LDL cholesterol-lowering effects of grape extract used as a dietary supplement on healthy volunteers

References

• Bashmakov YK, Assaad-Khalil S, Petyaev IM. 2011. Resveratrol may be beneficial in treatment of diabetic foot syndrome. Med Hypotheses. 77 3: 364–367.
   PubMed Web of Science ®Google Scholar
• Boots AW, Haenen RG, Bast A. 2008. Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol. 585:325–337.
   PubMed Web of Science ®Google Scholar
• Di Castelnuovo A, Rotondo S, Iacoviello L, Donati MB, de Gaetano G. 2002. Meta-analysis of wine and beer consumption in relation to vascular risk. Circulation. 105:2836–2844.
   PubMed Web of Science ®Google Scholar
• Fraley AE, Tsimikas S. 2006. Clinical applications of circulating oxidized low-density lipoprotein biomarkers in cardiovascular disease. Curr Opin Lipidol. 17:502–509.
   PubMed Web of Science ®Google Scholar
• Hansen AS, Marckmann P, Dragsted LO, Finne Nielsen IL, Nielsen SE, Gronbaek M. 2005. Effect of red wine and red grape extract on blood lipids, haemostatic factors, and other risk factors for cardiovascular disease. Eur J Clin Nutr. 59:449–455.
   PubMed Web of Science ®Google Scholar
• Ikeda I, Yamahira T, Kato M, Ishikawa A. 2010. Black-tea polyphenols decrease micellar solubility of cholesterol in vitro and intestinal absorption of cholesterol in rats. J Agric Food Chem. 58 15: 8591–8595.
   PubMed Web of Science ®Google Scholar
• Khan N, Monagas M, Andres-Lacueva C, Casas R, Urpí-Sardà M, Lamuela-Raventós RM, Estruch R. 2011. Regular consumption of cocoa powder with milk increases HDL cholesterol and reduces oxidized LDL levels in subjects at high-risk of cardiovascular disease. Nutr Metab Cardiovasc Dis. 22 12: 1–8.
   Web of Science ®Google Scholar
• Lamon-Fava S. 2000. Genistein activates apolipoprotein A–I gene expression in the human hepatoma cell line Hep G2. J Nutr. 130:2489–2492.
   PubMed Web of Science ®Google Scholar
• Lecour S, Lamont KT. 2011. Natural polyphenols and cardioprotection. Mini Rev Med Chem. 11 14: 1191–1199.
   PubMed Web of Science ®Google Scholar
• Leifert WR, Abeywardena MY. 2008. Grape seed and red wine polyphenol extracts inhibit cellular cholesterol uptake, cell proliferation, and 5-lipoxygenase activity. Nutr Res. 28 12: 842–850.
   PubMed Web of Science ®Google Scholar
• Manach C, Mazur A, Scalbert A. 2005. Polyphenols and prevention of cardiovascular diseases. Curr Opin Lipidol. 16 1: 77–84.
   PubMed Web of Science ®Google Scholar
• Mennen LI, Sapinho D, De Bree A, . 2004. Consumption of foods rich in flavonoids is related to a decreased cardiovascular risk in apparently healthy French women. J Nutr. 134:923–926.
   PubMed Web of Science ®Google Scholar
• Mukamal KJ, Maclure M, Muller JE, . 2002. Tea consumption and mortality after acute myocardial infarction. Circulation. 105:2476–2481.
   PubMed Web of Science ®Google Scholar
• Neveu V, Pérez-Jiménez J, Vos F, et al. 2010. Phenol-Explorer: an online comprehensive database on polyphenol contents in foods, Database (Oxford) 2010:bap024.
   Google Scholar
• Ohtsuki K, Abe A, Mitsuzumi H, Kondo M, Uemura K, Iwasaki Y, . 2003. Glucosyl hesperidinim proves serum cholesterol composition and inhibits hypertrophy in vasculature. J Nutr Sci Vitaminol (Tokyo). 49:447–450.
   PubMed Web of Science ®Google Scholar
• Peluzio Mdo C, Teixeira TF, Oliveira VP, Sabarense CM, Dias CM, Abranches MV, Maldonado IR. 2011. Grape extract and α-tocopherol effect in cardiovascular disease model of Apo E− / − mice. Acta Cir Bras. 26 4: 253–260.
   PubMed Web of Science ®Google Scholar
• Perez-Jimenez J, Neveu V, Vos F, Scalbert A. 2010. Systematic analysis of the content of 502 polyphenols in 452 foods and beverages: an application of the Phenol-Explorer database. J Agric Food Chem. 58:4959–4969.
   PubMed Web of Science ®Google Scholar
• Preedy VR, Watson RR, Patel VB. 2011. Nuts and seeds in health and disease prevention. Part 2: effects to specific Nuts and SeedsAcademic Press. Elsevier Inc. ISBN: 9780123756886.
   Google Scholar
• Quideau S, Deffieux D, Douat-Casassus C, Pouységu L. 2011. Plant polyphenols: chemical properties, biological activities, and synthesis. Angew Chem Int Ed Engl. 50 3: 586–621.
   PubMed Web of Science ®Google Scholar
• Rajendran P, Ho E, Williams DE, Dashwood RH. 2011. Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenetics. 3 1: 4.
   PubMedGoogle Scholar
• Räthel TR, Samtleben R, Vollmar AM, Dirsch VM. 2007. Activation of endothelial nitric oxide synthase by red wine polyphenols: impact of grape cultivars, growing area and the vinification process. J Hypertens. 25 3: 541–549.
   PubMed Web of Science ®Google Scholar
• Renaud S, de Lorgeril M. 1992. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet. 339 8808: 1523–1526.
   PubMed Web of Science ®Google Scholar
• Rios LY, Gonthier MP, Remesy C, Mila I, Lapierre C, Lazarus SA, . 2003. Chocolate intake increases urinary excretion of polyphenol-derived phenolic acids in healthy human subjects. Am J Clin Nutr. 77:912–918.
   PubMed Web of Science ®Google Scholar
• Sakurai T, Kitadate K, Nishioka H, Fujii H, Kizaki T, Kondoh Y, . 2010. Oligomerized grape seed polyphenols attenuate inflammatory changes due to antioxidative properties in coculture of adipocytes and macrophages. J Nutr Biochem. 21 1: 47–54.
   PubMed Web of Science ®Google Scholar
• Shen CL, Wang P, Guerrieri J, Yeh JK, Wang JS. 2008. Protective effect of green tea polyphenols on bone loss in middle-aged female rats. Osteoporos Int. 19 7: 979–990.
   PubMed Web of Science ®Google Scholar
• Thomas P, Wang YJ, Zhong JH, Kosaraju S, O'Callaghan NJ, Zhou XF, Fenech M. 2009. Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease. Mutat Res. 661:1–2.
   PubMed Web of Science ®Google Scholar
• Van Acker SA, Tromp MN, Haenen GRMM, van der Vijgh WJ, Bast A. 1995. Flavonoids as scavengers of nitric oxide radical. Biochem Biophys Res Commun. 214:755–759.
   PubMed Web of Science ®Google Scholar
• Wu JM, Hsieh TC. 2011. Resveratrol: a cardioprotective substance. Ann N Y Acad Sci. 1215:16–21.
   PubMed Web of Science ®Google Scholar
• Yang CS, Prabhu S, Landau J. 2001. Prevention of carcinogenesis by tea polyphenols. Drug Metab Rev. 33 3–4: 237–253.
   PubMed Web of Science ®Google Scholar
• Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, . 2004. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 364:937–952.
   PubMed Web of Science ®Google Scholar
• Zern TL, Fernandez ML. 2005. Cardioprotective effects of dietary polyphenols. J Nutr. 135:2291–2294.
   PubMed Web of Science ®Google Scholar