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Research Article

Clinical improvement, toxicity and future prospects of β-sitosterol: a review

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Article: 2337886 | Received 11 Dec 2023, Accepted 27 Mar 2024, Published online: 17 Apr 2024
 

ABSTRACT

β-sitosterol is waxy substance, white in color distributed in a variety of natural plant sources cereals, pulses, legumes, vegetables, fruits, and herbs. Several clinical and preclinical investigations indicate that β-sitosterol has a wide range of important health advantages. It prevents many types of malignancies, lowers levels of low density lipoprotein (LDL), lowers the risk of coronary artery disease, heart attacks, and atherosclerosis, and supports the body’s natural healing process. It is found to have cancer-protective properties and has the potency to be beneficial against breast, prostate, colon, lung, stomach, and leukemia. The present review provides a complete analysis and examines the literature on β-sitosterol from different dietary sources, with a focus on its toxicological characteristics and nutraceutical qualities. It lays down the theoretical basis and justification for directing the future planning and execution of clinical studies intended to confirm the importance and possible toxicity of β-sitosterol.

Acknowledgments

The authors are gratefully thanking the University of Lahore for their support.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Consent for publication

All authors agree to publish.

Data availability statement

The authors confirm that the data supporting the findings of this study are available within the article.

Authors contributions

Azka Khan Durrani contribute for the conception of the paper.

Momina Khalid layout the design of paper.

Awais Raza critically analysis the data.

Izza Faiz ul Rasool done the interpretation of the data.

Waseem Khalid drafting the paper.

Muhammad Nadeem Akhtar revising the paper critically for intellectual content.

Ammar Ahmad Khan also revising the paper critically for intellectual content.

Zunair Abdullah also revising the paper critically for intellectual content.

Babirye Khadijah prepare the final draft of paper and after analysis done the final approval before submission.

Additional information

Funding

There are no funding for this paper.