Citations (25)
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Urban Fagerholm, Sven Hellberg, Jonathan Alvarsson, Staffan Arvidsson McShane & Ola Spjuth. (2021) In silico prediction of volume of distribution of drugs in man using conformal prediction performs on par with animal data-based models. Xenobiotica 51:12, pages 1366-1371.
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Urban Fagerholm, Ola Spjuth & Sven Hellberg. (2021) Comparison between lab variability and in silico prediction errors for the unbound fraction of drugs in human plasma. Xenobiotica 51:10, pages 1095-1100.
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Jaydeep Yadav, Mehdi El Hassani, Jasleen Sodhi, Volker M. Lauschke, Jessica H. Hartman & Laura E. Russell. (2021) Recent developments in in vitro and in vivo models for improved translation of preclinical pharmacokinetics and pharmacodynamics data. Drug Metabolism Reviews 53:2, pages 207-233.
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Adam J. Lucas, Joanne L. Sproston, Patrick Barton & Robert J. Riley. (2019) Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery. Expert Opinion on Drug Discovery 14:12, pages 1313-1327.
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Ugo Zanelli, Thomas Michna & Carl Petersson. (2019) Determination of low intrinsic clearance in vitro: the benefit of a novel internal standard in human hepatocyte incubations. Xenobiotica 49:4, pages 381-387.
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Floriane Lignet, Christina Esdar, Gina Walter-Bausch, Manja Friese-Hamim, Sofia Stinchi, Elise Drouin, Samer El Bawab, Andreas D. Becker, Claude Gimmi, Michael P. Sanderson & Felix Rohdich. (2023) Translational PK/PD Modeling of Tumor Growth Inhibition and Target Inhibition to Support Dose Range Selection of the LMP7 Inhibitor M3258 in Relapsed/Refractory Multiple Myeloma. Journal of Pharmacology and Experimental Therapeutics 384:1, pages 163-172.
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Urban Fagerholm, Ola Spjuth & Sven Hellberg. (2022) The Impact of Reference Data Selection for the Prediction Accuracy of Intrinsic Hepatic Metabolic Clearance. Journal of Pharmaceutical Sciences 111:9, pages 2645-2649.
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