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Volume 24, Issue 5

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 24, Issue 5 (2015)

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Expert Opinion on Investigational Drugs, Volume 24, Issue 5 (2015)

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Vol 33, 2024 Vol 32, 2023 Vol 31, 2022 Vol 30, 2021 Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Volume 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Vol 20, 2011 Vol 19, 2010 Vol 18, 2009 Vol 17, 2008 Vol 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 Vol 12, 2003 Vol 11, 2002 Vol 10, 2001 Vol 9, 2000 Vol 8, 1999 Vol 7, 1998 Vol 6, 1997 Vol 5, 1996 Vol 4, 1995 Vol 3, 1994

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Editorial

Prospects for early investigational therapies for sickle cell disease

Nicola Conran

Pages: 595-602

Published online: 15 Feb 2015

AbstractforProspects for early investigational therapies for sickle cell disease | Full Text | References | PDF (278.1 KB)

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Review

Fibroblast growth factor 19-targeted therapies for the treatment of metabolic disease

Jacek Rysz (Professor) MD PhD FASN, Anna Gluba-Brzózka, Dimitri P Mikhailidis & Maciej Banach

Pages: 603-610

Published online: 21 Jan 2015

AbstractforFibroblast growth factor 19-targeted therapies for the treatment of metabolic disease | Full Text | References | PDF (298.1 KB)

443 Views
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Early investigational drugs targeting PPAR-α for the treatment of metabolic disease

Zhong-Min Liu MD PhD, Miao Hu (Research Assistant Professor) PhD, Paul Chan (Consultant Cardiologist) MD PhD & Brian Tomlinson (Professor of Medicine and Therapeutics) MBBS MD

Pages: 611-621

Published online: 21 Jan 2015

AbstractforEarly investigational drugs targeting PPAR-α for the treatment of metabolic disease | Full Text | References | PDF (399.6 KB)

944 Views
39 CrossRef citations
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Phase II anti-inflammatory and immune-modulating drugs for acute ischaemic stroke

Craig J Smith MD MRCP, Adam Denes PhD, Pippa J Tyrrell MD FRCP & Mario Di Napoli MD

Pages: 623-643

Published online: 01 Mar 2015

AbstractforPhase II anti-inflammatory and immune-modulating drugs for acute ischaemic stroke | Full Text | References | PDF (485.7 KB)

551 Views
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Investigational drugs for the treatment of spinal cord injury: review of preclinical studies and evaluation of clinical trials from Phase I to II

Narihito Nagoshi & Michael G Fehlings

Pages: 645-658

Published online: 03 Feb 2015

AbstractforInvestigational drugs for the treatment of spinal cord injury: review of preclinical studies and evaluation of clinical trials from Phase I to II | Full Text | References | PDF (481.1 KB)

790 Views
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Investigational drugs under development for the treatment of PTSD

Benjamin J Ragen, Jordan Seidel, Christine Chollak, Robert H Pietrzak & Alexander Neumeister (Professor of Psychiatry and Radiology, Director) MD

Pages: 659-672

Published online: 14 Mar 2015

AbstractforInvestigational drugs under development for the treatment of PTSD | Full Text | References | PDF (467.2 KB)

999 Views
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Investigational therapies up to Phase II which target PDGF receptors: potential anti-cancer therapeutics

Jennifer Arrondeau, Olivier Huillard, Camille Tlemsani, Anatole Cessot, Pascaline Boudou-Rouquette, Benoit Blanchet, Audrey Thomas-Schoemann, Michel Vidal, Jean-Marie Tigaud, Jean-Philippe Durand, Jerome Alexandre & Francois Goldwasser

Pages: 673-687

Published online: 20 Jan 2015

AbstractforInvestigational therapies up to Phase II which target PDGF receptors: potential anti-cancer therapeutics | Full Text | References | PDF (404.3 KB)

360 Views
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Investigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections

Burhan A Khan (Post-baccalaureate IRTA) BS, Anthony J Yeh (Post-baccalaureate IRTA) BS, Gordon Yc Cheung (Staff Scientist) PhD & Michael Otto (Senior Investigator) PhD

Pages: 689-704

Published online: 23 Feb 2015

AbstractforInvestigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections | Full Text | References | PDF (567.6 KB)

879 Views
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Drug Evaluation

The use of agomelatine in OCD: effects on the motivational aspects and dysregulated circadian rhythms

Giulio Perugi MD, Giuseppe Quaranta MD & Nunzio Bucci MD

Pages: 705-713

Published online: 01 Mar 2015

AbstractforThe use of agomelatine in OCD: effects on the motivational aspects and dysregulated circadian rhythms | Full Text | References | PDF (297 KB)

354 Views
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Blinatumomab for the treatment of B-cell lymphoma

Eunhye Oak BA & Nancy L Bartlett (Professor of Medicine, Koman Chair in Medical Oncology) MD

Pages: 715-724

Published online: 04 Mar 2015

AbstractforBlinatumomab for the treatment of B-cell lymphoma | Full Text | References | PDF (298.6 KB)

1134 Views
25 CrossRef citations
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Ezatiostat hydrochloride for the treatment of myelodysplastic syndromes

Daruka Mahadevan MD PhD & Gregory Ryan Sutton MD

Pages: 725-733

Published online: 27 Feb 2015

AbstractforEzatiostat hydrochloride for the treatment of myelodysplastic syndromes | Full Text | References | PDF (459.1 KB)

370 Views
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Erratum

Correction

Erratum

Page: 735

Published online: 13 Mar 2015

CitationforErratum | Full Text | PDF (30.6 KB)

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