Expert Opinion on Drug Metabolism & Toxicology, Volume 17, Issue 6 (2021)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Expert Opinion on Drug Metabolism & Toxicology, Volume 17, Issue 6 (2021)

See all volumes and issues
Vol 20, 2024 Vol 19, 2023 Vol 18, 2022 Volume 17, 2021 Vol 16, 2020 Vol 15, 2019 Vol 14, 2018 Vol 13, 2017 Vol 12, 2016 Vol 11, 2015 Vol 10, 2014 Vol 9, 2013 Vol 8, 2012 Vol 7, 2011 Vol 6, 2010 Vol 5, 2009 Vol 4, 2008 Vol 3, 2007 Vol 2, 2006 Vol 1, 2005
Download citations Download PDFs Download issue

Review

Update on drug-drug interaction at organic cation transporters: mechanisms, clinical impact, and proposal for advanced in vitro testing
Hermann Koepsell
Pages: 635-653
Published online: 09 Jun 2021
AbstractforUpdate on drug-drug interaction at organic cation transporters: mechanisms, clinical impact, and proposal for advanced in vitro testing | Full Text | References | PDF (2.7 MB) | EPUB
  • 5306 Views
  • 2 CrossRef citations
  • 0Altmetric
Open Access
Current strategies for predicting side effects from second generation antipsychotics in youth
Jacob T. Brown, Claudia Campo-Soria & Jeffrey R. Bishop
Pages: 655-664
Published online: 02 May 2021
AbstractforCurrent strategies for predicting side effects from second generation antipsychotics in youth | Full Text | References | PDF (370.1 KB) | EPUB
  • 365 Views
  • 0 CrossRef citations
  • 0Altmetric
The impact of age on antiretroviral drug pharmacokinetics in the treatment of adults living with HIV
Andrea Calcagno, Mattia Trunfio, Antonio D’Avolio, Giovanni Di Perri & Stefano Bonora
Pages: 665-676
Published online: 29 Apr 2021
AbstractforThe impact of age on antiretroviral drug pharmacokinetics in the treatment of adults living with HIV | Full Text | References | PDF (2.7 MB) | EPUB
  • 295 Views
  • 0 CrossRef citations
  • 0Altmetric
How close are we to personalized mitotane dosing in the treatment of adrenocortical carcinoma? State of the art and future perspectives
Rebecca V. Steenaard, Madeleine H.T. Ettaieb, Thomas M.A. Kerkhofs & Harm R. Haak
Pages: 677-683
Published online: 04 May 2021
AbstractforHow close are we to personalized mitotane dosing in the treatment of adrenocortical carcinoma? State of the art and future perspectives | Full Text | References | PDF (321.8 KB) | EPUB
  • 200 Views
  • 0 CrossRef citations
  • 0Altmetric
Polymorphisms of genes related to phase-I metabolic enzymes affecting the clinical efficacy and safety of clopidogrel treatment
Abdullah Alkattan & Eman Alsalameen
Pages: 685-695
Published online: 15 May 2021
AbstractforPolymorphisms of genes related to phase-I metabolic enzymes affecting the clinical efficacy and safety of clopidogrel treatment | Full Text | References | PDF (398 KB) | EPUB
  • 317 Views
  • 0 CrossRef citations
  • 0Altmetric
Potential drug-drug interaction between sodium-glucose co-transporter 2 inhibitors and statins: pharmacological and clinical evidence
Panagiotis-Nikolaos Lalagkas, Georgios Poulentzas, Christos Kontogiorgis & Antonios Douros
Pages: 697-705
Published online: 26 May 2021
AbstractforPotential drug-drug interaction between sodium-glucose co-transporter 2 inhibitors and statins: pharmacological and clinical evidence | Full Text | References | PDF (415.4 KB) | EPUB
  • 648 Views
  • 1 CrossRef citations
  • 0Altmetric
Han Chinese specific cytochrome P450 polymorphisms and their impact on the metabolism of anti-hypertensive drugs with adrenoreceptor blocking properties
Jian-Chang Qian, Jian-Ping Cai & Guo-Xin Hu
Pages: 707-716
Published online: 03 May 2021
AbstractforHan Chinese specific cytochrome P450 polymorphisms and their impact on the metabolism of anti-hypertensive drugs with adrenoreceptor blocking properties | Full Text | References | PDF (1.4 MB) | EPUB
  • 169 Views
  • 0 CrossRef citations
  • 0Altmetric

Original Research

Article
Development and evaluation of a physiologically based pharmacokinetic model to predict carvedilol-paroxetine metabolic drug–drug interaction in healthy adults and its extrapolation to virtual chronic heart failure patients for dose optimization
Muhammad Fawad Rasool & Stephanie Läer
Pages: 717-724
Published online: 04 May 2021
AbstractforDevelopment and evaluation of a physiologically based pharmacokinetic model to predict carvedilol-paroxetine metabolic drug–drug interaction in healthy adults and its extrapolation to virtual chronic heart failure patients for dose optimization | Full Text | References | PDF (821.3 KB) | EPUB | Supplemental
  • 290 Views
  • 0 CrossRef citations
  • 0Altmetric
Article
Safety and pharmacokinetic interaction between fotagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin in healthy subjects
Yanhua Ding, Hong Zhang, Cuiyun Li, WenBo Zheng, Meng Wang, Ying Li, HaiGang Sun & Min Wu
Pages: 725-731
Published online: 26 Apr 2021
AbstractforSafety and pharmacokinetic interaction between fotagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin in healthy subjects | Full Text | References | PDF (533.8 KB) | EPUB
  • 182 Views
  • 0 CrossRef citations
  • 0Altmetric

Explore articles

Explore the most recently published articles

Pharmacokinetic evaluation of Donanemab for the treatment of Alzheimer’s
Tanya Song et al.
Review Article | Published online: 17 May 2024
The role of the circadian timing system on drug metabolism and detoxification: an update
Alper Okyar et al.
Review Article | Published online: 16 May 2024
Pharmacokinetic and toxicological considerations affecting antiretroviral drug dosing in pregnant women
Zoran Todorović et al.
Review Article | Published online: 14 May 2024
Recent progress in machine learning approaches for predicting carcinogenicity in drug development
Nguyen Quoc Khanh Le et al.
Review Article | Published online: 14 May 2024
View all latest articles