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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 1
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Research Article

Cytochrome P450-dependent metabolism of gefitinib

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Pages 39-50 | Received 25 Aug 2004, Published online: 22 Sep 2008

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Billy J. Molloy, Adam King, Lauren G. Mullin, Lee A. Gethings, Robert Riley, Robert S. Plumb & Ian D. Wilson. (2021) Rapid determination of the pharmacokinetics and metabolic fate of gefitinib in the mouse using a combination of UPLC/MS/MS, UPLC/QToF/MS, and ion mobility (IM)-enabled UPLC/QToF/MS. Xenobiotica 51:4, pages 434-446.
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Ping Fang, Xiang Zheng, Jiayang He, Honglei Ge, Pengfei Tang, Jianping Cai & Guoxin Hu. (2017) Functional characterization of wild-type and 24 CYP2D6 allelic variants on gefitinib metabolism in vitro. Drug Design, Development and Therapy 11, pages 1283-1290.
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M Tiseo, M Bartolotti, F Gelsomino & P Bordi. (2010) Emerging role of gefitinib in the treatment of non-small-cell lung cancer (NSCLC). Drug Design, Development and Therapy 4, pages 81-98.
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Lynn Campbell, Fiona Blackhall & Nicholas Thatcher. (2010) Gefitinib for the treatment of non-small-cell lung cancer. Expert Opinion on Pharmacotherapy 11:8, pages 1343-1357.
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Toyoaki Hida, Shizu Ogawa, Jang Chul Park, Ji Young Park, Junichi Shimizu, Yoshitsugu Horio & Kimihide Yoshida. (2009) Gefitinib for the treatment of non-small-cell lung cancer. Expert Review of Anticancer Therapy 9:1, pages 17-35.
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