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Acta Orthopaedica Scandinavica Volume 73, 2002 - Issue 4
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Research Article

Effect of submicron polyethylene particles on an osseointegrated implant

Mikael Sundfeldt Departments of Biomaterials/Handicap Research, Box 412, SE-405 30 Goteborg, Sweden. E-mail: [email protected], Orthopaedics, Sahlgrenska University Hospital, Institute for Surgical Sciences, University of Gothenburg, 3Orthopaedics of Varbergs Hospital, Sweden, 4Joint Replacement Institute of Los Angeles, Orthopaedic Hospital, Los Angeles, CA, USA
,
Michael Widmark Departments of Biomaterials/Handicap Research, Box 412, SE-405 30 Goteborg, Sweden. E-mail: [email protected], Orthopaedics, Sahlgrenska University Hospital, Institute for Surgical Sciences, University of Gothenburg, 3Orthopaedics of Varbergs Hospital, Sweden, 4Joint Replacement Institute of Los Angeles, Orthopaedic Hospital, Los Angeles, CA, USA
,
Carina B Johansson Departments of Biomaterials/Handicap Research, Box 412, SE-405 30 Goteborg, Sweden. E-mail: [email protected], Orthopaedics, Sahlgrenska University Hospital, Institute for Surgical Sciences, University of Gothenburg, 3Orthopaedics of Varbergs Hospital, Sweden, 4Joint Replacement Institute of Los Angeles, Orthopaedic Hospital, Los Angeles, CA, USA
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Patricia Campbell Departments of Biomaterials/Handicap Research, Box 412, SE-405 30 Goteborg, Sweden. E-mail: [email protected], Orthopaedics, Sahlgrenska University Hospital, Institute for Surgical Sciences, University of Gothenburg, 3Orthopaedics of Varbergs Hospital, Sweden, 4Joint Replacement Institute of Los Angeles, Orthopaedic Hospital, Los Angeles, CA, USA
&
Lars V Carlsson Departments of Biomaterials/Handicap Research, Box 412, SE-405 30 Goteborg, Sweden. E-mail: [email protected], Orthopaedics, Sahlgrenska University Hospital, Institute for Surgical Sciences, University of Gothenburg, 3Orthopaedics of Varbergs Hospital, Sweden, 4Joint Replacement Institute of Los Angeles, Orthopaedic Hospital, Los Angeles, CA, USA
Pages 416-424 | Published online: 08 Jul 2009

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Mikael Sundfeldt, Lars V Carlsson, Carina B Johansson, Peter Thomsen & Christina Gretzer. (2006) Aseptic loosening, not only a question of wear: A review of different theories. Acta Orthopaedica 77:2, pages 177-197.
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Lars V Carlsson, Björn E J Albrektsson, Björn G Albrektsson, Tomas O Albrektsson, C Magnus Jacobsson, Warren Macdonald, Lars Regnér, Tord Röstlund & Lars R Weidenhielm. (2006) Stepwise introduction of a bone-conserving osseointegrated hip arthroplasty using RSA and a randomized study: I. Preliminary investigations—52 patients followed for 3 years. Acta Orthopaedica 77:4, pages 549-558.
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Noah J Epstein, William E Bragg, Ting Ma, Joshua Spanogle, R Lane Smith & Stuart B Goodman. (2005) UHMWPE wear debris upregulates mononuclear cell proinflammatory gene expression in a novel murine model of intramedullary particle disease. Acta Orthopaedica 76:3, pages 412-420.
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Articles from other publishers (24)

Bengt Mjöberg. (2023) The theory of early prosthetic loosening — a concise overview. Qeios.
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Bengt Mjöberg. (2023) The theory of early prosthetic loosening — a concise overview. Qeios.
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Bengt Mjöberg. (2022) Hip prosthetic loosening and periprosthetic osteolysis: A commentary. World Journal of Orthopedics 13:6, pages 574-577.
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Ji Lin, Carolyn M. Sofka, Constantine A. Demetracopoulos & Hollis G. Potter. (2022) The Utility of Isotropic 3D Magnetic Resonance Imaging in Assessing Painful Total Ankle Replacements. Foot & Ankle Orthopaedics 7:2, pages 247301142210948.
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Kevin C. Anderson. 2021. Primary and Revision Total Ankle Replacement. Primary and Revision Total Ankle Replacement 85 92 .
Kuo-Ti Peng, Meng-Hsueh Tsai, Chiang-Wen Lee, Yao-Chang Chiang, Pei-Chun Chen, Chun-Chieh Chen, Chih-Hsiang Chang, Hsin-Nung Shih & Pey-Jium Chang. (2018) Dysregulated expression of antioxidant enzymes in polyethylene particle-induced periprosthetic inflammation and osteolysis. PLOS ONE 13:8, pages e0202501.
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Meghan M. Moran, Brittany M. Wilson, Ryan D. Ross, Amarjit S. Virdi & Dale Rick Sumner. (2017) Arthrotomy‐based preclinical models of particle‐induced osteolysis: A systematic review. Journal of Orthopaedic Research 35:12, pages 2595-2605.
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Norman Espinosa, Georg Klammer & Stephan H. Wirth. (2017) Osteolysis in Total Ankle Replacement. Foot and Ankle Clinics 22:2, pages 267-275.
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T. Ma, J. Pajarinen, T.H. Lin & S.B. Goodman. 2017. Comprehensive Biomaterials II. Comprehensive Biomaterials II 92 105 .
Theofilos Karachalios & Antonios Koutalos. 2014. Bone-Implant Interface in Orthopedic Surgery. Bone-Implant Interface in Orthopedic Surgery 139 157 .
Jean Langlois & Moussa Hamadouche. (2010) New animal models of wear-particle osteolysis. International Orthopaedics 35:2, pages 245-251.
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T. Ma & S.B. Goodman. 2011. Comprehensive Biomaterials. Comprehensive Biomaterials 79 87 .
Eugene S. Yim, Betty Zhao, David Myung, Lampros C. Kourtis, Curtis W. Frank, Dennis Carter, Robert L. Smith & Stuart B. Goodman. (2008) Biocompatibility of poly(ethylene glycol)/poly(acrylic acid) interpenetrating polymer network hydrogel particles in RAW 264.7 macrophage and MG‐63 osteoblast cell lines. Journal of Biomedical Materials Research Part A 91A:3, pages 894-902.
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Ting Ma, Steven G. Ortiz, Zhinong Huang, Peigen Ren, R. Lane Smith & Stuart B. Goodman. (2008) In vivo murine model of continuous intramedullary infusion of particles—A preliminary study . Journal of Biomedical Materials Research Part B: Applied Biomaterials 88B:1, pages 250-253.
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Steven G. Ortiz, Ting Ma, Donald Regula, R. Lane Smith & Stuart B. Goodman. (2008) Continuous intramedullary polymer particle infusion using a murine femoral explant model. Journal of Biomedical Materials Research Part B: Applied Biomaterials 87B:2, pages 440-446.
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Ting Ma, Zhinong Huang, Pei-Gen Ren, Ryan McCally, Derek Lindsey, R.L. Smith & Stuart B. Goodman. (2008) An in vivo murine model of continuous intramedullary infusion of polyethylene particles. Biomaterials 29:27, pages 3738-3742.
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Caroline S. M. Hoenders, Marco C. Harmsen & Marja J. A. van Luyn. (2007) The local inflammatory environment and microorganisms in “aseptic” loosening of hip prostheses. Journal of Biomedical Materials Research Part B: Applied Biomaterials 86B:1, pages 291-301.
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Steven G. Ortiz, Ting Ma, Noah J. Epstein, R. Lane Smith & Stuart B. Goodman. (2007) Validation and quantification of an in vitro model of continuous infusion of submicron‐sized particles . Journal of Biomedical Materials Research Part B: Applied Biomaterials 84B:2, pages 328-333.
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Mathias Bostrom & Regis OʼKeefe. (2008) What experimental approaches (eg, in vivo, in vitro, tissue retrieval) are effective in investigating the biologic effects of particles?. Journal of the American Academy of Orthopaedic Surgeons 16, pages S63-S67.
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M. NixonG. TaylorP. Sheldon, S. J. IqbalW. Harper. (2007) Does bone quality predict loosening of cemented total hip replacements?. The Journal of Bone and Joint Surgery. British volume 89-B:10, pages 1303-1308.
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Gene R. DiResta, Holly Brown, Sean Aiken, Steven Doty, Robert Schneider, Timothy Wright & John H. Healey. (2006) Use of an absorbable membrane to position biologically inductive materials in the periprosthetic space of cemented joints. Journal of Biomechanics 39:5, pages 833-843.
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Noah J. Epstein, Bryan A. Warme, Joshua Spanogle, Ting Ma, Bill Bragg, R. Lane Smith & Stuart B. Goodman. (2005) Interleukin-1 modulates periprosthetic tissue formation in an intramedullary model of particle-induced inflammation. Journal of Orthopaedic Research 23:3, pages 501-510.
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Bryan A. Warme, Noah J. Epstein, Michael C. D. Trindade, Keita Miyanishi, Ting Ma, Ramin R. Saket, Donald Regula, Stuart B. Goodman & R. Lane Smith. (2004) Proinflammatory mediator expression in a novel murine model of titanium‐particle–induced intramedullary inflammation. Journal of Biomedical Materials Research Part B: Applied Biomaterials 71B:2, pages 360-366.
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LJ O'Hara, B Nivbrant & S Röhrl. (2016) Cross-Linked Polyethylene and Bisphosphonate Therapy for Osteolysis in Total Hip Arthroplasty: A Case Report. Journal of Orthopaedic Surgery 12:1, pages 114-121.
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