A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [¹⁴C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [¹³C₆]-labeled basimglurant in humans

Elena GueriniRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and Correspondence[email protected]

Simone SchadtRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and

Gerard GreigRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and

Ruth HaasRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and

Christophe HusserRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and

Manfred ZellRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and

Christoph FunkRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and

Thomas HartungRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and

Andreas GlogeRoche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland and

Navita L. MallalieuRoche Pharmaceutical Research and Early Development, Roche Innovation Center NYC, NY, USA

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A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [¹⁴C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [¹³C₆]-labeled basimglurant in humans

IXEN_1169334_Supplementary_Material.pdf

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A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [14C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [13C6]-labeled basimglurant in humans

IXEN_1169334_Supplementary_Material.pdf

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A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [¹⁴C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [¹³C₆]-labeled basimglurant in humans