Leukemia & Lymphoma, Volume 58, Issue 6 (2017)

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Leukemia & Lymphoma, Volume 58, Issue 6 (2017)

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Commentaries

Choosing a hypomethylating agent in MDS: does gender matter?
Matthieu Duchmann & Raphael Itzykson
Pages: 1277-1278
Published online: 31 Jan 2017
CitationforChoosing a hypomethylating agent in MDS: does gender matter? | Full Text | References | PDF (238.5 KB) | Supplemental
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Second allogeneic transplantation: ever? never? or sometimes
Sebastian Mayer & Koen van Besien
Pages: 1279-1280
Published online: 14 Nov 2016
CitationforSecond allogeneic transplantation: ever? never? or sometimes | Full Text | References | PDF (238.9 KB) | Supplemental
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Microvesicles in chronic lymphocytic leukemia: ready for prime time in the clinic?
Sasanka M. Handunnetti, Aaron Polliack & Constantine S. Tam
Pages: 1281-1282
Published online: 08 Mar 2017
CitationforMicrovesicles in chronic lymphocytic leukemia: ready for prime time in the clinic? | Full Text | References | PDF (228.2 KB) | Supplemental
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Reviews

High-risk multiple myeloma: a multifaceted entity, multiple therapeutic challenges
Eli Muchtar, Hila Magen & Morie A. Gertz
Pages: 1283-1296
Published online: 13 Oct 2016
AbstractforHigh-risk multiple myeloma: a multifaceted entity, multiple therapeutic challenges | Full Text | References | PDF (1.3 MB) | Supplemental
  • 793 Views
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miRNAs in chronic myeloid leukemia: small molecules, essential function
Zofia Litwińska & Bogusław Machaliński
Pages: 1297-1305
Published online: 13 Oct 2016
AbstractformiRNAs in chronic myeloid leukemia: small molecules, essential function | Full Text | References | PDF (712.1 KB) | Supplemental
  • 594 Views
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Targeting histone deacetylases in T-cell lymphoma
Alison J. Moskowitz & Steven M. Horwitz
Pages: 1306-1319
Published online: 04 Nov 2016
AbstractforTargeting histone deacetylases in T-cell lymphoma | Full Text | References | PDF (1.1 MB) | Supplemental
  • 5390 Views
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Open Access

Clinical Dilemma

Novel agents versus chemotherapy as frontline treatment of CLL
Anna Piggin, Emma Bayly & Constantine S. Tam
Pages: 1320-1324
Published online: 06 Feb 2017
AbstractforNovel agents versus chemotherapy as frontline treatment of CLL | Full Text | References | PDF (425.6 KB) | Supplemental
  • 550 Views
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Original Articles: Clinical

Differential response to hypomethylating agents based on sex: a report on behalf of the MDS Clinical Research Consortium (MDS CRC)*
Amy E. DeZern, Amer M. Zeidan, John Barnard, Wesley Hand, Najla Al Ali, Francis Brown, Cassie Zimmerman, Gail J. Roboz, Guillermo Garcia-Manero, David P. Steensma, Rami S. Komrokji, Mikkael A. Sekeres & on behalf of the Evans MDS Clinical Research Consortium
Pages: 1325-1331
Published online: 24 Oct 2016
AbstractforDifferential response to hypomethylating agents based on sex: a report on behalf of the MDS Clinical Research Consortium (MDS CRC)* | Full Text | References | PDF (585.7 KB) | Supplemental
  • 449 Views
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Investigator and independent review committee exploratory assessment and verification of tumor response in a non-Hodgkin lymphoma study
Robert R. Ford, Robert W. Ford, Michael O’Neal, Brad S. Kahl, Ling Chen, Mihaela Munteanu & Bruce D. Cheson
Pages: 1332-1340
Published online: 10 Oct 2016
AbstractforInvestigator and independent review committee exploratory assessment and verification of tumor response in a non-Hodgkin lymphoma study | Full Text | References | PDF (730.9 KB) | Supplemental
  • 7826 Views
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Open Access
Value of interim FDG PET/CT for predicting outcome of patients with angioimmunoblastic T-cell lymphoma
Seung Hwan Moon, Ah Young Lee, Won-Seog Kim, Seok Jin Kim, Young Seok Cho, Yearn Seong Choe, Byung-Tae Kim & Kyung-Han Lee
Pages: 1341-1348
Published online: 09 Oct 2016
AbstractforValue of interim FDG PET/CT for predicting outcome of patients with angioimmunoblastic T-cell lymphoma | Full Text | References | PDF (820.4 KB) | Supplemental
  • 285 Views
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A phase 1 study of bortezomib and romidepsin in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma, indolent B-cell lymphoma, peripheral T-cell lymphoma, or cutaneous T-cell lymphoma
Beata Holkova, Victor Yazbeck, Maciej Kmieciak, Prithviraj Bose, Shuo Ma, Amy Kimball, Mary Beth Tombes, Ellen Shrader, Wen Wan, Caryn Weir-Wiggins, Amanda Singh, Kevin T. Hogan, Sarah Conine, Heidi Sankala, John D. Roberts, Thomas C. Shea & Steven Grant
Pages: 1349-1357
Published online: 19 Jan 2017
AbstractforA phase 1 study of bortezomib and romidepsin in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma, indolent B-cell lymphoma, peripheral T-cell lymphoma, or cutaneous T-cell lymphoma | Full Text | References | PDF (948.1 KB) | Supplemental
  • 464 Views
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The CDK inhibitor AT7519M in patients with relapsed or refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. A Phase II study of the Canadian Cancer Trials Group
Matthew D. Seftel, John Kuruvilla, Tom Kouroukis, Versha Banerji, Graeme Fraser, Michael Crump, Rajat Kumar, Haji I. Chalchal, Muhammad Salim, Rob C. Laister, Susan Crocker, Spencer B. Gibson, Marcia Toguchi, John F. Lyons, Hao Xu, Jean Powers, Joana Sederias, Lesley Seymour & Annette E. Hay
Pages: 1358-1365
Published online: 17 Oct 2016
AbstractforThe CDK inhibitor AT7519M in patients with relapsed or refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. A Phase II study of the Canadian Cancer Trials Group | Full Text | References | PDF (683.6 KB) | Supplemental
  • 533 Views
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Article
Relapsed chronic lymphocytic leukemia retreated with rituximab: interim results of the PERLE study
Driss Chaoui, Sylvain Choquet, Laurence Sanhes, Béatrice Mahé, Maya Hacini, Olivier Fitoussi, Yazid Arkam, Hubert Orfeuvre, Marie-Sarah Dilhuydy, Marly Barry, Eric Jourdan, Brigitte Dreyfus, Adrian Tempescul, Stéphane Leprêtre, Aurélie Bardet, Pierre Leconte, Marc Maynadié & Alain Delmer
Pages: 1366-1375
Published online: 09 Feb 2017
AbstractforRelapsed chronic lymphocytic leukemia retreated with rituximab: interim results of the PERLE study | Full Text | References | PDF (1 MB) | Supplemental
  • 275 Views
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Pharmacovigilance during ibrutinib therapy for chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) in routine clinical practice
Heidi D. Finnes, Kari G. Chaffee, Timothy G. Call, Wei Ding, Saad S. Kenderian, Deborah A. Bowen, Michael Conte, Kristen B. McCullough, Julianna A. Merten, Gabriel T. Bartoo, Matthew D. Smith, Jose Leis, Asher Chanan-Khan, Susan M. Schwager, Susan L. Slager, Neil E. Kay, Tait D. Shanafelt & Sameer A. Parikh
Pages: 1376-1383
Published online: 08 Nov 2016
AbstractforPharmacovigilance during ibrutinib therapy for chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) in routine clinical practice | Full Text | References | PDF (746 KB) | Supplemental
  • 730 Views
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Concordant optimal molecular and cytogenetic responses at both 3 and 6 months predict a higher probability of MR4.5 achievement in patients with chronic myeloid leukemia treated with imatinib
Ya-Zhen Qin, Qian Jiang, Yue-Yun Lai, Hao Jiang, Hong-Xia Shi, Xiao-Su Zhao, Yan-Rong Liu & Xiao-Jun Huang
Pages: 1384-1393
Published online: 12 Oct 2016
AbstractforConcordant optimal molecular and cytogenetic responses at both 3 and 6 months predict a higher probability of MR4.5 achievement in patients with chronic myeloid leukemia treated with imatinib | Full Text | References | PDF (1.2 MB) | Supplemental
  • 169 Views
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Clinical significance of galectin-3 in patients with adult acute myeloid leukemia: a retrospective cohort study with long-term follow-up and formulation of risk scoring system
Na Gao, Wen-Zheng Yu, Nong-Jian Guo, Xue-Xia Wang & Jian-Rong Sun
Pages: 1394-1402
Published online: 13 Oct 2016
AbstractforClinical significance of galectin-3 in patients with adult acute myeloid leukemia: a retrospective cohort study with long-term follow-up and formulation of risk scoring system | Full Text | References | PDF (1.2 MB) | Supplemental
  • 240 Views
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Outcome and prognostic factors among patients who underwent a second transplantation for disease relapse post the first allogeneic cell transplantation
Takayoshi Tachibana, Kenji Matsumoto, Masatsugu Tanaka, Maki Hagihara, Kenji Motohashi, Wataru Yamamoto, Eriko Ogusa, Satoshi Koyama, Ayumi Numata, Naoto Tomita, Jun Taguchi, Shin Fujisawa, Heiwa Kanamori & Hideaki Nakajima
Pages: 1403-1411
Published online: 14 Oct 2016
AbstractforOutcome and prognostic factors among patients who underwent a second transplantation for disease relapse post the first allogeneic cell transplantation | Full Text | References | PDF (840 KB) | Supplemental
  • 224 Views
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Incidence rates of treatment-emergent adverse events and related hospitalization are reduced with azacitidine compared with conventional care regimens in older patients with acute myeloid leukemia
John F. Seymour, Hartmut Döhner, Mark D. Minden, Richard Stone, Dominique Gambini, Donna Dougherty, C.L. Beach, Jerry Weaver & Hervé Dombret
Pages: 1412-1423
Published online: 14 Oct 2016
AbstractforIncidence rates of treatment-emergent adverse events and related hospitalization are reduced with azacitidine compared with conventional care regimens in older patients with acute myeloid leukemia | Full Text | References | PDF (2.1 MB) | Supplemental
  • 575 Views
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Original Articles: Research

Characterization and prognostic relevance of circulating microvesicles in chronic lymphocytic leukemia
Luciana De Luca, Giovanni D’Arena, Vittorio Simeon, Stefania Trino, Ilaria Laurenzana, Antonella Caivano, Francesco La Rocca, Oreste Villani, Giovanna Mansueto, Silvia Deaglio, Idanna Innocenti, Luca Laurenti, Stefano Molica, Giuseppe Pietrantuono, Angelo De Stradis, Luigi Del Vecchio & Pellegrino Musto
Pages: 1424-1432
Published online: 14 Oct 2016
AbstractforCharacterization and prognostic relevance of circulating microvesicles in chronic lymphocytic leukemia | Full Text | References | PDF (1.1 MB) | Supplemental
  • 516 Views
  • 39 CrossRef citations
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Iron chelation: an adjuvant therapy to target metabolism, growth and survival of murine PTEN-deficient T lymphoma and human T lymphoblastic leukemia/lymphoma
Joy Benadiba, Celia Rosilio, Marielle Nebout, Vera Heimeroth, Zouhour Neffati, Alexandra Popa, Didier Mary, Emmanuel Griessinger, Véronique Imbert, Nicolas Sirvent & Jean-François Peyron
Pages: 1433-1445
Published online: 13 Oct 2016
AbstractforIron chelation: an adjuvant therapy to target metabolism, growth and survival of murine PTEN-deficient T lymphoma and human T lymphoblastic leukemia/lymphoma | Full Text | References | PDF (2.1 MB) | Supplemental
  • 408 Views
  • 18 CrossRef citations
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Hematopoietic stem cells can be separated from leukemic cells in a subgroup of adult acute lymphoblastic leukemia patients
Wenwen Wang, Elena Foerner, Eike Buss, Anna Jauch, Volker Eckstein, Patrick Wuchter, Anthony D. Ho & Christoph Lutz
Pages: 1446-1454
Published online: 13 Oct 2016
AbstractforHematopoietic stem cells can be separated from leukemic cells in a subgroup of adult acute lymphoblastic leukemia patients | Full Text | References | PDF (1.6 MB) | Supplemental
  • 229 Views
  • 1 CrossRef citations
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Ponatinib reduces viability, migration, and functionality of human endothelial cells
Ayala Gover-Proaktor, Galit Granot, Saar Shapira, Oshrat Raz, Oren Pasvolsky, Arnon Nagler, Dorit L. Lev, Aida Inbal, Ido Lubin, Pia Raanani & Avi Leader
Pages: 1455-1467
Published online: 12 Oct 2016
AbstractforPonatinib reduces viability, migration, and functionality of human endothelial cells | Full Text | References | PDF (2.1 MB) | Supplemental
  • 707 Views
  • 35 CrossRef citations
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Nuclear ERK5 inhibits progression of leukemic monocytes to macrophages by regulating the transcription factor PU.1 and heat shock protein HSP70
Ruifang Zheng & George P. Studzinski
Pages: 1468-1480
Published online: 17 Oct 2016
AbstractforNuclear ERK5 inhibits progression of leukemic monocytes to macrophages by regulating the transcription factor PU.1 and heat shock protein HSP70 | Full Text | References | PDF (3.3 MB) | Supplemental
  • 157 Views
  • 1 CrossRef citations
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The potential role of hematocrit control on symptom burden among polycythemia vera patients: Insights from the CYTO-PV and MPN-SAF patient cohorts
Robyn Marie Scherber, Holly Lynn Geyer, Amylou C. Dueck, Heidi E. Kosiorek, Guido Finazzi, Riccardo Cavazzina, Arianna Masciulli, Marco Scarano, Alessandro M. Vannucchi, Ruben A. Mesa & Tiziano Barbui
Pages: 1481-1487
Published online: 10 Nov 2016
AbstractforThe potential role of hematocrit control on symptom burden among polycythemia vera patients: Insights from the CYTO-PV and MPN-SAF patient cohorts | Full Text | References | PDF (963.9 KB) | Supplemental
  • 508 Views
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Letters to the Editor

Spectrum of autoimmune diseases and systemic inflammatory syndromes in patients with chronic myelomonocytic leukemia
Mohammad Faizan Zahid, Daniela Barraco, Terra L. Lasho, Christy Finke, Rhett P. Ketterling, Naseema Gangat, Curtis A. Hanson, Ayalew Tefferi & Mrinal M. Patnaik
Pages: 1488-1493
Published online: 14 Oct 2016
First Page PreviewforSpectrum of autoimmune diseases and systemic inflammatory syndromes in patients with chronic myelomonocytic leukemia | Full Text | References | PDF (481.5 KB) | Supplemental
  • 746 Views
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Rethinking the role of osteopontin in human acute myeloid leukemia
Annette K. Brenner, Elise Aasebø, Maria Hernandez-Valladares, Frode Selheim, Frode Berven & Øystein Bruserud
Pages: 1494-1497
Published online: 14 Oct 2016
First Page PreviewforRethinking the role of osteopontin in human acute myeloid leukemia | Full Text | References | PDF (534.9 KB) | Supplemental
  • 278 Views
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MLL-rearranged mixed phenotype acute leukemia masquerading as B-cell ALL
Wei Yang, Phu Tran, Ziad Khan, Sherif Rezk & Susan O’Brien
Pages: 1498-1501
Published online: 24 Oct 2016
First Page PreviewforMLL-rearranged mixed phenotype acute leukemia masquerading as B-cell ALL | Full Text | References | PDF (1.1 MB) | Supplemental
  • 203 Views
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Extended follow-up with the Bruton’s tyrosine kinase inhibitor ibrutinib in previously treated Waldenström’s macroglobulinemia
Richard R. Furman, Ying Luan, Elizabeth Bilotti & Thorsten Graef
Pages: 1502-1505
Published online: 26 Oct 2016
First Page PreviewforExtended follow-up with the Bruton’s tyrosine kinase inhibitor ibrutinib in previously treated Waldenström’s macroglobulinemia | Full Text | References | PDF (733.2 KB) | Supplemental
  • 338 Views
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Phase 2 study of ofatumumab, fludarabine and cyclophosphamide in relapsed/refractory Waldenström’s macroglobulinemia
Maria Gavriatopoulou, Efstathios Kastritis, Marie-Christine Kyrtsonis, Theodoros P. Vassilakopoulos, Maria Roussou, Despoina Fotiou, Magdalini Migkou, Maria Mpakiri, Anna Tasidou, Evangelos Terpos & Meletios Athanasios Dimopoulos
Pages: 1506-1508
Published online: 10 Oct 2016
First Page PreviewforPhase 2 study of ofatumumab, fludarabine and cyclophosphamide in relapsed/refractory Waldenström’s macroglobulinemia | Full Text | References | PDF (452.3 KB) | Supplemental
  • 200 Views
  • 9 CrossRef citations
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Clinicopathological characteristics of malignant lymphoma in patients with hepatitis C virus infection in the Tohoku district in Eastern Japan
Katsushi Tajima, Naoto Takahashi, Kenichi Ishizawa, Kazunori Murai, Tomoaki Akagi, Hideyoshi Noji, Osamu Sasaki, Masaharu Wano, Jugoh Itoh, Yuichi Kato, Tsutomu Shichishima, Hideo Harigae, Yoji Ishida & for the Tohoku Hematology Forum
Pages: 1509-1511
Published online: 10 Oct 2016
First Page PreviewforClinicopathological characteristics of malignant lymphoma in patients with hepatitis C virus infection in the Tohoku district in Eastern Japan | Full Text | References | PDF (349.5 KB) | Supplemental
  • 82 Views
  • 3 CrossRef citations
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Haplo-cord transplant: HLA-matching determines graft dominance
Koen van Besien, Nebu Koshy, Usama Gergis, Sebastian Mayer, Melissa Cushing, Hannah Rennert, Ronit Reich-Slotky, Tomer Mark, Roger Pearse, Adriana Rossi, Adrienne Phillips, Liljana Vasovic, Rosanna Ferrante, Yen-Michael Hsu & Tsiporah Shore
Pages: 1512-1514
Published online: 27 Oct 2016
First Page PreviewforHaplo-cord transplant: HLA-matching determines graft dominance | Full Text | References | PDF (406.5 KB) | Supplemental
  • 234 Views
  • 8 CrossRef citations
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Anaplastic mast cell sarcoma: a unique pathologic entity in mastocytosis
Fiona He, Hans-Peter Horny, Jamie Boone, Ahmad Raza, Megan Griffith, Peter Hurley, Michelle Dolan, Zuzan Cayci, Michael A. Linden, Robert McKenna & Celalettin Ustun
Pages: 1515-1517
Published online: 03 Nov 2016
First Page PreviewforAnaplastic mast cell sarcoma: a unique pathologic entity in mastocytosis | Full Text | References | PDF (912.2 KB) | Supplemental
  • 289 Views
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Correspondence

CML with pregnancy: real challenges in developing nations
Kamal Kant Sahu, Deba Prasad Dhibar, Subhash Varma & Pankaj Malhotra
Pages: 1518-1519
Published online: 16 Nov 2016
CitationforCML with pregnancy: real challenges in developing nations | Full Text | References | PDF (225.6 KB) | Supplemental
  • 166 Views
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