Views

CrossRef citations to date

Altmetric

Reviews

Advances in physiological functions and mechanisms of (−)-epicatechin

Zhihao QuKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, China; ;National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan, China; View further author information

Ailing LiuCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, Hunan, ChinaView further author information

Penghui LiKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, China; ;National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan, China;

http://orcid.org/0000-0003-0662-6621 View further author information

Changwei LiuKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, China; ;National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan, China; View further author information

Wenjun XiaoKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, China; ;National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan, China; View further author information

Jianan HuangKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, China; ;National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan, China; View further author information

Zhonghua LiuKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, China; ;National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan, China; Correspondence[email protected]

http://orcid.org/0000-0003-4645-7092 View further author information

Sheng ZhangKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, China; ;National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Collaborative Innovation Centre of Utilisation of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan, China; Correspondence[email protected]

http://orcid.org/0000-0003-2288-1120 View further author information

show all

Abstract

(−)-Epicatechin (EC) is a flavanol easily obtained through the diet and is present in tea, cocoa, vegetables, fruits, and cereals. Recent studies have shown that EC protects human health and exhibits prominent anti-oxidant and anti-inflammatory activities, enhances muscle performance, improves symptoms of cardiovascular and cerebrovascular diseases, prevents diabetes, and protects the nervous system. With the development of modern medical and biotechnology research, the mechanisms of action associated with EC toward various chronic diseases are becoming more apparent, and the pharmacological development and utilization of EC has been increasingly clarified. Currently, there is no comprehensive systematic introduction to the effects of EC and its mechanisms of action. This review presents the latest research progress and the role of EC in the prevention and treatment of various chronic diseases and its protective health effects and provides a theoretical basis for future research on EC.

Keywords:

Conflict of interest

All authors declare that they have no conflicts of interest involving this work.

Additional information

Funding

This work was supported in part by the Natural Science Foundation of Hunan Province (2019JJ40120), the National Key R&D Project (2017YFD0400803), and the Changsha Science and Technology Major Project (kq1703003).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Advances in physiological functions and mechanisms of (−)-epicatechin

Information for

Open access

Opportunities

Help and information

Advances in physiological functions and mechanisms of (−)-epicatechin

Abstract

Conflict of interest

Additional information

Funding

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature