Expert Opinion on Therapeutic Targets, Volume 14, Issue 5 (2010)

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Expert Opinion on Therapeutic Targets, Volume 14, Issue 5 (2010)

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Original Research

Article
The lysosome among targets of metformin: new anti-inflammatory uses for an old drug?
Thomas D Lockwood
Pages: 467-478
Published online: 14 Apr 2010
AbstractforThe lysosome among targets of metformin: new anti-inflammatory uses for an old drug? | Full Text | References | PDF (469.6 KB)
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Perspective

Article
Therapeutic potential of IL-27 in systemic lupus erythematosus
Hai-Feng Pan, Jin-Hui Tao & Dong-Qing Ye
Pages: 479-484
Published online: 29 Mar 2010
AbstractforTherapeutic potential of IL-27 in systemic lupus erythematosus | Full Text | References | PDF (221.9 KB)
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Reviews

Article
New pathways of the renin–angiotensin system: the role of ACE2 in cardiovascular pathophysiology and therapy
Paulo Castro-Chaves, Rui Cerqueira, Mariana Pintalhao & Adelino F Leite-Moreira
Pages: 485-496
Published online: 14 Apr 2010
AbstractforNew pathways of the renin–angiotensin system: the role of ACE2 in cardiovascular pathophysiology and therapy | Full Text | References | PDF (362.5 KB)
  • 625 Views
  • 23 CrossRef citations
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Article
Targeting mitochondrial dysfunction in neurodegenerative disease: Part II
Victoria S Burchell BA, Sonia Gandhi PhD MRCP, Emma Deas PhD, Nicholas W Wood PhD FRCP, Andrey Y Abramov PhD & Hélène Plun-Favreau PhD
Pages: 497-511
Published online: 24 Mar 2010
AbstractforTargeting mitochondrial dysfunction in neurodegenerative disease: Part II | Full Text | References | PDF (476.8 KB)
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Article
Targeting TRPC6 channels in oesophageal carcinoma growth
Xia Ding, Zhuohao He, Yu Shi, Qun Wang & Yizheng Wang
Pages: 513-527
Published online: 17 Mar 2010
AbstractforTargeting TRPC6 channels in oesophageal carcinoma growth | Full Text | References | PDF (416.1 KB)
  • 305 Views
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Article
Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials
Thomas H Beckham, Saeed Elojeimy MD PhD, Joseph C Cheng, Lorianne S Turner PhD, Stanley R Hoffman PhD, James S Norris PhD & Xiang Liu MD PhD
Pages: 529-539
Published online: 24 Mar 2010
AbstractforTargeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials | Full Text | References | PDF (215.9 KB)
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Article
Targeting Notch signaling in pancreatic cancer
Elodie Ristorcelli & Dominique Lombardo
Pages: 541-552
Published online: 14 Apr 2010
AbstractforTargeting Notch signaling in pancreatic cancer | Full Text | References | PDF (397.5 KB)
  • 299 Views
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Article
Targeting the Notch signaling pathway in autoimmune diseases
Daoxin Ma, Yuanchao Zhu, Chunyan Ji & Ming Hou
Pages: 553-565
Published online: 24 Mar 2010
AbstractforTargeting the Notch signaling pathway in autoimmune diseases | Full Text | References | PDF (239 KB)
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Article
Circadian rhythms, adrenergic hormones and trafficking of hematopoietic stem cells
Aldo Giudice, Michele Caraglia, Monica Marra, Maurizio Montella, Nicola Maurea, Alberto Abbruzzese & Claudio Arra
Pages: 567-575
Published online: 29 Mar 2010
AbstractforCircadian rhythms, adrenergic hormones and trafficking of hematopoietic stem cells | Full Text | References | PDF (288.9 KB)
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