2,084
Views
58
CrossRef citations to date
0
Altmetric
Original Articles

Fiber2 and hexon genes are closely associated with the virulence of the emerging and highly pathogenic fowl adenovirus 4

, , , , , , , , & ORCID Icon show all
Pages 1-10 | Received 05 Jun 2018, Accepted 11 Nov 2018, Published online: 05 Dec 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Fan Gao, Pei Liu, Yaqian Huo, Lianlian Bian, Xing Wu, Mingchen Liu, Qian Wang, Qian He, Fangyu Dong, Zejun Wang, Zhongping Xie, Zhongyang Zhang, Meirong Gu, Yingzhi Xu, Yajing Li, Rui Zhu, Tong Cheng, Tao Wang, Qunying Mao & Zhenglun Liang. (2024) A screening study on the detection strain of Coxsackievirus A6: the key to evaluating neutralizing antibodies in vaccines. Emerging Microbes & Infections 13:1.
Read now
Qian Zhou, Yaqian Cui, Chenxiao Wang, Hanwen Wu, Haifeng Xiong, Kezong Qi & Hongmei Liu. (2024) Characterization of natural co-infection with goose astrovirus genotypes I and II in gout affected goslings. Avian Pathology 53:2, pages 146-153.
Read now
Siddharth C Umarje & Sanjiban K Banerjee. (2023) Non-traditional approaches for control of antibiotic resistance. Expert Opinion on Biological Therapy 23:11, pages 1113-1135.
Read now
Qingdong Luan, Yijun Han, Yanbo Yin & Jianlin Wang. (2022) Genetic diversity and pathogenicity of novel chicken astrovirus in China. Avian Pathology 51:5, pages 488-498.
Read now
Quan Xie, Weikang Wang, Luyuan Li, Qiuqi Kan, Hui Fu, Tuoyu Geng, Tuofan Li, Zhimin Wan, Wei Gao, Hongxia Shao, Aijian Qin & Jianqiang Ye. (2021) Domain in Fiber-2 interacted with KPNA3/4 significantly affects the replication and pathogenicity of the highly pathogenic FAdV-4. Virulence 12:1, pages 754-765.
Read now
Anna Schachner, Beatrice Grafl & Michael Hess. (2021) Spotlight on avian pathology: fowl adenovirus (FAdV) in chickens and beyond – an unresolved host-pathogen interplay. Avian Pathology 50:1, pages 2-5.
Read now
Qing Pan, Jing Wang, Yulong Gao, Qi Wang, Hongyu Cui, Changjun Liu, Xiaole Qi, Yanping Zhang, Yongqiang Wang, Kai Li, Li Gao, Aijing Liu & Xiaomei Wang. (2020) Identification of chicken CAR homology as a cellular receptor for the emerging highly pathogenic fowl adenovirus 4 via unique binding mechanism. Emerging Microbes & Infections 9:1, pages 586-596.
Read now

Articles from other publishers (51)

Chidozie C. Ugwu, Mohd Hair-Bejo, Mat I. Nurulfiza, Abdul R. Omar & Aini Ideris. (2024) Attenuation and molecular characterization of fowl adenovirus 8b propagated in a bioreactor and its immunogenicity, efficacy, and virus shedding in broiler chickens. Veterinary World, pages 744-755.
Crossref
Xiaolan Hou, Lizhen Wang, Riteng Zhang, Gen Liu, Ting Wang, Bo Wen, Wenchi Chang, Shuizhong Han, Jinjie Han, Junyang Fang, Xuefeng Qi & Jingyu Wang. (2024) Differential innate immune responses to fowl adenovirus serotype 4 infection in Leghorn male hepatocellular and chicken embryo fibroblast cells. Poultry Science, pages 103741.
Crossref
Zhaorong Yu, Daoming Shi, Yanli Dong, Ying Shao, Zhe Chen, Fanyu Cheng, Yu Zhang, Zhenyu Wang, Jian Tu & Xiangjun Song. (2024) Pyrococcus furiosus Argonaute combined with loop-mediated isothermal amplification for rapid, ultrasensitive, and visual detection of fowl adenovirus serotype 4. Poultry Science, pages 103729.
Crossref
Wenjian Liu, Meng Liu, Shuaiwen Wang, Zhihui Tang, Jiwen Liu, Suquan Song & Liping Yan. (2024) The Development of a Novel Fiber-2 Subunit Vaccine against Fowl Adenovirus Serotype 4 Formulated with Oil Adjuvants. Vaccines 12:3, pages 263.
Crossref
Shenyan Gao, Ruixue Li, Xiaozhan Zhang & Zeng Wang. (2024) Identification of ORF1B as a unique nonstructural protein for fowl adenovirus serotype 4. Microbial Pathogenesis 186, pages 106508.
Crossref
Yixuan Lu, Yaqin Yuan, Huiru Jiang, Zhenqi Xu, Yiwen Guo, Xudong Cao, Tuofan Li, Zhimin Wan, Hongxia Shao, Aijian Qin, Quan Xie & Jianqiang Ye. (2023) Efficient cross-protection against serotype 4/8a fowl adenoviruses (FAdVs): recombinant FAdV-4 with FAdV-8a Fiber. Microbiology Spectrum 11:6.
Crossref
Ajani Athukorala, Claude Lacasse, Jeffrey B. Curtiss, David N. Phalen & Subir Sarker. (2023) Characterisation of a novel aviadenovirus associated with disease in tawny frogmouths (Podargus strigoides). Virology 588, pages 109904.
Crossref
Jinyu Lai, Liangyu Yang, Fashun Chen, Xingchen He, Rongjie Zhang, Yong Zhao, Gan Gao, Weiwu Mu, Xi Chen, Shiyu Luo, Tao Ren & Bin Xiang. (2023) Prevalence and Molecular Characteristics of FAdV-4 from Indigenous Chicken Breeds in Yunnan Province, Southwestern China. Microorganisms 11:11, pages 2631.
Crossref
Szilvia Jakab, Krisztina Bali, Zalán Homonnay, Eszter Kaszab, Katalin Ihász, Enikő Fehér, Tamás Mató, István Kiss, Vilmos Palya & Krisztián Bányai. (2023) Genomic Epidemiology and Evolution of Fowl Adenovirus 1. Animals 13:18, pages 2819.
Crossref
Shuzhen Chen, Qingdong Luan, Shimei Qiu, Yue Zhao, Yanjin Lu, Shufang Sun, Jianlin Wang & Yanbo Yin. (2023) An efficient and convenient Fiber -2- based latex agglutination test for the detection of antibodies against fowl adenovirus serotype 4 in clinical samples. Journal of Virological Methods 319, pages 114760.
Crossref
Bahiyah Azli, Nur Farhana Salim, Abdul Rahman Omar, Mohd Hair-Bejo, Norfitriah Mohamed Sohaimi & Nurulfiza Mat Isa. (2023) Molecular Characterisation of Partial Structural Genes of Fowl Adenovirus Serotype 8b UPMT1901 Field Strain Isolate Associated with the Inclusion Body Hepatitis in Malaysia’s Commercial Broiler Chickens. Pertanika Journal of Tropical Agricultural Science 46:3, pages 1003-1026.
Crossref
Xiaoyan Xue, Qinhong Yang, Ming J. Wu, Zhenxing Zhang, Jianling Song, Wei Wang, Jia Yang, Jia Ji, Yongxian Zhang, Hongyang Dai, Hongbin Yin & Suhua Li. (2023) Genomic and Pathologic Characterization of the First FAdV-C Serotype 4 Isolate from Black-Necked Crane. Viruses 15:8, pages 1653.
Crossref
Wei Li, Guangju You, Areayi· Haiyilati, Hongnuan Wang, Huixuan Jiao, Yongqiang Wang, Li Gao, Hong Cao, Xiaoqi Li & Shijun J. Zheng. (2023) Critical Role of Viral Protein Hexon in Hypervirulent Fowl Adenovirus Serotype-4-Induced Autophagy by Interaction with BAG3 and Promotion of Viral Replication in LMH Cells. Journal of Virology 97:6.
Crossref
Yiwen Guo, Zhenqi Xu, Yifei Chao, Xudong Cao, Huiru Jiang, Han Li, Tuofan Li, Zhimin Wan, Hongxia Shao, Aijian Qin, Quan Xie & Jianqiang Ye. (2023) An efficient double-fluorescence approach for generating fiber-2-edited recombinant serotype 4 fowl adenovirus expressing foreign gene. Frontiers in Microbiology 14.
Crossref
Xiao Chen, Qiang Wei, Fusheng Si, Fangyu Wang, Qingxia Lu, Zhenhua Guo, Yongxiao Chai, Rongfang Zhu, Guangxu Xing, Qianyue Jin & Gaiping Zhang. (2023) Design and Identification of a Novel Antiviral Affinity Peptide against Fowl Adenovirus Serotype 4 (FAdV-4) by Targeting Fiber2 Protein. Viruses 15:4, pages 821.
Crossref
Ting Wang, Lizhen Wang, Wei Li, Xiaolan Hou, Wenchi Chang, Bo Wen, Shuizhong Han, Yan Chen, Xuefeng Qi & Jingyu Wang. (2023) Fowl adenovirus serotype 4 enters leghorn male hepatocellular cells via the clathrin-mediated endocytosis pathway. Veterinary Research 54:1.
Crossref
Satoko Watanabe, Yu Yamamoto, Aoi Kurokawa, Hiroshi Iseki, Taichiro Tanikawa & Masaji Mase. (2023) Recombinant fiber-1 protein of fowl adenovirus serotype 4 induces high levels of neutralizing antibodies in immunized chickens. Archives of Virology 168:3.
Crossref
Congcong Song, Shiyi Zhao, Mingzhen Song, Qilong Qiao, Panpan Yang, Baiyu Wang, Yanfang Cong, Yanling Wang, Hongying Liu, Zeng Wang, Xinwei Wang & Jun Zhao. (2023) An Inactivated Novel Trivalent Vaccine Provides Complete Protection against FAdV-4 Causing Hepatitis-Hydropericardium Syndrome and FAdV-8b/-11 Causing Inclusion Body Hepatitis. Transboundary and Emerging Diseases 2023, pages 1-13.
Crossref
Zhuozhuang Lu, Yongjin Wang, Xiaohui Zou & Tao Hung. (2023) Analysis of Fowl Adenovirus 4 Transcriptome by De Novo ORF Prediction Based on Corrected Nanopore Full-Length cDNA Sequencing Data. Viruses 15:2, pages 529.
Crossref
Vishranti G. Chavan, Sudhakar P. Awandkar, Mahesh B. Kulkarni, Sambhaji G. Chavhan, Ram C. Kulkarni & Aditya A. Agnihotri. (2022) Molecular phylodynamics of fowl adenovirus serotype 11 and 8b from inclusion body hepatitis outbreaks. Virus Genes 59:1, pages 148-157.
Crossref
Ning Cui, Mei Lu, Shiping Sun, Shouli Sun, Chuantian Xu, Shuai Su, Nataliia Hrabchenko & Qinghua Huang. (2023) Illumina high-throughput sequencing for the genome of emerging fowl adenovirus D species and C species simultaneously. Poultry Science 102:1, pages 102295.
Crossref
Baiyu Wang, Mingzhen Song, Congcong Song, Shiyi Zhao, Panpan Yang, Qilong Qiao, Yanfang Cong, Yanling Wang, Zeng Wang & Jun Zhao. (2022) An inactivated novel chimeric FAdV-4 containing fiber of FAdV-8b provides full protection against hepatitis-hydropericardium syndrome and inclusion body hepatitis. Veterinary Research 53:1.
Crossref
Aijing Liu, Yu Zhang, Jing Wang, Hongyu Cui, Xiaole Qi, Changjun Liu, Yanping Zhang, Kai Li, Li Gao, Xiaomei Wang, Yulong Gao & Qing Pan. (2022) Complete Genome Analysis and Animal Model Development of Fowl Adenovirus 8b. Viruses 14:8, pages 1826.
Crossref
Jie Cao, Shuhui Liu, Meng Liu, Shuaiwen Wang, Zhenwei Bi, Wentao Fan, Zhiyu Shi, Suquan Song & Liping Yan. (2022) Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7. Journal of Virology 96:15.
Crossref
Shenyan Gao, Huayuan Chen, Xiaozhan Zhang, Jun Zhao & Zeng Wang. (2022) Cellular protein HSC70 promotes fowl adenovirus serotype 4 replication in LMH cells via interacting with viral 100K protein. Poultry Science 101:7, pages 101941.
Crossref
Dengyun Niu, Jingjing Feng, Baomin Duan, Qiuying Shi, Ying Li, Zhuo Chen, Lifang Ma, Haixia Liu & Yanxiao Wang. (2022) Epidemiological survey of avian adenovirus in China from 2015 to 2021 and the genetic variability of highly pathogenic Fadv-4 isolates. Infection, Genetics and Evolution 101, pages 105277.
Crossref
Baiyu Wang, Congcong Song, Panpan Yang, Mingzhen Song, Shiyi Zhao, Qilong Qiao, Zeng Wang & Jun Zhao. (2022) The Role of Hexon Amino Acid 188 Varies in Fowl Adenovirus Serotype 4 Strains with Different Virulence. Microbiology Spectrum 10:3.
Crossref
Zhipeng Jia, Xinghui Pan, Wenjing Zhi, Hang Chen, Bingrong Bai, Chunli Ma & Dexing Ma. (2022) Probiotics Surface-Delivering Fiber2 Protein of Fowl Adenovirus 4 Stimulate Protective Immunity Against Hepatitis-Hydropericardium Syndrome in Chickens. Frontiers in Immunology 13.
Crossref
Hassan Zackaria Ali Ishag, Abdelnasir Mohammed Adam Terab, El Tigani Ahmed El Tigani-Asil, Oum Keltoum Bensalah, Nasereldien Altaib Hussein Khalil, Abdelmalik Ibrahim Khalafalla, Zulaikha Mohamed Abdel Hameed Al Hammadi, Asma Abdi Mohamed Shah & Salama Suhail Mohammed Al Muhairi. (2022) Pathology and Molecular Epidemiology of Fowl Adenovirus Serotype 4 Outbreaks in Broiler Chicken in Abu Dhabi Emirate, UAE. Veterinary Sciences 9:4, pages 154.
Crossref
Quan Xie, Weikang Wang, Qiuqi Kan, Yaru Mu, Wei Zhang, Jian Chen, Luyuan Li, Hui Fu, Tuofan Li, Zhimin Wan, Wei Gao, Hongxia Shao, Aijian Qin & Jianqiang Ye. (2022) FAdV-4 without Fiber-2 Is a Highly Attenuated and Protective Vaccine Candidate . Microbiology Spectrum 10:1.
Crossref
Beatrice Grafl, Anna Schachner & Michael Hess. (2022) High Phenotypic Variation between an In Vitro-Passaged Fowl Adenovirus Serotype 1 (FAdV-1) and Its Virulent Progenitor Strain despite Almost Complete Sequence Identity of the Whole Genomes. Viruses 14:2, pages 358.
Crossref
Zhenchao Zhao, Yapeng Song, Zongmei Huang, Lin Liu, Hang Liao, Wenjie Sun, Mingyue Tao, Lijie Li & Xinsheng Li. (2022) Immunity analysis against Fowl Adenovirus serotype 4 (FAdV-4) based on Fiber-2 trimer Protein with the different virulence. Virus Research 308, pages 198652.
Crossref
Ismail Sahindokuyucu, Merve Biskin Turkmen, Tugce Sumer, Ahmed Eisa Elhag, Mehmet Eray Alcigir, Zafer Yazici, Gerald Barry, Mustafa Yavuz Gulbahar & Oguz Kul. (2021) First detection and molecular characterisation of a pigeon aviadenovirus A and pigeon circovirus co‐infection associated with Young Pigeon Disease Syndrome (YPDS) in Turkish pigeons ( Columba livia domestica) . Veterinary Medicine and Science 8:1, pages 139-149.
Crossref
Lili Wang, Li Zheng, Shan Jiang, Xiuli Li, Chao Lu, Li Zhang, Weike Ren, Cheng Li, Xiangxue Tian, Fuqiang Li & Minghua Yan. (2021) Isolation, identification and genetic characterization analysis of a fowl aviadenovirus serotype 4 strain from Tianjin, China. Infection, Genetics and Evolution 96, pages 105078.
Crossref
Yaru Mu, Quan Xie, Weikang Wang, Hao Lu, Mingjun Lian, Wei Gao, Tuofan Li, Zhimin Wan, Hongxia Shao, Aijian Qin & Jianqiang Ye. (2021) A Novel Fiber-1-Edited and Highly Attenuated Recombinant Serotype 4 Fowl Adenovirus Confers Efficient Protection Against Lethal Challenge. Frontiers in Veterinary Science 8.
Crossref
Jixiong Hu, Guopan Li, Xi Wang, Lianshen Cai, Mingxuan Rong, Huan Li, Ming Xie, Zhixiang Zhang & Jun Rong. (2021) Development of a subunit vaccine based on fiber2 and hexon against fowl adenovirus serotype 4. Virus Research 305, pages 198552.
Crossref
Yu Zhang, Aijing Liu, Yanan Wang, Hongyu Cui, Yulong Gao, Xiaole Qi, Changjun Liu, Yanping Zhang, Kai Li, Li Gao, Qing Pan & Xiaomei Wang. (2021) A Single Amino Acid at Residue 188 of the Hexon Protein Is Responsible for the Pathogenicity of the Emerging Novel Virus Fowl Adenovirus 4. Journal of Virology 95:17.
Crossref
Feng Yuan, Huiqi Song, Lei Hou, Li Wei, Shanshan Zhu, Rong Quan, Jing Wang, Dan Wang, Haijun Jiang, Hao Liu & Jue Liu. (2021) Age-dependence of hypervirulent fowl adenovirus type 4 pathogenicity in specific-pathogen-free chickens. Poultry Science 100:8, pages 101238.
Crossref
Lidan Hou, Xiaochun Chen, Jia Wang, Junping Li & Hanchun Yang. (2021) A tandem mass tag-based quantitative proteomic analysis of fowl adenovirus serotype 4-infected LMH cells. Veterinary Microbiology 255, pages 109026.
Crossref
Xiaohui Zou, Yejing Rong, Xiaojuan Guo, Wenzhe Hou, Bingyu Yan, Tao Hung & Zhuozhuang Lu. (2021) Fiber1, but not fiber2, is the essential fiber gene for fowl adenovirus 4 (FAdV-4). Journal of General Virology 102:3.
Crossref
Zhipeng Jia, Chunli Ma, Xuelian Yang, Xinghui Pan, Guangxing Li & Dexing Ma. (2021) Oral Immunization of Recombinant Lactococcus lactis and Enterococcus faecalis Expressing Dendritic Cell Targeting Peptide and Hexon Protein of Fowl Adenovirus 4 Induces Protective Immunity Against Homologous Infection. Frontiers in Veterinary Science 8.
Crossref
Salisu Ahmed, Abdul Razak Mariatulqabtiah, Mohd Hair Bejo, Abdul Rahman Omar, Aini Ideris & Nurulfiza Mat Isa. (2021) Molecular Markers and Phylogenetic Analysis of UPMT27, a Field Isolate of the Malaysian Fowl Adenovirus Associated with Inclusion Body Hepatitis. Pertanika Journal of Science and Technology 29:1.
Crossref
Qi Su, Lidan Hou, Yuan Gao, Xiaofeng Liu, Zhizhong Cui, Shuang Chang & Peng Zhao. (2020) Research Note: Molecular relationship of the fowl adenovirus serotype 4 isolated from the contaminated live vaccine and wild strains isolated in China, 2013-2018. Poultry Science 99:12, pages 6643-6646.
Crossref
Dongdong Yin, Mei Xue, Kankan Yang, Xiuqi Xiong, Shu Geng, Jian Tu, Xiangjun Song, Ying Shao, Guijun Wang & Kezong Qi. (2020) Molecular characterization and pathogenicity of highly pathogenic fowl adenovirus serotype 4 isolated from laying flock with hydropericardium-hepatitis syndrome. Microbial Pathogenesis 147, pages 104381.
Crossref
Weikang Wang, Qian Liu, Tuofan Li, Tuoyu Geng, Hongjun Chen, Quan Xie, Hongxia Shao, Zhimin Wan, Aijian Qin & Jianqiang Ye. (2020) Fiber-1, Not Fiber-2, Directly Mediates the Infection of the Pathogenic Serotype 4 Fowl Adenovirus via Its Shaft and Knob Domains. Journal of Virology 94:17.
Crossref
Ruxin Liu, Yuhan Zhang, Huifang Guo, Ning Li, Baiyu Wang, Kaiyue Tian, Zeng Wang, Xia Yang, Yongtao Li, Hailong Wang, Youming Zhang, Jun Fu & Jun Zhao. (2020) The increased virulence of hypervirulent fowl adenovirus 4 is independent of fiber-1 and penton. Research in Veterinary Science 131, pages 31-37.
Crossref
Bingyu Yan, Xiaohui Zou, Xinglong Liu, Jiaming Zhao, Wenfeng Zhang, Xiaojuan Guo, Min Wang, Yingtao Lv & Zhuozhuang Lu. (2020) User-Friendly Reverse Genetics System for Modification of the Right End of Fowl Adenovirus 4 Genome. Viruses 12:3, pages 301.
Crossref
Mingliang Zhao, Xueyan Duan, Yongqiang Wang, Li Gao, Hong Cao, Xiaoqi Li & Shijun J. Zheng. (2020) A Novel Role for PX, a Structural Protein of Fowl Adenovirus Serotype 4 (FAdV4), as an Apoptosis-Inducer in Leghorn Male Hepatocellular Cell. Viruses 12:2, pages 228.
Crossref
Cuiteng Chen, Chunhe Wan, Shaohua Shi, Longfei Cheng, Zhen Chen, Guanghua Fu, Rongchang Liu, Chunhua Zhu & Yu Huang. (2019) Development and application of a fiber2 protein-based indirect ELISA for detection of duck adenovirus 3. Molecular and Cellular Probes 48, pages 101447.
Crossref
Zeng Wang & Jun Zhao. (2019) Pathogenesis of Hypervirulent Fowl Adenovirus Serotype 4: The Contributions of Viral and Host Factors. Viruses 11:8, pages 741.
Crossref
Junfeng Gao, Mingliang Zhao, Xueyan Duan, Yongqiang Wang, Hong Cao, Xiaoqi Li & Shijun Zheng. (2019) Requirement of Cellular Protein CCT7 for the Replication of Fowl Adenovirus Serotype 4 (FAdV-4) in Leghorn Male Hepatocellular Cells Via Interaction with the Viral Hexon Protein. Viruses 11:2, pages 107.
Crossref