipowicz, Krzysztof Gargasz, Stanisław Wołowiec & Elżbieta Wałajtys-Rode
Pages: 5647-5661
Published online: 04 Sep 2015
AbstractforDifferent patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimer and its biotin–pyridoxal bioconjugate BC-PAMAM in normal and cancer cells in vitro | Full Text | References | PDF (7.1 MB)
  • 75 Views
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Article
Free radical scavenging in vitro and biological activity of diphenyl diselenide-loaded nanocapsules: DPDS-NCS antioxidant and toxicological effects
Sílvio Terra Stefanello, Fernando Dobrachinski, Nélson Rodrigues de Carvalho, Guilherme Pires Amaral, Rômulo Pillon Barcelos, Vitor Antunes Oliveira, Cláudia Sirlene Oliveira, Camila Ferrazza Alves Giordani, Maria Ester Pereira, Oscar Endrigo Dorneles Rodrigues & Félix Alexandre Antunes Soares
Pages: 5663-5670
Published online: 04 Sep 2015
AbstractforFree radical scavenging in vitro and biological activity of diphenyl diselenide-loaded nanocapsules: DPDS-NCS antioxidant and toxicological effects | Full Text | References | PDF (855.9 KB)
  • 68 Views
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Article
Tetracycline-grafted PLGA nanoparticles as bone-targeting drug delivery system
Hua Wang, Jun Liu, Shan Tao, Guihong Chai, Jianwei Wang, Fu-Qiang Hu & Hong Yuan
Pages: 5671-5685
Published online: 08 Sep 2015
AbstractforTetracycline-grafted PLGA nanoparticles as bone-targeting drug delivery system | Full Text | References | PDF (3 MB)
  • 183 Views
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Article
Imaging of Hsp70-positive tumors with cmHsp70.1 antibody-conjugated gold nanoparticles
Mathias K Gehrmann, Melanie A Kimm, Stefan Stangl, Thomas E Schmid, Peter B Noël, Ernst J Rummeny & Gabriele Multhoff
Pages: 5687-5700
Published online: 08 Sep 2015
AbstractforImaging of Hsp70-positive tumors with cmHsp70.1 antibody-conjugated gold nanoparticles | Full Text | References | PDF (3.8 MB)
  • 93 Views
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Review

Review Article
Biomimetics: forecasting the future of science, engineering, and medicine
Jangsun Hwang, Yoon Jeong, Jeong Min Park, Kwan Hong Lee, Jong Wook Hong & Jonghoon Choi
Pages: 5701-5713
Published online: 08 Sep 2015
AbstractforBiomimetics: forecasting the future of science, engineering, and medicine | Full Text | References | PDF (5.1 MB)
  • 1208 Views
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Original Research

Article
Delivery of DNAzyme targeting aurora kinase A to inhibit the proliferation and migration of human prostate cancer
Zhen Xing, Sai Gao, Yan Duan, Haobo Han, Li Li, Yan Yang & Quanshun Li
Pages: 5715-5727
Published online: 09 Sep 2015
AbstractforDelivery of DNAzyme targeting aurora kinase A to inhibit the proliferation and migration of human prostate cancer | Full Text | References | PDF (4.8 MB)
  • 83 Views
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Article
Targeting delivery of Radix Ophiopogonis polysaccharide to ischemic/reperfused rat myocardium by long-circulating macromolecular and liposomal carriers
LiNa Wang, ChunXia Yao, Fei Wu, Xiao Lin, Lan Shen & Yi Feng
Pages: 5729-5737
Published online: 10 Sep 2015
AbstractforTargeting delivery of Radix Ophiopogonis polysaccharide to ischemic/reperfused rat myocardium by long-circulating macromolecular and liposomal carriers | Full Text | References | PDF (1.1 MB)
  • 45 Views
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Article
Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles
Mohamed Qasim Al-Fahdawi, Abdullah Rasedee, Mothanna Sadiq Al-Qubaisi, Fatah H Alhassan, Rozita Rosli, Mohamed Ezzat El Zowalaty, Seïf-Eddine Naadja, Thomas J Webster & Yun Hin Taufiq-Yap
Pages: 5739-5750
Published online: 10 Sep 2015
AbstractforCytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles | Full Text | References | PDF (2.6 MB)
  • 92 Views
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Article
Endothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury
Shouqin Tian, Duanwen Cao, Haijuan Zou, Feng Bai, Zhongjuan Wang, Shirong Pan & Min Feng
Pages: 5751-5768
Published online: 10 Sep 2015
AbstractforEndothelial cell-targeted pVEGF165 polyplex plays a pivotal role in inhibiting intimal thickening after vascular injury | Full Text | References | PDF (8.3 MB)
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Corrigendum

Correction
Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines – in vitro studies [Corrigendum]
Page: 5769
Published online: 14 Sep 2015
CitationforAnacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines – in vitro studies [Corrigendum] | Full Text | PDF (95.3 KB)
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Original Research

Article
Synthesis and characterization of multifunctional hybrid-polymeric nanoparticles for drug delivery and multimodal imaging of cancer
Danny Jian Hang Tng, Peiyi Song, Guimiao Lin, Alana Mauluidy Soehartono, Guang Yang, Chengbin Yang, Feng Yin, Cher Heng Tan & Ken-Tye Yong
Pages: 5771-5786
Published online: 15 Sep 2015
AbstractforSynthesis and characterization of multifunctional hybrid-polymeric nanoparticles for drug delivery and multimodal imaging of cancer | Full Text | References | PDF (3.5 MB)
  • 74 Views
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Article
Hepatotoxicity assessment of Mn-doped ZnS quantum dots after repeated administration in mice
Yanjie Yang, Shuang-Yu Lv, Bianfei Yu, Shuang Xu, Jianmin Shen, Tong Zhao & Haixia Zhang
Pages: 5787-5796
Published online: 15 Sep 2015
AbstractforHepatotoxicity assessment of Mn-doped ZnS quantum dots after repeated administration in mice | Full Text | References | PDF (4.6 MB)
  • 51 Views
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Article
Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers
Abdel-Rahim M El-Helw & Usama A Fahmy
Pages: 5797-5804
Published online: 16 Sep 2015
AbstractforImprovement of fluvastatin bioavailability by loading on nanostructured lipid carriers | Full Text | References | PDF (895.7 KB)
  • 123 Views
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Article
Novel lactoferrin-conjugated amphiphilic poly(aminoethyl ethylene phosphate)/poly(L-lactide) copolymer nanobubbles for tumor-targeting ultrasonic imaging
Binhua Luo, Huageng Liang, Shengwei Zhang, Xiaojuan Qin, Xuhan Liu, Wei Liu, Fuqing Zeng, Yun Wu & Xiangliang Yang
Pages: 5805-5817
Published online: 27 Feb 2023
AbstractforNovel lactoferrin-conjugated amphiphilic poly(aminoethyl ethylene phosphate)/poly(L-lactide) copolymer nanobubbles for tumor-targeting ultrasonic imaging | Full Text | References | PDF (2.6 MB)
  • 57 Views
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Article
Preparation and characterization of anti-HIV nanodrug targeted to microfold cell of gut-associated lymphoid tissue
Upal Roy, Hong Ding, Sudheesh Pilakka-Kanthikeel, Andrea D Raymond, Venkata Atluri, Adriana Yndart, Elena M Kaftanovskaya, Elena Batrakova, Marisela Agudelo & Madhavan Nair
Pages: 5819-5835
Published online: 27 Feb 2023
AbstractforPreparation and characterization of anti-HIV nanodrug targeted to microfold cell of gut-associated lymphoid tissue | Full Text | References | PDF (2.9 MB)
  • 127 Views
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Article
Development, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes
Andreia Ascenso, Sara Raposo, Cátia Batista, Pedro Cardoso, Tiago Mendes, Fabíola Garcia Praça, Maria Vitória Lopes Badra Bentley & Sandra Simões
Pages: 5837-5851
Published online: 18 Sep 2015
AbstractforDevelopment, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes | Full Text | References | PDF (2.2 MB)
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Article
Neurite outgrowth stimulatory effects of myco synthesized AuNPs from Hericium erinaceus (Bull.: Fr.) Pers. on pheochromocytoma (PC-12) cells
Jegadeesh Raman, Hariprasath Lakshmanan, Priscilla A John, Chan Zhijian, Vengadesh Periasamy, Pamela David, Murali Naidu & Vikineswary Sabaratnam
Pages: 5853-5863
Published online: 18 Sep 2015
AbstractforNeurite outgrowth stimulatory effects of myco synthesized AuNPs from Hericium erinaceus (Bull.: Fr.) Pers. on pheochromocytoma (PC-12) cells | Full Text | References | PDF (2.5 MB)
  • 126 Views
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Article
Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation
Marlene A Lopes, Bárbara Abrahim-Vieira, Claudia Oliveira, Pedro Fonte, Alessandra M T Souza, Tammy Lira, Joana A D Sequeira, Carlos R Rodrigues, Lúcio M Cabral, Bruno Sarmento, Raquel Seiça, Francisco Veiga & António J Ribeiro
Pages: 5865-5880
Published online: 18 Sep 2015
AbstractforProbing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation | Full Text | References | PDF (1.4 MB)
  • 88 Views
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Article
Simvastatin enhances Rho/actin/cell rigidity pathway contributing to mesenchymal stem cells’ osteogenic differentiation
I-Chun Tai, Yao-Hsien Wang, Chung-Hwan Chen, Shu-Chun Chuang, Je-Ken Chang & Mei-Ling Ho
Pages: 5881-5894
Published online: 27 Feb 2023
AbstractforSimvastatin enhances Rho/actin/cell rigidity pathway contributing to mesenchymal stem cells’ osteogenic differentiation | Full Text | References | PDF (5 MB)
  • 61 Views
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Article
Synthesis and in vivo magnetic resonance imaging evaluation of biocompatible branched copolymer nanocontrast agents
Alexander W Jackson, Prashant Chandrasekharan, Jian Shi, Steven P Rannard, Quan Liu, Chang-Tong Yang & Tao He
Pages: 5895-5907
Published online: 18 Sep 2015
AbstractforSynthesis and in vivo magnetic resonance imaging evaluation of biocompatible branched copolymer nanocontrast agents | Full Text | References | PDF (2.6 MB)
  • 61 Views
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Article
Microwave-assisted fibrous decoration of mPE surface utilizing Aloe vera extract for tissue engineering applications
Arunpandian Balaji, Saravana Kumar Jaganathan, Eko Supriyanto, Ida Idayu Muhamad & Ahmad Zahran Md Khudzari
Pages: 5909-5923
Published online: 18 Sep 2015
AbstractforMicrowave-assisted fibrous decoration of mPE surface utilizing Aloe vera extract for tissue engineering applications | Full Text | References | PDF (15 MB)
  • 79 Views
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Article
Gold nanoparticles induce heme oxygenase-1 expression through Nrf2 activation and Bach1 export in human vascular endothelial cells
Tsung-Hsuan Lai, Jiunn-Min Shieh, Chih-Jen Tsou & Wen-Bin Wu
Pages: 5925-5939
Published online: 21 Sep 2015
AbstractforGold nanoparticles induce heme oxygenase-1 expression through Nrf2 activation and Bach1 export in human vascular endothelial cells | Full Text | References | PDF (3 MB)
  • 93 Views
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Article
Chitosan nanofiber scaffold improves bone healing via stimulating trabecular bone production due to upregulation of the Runx2/osteocalcin/alkaline phosphatase signaling pathway
Ming-Hua Ho, Chih-Jung Yao, Mei-Hsiu Liao, Pei-I Lin, Shing-Hwa Liu & Ruei-Ming Chen
Pages: 5941-5954
Published online: 22 Sep 2015
AbstractforChitosan nanofiber scaffold improves bone healing via stimulating trabecular bone production due to upregulation of the Runx2/osteocalcin/alkaline phosphatase signaling pathway | Full Text | References | PDF (7.3 MB)
  • 161 Views
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Article
Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
Gregory Marslin, Rajendran K Selvakesavan, Gregory Franklin, Bruno Sarmento & Alberto CP Dias
Pages: 5955-5963
Published online: 22 Sep 2015
AbstractforAntimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera | Full Text | References | PDF (2.7 MB)
  • 628 Views
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Article
Preparation, characterization, and safety evaluation of poly(lactide-co-glycolide) nanoparticles for protein delivery into macrophages
Anne-Sophie Guedj, Arnold J Kell, Michael Barnes, Sandra Stals, David Gonçalves, Denis Girard & Carole Lavigne
Pages: 5965-5979
Published online: 23 Sep 2015
AbstractforPreparation, characterization, and safety evaluation of poly(lactide-co-glycolide) nanoparticles for protein delivery into macrophages | Full Text | References | PDF (2.7 MB)
  • 63 Views
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Article
Sequential delivery of an anticancer drug and combined immunomodulatory nanoparticles for efficient chemoimmunotherapy
Min Beom Heo, Sun-Young Kim, Wan Soo Yun & Yong Taik Lim
Pages: 5981-5993
Published online: 24 Sep 2015
AbstractforSequential delivery of an anticancer drug and combined immunomodulatory nanoparticles for efficient chemoimmunotherapy | Full Text | References | PDF (3 MB)
  • 105 Views
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Article
Investigation of enzyme-sensitive lipid nanoparticles for delivery of siRNA to blood–brain barrier and glioma cells
Jonas Bruun, Trine B Larsen, Rasmus I Jølck, Rasmus Eliasen, René Holm, Torben Gjetting & Thomas L Andresen
Pages: 5995-6008
Published online: 24 Sep 2015
AbstractforInvestigation of enzyme-sensitive lipid nanoparticles for delivery of siRNA to blood–brain barrier and glioma cells | Full Text | References | PDF (2.6 MB)
  • 324 Views
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Article
Liposomal n-butylidenephthalide protects the drug from oxidation and enhances its antitumor effects in glioblastoma multiforme
Yu-Ling Lin, Kai-Fu Chang, Xiao-Fan Huang, Che-Lun Hung, Shyh-Chang Chen, Wan-Ru Chao, Kuang-Wen Liao & Nu-Man Tsai
Pages: 6009-6020
Published online: 28 Sep 2015
AbstractforLiposomal n-butylidenephthalide protects the drug from oxidation and enhances its antitumor effects in glioblastoma multiforme | Full Text | References | PDF (3.3 MB)
  • 46 Views
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Article
Nanoparticles of barium induce apoptosis in human phagocytes
Luana Mores, Eduardo Luzia França, Núbia Andrade Silva, Eliane Aparecida Suchara & Adenilda Cristina Honorio-França
Pages: 6021-6026
Published online: 28 Sep 2015
AbstractforNanoparticles of barium induce apoptosis in human phagocytes | Full Text | References | PDF (558.7 KB)
  • 64 Views
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Article
Positively charged micelles based on a triblock copolymer demonstrate enhanced corneal penetration
Jingguo Li, Zhanrong Li, Tianyang Zhou, Junjie Zhang, Huiyun Xia, Heng Li, Jijun He, Siyu He & Liya Wang
Pages: 6027-6037
Published online: 28 Sep 2015
AbstractforPositively charged micelles based on a triblock copolymer demonstrate enhanced corneal penetration | Full Text | References | PDF (1.4 MB)
  • 118 Views
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Review

Review Article
Nanomedicine applications in orthopedic medicine: state of the art
Mozhdeh Mazaheri, Niloofar Eslahi, Farideh Ordikhani, Elnaz Tamjid & Abdolreza Simchi
Pages: 6039-6054
Published online: 28 Sep 2015
AbstractforNanomedicine applications in orthopedic medicine: state of the art | Full Text | References | PDF (3.6 MB)
  • 207 Views
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Review Article
Natural product-based nanomedicine: recent advances and issues
Rebekah Watkins, Ling Wu, Chenming Zhang, Richey M Davis & Bin Xu
Pages: 6055-6074
Published online: 28 Sep 2015
AbstractforNatural product-based nanomedicine: recent advances and issues | Full Text | References | PDF (803.1 KB)
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Original Research

Article
Cytotoxicity of various types of gold-mesoporous silica nanoparticles in human breast cancer cells
Guomu Liu, Qiongshu Li, Weihua Ni, Nannan Zhang, Xiao Zheng, Yingshuai Wang, Dan Shao & Guixiang Tai
Pages: 6075-6087
Published online: 30 Sep 2015
AbstractforCytotoxicity of various types of gold-mesoporous silica nanoparticles in human breast cancer cells | Full Text | References | PDF (2.8 MB)
  • 121 Views
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Article
Effect of superparamagnetic iron oxide nanoparticles on fluidity and phase transition of phosphatidylcholine liposomal membranes
Poornima Budime Santhosh, Barbara Drašler, Damjana Drobne, Mateja Erdani Kreft, Slavko Kralj, Darko Makovec & Nataša Poklar Ulrih
Pages: 6089-6104
Published online: 29 Sep 2015
AbstractforEffect of superparamagnetic iron oxide nanoparticles on fluidity and phase transition of phosphatidylcholine liposomal membranes | Full Text | References | PDF (2.6 MB)
  • 93 Views
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Article
Silver nanoparticles induce tight junction disruption and astrocyte neurotoxicity in a rat blood–brain barrier primary triple coculture model
Liming Xu, Mo Dan, Anliang Shao, Xiang Cheng, Cuiping Zhang, Robert A Yokel, Taro Takemura, Nobutaka Hanagata, Masami Niwa & Daisuke Watanabe
Pages: 6105-6119
Published online: 29 Sep 2015
AbstractforSilver nanoparticles induce tight junction disruption and astrocyte neurotoxicity in a rat blood–brain barrier primary triple coculture model | Full Text | References | PDF (7.9 MB)
  • 132 Views
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Article
Nanoparticulated docetaxel exerts enhanced anticancer efficacy and overcomes existing limitations of traditional drugs
Jinhyang Choi, Eunjung Ko, Hye-Kyung Chung, Jae Hee Lee, Eun Jin Ju, Hyun Kyung Lim, Intae Park, Kab-Sig Kim, Joo-Hwan Lee, Woo-Chan Son, Jung Shin Lee, Joohee Jung, Seong-Yun Jeong, Si Yeol Song & Eun Kyung Choi
Pages: 6121-6132
Published online: 29 Sep 2015
AbstractforNanoparticulated docetaxel exerts enhanced anticancer efficacy and overcomes existing limitations of traditional drugs | Full Text | References | PDF (1.5 MB)
  • 70 Views
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Article
Environmental impact of multi-wall carbon nanotubes in a novel model of exposure: systemic distribution, macrophage accumulation, and amyloid deposition
Adriana Albini, Arianna Pagani, Laura Pulze, Antonino Bruno, Elisa Principi, Terenzio Congiu, Elisabetta Gini, Annalisa Grimaldi, Barbara Bassani, Silvio De Flora, Magda de Eguileor & Douglas M Noonan
Pages: 6133-6145
Published online: 29 Sep 2015
AbstractforEnvironmental impact of multi-wall carbon nanotubes in a novel model of exposure: systemic distribution, macrophage accumulation, and amyloid deposition | Full Text | References | PDF (7 MB)
  • 80 Views
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Article
Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe
Rehmana Rashid, Dong Wuk Kim, Abid Mehmood Yousaf, Omer Mustapha, Fakhar ud Din, Jong Hyuck Park, Chul Soon Yong, Yu-Kyoung Oh, Yu Seok Youn, Jong Oh Kim & Han-Gon Choi
Pages: 6147-6159
Published online: 30 Sep 2015
AbstractforComparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe | Full Text | References | PDF (1.6 MB)
  • 328 Views
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Article
Rapid and quantitative detection of C-reactive protein based on quantum dots and immunofiltration assay
Pengfei Zhang, Yan Bao, Mohamed Shehata Draz, Huiqi Lu, Chang Liu & Huanxing Han
Pages: 6161-6173
Published online: 30 Sep 2015
AbstractforRapid and quantitative detection of C-reactive protein based on quantum dots and immunofiltration assay | Full Text | References | PDF (2.8 MB)
  • 114 Views
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Article
Micellar emulsions composed of mPEG-PCL/MCT as novel nanocarriers for systemic delivery of genistein: a comparative study with micelles
Tianpeng Zhang, Huan Wang, Yanghuan Ye, Xingwang Zhang & Baojian Wu
Pages: 6175-6184
Published online: 01 Oct 2015
AbstractforMicellar emulsions composed of mPEG-PCL/MCT as novel nanocarriers for systemic delivery of genistein: a comparative study with micelles | Full Text | References | PDF (3.2 MB)
  • 69 Views
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Article
pH-Sensitive carboxymethyl chitosan-modified cationic liposomes for sorafenib and siRNA co-delivery
Yao Yao, Zhihui Su, Yanchao Liang & Na Zhang
Pages: 6185-6198
Published online: 01 Oct 2015
AbstractforpH-Sensitive carboxymethyl chitosan-modified cationic liposomes for sorafenib and siRNA co-delivery | Full Text | References | PDF (4.8 MB)
  • 155 Views
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Article
An efficient PEGylated liposomal nanocarrier containing cell-penetrating peptide and pH-sensitive hydrazone bond for enhancing tumor-targeted drug delivery
Yuan Ding, Dan Sun, Gui-Ling Wang, Hong-Ge Yang, Hai-Feng Xu, Jian-Hua Chen, Ying Xie & Zhi-Qiang Wang
Pages: 6199-6214
Published online: 01 Oct 2015
AbstractforAn efficient PEGylated liposomal nanocarrier containing cell-penetrating peptide and pH-sensitive hydrazone bond for enhancing tumor-targeted drug delivery | Full Text | References | PDF (4.7 MB)
  • 161 Views
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Article
Cerium oxide nanoparticle treatment ameliorates peritonitis-induced diaphragm dysfunction
Shinichi Asano, Ravikumar Arvapalli, Nandini DPK Manne, Mani Maheshwari, Bing Ma, Kevin M Rice, Vellaisamy Selvaraj & Eric R Blough
Pages: 6215-6226
Published online: 05 Oct 2015
AbstractforCerium oxide nanoparticle treatment ameliorates peritonitis-induced diaphragm dysfunction | Full Text | References | PDF (2.3 MB)
  • 55 Views
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Article
Anti-transferrin receptor-modified amphotericin B-loaded PLA–PEG nanoparticles cure Candidal meningitis and reduce drug toxicity
Xiaolong Tang, Yong Liang, Yongqiang Zhu, Chunmei Xie, Aixia Yao, Li Chen, Qinglin Jiang, Tingting Liu, Xiaoyu Wang, Yunyun Qian, Jia Wei, Wenxuan Ni, Jingjing Dai, Zhenyou Jiang & Wei Hou
Pages: 6227-6241
Published online: 05 Oct 2015
AbstractforAnti-transferrin receptor-modified amphotericin B-loaded PLA–PEG nanoparticles cure Candidal meningitis and reduce drug toxicity | Full Text | References | PDF (9 MB)
  • 94 Views
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Article
Effects of silver nanoparticles on neonatal testis development in mice
Xi-Feng Zhang, Sangiliyandi Gurunathan & Jin-Hoi Kim
Pages: 6243-6256
Published online: 05 Oct 2015
AbstractforEffects of silver nanoparticles on neonatal testis development in mice | Full Text | References | PDF (2.5 MB)
  • 146 Views
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Article
Reduced graphene oxide–silver nanoparticle nanocomposite: a potential anticancer nanotherapy
Sangiliyandi Gurunathan, Jae Woong Han, Jung Hyun Park, Eunsu Kim, Yun-Jung Choi, Deug-Nam Kwon & Jin-Hoi Kim
Pages: 6257-6276
Published online: 05 Oct 2015
AbstractforReduced graphene oxide–silver nanoparticle nanocomposite: a potential anticancer nanotherapy | Full Text | References | PDF (3.6 MB)
  • 509 Views
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Article
Physiologically based pharmacokinetic modeling of zinc oxide nanoparticles and zinc nitrate in mice
Wei-Yu Chen, Yi-Hsien Cheng, Nan-Hung Hsieh, Bo-Chun Wu, Wei-Chun Chou, Chia-Chi Ho, Jen-Kun Chen, Chung-Min Liao & Pinpin Lin
Pages: 6277-6292
Published online: 05 Oct 2015
AbstractforPhysiologically based pharmacokinetic modeling of zinc oxide nanoparticles and zinc nitrate in mice | Full Text | References | PDF (2.2 MB)
  • 126 Views
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Article
Sodium-22-radiolabeled silica nanoparticles as new radiotracer for biomedical applications: in vivo positron emission tomography imaging, biodistribution, and biocompatibility
Achraf Al Faraj, Basem Alotaibi, Abjal Pasha Shaik, Khaled Z Shamma, Ibrahim Al Jammaz & Jürgen Gerl
Pages: 6293-6302
Published online: 08 Oct 2015
AbstractforSodium-22-radiolabeled silica nanoparticles as new radiotracer for biomedical applications: in vivo positron emission tomography imaging, biodistribution, and biocompatibility | Full Text | References | PDF (1.1 MB)
  • 102 Views
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Article
In vivo biocompatibility of new nano-calcium-deficient hydroxyapatite/poly-amino acid complex biomaterials
Zhenyu Dai, Yue Li, Weizhong Lu, Dianming Jiang, Hong Li, Yonggang Yan, Guoyu Lv & Aiping Yang
Pages: 6303-6316
Published online: 06 Oct 2015
AbstractforIn vivo biocompatibility of new nano-calcium-deficient hydroxyapatite/poly-amino acid complex biomaterials | Full Text | References | PDF (10.6 MB)
  • 66 Views
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Article
Antimicrobial activity of bone cements embedded with organic nanoparticles
Stefano Perni, Victorien Thenault, Pauline Abdo, Katrin Margulis, Shlomo Magdassi & Polina Prokopovich
Pages: 6317-6329
Published online: 07 Oct 2015
AbstractforAntimicrobial activity of bone cements embedded with organic nanoparticles | Full Text | References | PDF (5 MB)
  • 150 Views
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Article
Combination of glycosphingosomes and liposomal doxorubicin shows increased activity against dimethyl-α-benzanthracene-induced fibrosarcoma in mice
Masood A Khan, Ahmed N Aljarbou, Yousef H Aldebasi, Mohammed S Alorainy & Arif Khan
Pages: 6331-6338
Published online: 27 Feb 2023
AbstractforCombination of glycosphingosomes and liposomal doxorubicin shows increased activity against dimethyl-α-benzanthracene-induced fibrosarcoma in mice | Full Text | References | PDF (1.2 MB)
  • 46 Views
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Article
Preparation, optimization, and in vitro simulated inhalation delivery of carvedilol nanoparticles loaded on a coarse carrier intended for pulmonary administration
Aly A Abdelbary, Abdulaziz M Al-mahallawi, Mohamed E Abdelrahim & Ahmed MA Ali
Pages: 6339-6353
Published online: 12 Oct 2015
AbstractforPreparation, optimization, and in vitro simulated inhalation delivery of carvedilol nanoparticles loaded on a coarse carrier intended for pulmonary administration | Full Text | References | PDF (3 MB)
  • 122 Views
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Article
Oral administration of encapsulated bovine lactoferrin protein nanocapsules against intracellular parasite Toxoplasma gondii
Namrata Anand, Rakesh Sehgal, Rupinder Kaur Kanwar, Mohan Lal Dubey, Rakesh Kumar Vasishta & Jagat Rakesh Kanwar
Pages: 6355-6369
Published online: 08 Oct 2015
AbstractforOral administration of encapsulated bovine lactoferrin protein nanocapsules against intracellular parasite Toxoplasma gondii | Full Text | References | PDF (4.1 MB)
  • 111 Views
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Review

Review Article
Nanotechnology in dentistry: prevention, diagnosis, and therapy
Ensanya Ali Abou Neel, Laurent Bozec, Roman A Perez, Hae-Won Kim & Jonathan C Knowles
Pages: 6371-6394
Published online: 08 Oct 2015
AbstractforNanotechnology in dentistry: prevention, diagnosis, and therapy | Full Text | References | PDF (4 MB)
  • 764 Views
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Original Research

Article
Preparation, characterization, in vivo pharmacokinetics, and biodistribution of polymeric micellar dimethoxycurcumin for tumor targeting
Hui Liu, Hui Xu, Yunxia Jiang, Shengyuan Hao, Feirong Gong, Hongjie Mu & Ke Liu
Pages: 6395-6410
Published online: 08 Oct 2015
AbstractforPreparation, characterization, in vivo pharmacokinetics, and biodistribution of polymeric micellar dimethoxycurcumin for tumor targeting | Full Text | References | PDF (3.2 MB)
  • 96 Views
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Article
Para amino benzoic acid-derived self-assembled biocompatible nanoparticles for efficient delivery of siRNA
Teegala Lakshminarayan Reddy, P Sivarama Krishnarao, Garikapati Koteswara Rao, Eswar Bhimireddy, P Venkateswarlu, Debendra K Mohapatra, JS Yadav, Utpal Bhadra & Manika Pal Bhadra
Pages: 6411-6424
Published online: 12 Oct 2015
AbstractforPara amino benzoic acid-derived self-assembled biocompatible nanoparticles for efficient delivery of siRNA | Full Text | References | PDF (6.7 MB)
  • 58 Views
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Article
Effect of particle size on oral absorption of carvedilol nanosuspensions: in vitro and in vivo evaluation
Dandan Liu, Hao Pan, Fengwei He, Xiaoyu Wang, Jinyu Li, Xinggang Yang & Weisan Pan
Pages: 6425-6434
Published online: 13 Oct 2015
AbstractforEffect of particle size on oral absorption of carvedilol nanosuspensions: in vitro and in vivo evaluation | Full Text | References | PDF (2.8 MB)
  • 139 Views
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Article
FePt nanoparticles as a potential X-ray activated chemotherapy agent for HeLa cells
Yanhong Zheng, Yunlan Tang, Zhirong Bao, Hui Wang, Feng Ren, Mingxiong Guo, Hong Quan & Changzhong Jiang
Pages: 6435-6444
Published online: 22 Oct 2015
AbstractforFePt nanoparticles as a potential X-ray activated chemotherapy agent for HeLa cells | Full Text | References | PDF (6.4 MB)
  • 55 Views
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Article
Hyaluronic acid-tagged silica nanoparticles in colon cancer therapy: therapeutic efficacy evaluation
Kai Liu, Zhi-qi Wang, Shi-jiang Wang, Ping Liu, Yue-hong Qin, Yan Ma, Xiao-Chen Li & Zhi-Jun Huo
Pages: 6445-6454
Published online: 27 Feb 2023
AbstractforHyaluronic acid-tagged silica nanoparticles in colon cancer therapy: therapeutic efficacy evaluation | Full Text | References | PDF (2.7 MB)
  • 148 Views
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Article
Attenuation of the macrophage inflammatory activity by TiO2 nanotubes via inhibition of MAPK and NF-κB pathways
Patricia Neacsu, Anca Mazare, Patrik Schmuki & Anisoara Cimpean
Pages: 6455-6467
Published online: 12 Oct 2015
AbstractforAttenuation of the macrophage inflammatory activity by TiO2 nanotubes via inhibition of MAPK and NF-κB pathways | Full Text | References | PDF (2.4 MB)
  • 80 Views
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Article
Enhancement of encapsulation efficiency of nanoemulsion-containing aripiprazole for the treatment of schizophrenia using mixture experimental design
Hamid Reza Fard Masoumi, Mahiran Basri, Wan Sarah Samiun, Zahra Izadiyan & Chaw Jiang Lim
Pages: 6469-6476
Published online: 13 Oct 2015
AbstractforEnhancement of encapsulation efficiency of nanoemulsion-containing aripiprazole for the treatment of schizophrenia using mixture experimental design | Full Text | References | PDF (1.2 MB)
  • 250 Views
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Article
Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity
Pallavi Krishna Shetty, Venkatesh Venuvanka, Hitesh Vitthal Jagani, Gejjalagere Honnappa Chethan, Virendra S Ligade, Prashant B Musmade, Usha Y Nayak, Meka Sreenivasa Reddy, Guruprasad Kalthur, Nayanabhirama Udupa, Chamallamudi Mallikarjuna Rao & Srinivas Mutalik
Pages: 6477-6491
Published online: 13 Oct 2015
AbstractforDevelopment and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity | Full Text | References | PDF (1.5 MB)
  • 680 Views
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Article
Design and evaluation of an intravesical delivery system for superficial bladder cancer: preparation of gemcitabine HCl-loaded chitosan–thioglycolic acid nanoparticles and comparison of chitosan/poloxamer gels as carriers
Zeynep Ay Şenyiğit, Sinem Yaprak Karavana, Derya İlem-Özdemir, Çağrı Çalışkan, Claudia Waldner, Sait Şen, Andreas Bernkop-Schnürch & Esra Baloğlu
Pages: 6493-6507
Published online: 27 Feb 2023
AbstractforDesign and evaluation of an intravesical delivery system for superficial bladder cancer: preparation of gemcitabine HCl-loaded chitosan–thioglycolic acid nanoparticles and comparison of chitosan/poloxamer gels as carriers | Full Text | References | PDF (3.5 MB)
  • 181 Views
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Article
A hyperspectral and toxicological analysis of protein corona impact on silver nanoparticle properties, intracellular modifications, and macrophage activation
Jonathan H Shannahan, Ramakrishna Podila & Jared M Brown
Pages: 6509-6521
Published online: 13 Oct 2015
AbstractforA hyperspectral and toxicological analysis of protein corona impact on silver nanoparticle properties, intracellular modifications, and macrophage activation | Full Text | References | PDF (1.9 MB)
  • 102 Views
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Article
Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool
Olga Scudiero, Ersilia Nigro, Marco Cantisani, Irene Colavita, Marilisa Leone, Flavia Anna Mercurio, Massimiliano Galdiero, Antonello Pessi, Aurora Daniele, Francesco Salvatore & Stefania Galdiero
Pages: 6523-6539
Published online: 15 Oct 2015
AbstractforDesign and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool | Full Text | References | PDF (5.7 MB)
  • 55 Views
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Article
Lipid nanoparticles for cyclosporine A administration: development, characterization, and in vitro evaluation of their immunosuppression activity
Melissa Guada, Victor Sebastián, Silvia Irusta, Esperanza Feijoó, María del Carmen Dios-Viéitez & María José Blanco-Prieto
Pages: 6541-6553
Published online: 16 Oct 2015
AbstractforLipid nanoparticles for cyclosporine A administration: development, characterization, and in vitro evaluation of their immunosuppression activity | Full Text | References | PDF (4.6 MB)
  • 131 Views
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Review

Review Article
Diagnosis of prostate cancer via nanotechnological approach
Benedict J Kang, Minhong Jeun, Gun Hyuk Jang, Sang Hoon Song, In Gab Jeong, Choung-Soo Kim, Peter C Searson & Kwan Hyi Lee
Pages: 6555-6569
Published online: 19 Oct 2015
AbstractforDiagnosis of prostate cancer via nanotechnological approach | Full Text | References | PDF (1.5 MB)
  • 92 Views
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Original Research

Article
A new method of wound treatment: targeted therapy of skin wounds with reactive oxygen species-responsive nanoparticles containing SDF-1α
Tao Tang, Hao Jiang, Yuan Yu, Fang He, Shi-zhao Ji, Ying-ying Liu, Zhong-shan Wang, Shi-chu Xiao, Cui Tang, Guang-Yi Wang & Zhao-Fan Xia
Pages: 6571-6585
Published online: 19 Oct 2015
AbstractforA new method of wound treatment: targeted therapy of skin wounds with reactive oxygen species-responsive nanoparticles containing SDF-1α | Full Text | References | PDF (10.4 MB)
  • 124 Views
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Article
Glutathione-degradable drug-loaded nanogel effectively and securely suppresses hepatoma in mouse model
Xingang Liu, Jianmeng Wang, Weiguo Xu, Jianxun Ding, Bo Shi, Kexin Huang, Xiuli Zhuang & Xuesi Chen
Pages: 6587-6602
Published online: 22 Oct 2015
AbstractforGlutathione-degradable drug-loaded nanogel effectively and securely suppresses hepatoma in mouse model | Full Text | References | PDF (5.4 MB)
  • 57 Views
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Article
Methotrexate-loaded lipid-core nanocapsules are highly effective in the control of inflammation in synovial cells and a chronic arthritis model
Antônio Luiz Boechat, Catiúscia Padilha de Oliveira, Andrea Monteiro Tarragô, Allyson Guimarães da Costa, Adriana Malheiro, Silvia Stanisçuaski Guterres & Adriana Raffin Pohlmann
Pages: 6603-6614
Published online: 22 Oct 2015
AbstractforMethotrexate-loaded lipid-core nanocapsules are highly effective in the control of inflammation in synovial cells and a chronic arthritis model | Full Text | References | PDF (1.2 MB)
  • 66 Views
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Article
Enhanced combination therapy effect on paclitaxel-resistant carcinoma by chloroquine co-delivery via liposomes
Menghua Gao, Yuzhen Xu & Liyan Qiu
Pages: 6615-6632
Published online: 22 Oct 2015
AbstractforEnhanced combination therapy effect on paclitaxel-resistant carcinoma by chloroquine co-delivery via liposomes | Full Text | References | PDF (6.9 MB)
  • 93 Views
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Article
Enhanced oral bioavailability of silymarin using liposomes containing a bile salt: preparation by supercritical fluid technology and evaluation in vitro and in vivo
Gang Yang, Yaping Zhao, Yongtai Zhang, Beilei Dang, Ying Liu & Nianping Feng
Pages: 6633-6644
Published online: 22 Oct 2015
AbstractforEnhanced oral bioavailability of silymarin using liposomes containing a bile salt: preparation by supercritical fluid technology and evaluation in vitro and in vivo | Full Text | References | PDF (1.8 MB)
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Article
The interaction of sterically stabilized magnetic nanoparticles with fresh human red blood cells
Binh TT Pham, Nirmesh Jain, Philip W Kuchel, Bogdan E Chapman, Stephanie A Bickley, Stephen K Jones & Brian S Hawkett
Pages: 6645-6655
Published online: 23 Oct 2015
AbstractforThe interaction of sterically stabilized magnetic nanoparticles with fresh human red blood cells | Full Text | References | PDF (1.8 MB)
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Corrigendum

Correction
Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles [Corrigendum]
Page: 6657
Published online: 28 Oct 2015
CitationforCytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles [Corrigendum] | Full Text | PDF (97.1 KB)
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Original Research

Article
Hierarchical micro/nanostructured titanium with balanced actions to bacterial and mammalian cells for dental implants
Yu Zhu, Huiliang Cao, Shichong Qiao, Manle Wang, Yingxin Gu, Huiwen Luo, Fanhao Meng, Xuanyong Liu & Hongchang Lai
Pages: 6659-6674
Published online: 27 Oct 2015
AbstractforHierarchical micro/nanostructured titanium with balanced actions to bacterial and mammalian cells for dental implants | Full Text | References | PDF (6.4 MB)
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Article
Microarc-oxidized titanium surfaces functionalized with microRNA-21-loaded chitosan/hyaluronic acid nanoparticles promote the osteogenic differentiation of human bone marrow mesenchymal stem cells
Zhongshan Wang, Guangsheng Wu, Zhihong Feng, Shizhu Bai, Yan Dong, Guofeng Wu & Yimin Zhao
Pages: 6675-6687
Published online: 27 Oct 2015
AbstractforMicroarc-oxidized titanium surfaces functionalized with microRNA-21-loaded chitosan/hyaluronic acid nanoparticles promote the osteogenic differentiation of human bone marrow mesenchymal stem cells | Full Text | References | PDF (5.5 MB)
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Article
Preclinical evaluation of a urokinase plasminogen activator receptor-targeted nanoprobe in rhesus monkeys
Yushu Chen, Li Gong, Ning Gao, Jichun Liao, Jiayu Sun, Yuqing Wang, Lei Wang, Pengjin Zhu, Qing Fan, Yongqiang Andrew Wang, Wen Zeng, Hui Mao, Lily Yang & Fabao Gao
Pages: 6689-6698
Published online: 28 Oct 2015
AbstractforPreclinical evaluation of a urokinase plasminogen activator receptor-targeted nanoprobe in rhesus monkeys | Full Text | References | PDF (3.2 MB)
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Article
Biodegradable mesoporous calcium–magnesium silicate-polybutylene succinate scaffolds for osseous tissue engineering
Xinxin Zhang, Chi Zhang, Wei Xu, Biao Zhong, Feng Lin, Jian Zhang, Quanxiang Wang, Jiajin Ji, Jie Wei & Yang Zhang
Pages: 6699-6708
Published online: 28 Oct 2015
AbstractforBiodegradable mesoporous calcium–magnesium silicate-polybutylene succinate scaffolds for osseous tissue engineering | Full Text | References | PDF (6 MB)
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Article
Fluorescent graphene quantum dots as traceable, pH-sensitive drug delivery systems
Jichuan Qiu, Ruibin Zhang, Jianhua Li, Yuanhua Sang, Wei Tang, Pilar Rivera Gil & Hong Liu
Pages: 6709-6724
Published online: 28 Oct 2015
AbstractforFluorescent graphene quantum dots as traceable, pH-sensitive drug delivery systems | Full Text | References | PDF (7.1 MB)
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Article
A novel nano-copper-bearing stainless steel with reduced Cu2+ release only inducing transient foreign body reaction via affecting the activity of NF-κB and Caspase 3
Lei Wang, Ling Ren, Tingting Tang, Kerong Dai, Ke Yang & Yongqiang Hao
Pages: 6725-6739
Published online: 29 Oct 2015
AbstractforA novel nano-copper-bearing stainless steel with reduced Cu2+ release only inducing transient foreign body reaction via affecting the activity of NF-κB and Caspase 3 | Full Text | References | PDF (6.3 MB)
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Article
Anti-hyperglycemic activity of selenium nanoparticles in streptozotocin-induced diabetic rats
Saleh Al-Quraishy, Mohamed A Dkhil & Ahmed Esmat Abdel Moneim
Pages: 6741-6756
Published online: 29 Oct 2015
AbstractforAnti-hyperglycemic activity of selenium nanoparticles in streptozotocin-induced diabetic rats | Full Text | References | PDF (6.4 MB)
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Review

Review Article
Recent trends in the development of nanophytobioactive compounds and delivery systems for their possible role in reducing oxidative stress in Parkinson’s disease models
Palanivel Ganesan, Hyun-Myung Ko, In-Su Kim & Dong-Kug Choi
Pages: 6757-6772
Published online: 27 Feb 2023
AbstractforRecent trends in the development of nanophytobioactive compounds and delivery systems for their possible role in reducing oxidative stress in Parkinson’s disease models | Full Text | References | PDF (1 MB)
  • 244 Views
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Original Research

Article
Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy
Narsireddy Amreddy, Ranganayaki Muralidharan, Anish Babu, Meghna Mehta, Elyse V Johnson, Yan D Zhao, Anupama Munshi & Rajagopal Ramesh
Pages: 6773-6788
Published online: 29 Oct 2015
AbstractforTumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy | Full Text | References | PDF (2.4 MB)
  • 136 Views
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Article
RETRACTED ARTICLE: PLGA-encapsulated tea polyphenols enhance the chemotherapeutic efficacy of cisplatin against human cancer cells and mice bearing Ehrlich ascites carcinoma
Madhulika Singh, Priyanka Bhatnagar, Sanjay Mishra, Pradeep Kumar, Yogeshwer Shukla & Kailash Chand Gupta
Pages: 6789-6809
Published online: 27 Feb 2023
AbstractforRETRACTED ARTICLE: PLGA-encapsulated tea polyphenols enhance the chemotherapeutic efficacy of cisplatin against human cancer cells and mice bearing Ehrlich ascites carcinoma | PDF (4.7 MB)
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Article
Detection of fluorescent organic nanoparticles by confocal laser endomicroscopy in a rat model of Barrett’s esophageal adenocarcinoma
Elisa Dassie, Diletta Arcidiacono, Iga Wasiak, Nunzio Damiano, Luigi Dall’Olmo, Cinzia Giacometti, Sonia Facchin, Mauro Cassaro, Ennio Guido, Franca De Lazzari, Oriano Marin, Tomasz Ciach, Suzanne Fery-Forgues, Alfredo Alberti, Giorgio Battaglia & Stefano Realdon
Pages: 6811-6823
Published online: 30 Oct 2015
AbstractforDetection of fluorescent organic nanoparticles by confocal laser endomicroscopy in a rat model of Barrett’s esophageal adenocarcinoma | Full Text | References | PDF (2.3 MB)
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Article
An in vitro and in vivo study of gemcitabine-loaded albumin nanoparticles in a pancreatic cancer cell line
Xinzhe Yu, Yang Di, Chao Xie, Yunlong Song, Hang He, Hengchao Li, Xinming Pu, Weiyue Lu, Deliang Fu & Chen Jin
Pages: 6825-6834
Published online: 30 Oct 2015
AbstractforAn in vitro and in vivo study of gemcitabine-loaded albumin nanoparticles in a pancreatic cancer cell line | Full Text | References | PDF (2.5 MB)
  • 224 Views
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Article
Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment
Vanna Sanna, Jean Christopher Chamcheu, Nicolino Pala, Hasan Mukhtar, Mario Sechi & Imtiaz Ahmad Siddiqui
Pages: 6835-6846
Published online: 30 Oct 2015
AbstractforNanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment | Full Text | References | PDF (3.2 MB)
  • 113 Views
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Article
Graphene oxide-silver nanocomposite as a promising biocidal agent against methicillin-resistant Staphylococcus aureus
Ana Carolina Mazarin de Moraes, Bruna Araujo Lima, Andreia Fonseca de Faria, Marcelo Brocchi & Oswaldo Luiz Alves
Pages: 6847-6861
Published online: 02 Nov 2015
AbstractforGraphene oxide-silver nanocomposite as a promising biocidal agent against methicillin-resistant Staphylococcus aureus | Full Text | References | PDF (7.2 MB)
  • 212 Views
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Letter

Letter
Review on lipegfilgrastim
Maja Gasparic & Sophie Leyman
Pages: 6863-6864
Published online: 03 Nov 2015
CitationforReview on lipegfilgrastim | Full Text | References | PDF (160.7 KB)
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Original Research

Article
Photosensitizer and peptide-conjugated PAMAM dendrimer for targeted in vivo photodynamic therapy
Amreddy Narsireddy, Kurra Vijayashree, Mahesh G Adimoolam, Sunkara V Manorama & Nalam M Rao
Pages: 6865-6878
Published online: 27 Feb 2023
AbstractforPhotosensitizer and peptide-conjugated PAMAM dendrimer for targeted in vivo photodynamic therapy | Full Text | References | PDF (3 MB)
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Article
Enhanced bioavailability of nerve growth factor with phytantriol lipid-based crystalline nanoparticles in cochlea
Meng Bu, Jingling Tang, Yinghui Wei, Yanhui Sun, Xinyu Wang, Linhua Wu & Hongzhuo Liu
Pages: 6879-6889
Published online: 27 Feb 2023
AbstractforEnhanced bioavailability of nerve growth factor with phytantriol lipid-based crystalline nanoparticles in cochlea | Full Text | References | PDF (3.4 MB)
  • 62 Views
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Article
Visible-light-responsive ZnCuO nanoparticles: benign photodynamic killers of infectious protozoans
Akhtar Nadhman, Samina Nazir, Malik Ihsanullah Khan, Attiya Ayub, Bakhtiar Muhammad, Momin Khan, Dilawar Farhan Shams & Masoom Yasinzai
Pages: 6891-6903
Published online: 27 Feb 2023
AbstractforVisible-light-responsive ZnCuO nanoparticles: benign photodynamic killers of infectious protozoans | Full Text | References | PDF (1.1 MB)
  • 98 Views
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Article
Aqueous extract of Rabdosia rubescens leaves: forming nanoparticles, targeting P-selectin, and inhibiting thrombosis
Yuji Wang, Jingcheng Tang, Haimei Zhu, Xueyun Jiang, Jiawang Liu, Wenyun Xu, Haiping Ma, Qiqi Feng, Jianhui Wu, Ming Zhao & Shiqi Peng
Pages: 6905-6918
Published online: 27 Feb 2023
AbstractforAqueous extract of Rabdosia rubescens leaves: forming nanoparticles, targeting P-selectin, and inhibiting thrombosis | Full Text | References | PDF (3.3 MB)
  • 98 Views
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Article
Ganglioside-magnetosome complex formation enhances uptake of gangliosides by cells
Feng Guan, Xiang Li, Jia Guo, Ganglong Yang & Xiang Li
Pages: 6919-6930
Published online: 27 Feb 2023
AbstractforGanglioside-magnetosome complex formation enhances uptake of gangliosides by cells | Full Text | References | PDF (3.4 MB)
  • 48 Views
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Article
Nanoshell-mediated photothermal therapy can enhance chemotherapy in inflammatory breast cancer cells
Brittany L Fay, Jilian R Melamed & Emily S Day
Pages: 6931-6941
Published online: 06 Nov 2015
AbstractforNanoshell-mediated photothermal therapy can enhance chemotherapy in inflammatory breast cancer cells | Full Text | References | PDF (4 MB)
  • 408 Views
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Article
Engineering iodine-doped carbon dots as dual-modal probes for fluorescence and X-ray CT imaging
Miaomiao Zhang, Huixiang Ju, Li Zhang, Mingzhong Sun, Zhongwei Zhou, Zhenyu Dai, Lirong Zhang, Aihua Gong, Chaoyao Wu & Fengyi Du
Pages: 6943-6953
Published online: 27 Feb 2023
AbstractforEngineering iodine-doped carbon dots as dual-modal probes for fluorescence and X-ray CT imaging | Full Text | References | PDF (3.5 MB)
  • 187 Views
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Article
The effects of hierarchical micro/nanosurfaces decorated with TiO2 nanotubes on the bioactivity of titanium implants in vitro and in vivo
Xianglong Ding, Lei Zhou, Jingxu Wang, Qingxia Zhao, Xi Lin, Yan Gao, Shaobing Li, Jingyi Wu, Mingdeng Rong, Zehong Guo, Chunhua Lai, Haibin Lu & Fang Jia
Pages: 6955-6973
Published online: 27 Feb 2023
AbstractforThe effects of hierarchical micro/nanosurfaces decorated with TiO2 nanotubes on the bioactivity of titanium implants in vitro and in vivo | Full Text | References | PDF (14.3 MB)
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Perspectives

Article
Amyloids in solid-state nuclear magnetic resonance: potential causes of the usually low resolution
Alba Espargaró, Maria Antònia Busquets, Joan Estelrich & Raimon Sabate
Pages: 6975-6983
Published online: 27 Feb 2023
AbstractforAmyloids in solid-state nuclear magnetic resonance: potential causes of the usually low resolution | Full Text | References | PDF (2.6 MB)
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Original Research

Article
Hypericin-bearing magnetic iron oxide nanoparticles for selective drug delivery in photodynamic therapy
Harald Unterweger, Daniel Subatzus, Rainer Tietze, Christina Janko, Marina Poettler, Alfons Stiegelschmitt, Matthias Schuster, Caroline Maake, Aldo R Boccaccini & Christoph Alexiou
Pages: 6985-6996
Published online: 12 Nov 2015
AbstractforHypericin-bearing magnetic iron oxide nanoparticles for selective drug delivery in photodynamic therapy | Full Text | References | PDF (3.8 MB)
  • 73 Views
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Article
Specific detection of CD133-positive tumor cells with iron oxide nanoparticles labeling using noninvasive molecular magnetic resonance imaging
Ya-Wen Chen, Gunn-Guang Liou, Huay-Ben Pan, Hui-Hwa Tseng, Yu-Ting Hung & Chen-Pin Chou
Pages: 6997-7018
Published online: 11 Nov 2015
AbstractforSpecific detection of CD133-positive tumor cells with iron oxide nanoparticles labeling using noninvasive molecular magnetic resonance imaging | Full Text | References | PDF (8.9 MB)
  • 57 Views
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Article
Phytofabrication of bioinduced silver nanoparticles for biomedical applications
Nabeel Ahmad, Sharad Bhatnagar, Syed Salman Ali & Rajiv Dutta
Pages: 7019-7030
Published online: 12 Nov 2015
AbstractforPhytofabrication of bioinduced silver nanoparticles for biomedical applications | Full Text | References | PDF (3.2 MB)
  • 201 Views
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Article
Effect of micro-nano-hybrid structured hydroxyapatite bioceramics on osteogenic and cementogenic differentiation of human periodontal ligament stem cell via Wnt signaling pathway
Lixia Mao, Jiaqiang Liu, Jinglei Zhao, Jiang Chang, Lunguo Xia, Lingyong Jiang, Xiuhui Wang, Kaili Lin & Bing Fang
Pages: 7031-7044
Published online: 12 Nov 2015
AbstractforEffect of micro-nano-hybrid structured hydroxyapatite bioceramics on osteogenic and cementogenic differentiation of human periodontal ligament stem cell via Wnt signaling pathway | Full Text | References | PDF (5.7 MB)
  • 87 Views
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Article
Intracellular targeted co-delivery of shMDR1 and gefitinib with chitosan nanoparticles for overcoming multidrug resistance
Xiwei Yu, Guang Yang, Yijie Shi, Chang Su, Ming Liu, Bo Feng & Liang Zhao
Pages: 7045-7056
Published online: 12 Nov 2015
AbstractforIntracellular targeted co-delivery of shMDR1 and gefitinib with chitosan nanoparticles for overcoming multidrug resistance | Full Text | References | PDF (4.1 MB)
  • 78 Views
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Article
Silver nanoparticles cause complications in pregnant mice
Xi-Feng Zhang, Jung-Hyun Park, Yun-Jung Choi, Min-Hee Kang, Sangiliyandi Gurunathan & Jin-Hoi Kim
Pages: 7057-7071
Published online: 13 Nov 2015
AbstractforSilver nanoparticles cause complications in pregnant mice | Full Text | References | PDF (2.5 MB)
  • 113 Views
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Article
Role of surface charge in determining the biological effects of CdSe/ZnS quantum dots
Qiangqiang Liu, Hongxia Li, Qiyue Xia, Ying Liu & Kai Xiao
Pages: 7073-7088
Published online: 16 Nov 2015
AbstractforRole of surface charge in determining the biological effects of CdSe/ZnS quantum dots | Full Text | References | PDF (6.7 MB)
  • 94 Views
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Article
Assessing the axonal translocation of CeO2 and SiO2 nanoparticles in the sciatic nerve fibers of the frog: an ex vivo electrophysiological study
Georgia Kastrinaki, Christos Samsouris, Efstratios K Kosmidis, Eleni Papaioannou, Athanasios G Konstandopoulos & George Theophilidis
Pages: 7089-7096
Published online: 19 Nov 2015
AbstractforAssessing the axonal translocation of CeO2 and SiO2 nanoparticles in the sciatic nerve fibers of the frog: an ex vivo electrophysiological study | Full Text | References | PDF (1.1 MB)
  • 53 Views
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Article
Efficient gene delivery to human umbilical cord mesenchymal stem cells by cationized Porphyra yezoensis polysaccharide nanoparticles
Qingtong Yu, Jin Cao, Baoding Chen, Wenwen Deng, Xia Cao, Jingjing Chen, Yan Wang, Shicheng Wang, Jiangnan Yu, Ximing Xu & Xiangdong Gao
Pages: 7097-7107
Published online: 18 Nov 2015
AbstractforEfficient gene delivery to human umbilical cord mesenchymal stem cells by cationized Porphyra yezoensis polysaccharide nanoparticles | Full Text | References | PDF (1.9 MB)
  • 57 Views
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Article
Osteoinductive peptide-functionalized nanofibers with highly ordered structure as biomimetic scaffolds for bone tissue engineering
Xiang Gao, Xiaohong Zhang, Jinlin Song, Xiao Xu, Anxiu Xu, Mengke Wang, Bingwu Xie, Enyi Huang, Feng Deng & Shicheng Wei
Pages: 7109-7128
Published online: 18 Nov 2015
AbstractforOsteoinductive peptide-functionalized nanofibers with highly ordered structure as biomimetic scaffolds for bone tissue engineering | Full Text | References | PDF (8.6 MB)
  • 91 Views
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Article
Combination of PEI-Mn0.5Zn0.5Fe2O4 nanoparticles and pHsp 70-HSV-TK/GCV with magnet-induced heating for treatment of hepatoma
Qiusha Tang, Mudan Lu, Daozhen Chen & Peidang Liu
Pages: 7129-7143
Published online: 18 Nov 2015
AbstractforCombination of PEI-Mn0.5Zn0.5Fe2O4 nanoparticles and pHsp 70-HSV-TK/GCV with magnet-induced heating for treatment of hepatoma | Full Text | References | PDF (4.9 MB)
  • 41 Views
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Article
The diameter of nanotubes formed on Ti-6Al-4V alloy controls the adhesion and differentiation of Saos-2 cells
Elena Filova, Jaroslav Fojt, Marketa Kryslova, Hynek Moravec, Ludek Joska & Lucie Bacakova
Pages: 7145-7163
Published online: 20 Nov 2015
AbstractforThe diameter of nanotubes formed on Ti-6Al-4V alloy controls the adhesion and differentiation of Saos-2 cells | Full Text | References | PDF (8.2 MB)
  • 80 Views
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Article
Treatment of a multiple sclerosis animal model by a novel nanodrop formulation of a natural antioxidant
Orli Binyamin, Liraz Larush, Kati Frid, Guy Keller, Yael Friedman-Levi, Haim Ovadia, Oded Abramsky, Shlomo Magdassi & Ruth Gabizon
Pages: 7165-7174
Published online: 20 Nov 2015
AbstractforTreatment of a multiple sclerosis animal model by a novel nanodrop formulation of a natural antioxidant | Full Text | References | PDF (2.9 MB)
  • 106 Views
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Article
A nanomedicine-promising approach to provide an appropriate colon-targeted drug delivery system for 5-fluorouracil
Sima Singh, Niranjan G Kotla, Sonia Tomar, Balaji Maddiboyina, Thomas J Webster, Dinesh Sharma & Omprakash Sunnapu
Pages: 7175-7182
Published online: 23 Nov 2015
AbstractforA nanomedicine-promising approach to provide an appropriate colon-targeted drug delivery system for 5-fluorouracil | Full Text | References | PDF (2.5 MB)
  • 184 Views
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Article
Development of polymeric–cationic peptide composite nanoparticles, a nanoparticle-in-nanoparticle system for controlled gene delivery
Arvind K Jain, Ashley Massey, Helmy Yusuf, Denise M McDonald, Helen O McCarthy & Vicky L Kett
Pages: 7183-7196
Published online: 24 Nov 2015
AbstractforDevelopment of polymeric–cationic peptide composite nanoparticles, a nanoparticle-in-nanoparticle system for controlled gene delivery | Full Text | References | PDF (3.2 MB)
  • 78 Views
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Article
Enhanced detection of single-cell-secreted proteins using a fluorescent immunoassay on the protein-G-terminated glass substrate
Yoon Jeong, Kwan Hong Lee, Hansoo Park & Jonghoon Choi
Pages: 7197-7205
Published online: 27 Feb 2023
AbstractforEnhanced detection of single-cell-secreted proteins using a fluorescent immunoassay on the protein-G-terminated glass substrate | Full Text | References | PDF (2.5 MB)
  • 61 Views
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Article
Green synthesis of silver nanoparticles using cranberry powder aqueous extract: characterization and antimicrobial properties
Asmaa A Ashour, Dina Raafat, Hanan M El-Gowelli & Amal H El-Kamel
Pages: 7207-7221
Published online: 01 Dec 2015
AbstractforGreen synthesis of silver nanoparticles using cranberry powder aqueous extract: characterization and antimicrobial properties | Full Text | References | PDF (5.1 MB)
  • 337 Views
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Article
Distribution of β-carotene-encapsulated polysorbate 80-coated poly(D, L-lactide-co-glycolide) nanoparticles in rodent tissues following intravenous administration
Taiki Miyazawa, Kiyotaka Nakagawa, Takahiro Harigae, Ryo Onuma, Fumiko Kimura, Tomoyuki Fujii & Teruo Miyazawa
Pages: 7223-7230
Published online: 27 Feb 2023
AbstractforDistribution of β-carotene-encapsulated polysorbate 80-coated poly(D, L-lactide-co-glycolide) nanoparticles in rodent tissues following intravenous administration | Full Text | References | PDF (1.1 MB)
  • 65 Views
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Article
Combination of calcium sulfate and simvastatin-controlled release microspheres enhances bone repair in critical-sized rat calvarial bone defects
Yin-Chih Fu, Yan-Hsiung Wang, Chung-Hwan Chen, Chih-Kuang Wang, Gwo-Jaw Wang & Mei-Ling Ho
Pages: 7231-7240
Published online: 01 Dec 2015
AbstractforCombination of calcium sulfate and simvastatin-controlled release microspheres enhances bone repair in critical-sized rat calvarial bone defects | Full Text | References | PDF (5.8 MB)
  • 58 Views
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Article
Antimicrobial activity and cytocompatibility of silver nanoparticles coated catheters via a biomimetic surface functionalization strategy
Ke Wu, Yun Yang, Yanmei Zhang, Jiexi Deng & Changjian Lin
Pages: 7241-7252
Published online: 02 Dec 2015
AbstractforAntimicrobial activity and cytocompatibility of silver nanoparticles coated catheters via a biomimetic surface functionalization strategy | Full Text | References | PDF (7.7 MB)
  • 155 Views
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Article
Novel green synthesis of gold nanoparticles using Citrullus lanatus rind and investigation of proteasome inhibitory activity, antibacterial, and antioxidant potential
Jayanta Kumar Patra & Kwang-Hyun Baek
Pages: 7253-7264
Published online: 02 Dec 2015
AbstractforNovel green synthesis of gold nanoparticles using Citrullus lanatus rind and investigation of proteasome inhibitory activity, antibacterial, and antioxidant potential | Full Text | References | PDF (2.1 MB)
  • 442 Views
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Article
Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles
Ying-Chen Chen, Chia-Yu Su, Hua-Jun Jhan, Hsiu-O Ho & Ming-Thau Sheu
Pages: 7265-7274
Published online: 02 Dec 2015
AbstractforPhysical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles | Full Text | References | PDF (1.6 MB)
  • 120 Views
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Article
Induction of systemic and mucosal immunity against methicillin-resistant Staphylococcus aureus infection by a novel nanoemulsion adjuvant vaccine
HongWu Sun, Chao Wei, BaoShuai Liu, HaiMing Jing, Qiang Feng, YaNan Tong, Yun Yang, LiuYang Yang, QianFei Zuo, Yi Zhang, QuanMing Zou & Hao Zeng
Pages: 7275-7290
Published online: 03 Dec 2015
AbstractforInduction of systemic and mucosal immunity against methicillin-resistant Staphylococcus aureus infection by a novel nanoemulsion adjuvant vaccine | Full Text | References | PDF (4.5 MB)
  • 73 Views
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Article
Enhanced antitumor effects by docetaxel/LL37-loaded thermosensitive hydrogel nanoparticles in peritoneal carcinomatosis of colorectal cancer
Rangrang Fan, Aiping Tong, Xiaoling Li, Xiang Gao, Lan Mei, Liangxue Zhou, Xiaoning Zhang, Chao You & Gang Guo
Pages: 7291-7305
Published online: 27 Feb 2023
AbstractforEnhanced antitumor effects by docetaxel/LL37-loaded thermosensitive hydrogel nanoparticles in peritoneal carcinomatosis of colorectal cancer | Full Text | References | PDF (4.5 MB)
  • 162 Views
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Article
Highly efficient mesenchymal stem cell proliferation on poly-ε-caprolactone nanofibers with embedded magnetic nanoparticles
Jana Daňková, Matej Buzgo, Jana Vejpravová, Simona Kubíčková, Věra Sovková, Lucie Vysloužilová, Alice Mantlíková, Alois Nečas & Evžen Amler
Pages: 7307-7317
Published online: 07 Dec 2015
AbstractforHighly efficient mesenchymal stem cell proliferation on poly-ε-caprolactone nanofibers with embedded magnetic nanoparticles | Full Text | References | PDF (3.6 MB)
  • 83 Views
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Perspectives

Article
Nanomedicine concepts in the general medical curriculum: initiating a discussion
Aldrin E Sweeney
Pages: 7319-7331
Published online: 07 Dec 2015
AbstractforNanomedicine concepts in the general medical curriculum: initiating a discussion | Full Text | References | PDF (344.7 KB)
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Original Research

Article
Hydroxyapatite-doped polycaprolactone nanofiber membrane improves tendon–bone interface healing for anterior cruciate ligament reconstruction
Fei Han, Peng Zhang, Yaying Sun, Chao Lin, Peng Zhao & Jiwu Chen
Pages: 7333-7343
Published online: 07 Dec 2015
AbstractforHydroxyapatite-doped polycaprolactone nanofiber membrane improves tendon–bone interface healing for anterior cruciate ligament reconstruction | Full Text | References | PDF (5.7 MB)
  • 129 Views
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Article
Inhibition of heat-shock protein 90 sensitizes liver cancer stem-like cells to magnetic hyperthermia and enhances anti-tumor effect on hepatocellular carcinoma-burdened nude mice
Rui Yang, Qiusha Tang, Fengqin Miao, Yanli An, Mengfei Li, Yong Han, Xihui Wang, Juan Wang, Peidang Liu & Rong Chen
Pages: 7345-7358
Published online: 27 Feb 2023
AbstractforInhibition of heat-shock protein 90 sensitizes liver cancer stem-like cells to magnetic hyperthermia and enhances anti-tumor effect on hepatocellular carcinoma-burdened nude mice | Full Text | References | PDF (4.5 MB)
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pH-responsive glycol chitosan-cross-linked carboxymethyl-β-cyclodextrin nanoparticles for controlled release of anticancer drugs
Yiwen Wang, Fei Qin, Haina Tan, Yan Zhang, Miao Jiang, Mei Lu & Xin Yao
Pages: 7359-7370
Published online: 08 Dec 2015
AbstractforpH-responsive glycol chitosan-cross-linked carboxymethyl-β-cyclodextrin nanoparticles for controlled release of anticancer drugs | Full Text | References | PDF (2.7 MB)
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Investigation and optimization of formulation parameters on preparation of targeted anti-CD205 tailored PLGA nanoparticles
Sheikh Tasnim Jahan & Azita Haddadi
Pages: 7371-7384
Published online: 10 Dec 2015
AbstractforInvestigation and optimization of formulation parameters on preparation of targeted anti-CD205 tailored PLGA nanoparticles | Full Text | References | PDF (2.6 MB)
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Enhanced human bone marrow mesenchymal stem cell functions on cathodic arc plasma-treated titanium
Wei Zhu, George Teel, Christopher M O’Brien, Taisen Zhuang, Michael Keidar & Lijie Grace Zhang
Pages: 7385-7396
Published online: 10 Dec 2015
AbstractforEnhanced human bone marrow mesenchymal stem cell functions on cathodic arc plasma-treated titanium | Full Text | References | PDF (3.9 MB)
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A toxic organic solvent-free technology for the preparation of PEGylated paclitaxel nanosuspension based on human serum albumin for effective cancer therapy
Tingjie Yin, Lihui Dong, Bei Cui, Lei Wang, Lifang Yin, Jianping Zhou & Meirong Huo
Pages: 7397-7412
Published online: 11 Dec 2015
AbstractforA toxic organic solvent-free technology for the preparation of PEGylated paclitaxel nanosuspension based on human serum albumin for effective cancer therapy | Full Text | References | PDF (3.1 MB)
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Mechanistic study of decreased skin penetration using a combination of sonophoresis with sodium fluorescein-loaded PEGylated liposomes with d-limonene
Worranan Rangsimawong, Praneet Opanasopit, Theerasak Rojanarata & Tanasait Ngawhirunpat
Pages: 7413-7423
Published online: 15 Dec 2015
AbstractforMechanistic study of decreased skin penetration using a combination of sonophoresis with sodium fluorescein-loaded PEGylated liposomes with d-limonene | Full Text | References | PDF (4.4 MB)
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In vitro controlled release of cisplatin from gold-carbon nanobottles via cleavable linkages
Jian Li, Sia Lee Yoong, Wei Jiang Goh, Bertrand Czarny, Zhi Yang, Kingshuk Poddar, Michal M Dykas, Abhijeet Patra, T Venkatesan, Tomasz Panczyk, Chengkuo Lee & Giorgia Pastorin
Pages: 7425-7441
Published online: 27 Feb 2023
AbstractforIn vitro controlled release of cisplatin from gold-carbon nanobottles via cleavable linkages | Full Text | References | PDF (6.7 MB)
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Therapeutic and scintigraphic applications of polymeric micelles: combination of chemotherapy and radiotherapy in hepatocellular carcinoma
Ying-Hsia Shih, Cheng-Liang Peng, Ping-Fang Chiang, Wuu-Jyh Lin, Tsai-Yueh Luo & Ming-Jium Shieh
Pages: 7443-7454
Published online: 16 Dec 2015
AbstractforTherapeutic and scintigraphic applications of polymeric micelles: combination of chemotherapy and radiotherapy in hepatocellular carcinoma | Full Text | References | PDF (4.6 MB)
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Liquid crystal precursor mucoadhesive system as a strategy to improve the prophylactic action of Syngonanthus nitens (Bong.) Ruhland against infection by Candida krusei
Matheus Aparecido dos Santos Ramos, Giovana Calixto, Luciani Gaspar de Toledo, Bruna Vidal Bonifácio, Lourdes Campaner dos Santos, Margarete Teresa Gottardo de Almeida, Marlus Chorilli & Taís Maria Bauab
Pages: 7455-7466
Published online: 27 Feb 2023
AbstractforLiquid crystal precursor mucoadhesive system as a strategy to improve the prophylactic action of Syngonanthus nitens (Bong.) Ruhland against infection by Candida krusei | Full Text | References | PDF (1.2 MB)
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Antioxidant and hepatoprotective role of gold nanoparticles against murine hepatic schistosomiasis
Mohamed A Dkhil, Amira A Bauomy, Marwa SM Diab & Saleh Al-Quraishy
Pages: 7467-7475
Published online: 16 Dec 2015
AbstractforAntioxidant and hepatoprotective role of gold nanoparticles against murine hepatic schistosomiasis | Full Text | References | PDF (1.7 MB)
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Novel platinum–palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: anticancer and antioxidant activities
Sougata Ghosh, Rahul Nitnavare, Ankush Dewle, Geetanjali B Tomar, Rohan Chippalkatti, Piyush More, Rohini Kitture, Sangeeta Kale, Jayesh Bellare & Balu A Chopade
Pages: 7477-7490
Published online: 17 Dec 2015
AbstractforNovel platinum–palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: anticancer and antioxidant activities | Full Text | References | PDF (3.3 MB)
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