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ABSTRACT
In this study, the biodegradable and biocompatible gelatin-based film containing natamycin was crosslinked by transglutaminase (TGase). The profiles of micro structure, secondary structure, physical properties, and antifungal activities were evaluated. The results of electron microscope and Fourier transform infrared spectroscopy (FTIR) indicated that the structures of films were significantly changed. In addition, the environment for microbial growth and the mechanical properties were evaluated with different concentrations of TGase. Moreover, the films could inhibit the growth of fungus based on microbiological assays. The findings in this paper would facilitate the production of gelatin-based fungistatic composite films.
Funding
This work was supported by the Foundation of National 863 Plan (grant numbers 2013AA102204) and Ministry of Agriculture of China (grant numbers 201303082-3).