Correlations between lower urinary tract symptoms, erectile dysfunction, and cardiovascular diseases: Are there differences between male populations from primary healthcare and urology clinics? A review of the current knowledge

References

• Holden CA, McLachlan RI, Pitts M, Cumming R, Wittert G, Agius PA, . Men in Australia telephone survey (MaTeS): a national study of the reproductive health and concerns of middle aged and older Australian men. Lancet 2005; 366:218–24.
   PubMed Web of Science ®Google Scholar
• Zakaria L, Aristotelis GA, Shabsigh R. Common conditions of the aging male: erectile dysfunction, benign prostatic hyperplasia, cardiovascular disease and depression. Int Urol Nephrol 2001; 33:283–92.
   PubMedGoogle Scholar
• Rosen RC. Reproductive health problems in ageing men. Lancet 2005; 366:183–4.
   PubMed Web of Science ®Google Scholar
• Fitzgerald MP, Link CL, Litman HJ, Travison TG, McKinlay JB. Beyond the lower urinary tract: the association of urologic and sexual symptoms with common illnesses. Eur Urol 2007; 52:407–15.
   PubMed Web of Science ®Google Scholar
• McVary KT. BPH: epidemiology and comorbidities. Am J Manag Care 2006; 12:S122–8.
   PubMed Web of Science ®Google Scholar
• Batista-Miranda JE, Molinuevo B, Pardo Y. Impact of lower urinary tract symptoms on quality of life using functional assessment cancer therapy scale. Urology 2007; 69:285–8.
   PubMed Web of Science ®Google Scholar
• Kok ET, Bohnen AM, Groeneveld FPMJ, Busschbach JJ, Blanker M, Bosch R. Changes in disease specific and generic quality of life related to changes in lower urinary tract symptoms: the Krimpen study. J Urol 2005; 174:1055–8.
   PubMed Web of Science ®Google Scholar
• Roberston C, Link CL, Onel E, Mazzetta C, Keech M, Hobbs R, . The impact of lower urinary tract symptoms and comorbidities on quality of life: the BACH and UREPIK studies. BJU Int 2007; 99:347–54.
   PubMed Web of Science ®Google Scholar
• Thompson IM, Tangen CM, Goodman PJ, Probstfield JL, Moinpour CM, Coltman CA. Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005; 294:2996–3002.
   PubMed Web of Science ®Google Scholar
• NIH Consensus Development Panel on Impotence. Impotence [NIH Consensus Conference]. JAMA 1993; 270:83–90.
   PubMed Web of Science ®Google Scholar
• Jardin A, Wagner G, Khoury S, Giuliani F, Goldstein I, Padma-Nathan H, . Recommendations of the 1st international consultation on erectile dysfunctionCosponsored by the World Health Organization, International Consultation on Urologic Diseases, and Société Internationale dÚrolgie. World Health Organization;Geneva1999; :p. 709–26.
   Google Scholar
• Shabsigh R, Anastasiadis AG. Erectile dysfunction. Annu Rev Med 2003; 54:153–68.
   PubMed Web of Science ®Google Scholar
• Leusink P, De Boer LJ, Vliet Vlieland CW, Rambharose VR, Sprengers AM, Mogendorff SW, . NHG standaard Erectiele disfunctie. Huisarts Wet 2008; 51:381–94.
   Google Scholar
• Chew KK, Earle CM, Stuckey BGZ, Jamrozik K, Keogh EJ. Erectile dysfunction in general medicine practice: prevalence and clinical correlates. Int J Impot Res 2000; 12:41–5.
   PubMed Web of Science ®Google Scholar
• Ganz P. Erectile dysfunction: pathophysiologic mechanisms pointing to underlying cardiovascular disease. Am J Cardiol 2005; 96 Suppl:8M–12M.
   Google Scholar
• Russel ST, Khandheria BK, Nehra A. Erectile dysfunction and cardiovascular disease. Mayo Clin Proc 2004; 79:782–94.
   PubMed Web of Science ®Google Scholar
• Miner MM, Kuritzky L. Erectile dysfunction: a sentinel marker for cardiovascular disease in primary care. Cleve Clin J Med 2007; 74 Suppl 3:S30–7.
   Google Scholar
• Watts GF, Chew KK, Stuckey BGA. The erectile-endothelial dysfunction nexus: new opportunities for cardiovascular risk prevention. Nat Clin Pract Cardiovasc Med 2007; 4:263–73.
   PubMedGoogle Scholar
• De Boer BJ, Bots ML, Lycklama a Nijeholt AA, Moors JP, Pieters HM, Verheij TJ. Erectile dysfunction in primary care: prevalence and patient characteristics. The ENIGMA study. Int J Impot Res 2004; 16:358–64.
   PubMed Web of Science ®Google Scholar
• Burnett AL. Erectile dysfunction. J Urol 2006; 175:S25–31.
   PubMed Web of Science ®Google Scholar
• Vicari E, Arcidiacono G, Di Pino L, Signorelli S, Arancio A, Sorrentino F, . Incidence of extragenital vascular disease in patients with erectile dysfunction of arterial origin. Int J Impot Res 2005; 17:277–82.
   PubMed Web of Science ®Google Scholar
• Stuckey BGA, Walsh JP, Ching HL, Stuckey AW, Palmer NR, Thompson PL, . Erectile dysfunction predicts generalized cardiovascular disease: evidence from a case-control study. Atherosclerosis 2007; 194:458–64.
   PubMed Web of Science ®Google Scholar
• Barry MJ, O'Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK, . The American Urological Association symptom index for benign prostatic hyperplasia. J Urol 1992; 148:1549–57.
   PubMed Web of Science ®Google Scholar
• Blanker MH, Bohnen AM, Groeneveld FPMJ, Prins A, Thomas S, . Correlates for erectile and ejaculatory dysfunction in older Dutch men: a community-based study. JAGS 2001; 49:436–42.
   PubMed Web of Science ®Google Scholar
• Braun MH, Sommer F, Haupt G, Mathers MJ, Reigenrath B, Engelmann UH. Lower urinary tract symptoms and erectile dysfunction: co-morbidity or typical ‘aging male’ symptoms? Results of the ‘Cologne Male Survey’. Eur Urol 2003; 44:588–94.
   PubMed Web of Science ®Google Scholar
• Mariappan P, Chong WL. Prevalence and correlates of lower urinary tract symptoms, erectile dysfunction and incontinence in men from a multiethnic Asian population: results of a regional population-based survey and comparison with industrialized nations. BJU Int 2006; 98:1264–8.
   PubMed Web of Science ®Google Scholar
• Rosen R, Altwein J, Boyle P, Kirby RS, Lukacs B, Meuleman E, . Lower urinary tract symptoms and male sexual dysfunction: the Multinational Survey of the Aging Male (MSAM-7). Eur Urol 2003; 44:637–49.
   PubMed Web of Science ®Google Scholar
• Li MK, Lester A, Garcia A, Rosen R. Lower urinary tract symptoms and male sexual dysfunction in Asia: a survey of ageing men from five Asian countries. BJU Int 2005; 96:1339–54.
   PubMed Web of Science ®Google Scholar
• Shabsigh R, Perelman MA, Lockhart DC, Lue TF, Broderick GA. Health issues of men: prevalence and correlates of erectile dysfunction. J Urol 2005; 174:662–7.
   PubMed Web of Science ®Google Scholar
• Boyle P, Robertson C, Mazzetta C, Keech M, Hobbs R, Fourcade R, . The association between lower urinary tract symptoms and erectile dysfunction in four centres: the UrEpik study. BJU Int 2003; 92:719–25.
   PubMed Web of Science ®Google Scholar
• Nicolosi A, Glasser DB, Moreira ED, Villa M. Prevalence of erectile dysfunction and associated factors among men without concomitant diseases: a population study. Int J Impot Res 2003; 15:253–7.
   PubMed Web of Science ®Google Scholar
• Glina S, Santana AW, Azank F, Mello LF, Moreira ED. Lower urinary tract symptoms and erectile dysfunction are highly prevalent in ageing men. BJU Int 2005; 97:763–5.
   Web of Science ®Google Scholar
• Terai A, Ichioka K, Matsui Y, Yoshimura K. Association of lower urinary tract symptoms with erectile dysfunction in Japanese men. Urology 2004; 64:132–6.
   PubMed Web of Science ®Google Scholar
• Cappelleri JC, Rosen RC. The Sexual Health Inventory for Men (SHIM): a 5-year review of research and clinical experience. Int J Impot Res 2005; 17:307–19.
   PubMed Web of Science ®Google Scholar
• Shiri R, Häkkinen JT, Hakama M, Huhtala H, Auvinen A, Tammela TL, . Effect of lower urinary tract symptoms on the incidence of erectile dysfunction. J Urol 2005; 174:205–9.
   PubMed Web of Science ®Google Scholar
• Ströberg P, Boman H, Gellerstedt M, Hedelin H. Relationships between lower urinary tract symptoms, the bother they induce and erectile dysfunction. Scand J Urol Nephrol 2006; 40:307–12.
   PubMed Web of Science ®Google Scholar
• Elliot SP, Gulati M, Pasta DJ, Spitalny GM, Kane CJ, Yee R, . Obstructive lower urinary tract symptoms correlate with erectile dysfunction. Urology 2004; 63:1148–52.
   PubMed Web of Science ®Google Scholar
• El Sakka AI. Lower urinary tract symptoms in patients with erectile dysfunction: is there a vascular association?. Eur Urol 2005; 48:319–25.
   PubMed Web of Science ®Google Scholar
• Rosen RC, Cappelleri JC, Smith MD, Lipsky J, Peña BM. Development and evaluation of an abridged, 5-item version of the international index of erectile function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res 1999; 11:319–26.
   PubMed Web of Science ®Google Scholar
• Atan A, Basar MM, Tuncel A, Mert C, Aslan Y. Is there a relationship among age, international index of erectile function, international prostate symptom score, and aging males’ symptom score?. Int Urol Nephrol 2007; 39:215–22.
   PubMed Web of Science ®Google Scholar
• Liu CC, Huang SP, Wang CJ, Wu WJ, Chou YH, Huang CH. Are lower urinary tract symptoms associated with erectile dysfunction in aging males of Taiwan?. Urol Int 2006; 77:251–4.
   PubMed Web of Science ®Google Scholar
• Ponholzer A, Temml C, Obermayr R, Madersbacher S. Association between lower urinary tract symptoms and erectile dysfunction. Urology 2004; 64:772–6.
   PubMed Web of Science ®Google Scholar
• Vallancien G, Emberton M, Harving N, Moorselaar RJA. Sexual dysfunction in 1,274 European men suffering from lower urinary tract symptoms. J Urol 2003; 169:2257–61.
   PubMed Web of Science ®Google Scholar
• Billups KL. Erectile dysfunction as an early sign of cardiovascular disease. Int J Impot Res 2005; 17:S19–24.
   PubMedGoogle Scholar
• Solomon H, Man JW, Jackson G. Erectile dysfunction and the cardiovascular patient: endothelial dysfunction is the common denominator. Heart 2003; 89:251–3.
   PubMed Web of Science ®Google Scholar
• Solomon H, DeBusk RF, Jackson G. Erectile dysfunction: the need to be evaluated, the right to be treated. Am Heart J 2005; 150:620–6.
   PubMed Web of Science ®Google Scholar
• Vlachopoulos C, Rokkas K, Kerbis Y, Aggeli C, Michaelides A, Roussakis G, . Prevalence of asymptomatic coronary artery disease in men with vasculogenic erectile dysfunction: a prospective angiographic study. Eur Urol 2005; 48:996–1002.
   PubMed Web of Science ®Google Scholar
• Moinpour CM, Lovato LC, Thompson IM, Ware JE, Ganz PA, Patrick DL, . Profile of men randomized to the prostate cancer prevention trial: baseline health-related quality of life, urinary and sexual functioning, and health behaviors. J Clin Oncol 2000; 18:1942–53.
   PubMed Web of Science ®Google Scholar
• Travison TG, Shabsigh R, Araujo AB, Kupelian V, O'Donnel AB, McKinlay JB. The natural progression and remission of erectile dysfunction: results from the Massachusetts Male Aging Study. J Urol 2007; 177:241–6.
   PubMed Web of Science ®Google Scholar
• Frantzen J, Speel TGW, Kiemeney LA, Meuleman EJH. Cardiovascular risk among men seeking help for erectile dysfunction. Ann Epidemiol 2006; 16:85–90.
   PubMed Web of Science ®Google Scholar
• Jackson G, Rosen RC, Kloner RA, Kostis JB. The second Princeton consensus on sexual dysfunction and cardiac risk: new guidelines for sexual medicine. J Sex Med 2006; 3:28–36.
   PubMed Web of Science ®Google Scholar
• Chitale S, Collins R, Hull S, Smith E, Irving S. Is the current practice providing an integrated approach to the management of LUTS and ED in primary care? An audit and literature review. J Sex Med 2007; 4:1713–25.
   PubMed Web of Science ®Google Scholar
• Burgers JS, Simoons ML, Hoes AW, Stehouwer CD, Stalman WA. Guideline ‘cardiovascular risk management’. Ned Tijdschr Geneeskd 2007; 151:1068–74.
   PubMedGoogle Scholar
• Van Der Heide WK. General practitioners care for men with urine problems. Dissertation Gromingen, The Netherlands 2006.
   Google Scholar
• Conroy RM, Pyorala K, Fitzgerald AP, Sans S, Menotti A, De Backer G, . Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003; 24:987–1003.
   PubMed Web of Science ®Google Scholar