Development of mucoadhesive floating hollow beads of acyclovir with gastroretentive properties

References

• Mertz GJ, Critchlow CW, Benedetti J, et al. Double-blind placebo-controlled trial of oral acyclovir in first-episode genital herpes simplex virus infection. J Am Med Assoc 2011;252:1147–1151
   Google Scholar
• Mindel A, Faherty A, Hindley D, et al. Prophylactic oral acyclovir in recurrent genital herpes. Lancet 1984;324:57–59
   Google Scholar
• Saral R, Burns WH, Laskin OL, et al. Acyclovir prophylaxis against herpes simplex virus infection in patients with leukemia. A randomized, double-blind, placebo-controlled study. Ann Int Med 1983;99:773–776
   PubMed Web of Science ®Google Scholar
• Tao Y, Lu Y, Sun Y, et al. Development of mucoadhesive microspheres of acyclovir with enhanced bioavailability. Int J Pharmaceutics 2009;378:30–36
   PubMed Web of Science ®Google Scholar
• Miranda PD, Blum MR. Pharmacokinetics of acyclovir after intravenous and oral administration. J Antimicrob Chemother 1983;12:29–37
   PubMed Web of Science ®Google Scholar
• British Medical Journal and Royal Pharmaceutical Society. British National Formulary. London: BMJ Publishing Group & RPS Publishing; 2009
   Google Scholar
• Pawar VK, Kansal S, Garg G, et al. Gastroretentive dosage forms: a review with special emphasis on floating drug delivery systems. Drug Deliv 2011;18:97–110
   PubMed Web of Science ®Google Scholar
• Tavakoli N, Varshosaz J, Dorkoosh F, et al. Development and evaluation of a monolithic floating drug delivery system for acyclovir. Chem Pharm Bull 2012;60:172–177
   PubMed Web of Science ®Google Scholar
• Singh BN, Kim KH. Floating drug delivery systems: an approach to oral controlled drug delivrey via gastric retention. J Control Release 2000;63:235–259
   PubMed Web of Science ®Google Scholar
• Junyaprasert VB, Pornsuwannapha S. Floating properties and release characteristics of hollow microspheres of acyclovir. Drug Deliv 2008;15:331–341
   PubMed Web of Science ®Google Scholar
• Ganesh NS, Suraj MA, Ramesh B, Kiran BD. An overview on limitations of gastroretentive drug delivery system. Int J Pharm Sci Rev Res 2011;8:133--139
   Google Scholar
• Hejazi R, Amiji M. Chitosan-based gastrointestinal delivery systems. J Control Release 2003;89:151–165
   PubMed Web of Science ®Google Scholar
• Agnihotri S, Mallikarjuna NN, Aminabhavi TM. Recent advances on chitosan-based micro- and nanoparticles in drug delivery. J Control Release 2004;100:5–28
   PubMed Web of Science ®Google Scholar
• Shiraishi S, Imai T, Otagiri M. Controlled release of indomethacin by chitosan--polyelectrolyte complex: optimisation and in vivo/in vitro evaluation. J Control Release 1993;25:217–225
   Web of Science ®Google Scholar
• El-Gibaly I. Development and in vitro evaluation of novel floating chitosan microcapsules for oral use: comparison with non-floating chitosan microspheres. Int J Pharmaceutics 2002;249:7–21
   PubMed Web of Science ®Google Scholar
• Yang H-C, Hon M-H. The effect of the molecular weight of chitosan nanoparticles and its application on drug delivery. Microchem J 2009;92:87–91
   Web of Science ®Google Scholar
• Rokhade AP, Patil SA, Aminabhavi TM. Synthesis and characterization of semi-interpenetrating polymer network microspheres of acrylamide grafted dextran and chitosan for controlled release of acyclovir. Carbohydr Polym 2007;67:605–613
   Web of Science ®Google Scholar
• Sinha VR, Singla AK, Wadhawan S, et al. Chitosan microspheres as a potential carrier for drugs. Int J Pharmaceutics 2004;274:1–33
   PubMed Web of Science ®Google Scholar
• Abreu FOMS, Bianchini C, Forte MMC, Kist TBL. Influence of the composition and preparation method on the morphology and swelling behavior of alginate-chitosan hydrogels. Carbohydr Polymers 2008;74:283–289
   Google Scholar
• Dhaliwal S, Jain S, Singh HP, Tiwary A. Mucoadhesive microspheres for gastroretentive delivery of acyclovir: in vitro and in vivo evaluation. AAPS J 2008;10:332–330
   Google Scholar
• Sinko PJ, ed. Martin’s physical pharmacy and pharmaceutical sciences. Baltimore: Lippincott Williams & Wilkins; 2006
   Google Scholar
• Gandhi N, Shirolkar S, Tawar M. Development and evaluation of microballoons of pioglitazone hydrochloride using eudragit S-100. Int J Pharm Sci Res 2012;3:201–212
   Google Scholar
• Kawashima Y, Niwa T, Takeuchi H, et al. Hollow microspheres for use as a floating controlled drug delivery system in the stomach. J Pharm Sci 1992;81:135–140
   PubMed Web of Science ®Google Scholar
• Mello KGPCD, Bernusso LDC, Potombo RNDM, Polakiewicz B. Synthesis and physicochemical characterizatin of chemically modified chitosan by succinic anhydride. Braz Archiv Biol Technol 2006;49:665–668
   Google Scholar
• Kumar MNVR, Muzzarelli RAA, Muzzarelli C, et al. Chitosan chemistry and pharmaceutical perspectives. Chem Rev 2004;104:6017–6084
   PubMed Web of Science ®Google Scholar
• Shah SH, Patel JK, Patel NV. Stomach specific floating drug delivery system: a review. Int J PharmTech Res 2009;1:623–633
   Google Scholar
• Ford JL, Rubinstein MH, Hogan JE. Formulation of sustained release promethazine hydrochloride tablets using hydroxypropylmethylcellulose matrices. Int J Pharmaceutics 1985;24:327–338
   Web of Science ®Google Scholar
• Ishak RAH, Awad GAS, Mortada ND, Nour SAK. Preparation, in vitro and in vivo evaluation of stomach-specific metronidazole-loaded alginate beads as local anti-Helicobacter pylori therapy. J Control Release 2007;119:207–214
   PubMed Web of Science ®Google Scholar