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Volume 12, Issue 7

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 12, Issue 7 (2016)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 12, Issue 7 (2016)

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Editorial

Effect of aging on pain relief in the older cancer patients: pharmacokinetic and pharmacodynamic aspects

Sebastiano Mercadante, Alessandro Mercadante & Federica Aielli

Pages: 711-713

Published online: 27 Feb 2016

First Page PreviewforEffect of aging on pain relief in the older cancer patients: pharmacokinetic and pharmacodynamic aspects | Full Text | References | PDF (244 KB)

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Free Access

Original Research

Article

A short-term high fat diet increases exposure to midazolam and omeprazole in healthy subjects

Roos Achterbergh, Laureen A. Lammers, Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Ron A. A. Mathôt & Johannes A. Romijn

Pages: 715-720

Published online: 03 Jun 2016

AbstractforA short-term high fat diet increases exposure to midazolam and omeprazole in healthy subjects | Full Text | References | PDF (645.2 KB)

1609 Views
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Open Access

Review

Drug interactions between buprenorphine, methadone and hepatitis C therapeutics

Onyema Ogbuagu, Gerald Friedland & R. Douglas Bruce

Pages: 721-731

Published online: 30 May 2016

AbstractforDrug interactions between buprenorphine, methadone and hepatitis C therapeutics | Full Text | References | PDF (831.3 KB)

575 Views
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Review

Pharmacogenetics of tyrosine kinase inhibitors in gastrointestinal stromal tumor and chronic myeloid leukemia

Gloria Ravegnini, Giulia Sammarini, Sabrina Angelini & Patrizia Hrelia

Pages: 733-742

Published online: 17 May 2016

AbstractforPharmacogenetics of tyrosine kinase inhibitors in gastrointestinal stromal tumor and chronic myeloid leukemia | Full Text | References | PDF (961.8 KB)

324 Views
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Review

The forgotten or underestimated relevance of biopharmaceutical-based assessments for the oral absorption studies of oxime reactivators

Victor A. Voicu, Andrei Valentin Medvedovici, Koichi Sakurada, Hikoto Ohta, Flavian Ștefan Rădulescu & Dalia Simona Miron

Pages: 743-752

Published online: 04 May 2016

AbstractforThe forgotten or underestimated relevance of biopharmaceutical-based assessments for the oral absorption studies of oxime reactivators | Full Text | References | PDF (729.9 KB)

81 Views
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Review

Alleviation of pain in painful diabetic neuropathy

János Tajti, Délia Szok, Zsófia Majláth, Anett Csáti, Anna Petrovics-Balog & László Vécsei

Pages: 753-764

Published online: 25 May 2016

AbstractforAlleviation of pain in painful diabetic neuropathy | Full Text | References | PDF (994.9 KB)

756 Views
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Review

Insights into the pharmacokinetic properties of antitubercular drugs

Mahendra Shukla, Abhisheak Sharma, Swati Jaiswal & Jawahar Lal

Pages: 765-778

Published online: 17 May 2016

AbstractforInsights into the pharmacokinetic properties of antitubercular drugs | Full Text | References | PDF (1.4 MB)

291 Views
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Review

Metabolic impact of combined hormonal contraceptives containing estradiol

Giovanni Grandi, Antonella Napolitano & Angelo Cagnacci

Pages: 779-787

Published online: 01 Jun 2016

AbstractforMetabolic impact of combined hormonal contraceptives containing estradiol | Full Text | References | PDF (832.6 KB)

488 Views
35 CrossRef citations
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Review

Hepatotoxicity of targeted therapy for cancer

Kirsty Wai-Chung Lee & Stephen Lam Chan

Pages: 789-802

Published online: 06 Jun 2016

AbstractforHepatotoxicity of targeted therapy for cancer | Full Text | References | PDF (1,015.1 KB)

902 Views
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Drug Evaluation

Article

Pharmacodynamics, pharmacokinetics and clinical efficacy of telavancin in the treatment of pneumonia

Liapikou Adamantia & Torres Antoni

Pages: 803-812

Published online: 30 May 2016

AbstractforPharmacodynamics, pharmacokinetics and clinical efficacy of telavancin in the treatment of pneumonia | Full Text | References | PDF (936.2 KB)

173 Views
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Article

Pharmacodynamic and pharmacokinetic assessment of fluticasone furoate + vilanterol for the treatment of asthma

Luigino Calzetta, Barbara Rinaldi, Mario Cazzola & Maria Gabriella Matera

Pages: 813-822

Published online: 09 Jun 2016

AbstractforPharmacodynamic and pharmacokinetic assessment of fluticasone furoate + vilanterol for the treatment of asthma | Full Text | References | PDF (751 KB)

577 Views
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Article

Pharmacokinetic and pharmacodynamic evaluation of oxycodone and naltrexone for the treatment of chronic lower back pain

Mellar P. Davis

Pages: 823-831

Published online: 07 Jun 2016

AbstractforPharmacokinetic and pharmacodynamic evaluation of oxycodone and naltrexone for the treatment of chronic lower back pain | Full Text | References | PDF (703.2 KB)

535 Views
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Article

Pharmacodynamic assessment of vedolizumab for the treatment of ulcerative colitis

Leon P. McLean & Raymond K. Cross

Pages: 833-842

Published online: 12 May 2016

AbstractforPharmacodynamic assessment of vedolizumab for the treatment of ulcerative colitis | Full Text | References | PDF (879.7 KB)

418 Views
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Erratum

Correction

Erratum

Page: v

Published online: 03 Jun 2016

CitationforErratum | Full Text | PDF (84.7 KB)

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