Comparison of methods for the prediction of human clearance from hepatocyte intrinsic clearance for a set of reference compounds and an external evaluation set

Tetsuo YamagataGlobal Early Development/Quantitative Pharmacology and Drug Disposition (QPD), Merck KGaA, Grafing, Germany and

Ugo ZanelliGlobal Early Development/Quantitative Pharmacology and Drug Disposition (QPD), Merck KGaA, Darmstadt, Germany

Dieter GallemannGlobal Early Development/Quantitative Pharmacology and Drug Disposition (QPD), Merck KGaA, Grafing, Germany and

Dominique PerrinGlobal Early Development/Quantitative Pharmacology and Drug Disposition (QPD), Merck KGaA, Darmstadt, Germany

Hugues DolgosGlobal Early Development/Quantitative Pharmacology and Drug Disposition (QPD), Merck KGaA, Darmstadt, Germany

Carl PeterssonGlobal Early Development/Quantitative Pharmacology and Drug Disposition (QPD), Merck KGaA, Darmstadt, GermanyCorrespondence[email protected]

Comparison of methods for the prediction of human clearance from hepatocyte intrinsic clearance for a set of reference compounds and an external evaluation set

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Comparison of methods for the prediction of human clearance from hepatocyte intrinsic clearance for a set of reference compounds and an external evaluation set

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