Drug Development and Industrial Pharmacy, Volume 42, Issue 2 (2016)

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Drug Development and Industrial Pharmacy, Volume 42, Issue 2 (2016)

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Review article

Review Article
A quality by design approach to scale-up of high-shear wet granulation process
Preetanshu Pandey & Sherif Badawy
Pages: 175-189
Published online: 22 Oct 2015
AbstractforA quality by design approach to scale-up of high-shear wet granulation process | Full Text | References | PDF (556.2 KB)
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Original Articles

Article
Lipid nanoparticles as an emerging platform for cannabinoid delivery: physicochemical optimization and biocompatibility
M. Durán-Lobato, L. Martín-Banderas, R. Lopes, L. M. D. Gonçalves, M. Fernández-Arévalo & A. J. Almeida
Pages: 190-198
Published online: 21 May 2015
AbstractforLipid nanoparticles as an emerging platform for cannabinoid delivery: physicochemical optimization and biocompatibility | Full Text | References | PDF (575.1 KB)
  • 717 Views
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Research Article

Article
Development of novel core-shell dual-mesoporous silica nanoparticles for the production of high bioavailable controlled-release fenofibrate tablets
Zongzhe Zhao, Yu Gao, Chao Wu, Yanna Hao, Ying Zhao & Jie Xu
Pages: 199-208
Published online: 26 Jun 2015
AbstractforDevelopment of novel core-shell dual-mesoporous silica nanoparticles for the production of high bioavailable controlled-release fenofibrate tablets | Full Text | References | PDF (1.4 MB)
  • 350 Views
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Article
Chlorogenic acid stabilized nanostructured lipid carriers (NLC) of atorvastatin: formulation, design and in vivo evaluation
Saba Khan, Sanjula Baboota, Javed Ali, R. S. Narang & Jasjeet K. Narang
Pages: 209-220
Published online: 27 May 2015
AbstractforChlorogenic acid stabilized nanostructured lipid carriers (NLC) of atorvastatin: formulation, design and in vivo evaluation | Full Text | References | PDF (1 MB)
  • 390 Views
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Article
Development of a design space and predictive statistical model for capsule filling of low-fill-weight inhalation products
E. Faulhammer, M. Llusa, P. R. Wahl, A. Paudel, S. Lawrence, S. Biserni, V. Calzolari & J. G. Khinast
Pages: 221-230
Published online: 29 May 2015
AbstractforDevelopment of a design space and predictive statistical model for capsule filling of low-fill-weight inhalation products | Full Text | References | PDF (582.8 KB)
  • 283 Views
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Article
Viscoelastic interactions between polydeoxyribonucleotide and ophthalmic excipients
Iksoo Kim, Hyeongmin Kim, Kyunghee Park, Sandeep Karki, Prakash Khadka, Kanghee Jo, Seong Yeon Kim, Jieun Ro & Jaehwi Lee
Pages: 231-237
Published online: 29 May 2015
AbstractforViscoelastic interactions between polydeoxyribonucleotide and ophthalmic excipients | Full Text | References | PDF (740.5 KB)
  • 267 Views
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Article
Solid-state stability studies of crystal form of tebipenem
Alicja Talaczyńska, Kornelia Lewandowska, Piotr Garbacki, Przemysław Zalewski, Robert Skibiński, Andrzej Miklaszewski, Mikołaj Mizera & Judyta Cielecka-Piontek
Pages: 238-244
Published online: 05 Jun 2015
AbstractforSolid-state stability studies of crystal form of tebipenem | Full Text | References | PDF (869.6 KB)
  • 180 Views
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Article
Enhanced colonic delivery of ciclosporin A self-emulsifying drug delivery system encapsulated in coated minispheres
Kieran Keohane, Mónica Rosa, Ivan S. Coulter & Brendan T. Griffin
Pages: 245-253
Published online: 17 Jun 2015
AbstractforEnhanced colonic delivery of ciclosporin A self-emulsifying drug delivery system encapsulated in coated minispheres | Full Text | References | PDF (485 KB)
  • 528 Views
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Article
Topical delivery of leflunomide for rheumatoid arthritis treatment: evaluation of local tissue deposition of teriflunomide and its anti-inflammatory effects in an arthritis rat model
Joonho Bae & Jin Woo Park
Pages: 254-262
Published online: 26 May 2015
AbstractforTopical delivery of leflunomide for rheumatoid arthritis treatment: evaluation of local tissue deposition of teriflunomide and its anti-inflammatory effects in an arthritis rat model | Full Text | References | PDF (503.2 KB)
  • 413 Views
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Article
Metabolic interactions of magnolol with cytochrome P450 enzymes: uncompetitive inhibition of CYP1A and competitive inhibition of CYP2C
Sang-Bum Kim, Hee Eun Kang, Hyun-Jong Cho, Yeong Shik Kim, Suk-Jae Chung, In-Soo Yoon & Dae-Duk Kim
Pages: 263-269
Published online: 02 Jul 2015
AbstractforMetabolic interactions of magnolol with cytochrome P450 enzymes: uncompetitive inhibition of CYP1A and competitive inhibition of CYP2C | Full Text | References | PDF (384.6 KB)
  • 462 Views
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Article
Sustained release of diltiazem HCl tableted after co-spray drying and physical mixing with PVAc and PVP
Nizar Al-Zoubi, Ghada Al-obaidi, Bassam Tashtoush & Stavros Malamataris
Pages: 270-279
Published online: 02 Jun 2015
AbstractforSustained release of diltiazem HCl tableted after co-spray drying and physical mixing with PVAc and PVP | Full Text | References | PDF (1.8 MB)
  • 203 Views
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Article
Development and in vitro–in vivo evaluation of a water-in-oil microemulsion formulation for the oral delivery of troxerutin
Man Xu, Qing Yu, Qianru Zhao, Wei Chen, Yuanjie Lin & Yong Jin
Pages: 280-287
Published online: 13 Jul 2015
AbstractforDevelopment and in vitro–in vivo evaluation of a water-in-oil microemulsion formulation for the oral delivery of troxerutin | Full Text | References | PDF (897.5 KB)
  • 248 Views
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Article
Fabrication of lipidic nanocarriers of loratadine for facilitated intestinal permeation using multivariate design approach
Samridhi Verma, Sandeep Kumar Singh & Priya Ranjan Prasad Verma
Pages: 288-306
Published online: 19 Jun 2015
AbstractforFabrication of lipidic nanocarriers of loratadine for facilitated intestinal permeation using multivariate design approach | Full Text | References | PDF (2.7 MB) | Supplemental
  • 182 Views
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Article
Phytantriol based liquid crystal provide sustained release of anticancer drug as a novel embolic agent
Lingzhen Qin, Liling Mei, Ziyun Shan, Ying Huang, Xin Pan, Ge Li, Yukun Gu & Chuanbin Wu
Pages: 307-316
Published online: 02 Jun 2015
AbstractforPhytantriol based liquid crystal provide sustained release of anticancer drug as a novel embolic agent | Full Text | References | PDF (2.1 MB)
  • 374 Views
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Article
The protective effects of apocynin on ionizing radiation-induced intestinal damage in rats
Y. F. Cagin, H. Parlakpinar, A. Polat, N. Vardi, Y. Atayan, M. A. Erdogan, K. Ekici, A. Yildiz, M. E. Sarihan & H. Aladag
Pages: 317-324
Published online: 15 Jun 2015
AbstractforThe protective effects of apocynin on ionizing radiation-induced intestinal damage in rats | Full Text | References | PDF (1.9 MB)
  • 454 Views
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Article
P-glycoprotein inhibition of drug resistant cell lines by nanoparticles
Manu Smriti Singh & Alf Lamprecht
Pages: 325-331
Published online: 11 Jun 2015
AbstractforP-glycoprotein inhibition of drug resistant cell lines by nanoparticles | Full Text | References | PDF (438.1 KB)
  • 355 Views
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Article
Floating modular drug delivery systems with buoyancy independent of release mechanisms to sustain amoxicillin and clarithromycin intra-gastric concentrations
Alessandra Rossi, Chiara Conti, Gaia Colombo, Luca Castrati, Carmelo Scarpignato, Pedro Barata, Giuseppina Sandri, Carla Caramella, Ruggero Bettini, Francesca Buttini & Paolo Colombo
Pages: 332-339
Published online: 11 Jun 2015
AbstractforFloating modular drug delivery systems with buoyancy independent of release mechanisms to sustain amoxicillin and clarithromycin intra-gastric concentrations | Full Text | References | PDF (575.6 KB)
  • 216 Views
  • 16 CrossRef citations
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Article
Designing of the fixed-dose gastroretentive bilayer tablet for sustained release of metformin and immediate release of atorvastatin
Ju-Hee Oh, Ji Eun Lee, Yu Jeong Kim, Tack-Oon Oh, SungKyun Han, Eun Kyung Jeon, Kyungmin Shin, Dong-Hyun Kim, Chi Hye Park & Young-Joo Lee
Pages: 340-349
Published online: 15 Oct 2015
AbstractforDesigning of the fixed-dose gastroretentive bilayer tablet for sustained release of metformin and immediate release of atorvastatin | Full Text | References | PDF (973.2 KB)
  • 410 Views
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