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Volume 19, Issue 7

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 7 (2015)

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 7 (2015)

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Vol 28, 2024 Vol 27, 2023 Vol 26, 2022 Vol 25, 2021 Vol 24, 2020 Vol 23, 2019 Vol 22, 2018 Vol 21, 2017 Vol 20, 2016 Volume 19, 2015 Vol 18, 2014 Vol 17, 2013 Vol 16, 2012 Vol 15, 2011 Vol 14, 2010 Vol 13, 2009 Vol 12, 2008 Vol 11, 2007 Vol 10, 2006 Vol 9, 2005 Vol 8, 2004 Vol 7, 2003 Vol 6, 2002 Vol 5, 2001 Vol 5, 2001 Vol 4, 2000 Vol 3, 1999 Vol 2, 1998 Vol 1, 1997

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Editorial

Is there potential to target FOXM1 for ‘undruggable’ lung cancers?

Vladimir V Kalinichenko & Tanya V Kalin

Pages: 865-867

Published online: 04 May 2015

AbstractforIs there potential to target FOXM1 for ‘undruggable’ lung cancers? | Full Text | References | PDF (129.5 KB)

1929 Views
14 CrossRef citations
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Free Access

Review

Novel therapeutic targets of metformin: metabolic syndrome and cardiovascular disease

Ricardo Ladeiras-Lopes MD, Ricardo Fontes-Carvalho MD, Nuno Bettencourt MD PhD, Francisco Sampaio MD PhD, Vasco Gama MD & Adelino Leite-Moreira MD PhD

Pages: 869-877

Published online: 11 Mar 2015

AbstractforNovel therapeutic targets of metformin: metabolic syndrome and cardiovascular disease | Full Text | References | PDF (434.7 KB)

904 Views
28 CrossRef citations
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Non-NMDAR neuronal Ca²⁺–permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage

Chaokun Li, Li Meng, Xin Li, Dongliang Li & Lin-Hua Jiang

Pages: 879-892

Published online: 02 Mar 2015

AbstractforNon-NMDAR neuronal Ca²⁺–permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage | Full Text | References | PDF (430.9 KB)

334 Views
20 CrossRef citations
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Leptin signaling as a therapeutic target of obesity

Neira Sáinz, Carlos J González-Navarro, J Alfredo Martínez & Maria J Moreno-Aliaga

Pages: 893-909

Published online: 01 Mar 2015

AbstractforLeptin signaling as a therapeutic target of obesity | Full Text | References | PDF (475.5 KB)

764 Views
23 CrossRef citations
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Are big potassium-type Ca²⁺-activated potassium channels a viable target for the treatment of epilepsy?

Antonio Leo, Rita Citraro, Andrew Constanti, Giovambattista De Sarro (Professor, Chair of Pharmacology) MD & Emilio Russo

Pages: 911-926

Published online: 03 Apr 2015

AbstractforAre big potassium-type Ca²⁺-activated potassium channels a viable target for the treatment of epilepsy? | Full Text | References | PDF (433.8 KB)

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Homocysteine as a potential biomarker in bipolar disorders: a critical review and suggestions for improved studies

Ahmad Ghanizadeh (Psychiatrist) MD, Ajeet B Singh MBBS MPsych MD FRANZCP, Michael Berk (Psychiatrist) MBBCh MMed (Psych) FF(Psych)SA PhD FRANZCP & Mohammad Torabi-Nami MD PhD

Pages: 927-939

Published online: 16 Apr 2015

AbstractforHomocysteine as a potential biomarker in bipolar disorders: a critical review and suggestions for improved studies | Full Text | References | PDF (312.5 KB)

322 Views
18 CrossRef citations
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Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy

Mahdi Shabani PhD, Jila Naseri MD & Fazel Shokri PhD

Pages: 941-955

Published online: 02 Apr 2015

AbstractforReceptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy | Full Text | References | PDF (504.7 KB)

1321 Views
31 CrossRef citations
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The centrosome: a prospective entrant in cancer therapy

Jubina B Venghateri, Bhavya Jindal & Dulal Panda

Pages: 957-972

Published online: 18 Mar 2015

AbstractforThe centrosome: a prospective entrant in cancer therapy | Full Text | References | PDF (782.8 KB)

393 Views
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Novel therapeutic targets and predictive markers for hepatocellular carcinoma

Stephen L Chan, Anthony WH Chan & Winnie Yeo

Pages: 973-983

Published online: 24 Apr 2015

AbstractforNovel therapeutic targets and predictive markers for hepatocellular carcinoma | Full Text | References | PDF (516.8 KB)

489 Views
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Original Research

Article

Decrease of phosphorylated proto-oncogene CREB at Ser 133 site inhibits growth and metastatic activity of renal cell cancer

Xue Wang, Yu Ren, Haihui Zhuang, Xiangyu Meng, Shuaishuai Huang, Yanyuan Li, Michael Hehir & Ping Wang

Pages: 985-995

Published online: 03 Jun 2015

AbstractforDecrease of phosphorylated proto-oncogene CREB at Ser 133 site inhibits growth and metastatic activity of renal cell cancer | Full Text | References | PDF (931.9 KB)

259 Views
15 CrossRef citations
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Article

Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD₂ pathway

Pengyun Li, Xingmin Wang, Ming Zhao MD, Rui Song MD PhD & Ke-seng Zhao

Pages: 997-1010

Published online: 15 Jun 2015

AbstractforPolydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD₂ pathway | Full Text | References | PDF (1.3 MB) | Supplemental

275 Views
42 CrossRef citations
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