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Original

Is Caffeine Addictive?—A Review of the Literature

, M.D.
Pages 493-502 | Published online: 07 Jul 2009

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Shalini Srivastava, Mark Mennemeier & Surekha Pimple. (2017) Effect of Alpinia galanga on Mental Alertness and Sustained Attention With or Without Caffeine: A Randomized Placebo-Controlled Study. Journal of the American College of Nutrition 36:8, pages 631-639.
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James G. Phillips, Jonathan Currie & Rowan P. Ogeil. (2016) Consumption and foraging behaviors for common stimulants (nicotine, caffeine). Journal of Addictive Diseases 35:1, pages 15-21.
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Astrid Nehlig, Jean-Paul Armspach & Izzie J. Namer. (2010) SPECT assessment of brain activation induced by caffeine: no effect on areas involved in dependence. Dialogues in Clinical Neuroscience 12:2, pages 255-263.
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Eric R. Braverman, Catherine A. Dennen, Mark S. Gold, Abdalla Bowirrat, Ashim Gupta, David Baron, A. Kenison Roy, David E. Smith, Jean Lud Cadet & Kenneth Blum. (2022) Proposing a “Brain Health Checkup (BHC)” as a Global Potential “Standard of Care” to Overcome Reward Dysregulation in Primary Care Medicine: Coupling Genetic Risk Testing and Induction of “Dopamine Homeostasis”. International Journal of Environmental Research and Public Health 19:9, pages 5480.
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Gabrielle Rabelo Quadra, Emília Marques Brovini, Joyce Andreia dos Santos & José R. Paranaíba. 2022. Handbook of Substance Misuse and Addictions. Handbook of Substance Misuse and Addictions 1535 1552 .
Gabrielle Rabelo Quadra, Emília Marques Brovini, Joyce Andreia dos Santos & José R. Paranaíba. 2021. Handbook of Substance Misuse and Addictions. Handbook of Substance Misuse and Addictions 1 18 .
Kamil Rodak, Izabela Kokot & Ewa Maria Kratz. (2021) Caffeine as a Factor Influencing the Functioning of the Human Body—Friend or Foe?. Nutrients 13:9, pages 3088.
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Liliana Sofia da Silva Gache, Josiana Vaz & Juliana Almeida-de-Souza. (2021) Systematic Review of the Effects of Coffee or Its Components on Platelets and Their Regulators. Journal of Caffeine and Adenosine Research 11:3, pages 51-64.
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Andreas G. Franke, Gabriele Koller, Daniela Krause, Lisa Proebstl, Felicia Kamp, Oliver Pogarell, Tarek Jebrini, Kirsi Manz, Agnieszka I. Chrobok & Michael Soyka. (2021) Just “Like Coffee” or Neuroenhancement by Stimulants?. Frontiers in Public Health 9.
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Johann Stuby, Isaac Gravestock, Evelyn Wolfram, Giuseppe Pichierri, Johann Steurer & Jakob M. Burgstaller. (2019) Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review. Nutrients 11:9, pages 2238.
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Mohammad Bakri Alaa HammamiYazan Ghazi Al ShaikhAnas Mohamad HashemObaidah M. Mukhles AdiIhab Ahmed Aal YaseenZiad Mahmoud El MenawyAdel B. Elmoselhi. (2018) Caffeine Consumption Levels and Knowledge Among Adults in the United Arab Emirates: Insights from a Nationwide Survey. Journal of Caffeine and Adenosine Research 8:2, pages 71-79.
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Shalu Kumar, Lokesh Verma & Nishant S. Jain. (2018) Role of histamine H1 receptor in caffeine induced locomotor sensitization. Neuroscience Letters 668, pages 60-66.
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Michael Soyka & Andreas G. Franke. (2017) (Psycho-)Stimulanzien in Psychopharmakotherapie und pharmakologischem Neuroenhancement und ihre suchtmedizinischen Implikationen. SUCHT 63:3, pages 157-167.
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Britta Folmer, Adriana Farah, Lawrence Jones & Vincenzo Fogliano. 2017. The Craft and Science of Coffee. The Craft and Science of Coffee 493 520 .
Magda Dubińska-Magiera, Małgorzata Daczewska, Anna Lewicka, Marta Migocka-Patrzałek, Joanna Niedbalska-Tarnowska & Krzysztof Jagla. (2016) Zebrafish: A Model for the Study of Toxicants Affecting Muscle Development and Function. International Journal of Molecular Sciences 17:11, pages 1941.
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Luana C. Santos, Julia Ruiz-Oliveira, Jéssica J. Oliveira, Priscila F. Silva & Ana C. Luchiari. (2016) Irish coffee: Effects of alcohol and caffeine on object discrimination in zebrafish. Pharmacology Biochemistry and Behavior 143, pages 34-43.
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Travis J. McGregorJeffery C. Batis. (2016) A Novel Method for Assessing Caffeine Dependence. Journal of Caffeine Research 6:1, pages 26-33.
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Carla E. Ramacciotti, Elisabetta Coli & Annalisa Burgalassi. 2016. Chemically Modified Bodies. Chemically Modified Bodies 79 92 .
Robert N. Hughes. 2016. Neuropathology of Drug Addictions and Substance Misuse. Neuropathology of Drug Addictions and Substance Misuse 775 784 .
Wolfgang BeiglböckWolfgang Beiglböck. 2016. Koffein. Koffein 147 159 .
James G. Phillips & Rowan P. Ogeil. (2015) Decision-making style, nicotine and caffeine use and dependence. Human Psychopharmacology: Clinical and Experimental 30:6, pages 442-450.
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Andreas G. Franke, Christiana Bagusat, Carolyn McFarlane, Teresina Tassone-Steiger, Werner Kneist & Klaus Lieb. (2015) The Use of Caffeinated Substances by Surgeons for Cognitive Enhancement. Annals of Surgery 261:6, pages 1091-1095.
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Andreas G. Franke & Christiana Bagusat. 2015. Coffee in Health and Disease Prevention. Coffee in Health and Disease Prevention 721 727 .
Merideth A. Addicott. (2014) Caffeine Use Disorder: A Review of the Evidence and Future Implications. Current Addiction Reports 1:3, pages 186-192.
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Rufino S. Rodriguez, Rebecca Haugen, Alexandra Rueber & Cheng-chen Huang. (2014) Reversible neuronal and muscular toxicity of caffeine in developing vertebrates. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 163, pages 47-54.
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Karl-Uwe Petersen. (2014) Koffein in Schmerzmitteln Mär oder Medizin?Caffeine in analgesics – myth or medicine?. MMW - Fortschritte der Medizin 155:S7, pages 109-114.
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Alan J. BudneyPamela C. BrownRoland R. GriffithsJohn R. HughesLaura M. Juliano. (2013) Caffeine Withdrawal and Dependence: A Convenience Survey Among Addiction Professionals. Journal of Caffeine Research 3:2, pages 67-71.
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Xiaoou Liu & Rigoberto Lopez. (2012) Evidence of rational addiction to carbonated soft drinks?. China Agricultural Economic Review 4:3, pages 300-317.
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Andreas G. Franke, Klaus Lieb & Elisabeth Hildt. (2012) What Users Think about the Differences between Caffeine and Illicit/Prescription Stimulants for Cognitive Enhancement. PLoS ONE 7:6, pages e40047.
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Isabela Ferrari Pereira Lima, Juliano De Dea Lindner, Vanete Thomaz Soccol, José Luiz Parada & Carlos Ricardo Soccol. (2012) Development of an Innovative Nutraceutical Fermented Beverage from Herbal Mate (Ilex paraguariensis A.St.-Hil.) Extract. International Journal of Molecular Sciences 13:1, pages 788-800.
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Roberta Zancheta, Ana P.M. Possi, Cleopatra S. Planeta & Marcelo T. Marin. (2012) Repeated administration of caffeine induces either sensitization or tolerance of locomotor stimulation depending on the environmental context. Pharmacological Reports 64:1, pages 70-77.
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Catherine L.W. StrileyRoland R. GriffithsLinda B. Cottler. (2011) Evaluating Dependence Criteria for Caffeine. Journal of Caffeine Research 1:4, pages 219-225.
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Louis A. Pagliaro & Ann Marie Pagliaro. 2011. Handbook of Child and Adolescent Drug and Substance Abuse. Handbook of Child and Adolescent Drug and Substance Abuse 371 453 .
A. Sinanian, Y. Edel, G. Pirlot & D. Cupa. (2010) Clinique possible d’une addiction à la caféine à partir de l’observation de 52 sujets et d’une revue de la littérature. Annales Médico-psychologiques, revue psychiatrique 168:7, pages 495-501.
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Thierry Favrod-Coune & Barbara Broers. (2010) The Health Effect of Psychostimulants: A Literature Review. Pharmaceuticals 3:7, pages 2333-2361.
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A. Burgalassi, C. E. Ramacciotti, M. Bianchi, E. Coli, L. Polese, E. Bondi, G. Massimetti & L. Dell’Osso. (2013) Caffeine consumption among eating disorder patients: Epidemiology, motivations, and potential of abuse. Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity 14:4, pages e212-e218.
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Jennifer L. Temple. (2009) Caffeine use in children: What we know, what we have left to learn, and why we should worry. Neuroscience & Biobehavioral Reviews 33:6, pages 793-806.
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Silvia Rossi, Valentina De Chiara, Alessandra Musella, Giorgia Mataluni, Lucia Sacchetti, Alberto Siracusano, Giorgio Bernardi, Alessandro Usiello & Diego Centonze. (2009) Caffeine drinking potentiates cannabinoid transmission in the striatum: Interaction with stress effects. Neuropharmacology 56:3, pages 590-597.
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Stephen Ozsungur, Darren Brenner & Ahmed El-Sohemy. (2008) Fourteen well-described caffeine withdrawal symptoms factor into three clusters. Psychopharmacology 201:4, pages 541-548.
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Robert E. Shapiro. (2008) Caffeine and headaches. Current Pain and Headache Reports 12:4, pages 311-315.
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Raymond Niesink. 2008. Drugs en alcohol; Gebruik, misbruik en verslaving. Drugs en alcohol; Gebruik, misbruik en verslaving 279 304 .
Monicque M. Lorist & Jan Snel. 2008. Sleep and Quality of Life in Clinical Medicine. Sleep and Quality of Life in Clinical Medicine 325 332 .

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