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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 13
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Original Articles

Thiamine Hydrochloride–Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions

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Pages 1969-1976 | Received 02 Feb 2010, Published online: 02 May 2011

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Mohd Danish Ansari, Hozeyfa Sagir, Vijay B. Yadav, Ankit Verma, Mohd Nazeef, Sonam Shakya & I. R. Siddiqui. (2023) DFT Analysis and Synthesis of Medicinally Important Pyrrolo[2,3-d]Pyrimidines by Using Thiamine Hydrochloride as a Recyclable Organocatalyst in Aqueous Media. Polycyclic Aromatic Compounds 43:8, pages 7531-7546.
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Sandeep Singh, Annah Gupta & Kamal K. Kapoor. (2020) Facile one-pot multicomponent synthesis of highly functionalized tetrahydropyridines using thiamine hydrochloride as an organocatalyst. Synthetic Communications 50:7, pages 1056-1063.
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Shahin Fatma, Preyas Ankit, Mandavi Singh, Shyam Babu Singh & Jagdamba Singh. (2014) Nucleophilic, Heterocyclic, Carbene-Catalyzed, Solvent-Free, One-Pot Synthesis of Polyhydroquinolines via Multicomponent Hantzsch Reaction: An Efficient and Ecofriendly Approach. Synthetic Communications 44:12, pages 1810-1816.
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Articles from other publishers (28)

Tran Quang Hung, Ban Van Phuc, Pham Thị Thanh Loan, Do Thi Lan Nhi, Hien NguyenHoan Xuan Vu, Dang Van Do & Tuan Thanh Dang. (2023) Practical Synthesis of 1,4-Dihydropyridines on Heterogeneous Sulfonicmodified Silica (SBA-15-SO3H) Catalyst Under Mild Condition. Current Organic Synthesis 20:8, pages 880-889.
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Brenno A. D. Neto, Pedro S. Beck, Jenny E. P. Sorto & Marcos N. Eberlin. (2022) In Melting Points We Trust: A Review on the Misguiding Characterization of Multicomponent Reactions Adducts and Intermediates. Molecules 27:21, pages 7552.
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Ning Zhang, Xue Yu & Yuewei Zhang. (2022) Recent Advances of Thiamine in Organic Synthesis. Advanced Synthesis & Catalysis 364:12, pages 1914-1933.
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Svetlana O. Kushch, Marina V. Goryaeva, Elena A. Surnina, Yanina V. Burgart, Marina A. Ezhikova, Mikhail I. Kodess, Pavel A. Slepukhin & Victor I. Saloutin. (2021) Multicomponent Domino Reactions for the Synthesis of Variable Hydrogenated Imidazo[1,2‐ a ]pyridines . Asian Journal of Organic Chemistry 11:2.
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Nahda Zafira, Dewi Septianingtyas, Zulhipri, Fera Kurniadewi & Hanhan Dianhar. A simple synthesis of Hantzsch esters derivatives as proton donors in the hydrogenation transfer reaction. A simple synthesis of Hantzsch esters derivatives as proton donors in the hydrogenation transfer reaction.
Marina V. Goryaeva, Svetlana O. Kushch, Olga G. Khudina, Yanina V. Burgart, Marina A. Ezhikova, Mikhail I. Kodess, Pavel A. Slepukhin, Alexandrina S. Volobueva, Alexander V. Slita, Iana L. Esaulkova, Maria A. Misiurina, Vladimir V. Zarubaev & Victor I. Saloutin. (2021) New multicomponent approach to polyfluoroalkylated pyrido[1,2-a]pyrimidine derivatives and bis-cyclohexenones. Journal of Fluorine Chemistry 241, pages 109686.
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Sivagami Mathavan & Rajesh B. R. D. Yamajala. (2020) Sustainable Synthetic Approaches for 3‐Aminoimidazo‐fused Heterocycles via Groebke‐Blackburn‐Bienaymé Process . ChemistrySelect 5:34, pages 10637-10642.
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Amna M. Abdella, Amr M. Abdelmoniem, Ismail A. Abdelhamid & Ahmed H. M. Elwahy. (2020) Synthesis of heterocyclic compounds via Michael and Hantzsch reactions. Journal of Heterocyclic Chemistry 57:4, pages 1476-1523.
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Mohammad Ali Bodaghifard. (2019) Organic base grafted on magnetic nanoparticles as a recoverable catalyst for the green synthesis of hydropyridine rings. Journal of the Iranian Chemical Society 17:2, pages 483-492.
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Madhushree Das Sarma & Subhojit Ghosh. (2020) Recent Advances in Catalysis of Hantzsch and Related Synthesis of 1,4-Dihydropyridines and Polyhydroquinolines: A Brief Overview. Asian Journal of Chemistry 32:12, pages 2943-2952.
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Sivagami Mathavan, Keerthana Kannan & Rajesh B. R. D. Yamajala. (2019) Thiamine hydrochloride as a recyclable organocatalyst for the synthesis of bis(indolyl)methanes, tris(indolyl)methanes, 3,3-di(indol-3-yl)indolin-2-ones and biscoumarins. Organic & Biomolecular Chemistry 17:44, pages 9620-9626.
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Fatemeh Rafiee & Nasrin Mehdizadeh. (2018) Palladium N-Heterocyclic Carbene Complex of Vitamin B1 Supported on Silica-Coated Fe3O4 Nanoparticles: A Green and Efficient Catalyst for C–C Coupling. Catalysis Letters 148:5, pages 1345-1354.
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Larry Yet. 2018. Privileged Structures in Drug Discovery. Privileged Structures in Drug Discovery 59 82 .
Vyacheslav E. Saraev, Ievgen M. Zviagin, Rafael G. Melik‐Oganjanyan, Yulia V. Sen'ko, Sergey M. Desenko & Valentin A. Chebanov. (2015) Green Microwave‐assisted Multicomponent Route to the Formation of 5,8‐Dihydropyrido[2,3‐ d ]pyrimidine Skeleton in Aqueous Media . Journal of Heterocyclic Chemistry 54:1, pages 318-324.
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Amol U. Khandebharad, Swapnil R. Sarda, Charansingh H. Gill, Mahesh G. Soni & Brijmohan R. Agrawal. (2016) Condition based divergence in synthesis of tetrahydrobenzo[b]pyrans. Research on Chemical Intermediates 42:6, pages 5779-5787.
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Ridaphun Nongrum, Geetmani Singh Nongthombam, Mattilang Kharkongor, Jims World Star Rani, Noimur Rahman, Chingrishon Kathing, Bekington Myrboh & Rishanlang Nongkhlaw. (2016) A nano-organo catalyzed route towards the efficient synthesis of benzo[b]pyran derivatives under ultrasonic irradiation. RSC Advances 6:110, pages 108384-108392.
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Daniel Könning & Jörg Swatschek. 2015. Multicomponent Reactions. Multicomponent Reactions 416 495 .
Pankaj Sharma & Monika Gupta. (2015) Silica functionalized sulphonic acid coated with ionic liquid: an efficient and recyclable heterogeneous catalyst for the one-pot synthesis of 1,4-dihydropyridines under solvent-free conditions. Green Chemistry 17:2, pages 1100-1106.
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Shahin Fatma, Divya Singh, Priya Mishra, Pravin K. Singh, Preyas Ankit & J. Singh. (2019) Novel, Versatile and Eco-Compatible Preparation of new 6-(1 H -indol-3-yl)-2-oxo-4-aryl-1,2,3,4-tetrahydropyrimidine-5-carbonitriles in water . Journal of Chemical Research 37:10, pages 642-644.
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Valmik D. Dhakane, Somnath S. Gholap, Umesh P. Deshmukh, Hemant V. Chavan & Babasaheb P. Bandgar. (2013) An efficient and green method for the synthesis of [1,3]oxazine derivatives catalyzed by thiamine hydrochloride (VB1) in water. Comptes Rendus. Chimie 17:5, pages 431-436.
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Fanglei Chen, Min Lei & Lihong Hu. (2013) Thiamine hydrochloride (VB1)-catalyzed one-pot synthesis of (E)-N-benzylidene-2-phenyl-1H-benzo[d]imidazo[1,2-a]imidazol-3-amine derivatives. Tetrahedron 69:14, pages 2954-2960.
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I. R. Siddiqui, Pragati Rai, Rahila, Anushree Srivastava, Arjita Srivastava & Anjali Srivastava. (2013) Synthesis of fused pyridines in the presence of thiamine hydrochloride as an efficient and reusable catalyst in aqueous conditions. New Journal of Chemistry 37:11, pages 3798.
Crossref
Shahin Fatma, Divya Singh, Priya Mishra, Pravin K. Singh, Preyas Ankit, Mandavi Singh & J. Singh. (2013) Nucleophilic heterocyclic carbene promoted one pot multicomponent synthesis of new 6-(1H-indol-3-yl)-2-oxo-4-aryl-1,2,3,4 tetrahydropyrimidine-5-carbonitriles: an eco-compatible approach with PEG as a biodegradable medium. RSC Adv. 3:44, pages 22527-22531.
Crossref
Yijia Chen, Weiguang Shan, Min Lei & Lihong Hu. (2012) Thiamine hydrochloride (VB1) as an efficient promoter for the one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones. Tetrahedron Letters 53:44, pages 5923-5925.
Crossref
Koyel Pradhan, Pranabes Bhattacharyya, Sanjay Paul & Asish R. Das. (2012) Synthesis of 3,4-dihydropyridin-2-one derivatives in convergent mode applying bio catalyst vitamin B1 and polymer supported catalyst PEG–SO3H from two different sets of building blocks. Tetrahedron Letters 53:44, pages 5840-5844.
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JEMIN R AVALANI, DEVJI S PATEL & DIPAK K RAVAL. (2012) 1-Methylimidazolium trifluoroacetate [Hmim]Tfa: Mild and efficient Brønsted acidic ionic liquid for Hantzsch reaction under microwave irradiation. Journal of Chemical Sciences 124:5, pages 1091-1096.
Crossref
Min Lei, Lei Ma & Lihong Hu. (2011) ChemInform Abstract: Thiamine Hydrochloride‐Catalyzed One‐Pot Synthesis of 1,4‐Dihydropyridine Derivatives under Solvent‐Free Conditions.. ChemInform 43:1.
Crossref
Junhua Liu, Min Lei & Lihong Hu. (2012) Thiamine hydrochloride (VB1): an efficient promoter for the one-pot synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine and [1,2,4]triazolo[1,5-a]pyrimidine derivatives in water medium. Green Chemistry 14:3, pages 840.
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