Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 2
524
Views
2
CrossRef citations to date
0
Altmetric
General Xenobiochemistry

Interspecies scaling of urinary excretory amounts of nine drugs belonging to different therapeutic areas with diverse chemical structures – accurate prediction of the human urinary excretory amounts

, &
Pages 112-118 | Received 04 Feb 2016, Accepted 11 Mar 2016, Published online: 19 Apr 2016

References

  • Bansal AD, Hill CE, Berns JS. (2015). Use of Antiepileptic drugs in patients with chronic kidney disease and end stage renal disease. Semin Dial 28:404–12
  • Benjamin B, Sahu M, Bhatnagar U, et al. (2012). The observed correlation between in vivo clinical pharmacokinetic parameters and in vitro potency of VEGFR-2 inhibitors. Can this be used as a prospective guide for the development of novel compounds? Arzneimittelforschung 62:194–201
  • Benziger DP, Balfour K, Clemans S, Edelson J. (1977). Absorption, excretion and disposition of cyclindole in laboratory animals and human volunteers. Drug Metab Dispos 5:239–45
  • Cabana BE, van Harken DR, Hottendorf GH. (1976). Comparative pharmacokinetics and metabolism of cephapirin in laboratory animals and humans. Antimicrob Agents Chemother 10:307–17
  • Hall C, Mošat A, Lueshen E, Linninger A. (2012). Interspecies scaling in pharmacokinetics: a novel whole-body physiologically based modeling framework to discover drug biodistribution mechanisms in vivo. J Pharm Sci 101:1221–41
  • Hopkins R, Martin LE, Bland R. (1976). The metabolism of labetalol in animals and man. Biochem Soc Trans 4:726–9
  • Klotz U. (2009). Pharmacokinetics and drug metabolism in the elderly. Drug Metab Rev 41:67–76
  • Mamidi RN, Mannens G, Annaert P, et al. (2007). Metabolism and excretion of RWJ-333369 [1,2-ethanediol, 1-(2-chlorophenyl)-, 2-carbamate, (S)-] in mice, rats, rabbits, and dogs. Drug Metab Dispos 35:566–77
  • Mannens GS, Hendrickx J, Janssen CG, et al. (2007). The absorption, metabolism, and excretion of the novel neuromodulator RWJ-333369 (1,2-ethanediol, [1-2-chlorophenyl]-, 2-carbamate, [S]-) in humans. Drug Metab Dispos 35:554–65
  • Mattiuz E, Franklin R, Gillespie T, et al. (1997). Disposition and metabolism of olanzapine in mice, dogs, and rhesus monkeys. Drug Metab Dispos 25:573–83
  • Ramji JV, Keogh JP, Blake TJ, et al. (1999). Disposition of ropinirole in animals and man. Xenobiotica 29:311–25
  • Reeve E, Wiese MD, Mangoni AA. (2015). Alterations in drug disposition in older adults. Expert Opin Drug Metab Toxicol 11:491–508
  • Riska PS, Joseph DP, Dinallo RM, et al. (1999a). Biotransformation of nevirapine, a non-nucleoside HIV-1 reverse transcriptase inhibitor, in mice, rats, rabbits, dogs, monkeys, and chimpanzees. Drug Metab Dispos 27:1434–47
  • Riska P, Lamson M, Mac Gregor T, et al. (1999b). Disposition and biotransformation of the antiretroviral drug nevirapine in humans. Drug Metab Dispos 27:895–901
  • Roffey SJ, Cole S, Comby P, et al. (2003). The disposition of voriconazole in mouse, rat, rabbit, guinea pig, dog, and human. Drug Metab Dispos 31:731–41
  • Shi S, Klotz U. (2011). Age-related changes in pharmacokinetics. Curr Drug Metab 12:601–10
  • Srinivas NR. (2015a). Interspecies scaling of excretory amounts using allometry – retrospective analysis with rifapentine, aztreonam, carumonam, pefloxacin, miloxacin, trovafloxacin, doripenem, imipenem, cefozopran, ceftazidime, linezolid for urinary excretion and rifapentine, cabotegravir, and dolutegravir for fecal excretion. Xenobiotica. [Epub ahead of print]. DOI: 10.3109/00498254.2015.1121554
  • Srinivas NR. (2015b). Therapeutic drug monitoring of cyclosporine and area under the curve prediction using a single time point strategy: appraisal using peak concentration data. Biopharm Drug Dispos 29:575–86
  • Srinivas NR. (2015c). Differences in the prediction of area under the curve for a protease inhibitor using trough versus peak concentration: assessment using published pharmacokinetic data for indinavir. Am J Ther. [Epub ahead of print]. doi: 10.1097/MJT.0000000000000294
  • Srinivas NR. (2015d). Prediction of area under the curve for a P-glycoprotein, a CYP3A4 and a CYP2C9 substrate using a single time point strategy: assessment using fexofenadine, itraconazole and losartan and metabolites. Drug Dev Ind Pharm 15:1–13
  • Srinivas NR. (2016). Limited sampling strategy for the prediction of area under the curve (AUC) of statins: reliability of a single time point for AUC prediction for pravastatin and simvastatin. Drug Res (Stuttg) 66:82–93
  • Velenosi TJ, Urquhart BL. (2014). Pharmacokinetic considerations in chronic kidney disease and patients requiring dialysis. Expert Opin Drug Metab Toxicol 10:1131–43
  • Weir MR, Fink JC. (2014). Safety of medical therapy in patients with chronic kidney disease and end-stage renal disease. Curr Opin Nephrol Hypertens 23:306–13
  • Xeljanz® (tofacitinib product information). Available at: http://ra.xeljanz.com [last accessed 1 Feb 2016]
  • Zyprexa® (olanzapine product information). Available at: http://pi.lilly.com/us/zyprexa-pi.pdf [last accessed 1 Feb 2016]

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.