Citations (149)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Jamie S McConnell, Sandeep Shewale, Niall A Munro, Kalpesh Shah, Angela H Deakin & Andrew WG Kinninmonth. (2011) Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray. Acta Orthopaedica 82:6, pages 660-663.
Read now
Read now
Raimo O Niskanen & Olli L Korkala. (2005) Tranexamic acid reduces blood loss in cemented hip arthroplasty: A randomized, double-blind study of 39 patients with osteoarthritis. Acta Orthopaedica 76:6, pages 829-832.
Read now
Read now
Torsten Johansson, Larsgöran Pettersson & Björn Lisander. (2005) Tranexamic acid in total hip arthroplasty saves blood and money. Acta Orthopaedica 76:3, pages 314-319.
Read now
Read now
Henrik Husted, Lars Blønd, Stig Sonne-Holm, Gitte Holm, Tine Jacobsen & Peter Gebuhr. (2003) Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplastyA prospective randomized double-blind study in 40 patients
. Acta Orthopaedica Scandinavica 74:6, pages 665-669.
Read now
Read now
Articles from other publishers (145)
Victoria N Gibbs, Rita Champaneria, Josie Sandercock, Nicky J Welton, Louise J Geneen, Susan J Brunskill, Carolyn Dorée, Catherine Kimber, Antony JR Palmer & Lise J Estcourt. (2024) Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a systematic review and network meta-analysis. Cochrane Database of Systematic Reviews 2024:1.
Crossref
Crossref
Carsten Perka, Christian von Heymann, Heiko Lier, Lutz Kaufner & Sascha Treskatsch. (2023) The Perioperative Application of Tranexamic Acid. Zeitschrift für Orthopädie und Unfallchirurgie 161:05, pages 532-537.
Crossref
Crossref
Victoria N Gibbs, Louise J Geneen, Rita Champaneria, Parag Raval, Carolyn Dorée, Susan J Brunskill, Alex Novak, Antony JR Palmer & Lise J Estcourt. (2023) Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures. Cochrane Database of Systematic Reviews 2023:6.
Crossref
Crossref
Che Zheng, Jun Ma, Jiawen Xu, Liming Wu, Yuangang Wu, Yuan Liu & Bin Shen. (2023) The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis. Thrombosis Research 221, pages 120-129.
Crossref
Crossref
Guo-Chun Zha, Xian-Ren Zhu, Lei Wang & Hong-Wei Li. (2022) Tranexamic acid reduces blood loss in primary total hip arthroplasty performed using the direct anterior approach: a one-center retrospective observational study. Journal of Orthopaedics and Traumatology 23:1.
Crossref
Crossref
Dennis King-Hang Yee, Janus Siu Him Wong, Evan Fang, Tak-Man Wong, Christian Fang & Frankie Leung. (2022) Topical administration of tranexamic acid in elderly patients undergoing short femoral nailing for intertrochanteric fracture: A randomised controlled trial. Injury 53:2, pages 603-609.
Crossref
Crossref
Karim Z. Masrouha, Zabrina M. Shabin, Kiran Bhutada, Debra A. Sala, David H. Godfried & Mara S. Karamitopoulos. (2021) Impact of tranexamic acid on blood loss and transfusion rate in children with cerebral palsy undergoing hip reconstruction with two or more osteotomies. European Journal of Orthopaedic Surgery & Traumatology 32:2, pages 287-291.
Crossref
Crossref
Isabel Taeuber, Stephanie Weibel, Eva Herrmann, Vanessa Neef, Tobias Schlesinger, Peter Kranke, Leila Messroghli, Kai Zacharowski, Suma Choorapoikayil & Patrick Meybohm. (2021) Association of Intravenous Tranexamic Acid With Thromboembolic Events and Mortality. JAMA Surgery 156:6, pages e210884.
Crossref
Crossref
Christina Pempe, Robert Werdehausen, Philip Pieroh, Martin Federbusch, Sirak Petros, Reinhard Henschler, Andreas Roth & Christian Pfrepper. (2021) Predictors for blood loss and transfusion frequency to guide blood saving programs in primary knee- and hip-arthroplasty. Scientific Reports 11:1.
Crossref
Crossref
Bisola Salaja, Darren Patrick Moloney, Iain Feeley, Andrew Hughes, Kevin Clesham, Denise Murphy, Khalid Merghani & Eoin Sheehan. (2021) The Clinical Significance of Full Blood Count Day 1 Post-op After Total Joint Arthroplasty. SN Comprehensive Clinical Medicine 3:2, pages 654-658.
Crossref
Crossref
Davide Reale, Luca Andriolo, Safa Gursoy, Murat Bozkurt, Giuseppe Filardo & Stefano Zaffagnini. (2021) Complications of Tranexamic Acid in Orthopedic Lower Limb Surgery: A Meta-Analysis of Randomized Controlled Trials. BioMed Research International 2021, pages 1-14.
Crossref
Crossref
Shih-Hsiang Yen, Po-Chun Lin, Cheng-Ta Wu & Jun-Wen Wang. (2021) Comparison of Effects of a Thrombin-Based Hemostatic Agent and Topical Tranexamic Acid on Blood Loss in Patients with Preexisting Thromboembolic Risk Undergoing a Minimally Invasive Total Knee Arthroplasty. A Prospective Randomized Controlled Trial. BioMed Research International 2021, pages 1-8.
Crossref
Crossref
Ji Young Yoon, Joo Hyun Park, Yang Soo Kim, Sang Jin Shin, Jae Chul Yoo & Joo Han Oh. (2020) Effect of tranexamic acid on blood loss after reverse total shoulder arthroplasty according to the administration method: a prospective, multicenter, randomized, controlled study. Journal of Shoulder and Elbow Surgery 29:6, pages 1087-1095.
Crossref
Crossref
Mohamed Sukeik, Sattar Alshryda, James Powell & Fares S. Haddad. (2020) The effect of tranexamic acid on wound complications in primary total Hip Arthroplasty: A meta-analysis. The Surgeon 18:1, pages 53-61.
Crossref
Crossref
Steven B. Porter, Launia J. White, Osayande Osagiede, Christopher B. Robards & Aaron C. Spaulding. (2020) Tranexamic Acid Administration Is Not Associated With an Increase in Complications in High-Risk Patients Undergoing Primary Total Knee or Total Hip Arthroplasty: A Retrospective Case-Control Study of 38,220 Patients. The Journal of Arthroplasty 35:1, pages 45-51.e3.
Crossref
Crossref
Javahir A. Pachore, Vikram Indrajit Shah, Sachin Upadhyay, Kalpesh Shah, Ashish Sheth & Amish Kshatriya. (2019) The use of tranexamic acid to reduce blood loss in uncemented total hip arthroplasty for avascular necrosis of femoral head: a prospective blinded randomized controlled study. Arthroplasty 1:1.
Crossref
Crossref
Zhihu Zhao, Jianxiong Ma & Xinlong Ma. (2019) Comparative efficacy and safety of different hemostatic methods in total hip arthroplasty: a network meta-analysis. Journal of Orthopaedic Surgery and Research 14:1.
Crossref
Crossref
Dae-Kyung Kwak, Chul-Young Jang, Dae-Hwan Kim, Sang-Hyun Rhyu, Ji-Hyo Hwang & Je-Hyun Yoo. (2019) Topical tranexamic acid in elderly patients with femoral neck fractures treated with hemiarthroplasty: efficacy and safety? - a case-control study. BMC Musculoskeletal Disorders 20:1.
Crossref
Crossref
Matthew D Free, David H Owen, Edward Pascoe, Penny Allen, Luke Yang & Paul Harvie. (2018) Transfusion rates with intravenous tranexamic acid in total hip arthroplasty performed using the direct anterior approach. HIP International 29:5, pages 511-515.
Crossref
Crossref
Shazaan F. Hushmendy & Fred D. Cushner. (2019) Avoiding Complications Associated With Anemia Following Total Joint Arthroplasty. Techniques in Orthopaedics 34:3, pages 146-154.
Crossref
Crossref
J. T. HinesN. M. HernandezA. W. AmundsonM. W. PagnanoR. J. SierraM. P. Abdel. (2019) Intravenous tranexamic acid safely and effectively reduces transfusion rates in revision total hip arthroplasty. The Bone & Joint Journal 101-B:6_Supple_B, pages 104-109.
Crossref
Crossref
Sandeep Kashyap, Shweta Mahajan & Mukand Lal. (2019) Effects of topical tranexamic acid during open reduction and internal fixation of acetabular fractures: A retrospective study. Acta Orthopaedica et Traumatologica Turcica 53:3, pages 175-179.
Crossref
Crossref
Jeffrey Yates, Iris Perelman, Simonne Khair, Joshua Taylor, Jacinthe Lampron, Alan Tinmouth & Elianna Saidenberg. (2018) Exclusion criteria and adverse events in perioperative trials of tranexamic acid: a systematic review and meta‐analysis. Transfusion 59:2, pages 806-824.
Crossref
Crossref
Qi Sun, Jinyu Li, Jiang Chen, Chenying Zheng, Chuyin Liu & Yusong Jia. (2019) Comparison of intravenous, topical or combined routes of tranexamic acid administration in patients undergoing total knee and hip arthroplasty: a meta-analysis of randomised controlled trials. BMJ Open 9:1, pages e024350.
Crossref
Crossref
Young-Hoo Kim, Ketan Pandey, Jang-Won Park & Jun-Shik Kim. (2018) Comparative Efficacy of Intravenous With Intra-articular Versus Intravenous Only Administration of Tranexamic Acid to Reduce Blood Loss in Knee Arthroplasty. Orthopedics 41:6.
Crossref
Crossref
Byung-Ho Yoon, Tae-young Kim, Young Seung Ko, Young-Kyun Lee, Yong-Chan Ha & Kyung-Hoi Koo. (2018) Optimal use of tranexamic acid for total hip arthroplasty: A network meta-analysis. PLOS ONE 13:10, pages e0206480.
Crossref
Crossref
Yale A. Fillingham, Dipak B. Ramkumar, David S. Jevsevar, Adolph J. Yates, Peter Shores, Kyle Mullen, Stefano A. Bini, Henry D. Clarke, Emil Schemitsch, Rebecca L. Johnson, Stavros G. Memtsoudis, Siraj A. Sayeed, Alexander P. Sah & Craig J. Della Valle. (2018) The Efficacy of Tranexamic Acid in Total Hip Arthroplasty: A Network Meta-analysis. The Journal of Arthroplasty 33:10, pages 3083-3089.e4.
Crossref
Crossref
Yale A. Fillingham, Dipak B. Ramkumar, David S. Jevsevar, Adolph J. Yates, Peter Shores, Kyle Mullen, Stefano A. Bini, Henry D. Clarke, Emil Schemitsch, Rebecca L. Johnson, Stavros G. Memtsoudis, Siraj A. Sayeed, Alexander P. Sah & Craig J. Della Valle. (2018) The Safety of Tranexamic Acid in Total Joint Arthroplasty: A Direct Meta-Analysis. The Journal of Arthroplasty 33:10, pages 3070-3082.e1.
Crossref
Crossref
Seher Orbay Yaşlı, Zeynep Tosun, Mehmet Halıcı & Selda Kahraman Kayaaltı. (2018) Effects of high-dose tranexamic acid in total hip replacement: A prospective, double-blind, randomized controlled study. Journal of Surgery and Medicine.
Crossref
Crossref
Andrew Fraval, Sam Duncan, Theresa Murray, Jeremy Duggan, Oren Tirosh & Phong Tran. (2018) OBTAIN E: outcome benefits of tranexamic acid in hip arthroplasty with enoxaparin: a randomised double-blinded controlled trial. HIP International, pages 112070001878012.
Crossref
Crossref
Dipak B. Ramkumar, Niveditta Ramkumar, Stephanie J. Tapp & Wayne E. Moschetti. (2018) Pharmacologic Hemostatic Agents in Total Joint Arthroplasty—A Cost-Effectiveness Analysis. The Journal of Arthroplasty 33:7, pages 2092-2099.e9.
Crossref
Crossref
Yufu Ou, Jianxun Wei, Rongzhu Li, Bin Liang, Dezan Qiu, Minke Wei, Xiaoping Mu & Zhuhai Li. (2018) Clinical Research of Combined Intravenous Administration and Topical Application of Tranexamic Acid to a Surgical Wound During Posterior Lumbar Fusion. Surgical Innovation 25:2, pages 128-135.
Crossref
Crossref
Kannan Sridharan & Gowri Sivaramakrishnan. (2018) Tranexamic acid in total hip arthroplasty: Mixed treatment comparisons of randomized controlled trials and cohort studies. Journal of Orthopaedics 15:1, pages 81-88.
Crossref
Crossref
Shuwei Tian, Zheyuan Shen, Yang Liu, Yanlong Zhang & Aqin Peng. (2018) The effect of tranexamic acid on hidden bleeding in older intertrochanteric fracture patients treated with PFNA. Injury 49:3, pages 680-684.
Crossref
Crossref
Julien Lanoiselée, Paul J. Zufferey, Edouard Ollier, Sophie Hodin & Xavier Delavenne. (2017) Is tranexamic acid exposure related to blood loss in hip arthroplasty? A pharmacokinetic–pharmacodynamic study. British Journal of Clinical Pharmacology 84:2, pages 310-319.
Crossref
Crossref
Ramakrishna Prasad, Abhiruchi Patki, Shibany Padhy & Gopinath Ramchandran. (2018) Single intravenous bolus versus perioperative continuous infusion of tranexamic acid to reduce blood loss in abdominal oncosurgical procedures: A prospective randomized double-blind clinical study. Journal of Anaesthesiology Clinical Pharmacology 34:4, pages 529.
Crossref
Crossref
Young-Hoo Kim, Jang-Won Park, Jun-Shik Kim & Dong-Hyuk Seo. (2017) Does tranexamic acid increase the risk of thromboembolism after bilateral simultaneous total knee arthroplasties in Asian Population?. Archives of Orthopaedic and Trauma Surgery 138:1, pages 83-89.
Crossref
Crossref
Jianxi Zhu, Yong Zhu, Pengfei Lei, Min Zeng, Weiping Su & Yihe Hu. (2017) Efficacy and safety of tranexamic acid in total hip replacement. Medicine 96:52, pages e9552.
Crossref
Crossref
Weidong Wang & Jincong Yu. (2017) Tranexamic acid reduces blood loss in intertrochanteric fractures. Medicine 96:52, pages e9396.
Crossref
Crossref
William D. LackBrett D. CristRachel B. Seymour, William HarvinMadhav A. Karunakar. (2017) Effect of Tranexamic Acid on Transfusion: A Randomized Clinical Trial in Acetabular Fracture Surgery. Journal of Orthopaedic Trauma 31:10, pages 526-530.
Crossref
Crossref
Aatif Mahmood, Seif Sawalha, Aaron Borbora, Gunasekaran Kumar & Viju Peter. (2017) Tranexamic acid versus fibrin sealant in primary total hip replacement: a comparative study. European Journal of Orthopaedic Surgery & Traumatology 27:7, pages 923-928.
Crossref
Crossref
Kannan Sridharan & Gowri Sivaramakrishnan. (2017) Tranexamic acid in total hip arthroplasty: A recursive cumulative meta-analysis of randomized controlled trials and assessment of publication bias. Journal of Orthopaedics 14:3, pages 323-328.
Crossref
Crossref
Orlando D. Sabbag, Matthew P. Abdel, Adam W. Amundson, Dirk R. Larson & Mark W. Pagnano. (2017) Tranexamic Acid Was Safe in Arthroplasty Patients With a History of Venous Thromboembolism: A Matched Outcome Study. The Journal of Arthroplasty 32:9, pages S246-S250.
Crossref
Crossref
Chad D. Watts, Matthew T. Houdek, S. Andrew Sems, William W. Cross & Mark W. Pagnano. (2017) Tranexamic Acid Safely Reduced Blood Loss in Hemi- and Total Hip Arthroplasty for Acute Femoral Neck Fracture: A Randomized Clinical Trial. Journal of Orthopaedic Trauma 31:7, pages 345-351.
Crossref
Crossref
Josef Hochreiter, Wilfried Hejkrlik, Katja Emmanuel, Wolfgang Hitzl & Reinhold Ortmaier. (2016) Blood loss and transfusion rate in short stem hip arthroplasty. A comparative study. International Orthopaedics 41:7, pages 1347-1353.
Crossref
Crossref
Andrew Fraval, Peter Effeney, Lena Fiddelaers, Belinda Smith, Ben Towell & Phong Tran. (2017) OBTAIN A: Outcome Benefits of Tranexamic Acid in Hip Arthroplasty. A Randomized Double-Blinded Controlled Trial. The Journal of Arthroplasty 32:5, pages 1516-1519.
Crossref
Crossref
Nariaki NakuraKazuo HirakawaSatoshi TakayanagiAkira SaitoKoji TsujiYasunobu TamakiShunsuke OchiaiMasahiko Mihara. (2016) Additional intraarticular tranexamic acid further reduced postoperative blood loss compared to intravenous and topical bathed tranexamic acid in total hip arthroplasty: a retrospective sequential series study. Transfusion 57:4, pages 977-984.
Crossref
Crossref
Erdan Kayupov, Yale A. Fillingham, Kamil Okroj, Darren R. Plummer, Mario Moric, Tad L. Gerlinger & Craig J. Della Valle. (2017) Oral and Intravenous Tranexamic Acid Are Equivalent at Reducing Blood Loss Following Total Hip Arthroplasty. Journal of Bone and Joint Surgery 99:5, pages 373-378.
Crossref
Crossref
Daniel J. Johnson, William W. Yang, Robert A. Sikorski, Harpal S. Khanuja & Steven M. Frank. (2017) Health Policy, Ethical, Business, and Financial Issues Related to Blood Management in Orthopedics. Techniques in Orthopaedics 32:1, pages 51-59.
Crossref
Crossref
Young-Hoo Kim, Jang-Won Park & Jun-Shik Kim. (2017) Chemical Thromboprophylaxis Is Not Necessary to Reduce Risk of Thromboembolism With Tranexamic Acid After Total Hip Arthroplasty. The Journal of Arthroplasty 32:2, pages 641-644.
Crossref
Crossref
Joon Soon Kang, Kyoung Ho Moon, Bom Soo Kim & Seong Jo Yang. (2016) Topical administration of tranexamic acid in hip arthroplasty. International Orthopaedics 41:2, pages 259-263.
Crossref
Crossref
AnilKumar Thipparampall, Indira Gurajala & R Gopinath. (2017) The effect of different dose regimens of tranexamic acid in reducing blood loss during hip surgery. Indian Journal of Anaesthesia 61:3, pages 235.
Crossref
Crossref
Shih-Hsiang Yen, Po-Chun Lin, Bradley Chen, Chung-Chen Huang & Jun-Wen Wang. (2017) Topical Tranexamic Acid Reduces Blood Loss in Minimally Invasive Total Knee Arthroplasty Receiving Rivaroxaban. BioMed Research International 2017, pages 1-8.
Crossref
Crossref
Gustavus Lemos Ribeiro Melo, Daniel Souza Lages, João Lopo Madureira Junior, Guilherme de Paula Pellucci & João Wagner Junqueira Pellucci. (2017) The use of tranexamic acid in patients submitted to primary total hip arthroplasty: an evaluation of its impact in different administration protocols. Revista Brasileira de Ortopedia (English Edition) 52, pages 34-39.
Crossref
Crossref
Gustavus Lemos Ribeiro Melo, Daniel Souza Lages, João Lopo Madureira Junior, Guilherme de Paula Pellucci & João Wagner Junqueira Pellucci. (2017) O uso do ácido tranexâmico em pacientes submetidos a artroplastia total primária do quadril: uma avaliação do seu impacto em diferentes protocolos de administração. Revista Brasileira de Ortopedia 52, pages 34-39.
Crossref
Crossref
Kwan J. Park, Cory G. Couch, Paul K. Edwards, Eric R. Siegel, Simon C. Mears & C. Lowry Barnes. (2016) Tranexamic Acid Reduces Blood Transfusions in Revision Total Hip Arthroplasty. The Journal of Arthroplasty 31:12, pages 2850-2855.e1.
Crossref
Crossref
Joseph T. Moskal & Susan G. Capps. (2016) Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty. Orthopedics 39:5.
Crossref
Crossref
M. Castro-Menéndez, S. Pena-Paz, F. Rocha-García, N. Rodríguez-Casas, R. Huici-Izco & A. Montero-Viéites. (2016) Efficacy of 2 grammes of intravenous transexamic acid in the reduction of post-surgical bleeding after total hip and knee replacement. Revista Española de Cirugía Ortopédica y Traumatología (English Edition) 60:5, pages 315-324.
Crossref
Crossref
M. Castro-Men?ndez, S. Pena-Paz, F. Rocha-Garc?a, N. Rodr?guez-Casas, R. Huici-Izco & A. Montero-Vi?ites. (2016) Eficacia de 2 gramos intravenosos de ?cido tranex?mico en la reducci?n del sangrado postoperatorio de la artroplastia total de cadera y rodilla. Revista Espa?ola de Cirug?a Ortop?dica y Traumatolog?a 60:5, pages 315-324.
Crossref
Crossref
Zeng Yi, Shen Bin, Yang Jing, Zhou Zongke, Kang Pengde & Pei Fuxing. (2016) Tranexamic Acid Administration in Primary Total Hip Arthroplasty. Journal of Bone and Joint Surgery 98:12, pages 983-991.
Crossref
Crossref
Christian Skovgaard Nielsen, Øivind Jans, Thue Ørsnes, Nicolai Bang Foss, Anders Troelsen & Henrik Husted. (2016) Combined Intra-Articular and Intravenous Tranexamic Acid Reduces Blood Loss in Total Knee Arthroplasty. Journal of Bone and Joint Surgery 98:10, pages 835-841.
Crossref
Crossref
Changde Wang, Pengde Kang, Jun Ma, Chen Yue, Jinwei Xie & Fuxing Pei. (2016) Single-dose tranexamic acid for reducing bleeding and transfusions in total hip arthroplasty: A double-blind, randomized controlled trial of different doses. Thrombosis Research 141, pages 119-123.
Crossref
Crossref
Zilan X. Lin & Shane K. Woolf. (2016) Safety, Efficacy, and Cost-effectiveness of Tranexamic Acid in Orthopedic Surgery. Orthopedics 39:2, pages 119-130.
Crossref
Crossref
Joshua B. Holt, Benjamin J. Miller, John J. Callaghan, Charles R. Clark, Melissa D. Willenborg & Nicolas O. Noiseux. (2016) Minimizing Blood Transfusion in Total Hip and Knee Arthroplasty Through a Multimodal Approach. The Journal of Arthroplasty 31:2, pages 378-382.
Crossref
Crossref
Rafal Kaminski. (2016) Administration of tranexamic acid in primary total joint arthroplasty. Clinical and Translational Orthopedics 1:3, pages 118.
Crossref
Crossref
J. PERTLÍČEK, J. STEHLÍK, P. SADOVSKÝ, D. MUSIL & V. MEZERA. (2015) The Effect of Tranexamic Acid on Blood Loss after Primary Unilateral Total Knee Arthroplasty. Prospective Single-Centre Study. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 82:6, pages 418-423.
Crossref
Crossref
Daniel R. Whiting, Christopher M. Duncan, Rafael J. Sierra & Hugh M. Smith. (2015) Tranexamic Acid Benefits Total Joint Arthroplasty Patients Regardless of Preoperative Hemoglobin Value. The Journal of Arthroplasty 30:12, pages 2098-2101.
Crossref
Crossref
Fei Huang, Yunfeng Wu, Zongsheng Yin, Guangwen Ma & Jun Chang. (2018) A Systematic Review and Meta-Analysis of the Use of Antifibrinolytic Agents in Total Hip Arthroplasty. HIP International 25:6, pages 502-509.
Crossref
Crossref
James E. Baker, Katerina Pavenski, Razak A. Pirani, Alexander White, Mark Kataoka, James P. Waddell, Alexander Ho, Emil H. Schemitsch, Nick Lo, Earl R. Bogoch, Antoine Pronovost, Katherine Luke, Alanna Howell, Anna Nassis, Albert K. Y. Tsui, Rosa Maria Tanzini, Robisa Pulendrarajah, C. David Mazer, John Freedman & Gregory M. T. Hare. (2015) Universal tranexamic acid therapy to minimize transfusion for major joint arthroplasty: a retrospective analysis of protocol implementationTraitement universel à l’acide tranexamique pour minimiser les transfusions pendant toute arthroplastie majeure des articulations: une analyse rétrospective suivant la mise en œuvre d’un protocole. Canadian Journal of Anesthesia/Journal canadien d'anesthésie 62:11, pages 1179-1187.
Crossref
Crossref
C-H. HsuP-C. LinF-C. KuoJ-W. Wang. (2015) A regime of two intravenous injections of tranexamic acid reduces blood loss in minimally invasive total hip arthroplasty. The Bone & Joint Journal 97-B:7, pages 905-910.
Crossref
Crossref
Z. Wei & M. Liu. (2015) The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta‐analysis of 2720 cases. Transfusion Medicine 25:3, pages 151-162.
Crossref
Crossref
C.E. Pinzón-Florez, K.M. Vélez Cañas & D.M. Díaz Quijano. (2015) Efficiency of tranexamic acid in perioperative blood loss in hip arthroplasty: A systematic literature review and meta-analysis. Revista Española de Anestesiología y Reanimación (English Edition) 62:5, pages 253-264.
Crossref
Crossref
C.E. Pinzón-Florez, K.M. Vélez Cañas & D.M. Díaz Quijano. (2015) Efectividad del ácido tranexámico en las pérdidas sanguíneas perioperatorias en la artroplastia de cadera: revisión sistemática de la literatura y metaanálisis. Revista Española de Anestesiología y Reanimación 62:5, pages 253-264.
Crossref
Crossref
S. NishiharaM. Hamada. (2015) Does tranexamic acid alter the risk of thromboembolism after total hip arthroplasty in the absence of routine chemical thromboprophylaxis?. The Bone & Joint Journal 97-B:4, pages 458-462.
Crossref
Crossref
Sattar Alshryda, James M. Mason, Praveen Sarda, T. Lou, Martin Stanley, Junjie Wu & Anthony Unsworth. (2014) The effect of tranexamic acid on artificial joint materials: a biomechanical study (the bioTRANX study). Journal of Orthopaedics and Traumatology 16:1, pages 27-34.
Crossref
Crossref
I. Majid, S. Alshryda, B. Somanchi, E. Morakis & A. Foster. (2015) The Value of Tranexamic Acid in Reducing Blood Loss following Hip Reconstruction in Children with Cerebral Palsy. Journal of Blood Transfusion 2015, pages 1-5.
Crossref
Crossref
Chen Yue, Pengde Kang, Peiqing Yang, Jinwei Xie & Fuxing Pei. (2014) Topical Application of Tranexamic Acid in Primary Total Hip Arthroplasty: A Randomized Double-Blind Controlled Trial. The Journal of Arthroplasty 29:12, pages 2452-2456.
Crossref
Crossref
Pradeep S, Jagadish M B & Liyakath Ali. (2014) DOES TRANEXEMIC ACID REDUCE BLO O D TRANSFUSION REQUIREMENTS PERIOPERATIVELY IN PATIENTS UNDERGOING SPINE STABILIZATION SURGERIES? A PROSPECTIVE RANDOMIZED DOUBLE BLINDED CONTROLLED STUDY. Journal of Evolution of Medical and Dental Sciences 3:66, pages 14314-14322.
Crossref
Crossref
S. AlshrydaM. SukeikP. SardaJ. BlenkinsoppF. S. HaddadJ. M. Mason. (2014) A systematic review and meta-analysis of the topical administration of tranexamic acid in total hip and knee replacement. The Bone & Joint Journal 96-B:8, pages 1005-1015.
Crossref
Crossref
Matthew A. Halanski, Jeffrey A. Cassidy, Scott Hetzel, Diann Reischmann & Nabil Hassan. (2014) The Efficacy of Amicar Versus Tranexamic Acid in Pediatric Spinal Deformity Surgery: A Prospective, Randomized, Double-Blinded Pilot Study. Spine Deformity 2:3, pages 191-197.
Crossref
Crossref
Federica Vigna-Taglianti, Leonardo Basso, Paola Rolfo, Romeo Brambilla, Federica Vaccari, Gisella Lanci & Roberto Russo. (2013) Tranexamic acid for reducing blood transfusions in arthroplasty interventions: a cost-effective practice. European Journal of Orthopaedic Surgery & Traumatology 24:4, pages 545-551.
Crossref
Crossref
Mohammad R. Rasouli, Luiz Sérgio Marcelino Gomes, Brian Parsley, Wael Barsoum, Hari Bezwada, James Cashman, Julio Garcia, William Hamilton, Eric Hume, Tae Kyun Kim, Rajesh Malhotra, Stavros G. Memtsoudis, Alvin Ong, Fabio Orozco, Douglas E. Padgett, Ricardo J. Reina, Marco Teloken, Emmanuel Thienpont & Jonathan H. Waters. (2014) Blood Conservation. The Journal of Arthroplasty 29:2, pages 65-70.
Crossref
Crossref
Tyler C. Wind, William R. Barfield & Joseph T. Moskal. (2014) The Effect of Tranexamic Acid on Transfusion Rate in Primary Total Hip Arthroplasty. The Journal of Arthroplasty 29:2, pages 387-389.
Crossref
Crossref
Anas Saleh, Mark Hebeish, Mario Farias-Kovac, Alison K. Klika, Preetesh Patel, Juan Suarez & Wael K. Barsoum. (2014) Use of Hemostatic Agents in Hip and Knee Arthroplasty. JBJS Reviews 2:1.
Crossref
Crossref
X. Aguilera-Roig, M. Jordán-Sales, L. Natera-Cisneros, J.C. Monllau-García & M.J. Martínez-Zapata. (2014) Tranexamic acid in orthopedic surgery. Revista Española de Cirugía Ortopédica y Traumatología (English Edition) 58:1, pages 52-56.
Crossref
Crossref
X. Aguilera-Roig, M. Jordán-Sales, L. Natera-Cisneros, J.C. Monllau-García & M.J. Martínez-Zapata. (2014) Ácido tranexámico en cirugía ortopédica. Revista Española de Cirugía Ortopédica y Traumatología 58:1, pages 52-56.
Crossref
Crossref
Fei Huang, Dan Wu, Guangwen Ma, Zongsheng Yin & Qing Wang. (2014) The use of tranexamic acid to reduce blood loss and transfusion in major orthopedic surgery: a meta-analysis. Journal of Surgical Research 186:1, pages 318-327.
Crossref
Crossref
Jeffrey C. Posnick. 2014. Orthognathic Surgery. Orthognathic Surgery
308
336
.
Daniel R. Whiting, Blake P. Gillette, Christopher Duncan, Hugh Smith, Mark W. Pagnano & Rafael J. Sierra. (2013) Preliminary Results Suggest Tranexamic Acid is Safe and Effective in Arthroplasty Patients with Severe Comorbidities. Clinical Orthopaedics and Related Research® 472:1, pages 66-72.
Crossref
Crossref
. (2014) Blood Conservation. Journal of Orthopaedic Research 32:S1.
Crossref
Crossref
Rajiv Gandhi, Heather MK Evans, Safiyyah R Mahomed & Nizar N Mahomed. (2013) Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis. BMC Research Notes 6:1.
Crossref
Crossref
Sattar Alshryda, James Mason, Praveen Sarda, Antoni Nargol, Nick Cooke, Hafeez Ahmad, S. Tang, Raj Logishetty, Manesh Vaghela, Lynne McPartlin & A. Pali S. Hungin. (2013) Topical (Intra-Articular) Tranexamic Acid Reduces Blood Loss and Transfusion Rates Following Total Hip Replacement. Journal of Bone and Joint Surgery 95:21, pages 1969-1974.
Crossref
Crossref
Blake P. Gillette, Hilal Maradit Kremers, Christopher M. Duncan, Hugh M. Smith, Robert T. Trousdale, Mark W. Pagnano & Rafael J. Sierra. (2013) Economic Impact of Tranexamic Acid in Healthy Patients Undergoing Primary Total Hip and Knee Arthroplasty. The Journal of Arthroplasty 28:8, pages 137-139.
Crossref
Crossref
K Ker, D Prieto-Merino & I Roberts. (2013) Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss. British Journal of Surgery 100:10, pages 1271-1279.
Crossref
Crossref
Xin-die Zhou, Li-jiang Tao, Jin Li & Li-dong Wu. (2013) Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials. Archives of Orthopaedic and Trauma Surgery 133:7, pages 1017-1027.
Crossref
Crossref
Francesco Falez, Antonio Meo, Gabriele Panegrossi, Fabio Favetti, Filippo La Cava & Filippo Casella. (2013) Blood loss reduction in cementless total hip replacement with fibrin spray or bipolar sealer: a randomised controlled trial on ninety five patients. International Orthopaedics 37:7, pages 1213-1217.
Crossref
Crossref
Gerard M. March, Salah Elfatori & Paul E. Beaulé. (2013) Clinical Experience with Tranexamic Acid during Primary Total Hip Arthroplasty. HIP International 23:1, pages 72-79.
Crossref
Crossref
Antonia Blani?Lorenn Bellamy, Yara Rhayem, Claire Flaujac, Charles Marc Samama, Michaela Fontenay & Nadia Rosencher. (2013) Duration of Postoperative Fibrinolysis after Total Hip or Knee Replacement: A Laboratory Follow-up Study. Thrombosis Research 131:1, pages e6-e11.
Crossref
Crossref
Blake P. Gillette, Lori J. DeSimone, Robert T. Trousdale, Mark W. Pagnano & Rafael J. Sierra. (2012) Low Risk of Thromboembolic Complications With Tranexamic Acid After Primary Total Hip and Knee Arthroplasty. Clinical Orthopaedics and Related Research? 471:1, pages 150-154.
Crossref
Crossref
Norio Imai, Yoichiro Dohmae, Ken Suda, Dai Miyasaka, Tomoyuki Ito & Naoto Endo. (2012) Tranexamic Acid for Reduction of Blood Loss During Total Hip Arthroplasty. The Journal of Arthroplasty 27:10, pages 1838-1843.
Crossref
Crossref
Hussain A. Kazi, James R. Fountain, T. Glyn Thomas & Fintan A. Carroll. (2018) The Effect of Bolus Administration of Tranexamic Acid in Revision Hip Arthroplasty. HIP International 22:6, pages 615-620.
Crossref
Crossref
Tamás de Jonge. (2012) Pharmacological reduction of bleeding during hip endoprosthetic replacement. Orvosi Hetilap 153:41, pages 1607-1612.
Crossref
Crossref
A. Clavé, F. Fazilleau, D. Dumser & J. Lacroix. (2012) Efficacité de l’acide tranexamique sur la perte sanguine postopératoire après prothèse totale de hanche sans ciment de première intention dans le cadre d’une prophylaxie thromboembolique par rivaoxaban : une étude de 70 patients en « cas–témoin ». Revue de Chirurgie Orthopédique et Traumatologique 98:5, pages 426-433.
Crossref
Crossref
A. Clavé, F. Fazilleau, D. Dumser & J. Lacroix. (2012) Efficacy of tranexamic acid on blood loss after primary cementless total hip replacement with rivaroxaban thromboprophylaxis: A case-control study in 70 patients. Orthopaedics & Traumatology: Surgery & Research 98:5, pages 484-490.
Crossref
Crossref
Anthony R. Bradshaw, Jennifer Monoghan & David Campbell. (2012) Oral tranexamic acid reduces blood loss in total knee replacement arthroplasty. Current Orthopaedic Practice 23:3, pages 209-212.
Crossref
Crossref
Paul L. McCormack. (2012) Tranexamic Acid. Drugs 72:5, pages 585-617.
Crossref
Crossref
Michael P. Nett. 2012. Partial Knee Arthroplasty. Partial Knee Arthroplasty
247
257
.
Michael P. Nett, William J. Long & Fred D. Cushner. 2012. Insall & Scott Surgery of the Knee. Insall & Scott Surgery of the Knee
e141-1
e141-12
.
Fritz E. Gempeler R.Ana Helena Perea B.Lorena D?az B.. (2011) Tromboelastograf?a. Revista Colombiana de Anestesiolog?a 39:3, pages 410-423.
Crossref
Crossref
A. Stachura, R. Król, T. Poplawski, D. Michalik, S. Pomianowski, M. Jacobsson, M. Åberg & A. Bengtsson. (2010) Transfusion of intra‐operative autologous whole blood: Influence on complement activation and interleukin formation. Vox Sanguinis 100:2, pages 239-246.
Crossref
Crossref
Rajesh Malhotra, Vijay Kumar & Bhavuk Garg. (2010) The use of tranexamic acid to reduce blood loss in primary cementless total hip arthroplasty. European Journal of Orthopaedic Surgery & Traumatology 21:2, pages 101-104.
Crossref
Crossref
David A Henry, Paul A Carless, Annette J Moxey, Dianne O'Connell, Barrie J Stokes, Dean A Fergusson & Katharine Ker. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
M. SukeikS. AlshrydaF. S. HaddadJ. M. Mason. (2011) Systematic review and meta-analysis of the use of tranexamic acid in total hip replacement. The Journal of Bone and Joint Surgery. British volume 93-B:1, pages 39-46.
Crossref
Crossref
Jagwant Singh, Moez S Ballal, P Mitchell & PG Denn. (2010) Effects of Tranexamic Acid on Blood Loss during Total Hip Arthroplasty. Journal of Orthopaedic Surgery 18:3, pages 282-286.
Crossref
Crossref
Richard J. Friedman. (2010) Limit the Bleeding, Limit the Pain in Total Hip and Knee Arthroplasty. Orthopedics 33:9, pages 11-13.
Crossref
Crossref
Jeffrey F. Barletta, Brad Cooper & Martin J. Ohlinger. (2010) Adverse drug events associated with disorders of coagulation. Critical Care Medicine 38, pages S198-S218.
Crossref
Crossref
C. Vuillaume, R. Fuzier, J.-P. Magues, A.-S. Richez, B. Bataille & P. Bonnevialle. (2010) Place des stratégies d’épargne sanguine en peropératoire et postopératoire immédiat en chirurgie arthroplastique primaire de hanche et de genou : enquête nationale en France. Revue de Chirurgie Orthopédique et Traumatologique 96:2, pages 242-247.
Crossref
Crossref
R M Tikhilov, I I Shubnyakov, M I Mokhanna, D G Pliev, A A Myasoedov, A V Tsybin, A V Ambrosenko, V V Bliznyukov, I T Chiladze & D A Shulepov. (2010) Efficacy of Tranexamic Acid Application for Blood Loss Reduction in Total Hip Arthroplasty. N.N. Priorov Journal of Traumatology and Orthopedics 17:1, pages 29-34.
Crossref
Crossref
Yves Ozier & Lorenn Bellamy. (2010) Pharmacological agents: antifibrinolytics and desmopressin. Best Practice & Research Clinical Anaesthesiology 24:1, pages 107-119.
Crossref
Crossref
. (2010) The Effect of Tranexamic Acid on Reducing Blood Loss in Cementless Total Hip Arthroplasty Under Epidural Anesthesia. Orthopedics 33:1.
Crossref
Crossref
P.J. Zufferey, M. Miquet, S. Quenet, P. Martin, P. Adam, P. Albaladejo, P. Mismetti & S. Molliex. (2010) Tranexamic acid in hip fracture surgery: a randomized controlled trial. British Journal of Anaesthesia 104:1, pages 23-30.
Crossref
Crossref
Nadezhda Ivanovna Arzhakova, A I Bernakevich, E V Shushpanova, N I Arzhakova, A I Bernakevich & E V Shushpanova. (2009) Blood Saving Effect of Tranexame at Hip Joint Replacement. N.N. Priorov Journal of Traumatology and Orthopedics 16:4, pages 13-18.
Crossref
Crossref
K. RajesparanL. C. BiantM. AhmadR. E. Field. (2009) The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement. The Journal of Bone and Joint Surgery. British volume 91-B:6, pages 776-783.
Crossref
Crossref
J Brian Gill, Emily Chase & Alexander D Rosenstein. (2009) The use of tranexamic acid in revision total hip arthroplasty: a pilot study. Current Orthopaedic Practice 20:2, pages 152-156.
Crossref
Crossref
Yoan K. Kagoma, Mark A. Crowther, James Douketis, Mohit Bhandari, John Eikelboom & Wendy Lim. (2009) Use of antifibrinolytic therapy to reduce transfusion in patients undergoing orthopedic surgery: A systematic review of randomized trials. Thrombosis Research 123:5, pages 687-696.
Crossref
Crossref
G.S. Caglar, Y. Tasci, F. Kayikcioglu & A. Haberal. (2008) Intravenous tranexamic acid use in myomectomy: A prospective randomized double-blind placebo controlled study. European Journal of Obstetrics & Gynecology and Reproductive Biology 137:2, pages 227-231.
Crossref
Crossref
Juan C. Álvarez, Francisco X. Santiveri, Isabel Ramos, Enrique Vela, Lluis Puig & Fernando Escolano. (2007) Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied. Transfusion 48:3, pages 519-525.
Crossref
Crossref
David A Henry, Paul A Carless, Annette J Moxey, Dianne O'Connell, Barrie J Stokes, Brian McClelland, Andreas Laupacis & Dean A Fergusson. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Paul Zufferey, Fanette Merquiol, Silvy Laporte, Herv?? Decousus, Patrick Mismetti, Christian Auboyer, Charles Marc Samama & Serge Molliex. (2006) Do Antifibrinolytics Reduce Allogeneic Blood Transfusion in Orthopedic Surgery?. Anesthesiology 105:5, pages 1034-1046.
Crossref
Crossref
J. Brian Gill & Alexander Rosenstein. (2006) The Use of Antifibrinolytic Agents in Total Hip Arthroplasty. The Journal of Arthroplasty 21:6, pages 869-873.
Crossref
Crossref
Dan Drobin, Fredrik Sjostrand, David Piros, Annika Hedin, Goran Heinius & Robert G. Hahn. (2005) Tranexamic Acid Does Not Prevent Rebleeding in an Uncontrolled Hemorrhage Porcine Model. Journal of Trauma: Injury, Infection & Critical Care 59:4, pages 976-983.
Crossref
Crossref
Satoshi Yamasaki, Kensaku Masuhara & Takeshi Fuji. (2005) Tranexamic Acid Reduces Postoperative Blood Loss in Cementless Total Hip Arthroplasty. The Journal of Bone & Joint Surgery 87:4, pages 766-770.
Crossref
Crossref
SATOSHI YAMASAKI, KENSAKU MASUHARA & TAKESHI FUJI. (2005) TRANEXAMIC ACID REDUCES POSTOPERATIVE BLOOD LOSS IN CEMENTLESS TOTAL HIP ARTHROPLASTY. The Journal of Bone and Joint Surgery-American Volume 87:4, pages 766-770.
Crossref
Crossref
Navil F. Sethna, David Zurakowski, Robert M. Brustowicz, Julianne Bacsik, Lorna J. Sullivan & Frederic Shapiro. (2005) Tranexamic Acid Reduces Intraoperative Blood Loss in Pediatric Patients Undergoing Scoliosis Surgery. Anesthesiology 102:4, pages 727-732.
Crossref
Crossref
A.M. Mahdy & N.R. Webster. (2004) Perioperative systemic haemostatic agents. British Journal of Anaesthesia 93:6, pages 842-858.
Crossref
Crossref
Gwo-Chin Lee & Fred D Cushner. (2004) Blood Management in Patients with Deep Prosthetic Hip and Knee Infections. Orthopedics 27:6.
Crossref
Crossref
Mark Tenholder & Fred D Cushner. (2004) Intraoperative Blood Management in Joint Replacement Surgery. Orthopedics 27:6.
Crossref
Crossref
Göran Zellin, Lars Rasmusson, Jan Pålsson & K.-E Kahnberg. (2004) Evaluation of hemorrhage depressors on blood loss during orthognathic surgery: a retrospective study. Journal of Oral and Maxillofacial Surgery 62:6, pages 662-666.
Crossref
Crossref
Narendra Garneti & Jeremy Field. (2004) Bone bleeding during total hip arthroplasty after administration of tranexamic acid. The Journal of Arthroplasty 19:4, pages 488-492.
Crossref
Crossref
Erik Lemay, Joanne Guay, Christiane Côté & Alain Roy. (2004) Tranexamic acid reduces the need for allogenic red blood cell transfusions in patients undergoing total hip replacementL’acide tranexamique réduit les besoins de transfusion sanguine allogénique chez les patients devant subir une arthroplastie totale de la hanche. Canadian Journal of Anesthesia/Journal canadien d'anesthésie 51:1, pages 31-37.
Crossref
Crossref
M. Hynes, P. Calder & G. Scott. (2003) The use of tranexamic acid to reduce blood loss during total knee arthroplasty. The Knee 10:4, pages 375-377.
Crossref
Crossref
K. M. Ho & H. Ismail. (2019) Use of Intravenous Tranexamic Acid to Reduce Allogeneic Blood Transfusion in Total Hip and Knee Arthroplasty: A Meta-analysis. Anaesthesia and Intensive Care 31:5, pages 529-537.
Crossref
Crossref
L Good, E Peterson & B Lisander. (2003) Tranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement. British Journal of Anaesthesia 90:5, pages 596-599.
Crossref
Crossref
T. Kovesi & D. Royston. (2003) Pharmacological approaches to reducing allogeneic blood exposure. Vox Sanguinis 84:1, pages 2-10.
Crossref
Crossref
Robert J. Porte & Frank W.G. Leebeek. (2002) Pharmacological Strategies to Decrease Transfusion Requirements in Patients Undergoing Surgery. Drugs 62:15, pages 2193-2211.
Crossref
Crossref