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Experimental Surgery

The Effects of Desferrioxamine and Quercetin on Liver Injury Induced by Hepatic Ischaemia-Reperfusion in Rats

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Pages 68-72 | Published online: 11 Mar 2016

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Georgios Kyriakopoulos, Alexandra K. Tsaroucha, Georgia Valsami, Maria Lambropoulou, Nikolaos Kostomitsopoulos, Eirini Christodoulou, Zacharias Kakazanis, Constantinos Anagnostopoulos, Christos Tsalikidis & Constantinos E. Simopoulos. (2018) Silibinin Improves TNF-α and M30 Expression and Histological Parameters in Rat Kidneys After Hepatic Ischemia/Reperfusion. Journal of Investigative Surgery 31:3, pages 201-209.
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Oluwatobi T. Somade, Samuel K. Olorode, Tunde O. Olaniyan & Opeyemi Faokunla. (2016) Quercetin, a polyphenolic phytochemical prevents sodium azide-induced extra-hepatic oxidative stress in rats. Cogent Biology 2:1.
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Aparajita Ghosh, Ardhendu K. Mandal, Sibani Sarkar & Nirmalendu Das. (2011) Hepatoprotective and neuroprotective activity of liposomal quercetin in combating chronic arsenic induced oxidative damage in liver and brain of rats. Drug Delivery 18:6, pages 451-459.
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Maria. A. Kyriazi, Kassiani Theodoraki, Theodosios Thedosopoulos, Paraskevi Tsiantoula, George Fragulidis, Georgia Kostopanagiotou, Vassilios Smyrniotis & Nikolaos Arkadopoulos. (2011) Evaluation of Ischemia-Reperfusion Liver Injury by Near-Infrared Spectroscopy in an Experimental Swine Model: The Effect of Desferoxamine. Journal of Investigative Surgery 24:4, pages 164-170.
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Toru Shizuma. (2024) Protective effects of quercetin on ischemia/reperfusion-induced liver injury in animal models肝虚血再灌流障害に対するquercetinの肝保護作用. The Japanese Journal of SURGICAL METABOLISM and NUTRITION 58:1, pages 37-40.
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Saba Moradi, Heidar Tavilani, Massoud Saidijam, Mohammad Hashemnia & Asad Vaisi-Raygani. (2021) Kiwifruit supplementation increases the gene expression of ATP-binding cassette transporter A1 and Liver X receptor α in liver and intestine of hamsters fed with high-fat diet. Mediterranean Journal of Nutrition and Metabolism, pages 1-10.
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Christina Mauerhofer, Lukas Grumet, Peter Schemmer, Bettina Leber & Philipp Stiegler. (2021) Combating Ischemia-Reperfusion Injury with Micronutrients and Natural Compounds during Solid Organ Transplantation: Data of Clinical Trials and Lessons of Preclinical Findings. International Journal of Molecular Sciences 22:19, pages 10675.
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Vasileios Kollaras, Georgia Valsami, Maria Lambropoulou, Ourania Konstandi, Nikolaos Kostomistsopoulos, Emmanouil Pikoulis, Constantinos Simopoulos & Alexandra Tsaroucha. (2021) Effect of silibinin on the expression of MMP2, MMP3, MMP9 and TIMP2 in kidney and lung after hepatic ischemia/reperfusion injury in an experimental rat model. Acta Cirúrgica Brasileira 36:9.
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Eniko Manek & Georg A. Petroianu. (2020) Brain delivery of antidotes by polymeric nanoparticles. Journal of Applied Toxicology 41:1, pages 20-32.
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Jia Fu, Jingjuan Huang, Man Lin, Tingting Xie & Tianhui You. (2020) Quercetin Promotes Diabetic Wound Healing via Switching Macrophages From M1 to M2 Polarization. Journal of Surgical Research 246, pages 213-223.
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Abeer Alm-Eldeen, Abeer Khamis, Nabil Elfiky & Randa Ahmad. (2020) Quercetin modulates age-induced changes in the transcript levels of some apoptosis related genes in the skeletal muscles of male rats. Brazilian Journal of Pharmaceutical Sciences 56.
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Ravindra Babu Pingili, Siva Reddy Challa, A. Krishnamanjari Pawar, Vyshnavi Toleti, Tanvija Kodali & Sirisha Koppula. (2019) A systematic review on hepatoprotective activity of quercetin against various drugs and toxic agents: Evidence from preclinical studies. Phytotherapy Research 34:1, pages 5-32.
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R. Nejjari, M. Benabbes, M. Amrani, B. Meddah, M. Bouatia & J. Taoufik. (2019) Phytochemical screening and wound healing activity of Telephium imperati (L.) in rats. South African Journal of Botany 123, pages 147-151.
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Bshayer Alharbi, Laila Fadda & Hanaa M Ali. (2018) Evaluation of the renoprotective effect of nano turmeric against toxic dose of copper sulfate: Role of vascular cell adhesion molecule‐1, kidney injury molecule‐1, and signal transducer and activator of transcription 3 protein expressions. Journal of Biochemical and Molecular Toxicology 33:2.
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Iman O. Sherif & Nora H. Al-Shaalan. (2018) Vildagliptin Attenuates Hepatic Ischemia/Reperfusion Injury via the TLR4/NF- κ B Signaling Pathway . Oxidative Medicine and Cellular Longevity 2018, pages 1-10.
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Ahlam Alhusaini, Iman H. Hasan, Nouf Aldowsari & Njood Alsaadan. (2018) Prophylactic Administration of Nanocurcumin Abates the Incidence of Liver Toxicity Induced by an Overdose of Copper Sulfate: Role of CYP4502E1, NF-κB and Bax Expressions. Dose-Response 16:4, pages 155932581881628.
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Mustafa Ufuk Uylaş, Adnan Şahin, Varol Şahintürk & İbrahim Özkan Alataş. (2018) Quercetin dose affects the fate of hepatic ischemia and reperfusion injury in rats: An experimental research. International Journal of Surgery 53, pages 117-121.
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Dhivya Sivaraj, Saravanan Shanmugam, Murugan Rajan, Sreeja Puthanpura Sasidharan, Saikumar Sathyanarayanan, Kasipandi Muniyandi, Parimelazhagan Thangaraj & Adriano Antunes de Souza Araújo. (2018) Evaluation of Aristolochia indica L. and Piper nigrum L. methanol extract against centipede Scolopendra moristans L. using Wistar albino rats and screening of bioactive compounds by high pressure liquid chromatography: a polyherbal formulation. Biomedicine & Pharmacotherapy 97, pages 1603-1612.
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Vinay Kant, Babu Lal Jangir, Ankit Nigam, Vinod Kumar & Sonu Sharma. (2017) Dose regulated cutaneous wound healing potential of quercetin in male rats. Wound Medicine 19, pages 82-87.
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Liwei Wu, Chengfen Wang, Jingjing Li, Sainan Li, Jiao Feng, Tong Liu, Shizan Xu, Wenwen Wang, Xiya Lu, Kan Chen, Yujing Xia, Xiaoming Fan & Chuanyong Guo. (2017) Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis. Biomedicine & Pharmacotherapy 96, pages 1137-1146.
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Yara Atef, Hassan M. El-Fayoumi, Yousra Abdel-Mottaleb & Mona F. Mahmoud. (2017) Quercetin and tin protoporphyrin attenuate hepatic ischemia reperfusion injury: role of HO-1. Naunyn-Schmiedeberg's Archives of Pharmacology 390:9, pages 871-881.
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M. BARTEKOVA, J. RADOSINSKA, D. PANCZA, M. BARANCIK & T. RAVINGEROVA. (2016) Cardioprotective Effects of Quercetin Against Ischemia-Reperfusion Injury Are Age-Dependent. Physiological Research, pages S101-S107.
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Aya Mohammed, Ekram N Abd Al Haleem, Wesam M El‐Bakly & Ebtehal El‐Demerdash. (2016) Deferoxamine alleviates liver fibrosis induced by CC l 4 in rats . Clinical and Experimental Pharmacology and Physiology 43:8, pages 760-768.
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Mohamed Abd-Elbaset, El-Shaimaa A. Arafa, Gamal A. El Sherbiny, Mohamed S. Abdel-Bakky & Abdel Nasser A.M. Elgendy. (2015) Quercetin modulates iNOS, eNOS and NOSTRIN expressions and attenuates oxidative stress in warm hepatic ischemia-reperfusion injury in rats. Beni-Suef University Journal of Basic and Applied Sciences 4:3, pages 246-255.
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Suleyman Ayvaz, Mustafa Inan, Burhan Aksu, Turan Karaca, Mustafa Cemek, Ahmet Ayaz, Umit Nusret Basaran & Mehmet Pul. (2014) Desferrioxamine effectively attenuates testicular tissue at the end of 3?h of ischemia but not in an equal period of reperfusion. Journal of Pediatric Urology 10:3, pages 550-558.
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Éder Marcolin, Luiz Felipe Forgiarini, Graziella Rodrigues, Juliana Tieppo, Greice Stefani Borghetti, Valquiria Linck Bassani, Jaqueline Nascimento Picada & Norma Possa Marroni. (2013) Retracted: Quercetin Decreases Liver Damage in Mice with Non‐Alcoholic Steatohepatitis . Basic & Clinical Pharmacology & Toxicology 112:6, pages 385-391.
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Dae-Keun Kwon, Jun-Yong Kang, Jin-Ho Park, Sung-Pil Ryu & Young-Ju Song. (2012) Effects of Opuntia humifusa Supplementation on Lipid Peroxidation and SOD Protein Expression in the Liver, Kidney, and Skeletal Muscle of Rats Fed a High-fat Diet. Journal of Life Science 22:7, pages 857-862.
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Panagiotis Varsos, Constantinos Nastos, Nikolaos Papoutsidakis, Konstantinos Kalimeris, George Defterevos, Tzortzis Nomikos, Agathi Pafiti, George Fragulidis, Emmanuel Economou, Georgia Kostopanagiotou, Vassilios Smyrniotis & Nikolaos Arkadopoulos. (2012) Desferrioxamine Attenuates Pancreatic Injury after Major Hepatectomy under Vascular Control of the Liver: Experimental Study in Pigs. HPB Surgery 2012, pages 1-6.
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Ahmet Kahraman, Hamdullah Çakar & Tülay Köken. (2011) The protective effect of quercetin on long-term alcohol consumption-induced oxidative stress. Molecular Biology Reports 39:3, pages 2789-2794.
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Silvia Bona, Lidiane Isabel Filippin, Fábio Cangeri Di Naso, Cintia de David, Bruna Valiatti, Maximiliano Isoppo Schaun, Ricardo Machado Xavier & Norma Possa Marroni. (2012) Effect of Antioxidant Treatment on Fibrogenesis in Rats with Carbon Tetrachloride-Induced Cirrhosis. ISRN Gastroenterology 2012, pages 1-7.
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Y. Li, P.-J. Zhang, C. Jin, B. Zhou, X.-Y. Liu, L.-D. Tao & M. Feng. (2011) Protective Effects of Deferoxamine Mesylate Preconditioning on Pancreatic Tissue in Orthotopic Liver Autotransplantation in Rats. Transplantation Proceedings 43:5, pages 1450-1455.
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Constantinos Nastos, Konstantinos Kalimeris, Nikolaos Papoutsidakis, George Defterevos, Agathi Pafiti, Helen Kalogeropoulou, Loukia Zerva, Tzortzis Nomikos, Georgia Kostopanagiotou, Vasillios Smyrniotis & Nikolaos Arkadopoulos. (2011) Antioxidant Treatment Attenuates Intestinal Mucosal Damage and Gut Barrier Dysfunction After Major Hepatectomy. Study in a Porcine Model. Journal of Gastrointestinal Surgery 15:5, pages 809-817.
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Emanuelle Kerber Vieira, Silvia Bona, Fábio Cangeri Di Naso, Marilene Porawski, Juliana Tieppo & Norma Possa Marroni. (2011) Quercetin Treatment Ameliorates Systemic Oxidative Stress in Cirrhotic Rats. ISRN Gastroenterology 2011, pages 1-6.
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Aparajita Ghosh, Ardhendu K. Mandal, Sibani Sarkar, Subhamay Panda & Nirmalendu Das. (2009) Nanoencapsulation of quercetin enhances its dietary efficacy in combating arsenic-induced oxidative damage in liver and brain of rats. Life Sciences 84:3-4, pages 75-80.
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Ping Yao, Andreas Nussler, Liegang Liu, Liping Hao, Fangfang Song, Anja Schirmeier & Natascha Nussler. (2007) Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. Journal of Hepatology 47:2, pages 253-261.
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Ardhendu K. Mandal, Subhankar Das, Mukul K. Basu, Rohini N. Chakrabarti & Nirmalendu Das. (2007) Hepatoprotective Activity of Liposomal Flavonoid against Arsenite-Induced Liver Fibrosis. Journal of Pharmacology and Experimental Therapeutics 320:3, pages 994-1001.
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