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Original Article

The mortality increase in cardiac surgery patients associated with shrunken pore syndrome correlates with the eGFRcystatin C/eGFRcreatinine-ratio

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Pages 167-173 | Received 25 Sep 2018, Accepted 16 Dec 2018, Published online: 15 Feb 2019

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Esmee C. M. Kooijmans, Helena J. H. van der Pal, Maxime C. F. Pilon, Saskia M. F. Pluijm, Margriet van der Heiden-van der Loo, Leontien C. M. Kremer, Dorine Bresters, Eline van Dulmen-den Broeder, Marry M. van den Heuvel-Eibrink, Jacqueline J. Loonen, Marloes Louwerens, Sebastian J. C. Neggers, Hanneke M. van Santen, Wim J. E. Tissing, Andrica C. H. de Vries, Gertjan J. L. Kaspers, Margreet A. Veening & Arend Bökenkamp. (2022) Shrunken pore syndrome in childhood cancer survivors treated with potentially nephrotoxic therapy. Scandinavian Journal of Clinical and Laboratory Investigation 82:7-8, pages 541-548.
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Cuixing Zhou, Yimeng Chen, Xiaozhou He & Dong Xue. (2022) The value of cystatin C in predicting perioperative and long-term prognosis of renal transplantation. Scandinavian Journal of Clinical and Laboratory Investigation 82:1, pages 1-5.
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Elisabet Söderström, Ravna Blind, Patrik Wennberg, Jonas Andersson, Stefan Söderberg, Torbjörn K. Nilsson & Johan Hultdin. (2021) Mild impairment of renal function (shrunken pore syndrome) is associated with increased risk of a future first-ever myocardial infarction in women. Scandinavian Journal of Clinical and Laboratory Investigation 81:6, pages 438-445.
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Magnus H. Jonsson, Anna Åkesson, Ami Hommel, Anders Grubb & Peter Bentzer. (2021) Markers of renal function at admission and mortality in hip fracture patients - a single center prospective observational study. Scandinavian Journal of Clinical and Laboratory Investigation 81:3, pages 201-207.
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Ichiro Yoshii & Susumu Nishiyama. (2021) The impact of shrunken pore syndrome in patient with rheumatic diseases on bone mineral metabolism. Scandinavian Journal of Clinical and Laboratory Investigation 81:1, pages 72-81.
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Song Jin, Jian Xu, Gan Shen & Pengying Gu. (2021) Predictive value of circulating cystatin C level in patients with acute coronary syndrome: a meta-analysis. Scandinavian Journal of Clinical and Laboratory Investigation 81:1, pages 1-7.
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Anna Åkesson, Veronica Lindström, Ulf Nyman, Magnus Jonsson, Magnus Abrahamson, Anders Christensson, Jonas Björk & Anders Grubb. (2020) Shrunken pore syndrome and mortality: a cohort study of patients with measured GFR and known comorbidities. Scandinavian Journal of Clinical and Laboratory Investigation 80:5, pages 412-422.
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Johan Ljungberg, Bengt Johansson, Ingvar A. Bergdahl, Anders Holmgren, Ulf Näslund, Johan Hultdin & Stefan Söderberg. (2019) Mild impairment of renal function (shrunken pore syndrome) is associated with increased risk for future surgery for aortic stenosis. Scandinavian Journal of Clinical and Laboratory Investigation 79:7, pages 524-530.
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Ruming Shen, Zhongjiao Xu, Li Lin, Jiayi Shen, Wuming Hu, Lingchun Lv & Tiemin Wei. (2024) Association between adequate dietary protein and all-cause and cardiovascular mortality in patients with selective glomerular hypofiltration syndrome. Food & Function 15:5, pages 2433-2442.
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Daijun He, Bixia Gao, Jinwei Wang, Chao Yang, Shouling Wu, Shuohua Chen, Junjuan Li, Min Chen, Ming-Hui Zhao & Luxia Zhang. (2024) Diabetes mellitus: association of cystatin C versus creatinine-based estimated glomerular filtration rate with mortality and cardiovascular events. Nephrology Dialysis Transplantation.
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Mathilde Roussel, Justine Bacchetta, Anne Laure Sellier‐Leclerc, Sandrine Lemoine, Aurélie De Mul & Laurence Derain Dubourg. (2023) Is shrunken pore syndrome also a reality in children?. Journal of Internal Medicine 295:2, pages 253-258.
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Borja Quiroga, Alberto Ortiz & Javier Díez. (2024) Selective glomerular hypofiltration syndrome. Nephrology Dialysis Transplantation 39:1, pages 10-17.
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Juan-Jesús Carrero, Edouard L. Fu, Yingying Sang, Shoshana Ballew, Marie Evans, Carl-Gustaf Elinder, Peter Barany, Lesley A. Inker, Andrew S. Levey, Josef Coresh & Morgan E. Grams. (2023) Discordances Between Creatinine- and Cystatin C–Based Estimated GFR and Adverse Clinical Outcomes in Routine Clinical Practice. American Journal of Kidney Diseases 82:5, pages 534-542.
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Yeli Wang, Ogechi M. Adingwupu, Michael G. Shlipak, Alessandro Doria, Michelle M. Estrella, Marc Froissart, Vilmundur Gudnason, Anders Grubb, Roberto Kalil, Michael Mauer, Peter Rossing, Jesse Seegmiller, Josef Coresh, Andrew S. Levey & Lesley A. Inker. (2023) Discordance Between Creatinine-Based and Cystatin C–Based Estimated GFR: Interpretation According to Performance Compared to Measured GFR. Kidney Medicine 5:10, pages 100710.
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Lauris Avotins, Juta Kroica, Aivars Petersons, Dace Zentina, Zaiga Kravale, Anna Saulite & Karlis Racenis. (2023) eGFRcystatinC/eGFRcreatinine ratio < 0.6 in patients with SARS-CoV-2 pneumonia: a prospective cohort study. BMC Nephrology 24:1.
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Ah Reum Khang, Min Jin Lee, Dongwon Yi & Yang Ho Kang. (2023) The Ratio of Estimated Glomerular Filtration Rate Based on Cystatin C and Creatinine Reflecting Cardiovascular Risk in Diabetic Patients. Diabetes & Metabolism Journal 47:3, pages 415-425.
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Linnea Malmgren, Carl Öberg, Emil den Bakker, Felicia Leion, Joanna Siódmiak, Anna Åkesson, Veronica Lindström, Erik Herou, Alain Dardashti, Liana Xhakollari, Gabriel Grubb, Helena Strevens, Magnus Abrahamson, Johanna Helmersson‐Karlqvist, Martin Magnusson, Jonas Björk, Ulf Nyman, Johan Ärnlöv, Peter Ridefelt, Torbjörn Åkerfeldt, Magnus Hansson, Anna Sjöström, Johan Mårtensson, Yoshihisa Itoh, David Grubb, Olav Tenstad, Lars‐Olov Hansson, Isleifur Olafsson, Araceli Jarquin Campos, Martin Risch, Lorenz Risch, Anders Larsson, Gunnar Nordin, Hans Pottel, Anders Christensson, Henrik Bjursten, Arend Bökenkamp & Anders Grubb. (2022) The complexity of kidney disease and diagnosing it – cystatin C, selective glomerular hypofiltration syndromes and proteome regulation. Journal of Internal Medicine 293:3, pages 293-308.
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Anders O. Larsson, Michael Hultström, Robert Frithiof, Miklos Lipcsey & Mats B. Eriksson. (2022) Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19. International Journal of Molecular Sciences 23:24, pages 15687.
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Erik Linné, Alma Elfström, Anna Åkesson, Jane Fisher, Anders Grubb, Ville Pettilä, Suvi T. Vaara, Adam Linder & Peter Bentzer. (2022) Cystatin C and derived measures of renal function as risk factors for mortality and acute kidney injury in sepsis – A post-hoc analysis of the FINNAKI cohort. Journal of Critical Care 72, pages 154148.
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Erik Herou, Anders Grubb, Alain Dardashti, Shahab Nozohoor, Igor Zindovic, Per Ederoth & Henrik Bjursten. (2022) Reduced renal elimination of larger molecules is a strong predictor for mortality. Scientific Reports 12:1.
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Chan‐Young Jung, Hyung Woo Kim, Seung Hyeok Han, Tae‐Hyun Yoo, Shin‐Wook Kang & Jung Tak Park. (2022) Creatinine–cystatin C ratio and mortality in cancer patients: a retrospective cohort study. Journal of Cachexia, Sarcopenia and Muscle 13:4, pages 2064-2072.
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Zhongcai Wu, Le Wang, Yueqiang Li, Ying Yao & Rui Zeng. (2022) Shrunken Pore Syndrome Is Associated with Renal Function Decline in Female Patients with Kidney Diseases. BioMed Research International 2022, pages 1-11.
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Agnė Laučytė-Cibulskienė, Ali-Reza Biglarnia, Carin Wallquist & Anders Christensson. (2022) Updated Pathways in Cardiorenal Continuum after Kidney Transplantation. Transplantology 3:2, pages 156-168.
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Linnea Malmgren, Fiona E. McGuigan, Anders Christensson & Kristina E. Akesson. (2022) Impaired selective renal filtration captured by eGFRcysC/eGFRcrea ratio is associated with mortality in a population based cohort of older women. Scientific Reports 12:1.
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Hyoungnae Kim, Jung Tak Park, Joongyub Lee, Ji Yong Jung, Kyu-Beck Lee, Yeong-Hoon Kim, Tae-Hyun Yoo, Shin-Wook Kang, Kyu Hun Choi, Kook-Hwan Oh, Curie Ahn & Seung Hyeok Han. (2021) The difference between cystatin C- and creatinine-based eGFR is associated with adverse cardiovascular outcome in patients with chronic kidney disease. Atherosclerosis 335, pages 53-61.
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Liana Xhakollari, Anders Grubb, Amra Jujic, Erasmus Bachus, Peter M. Nilsson, Margret Leosdottir, Anders Christensson & Martin Magnusson. (2021) The Shrunken pore syndrome is associated with poor prognosis and lower quality of life in heart failure patients: the HARVEST‐Malmö study. ESC Heart Failure 8:5, pages 3577-3586.
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Liana Xhakollari, Amra Jujic, John Molvin, Peter Nilsson, Hannes Holm, Erasmus Bachus, Margret Leosdottir, Anders Grubb, Anders Christensson & Martin Magnusson. (2021) Proteins linked to atherosclerosis and cell proliferation are associated with the shrunken pore syndrome in heart failure patients. PROTEOMICS – Clinical Applications 15:4.
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Anders Grubb. (2020) Shrunken pore syndrome - a common kidney disorder with high mortality. Diagnosis, prevalence, pathophysiology and treatment options. Clinical Biochemistry 83, pages 12-20.
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Magnus Hansson, Rasmus Gustafsson, Chloé Jacquet, Nedia Chebaane, Simon Satchell, Therese Thunberg, Clas Ahlm & Anne-Marie Fors Connolly. (2020) Cystatin C and α-1-Microglobulin Predict Severe Acute Kidney Injury in Patients with Hemorrhagic Fever with Renal Syndrome. Pathogens 9:8, pages 666.
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Hua Zhou, Min Yang, Xiaozhou He & Ning Xu. (2019) eGFR, cystatin C and creatinine in shrunken pore syndrome. Clinica Chimica Acta 498, pages 1-5.
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