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Comments on Inorganic Chemistry
A Journal of Critical Discussion of the Current Literature
Volume 22, 2000 - Issue 3-4
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Original Articles

Anti-Inflammatory Compounds as Ligands in Metal Complexes as Revealed in X-Ray Structural Studies

Pages 151-186 | Received 13 Dec 1999, Published online: 23 Oct 2006

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Lora Dyakova, Daniela-Cristina Culita, Tanya Zhivkova, Milena Georgieva, Reni Kalfin, George Miloshev, Marin Alexandrov, Gabriela Marinescu, Luminita Patron & Radostina Alexandrova. (2015) 3d metal complexes with meloxicam as therapeutic agents in the fight against human glioblastoma multiforme and cervical carcinoma. Biotechnology & Biotechnological Equipment 29:6, pages 1190-1200.
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Humaira Iqbal, Saqib Ali, Saira Shahzadi, Saroj K. Sharma, Kushal Qanungo & Muhammad Shahid. (2015) Synthesis and characterization of hetero-bimetallic complexes with 2-mercapto-5-methyl-benzimidazole: theoretical study and biological activities. Journal of Coordination Chemistry 68:14, pages 2434-2448.
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Nazlı Uzun, Alper Tolga Çolak, Fatih Mehmet Emen, Gorkem Kismali, Ogunc Meral, Merve Alpay, Gülbanu Koyundereli Çılgı & Ertan Şahin. (2015) The syntheses, crystal structure, thermal analysis, and anticancer activities of novel dipicolinate complexes. Journal of Coordination Chemistry 68:6, pages 949-967.
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Nadia E. A. El-Gamel. (2009) The interactions of metal ions with nonsteroidal anti-inflammatory drugs (oxicams). Journal of Coordination Chemistry 62:14, pages 2239-2260.
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Dimitra Kovala-Demertzi, Dimitra Hadjipavlou-Litina, Malgorzata Staninska, Alexandra Primikiri, Chronis Kotoglou & Mavroudis A. Demertzis. (2009) Anti-oxidant, in vitro, in vivo anti-inflammatory activity and antiproliferative activity of mefenamic acid and its metal complexes with manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II). Journal of Enzyme Inhibition and Medicinal Chemistry 24:3, pages 742-752.
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Anju Saini & Priti Bansal. (2022) Quenching Studies as Important Toolkit for Exploring Binding Propensity of Metal Complexes with Serum Albumin and DNA (A Review). Pharmaceutical Chemistry Journal 56:4, pages 545-558.
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Amani S. Alturiqi, Eida S. Al-Farraj, Murefah M. Anazy & Reda A. Ammar. (2022) Potentiometric Determination of Stability Constants of Binary and Ternary Complexes of L-Tryptophan and Anti-Inflammatory Drugs with Zn(II). International Journal of Electrochemical Science 17:5, pages 220535.
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Ali Imani, Sepehr Soleymani, Rouhollah Vahabpour, Zahra Hajimahdi & Afshin Zarghi. (2022) Piroxicam Analogs: Design, Synthesis, Docking Study and Biological Evaluation as Promising Anti-HIV-1 Agents. Medicinal Chemistry 18:2, pages 209-219.
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Eduardo L. Gutiérrez, M. Paulina Montaña & Gabriela V. Ferrari. (2019) On Piroxicam degradation by homogeneous Fenton’s reaction and the influence of iron cations complexation. Journal of Water Process Engineering 28, pages 82-87.
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Richa Arora, Upasana Issar & Rita Kakkar. (2018) Theoretical investigation of organotin(IV) complexes of substituted benzohydroxamic acids. Computational and Theoretical Chemistry 1138, pages 57-65.
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Sathi Goswami, Suhita Ray & Munna Sarkar. (2016) Spectroscopic studies on the interaction of DNA with the copper complexes of NSAIDs lornoxicam and isoxicam. International Journal of Biological Macromolecules 93, pages 47-56.
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Leila Tabrizi, Hossein Chiniforoshan & Patrick McArdle. (2015) Synthesis, crystal structure and spectroscopy of bioactive Cd(II) polymeric complex of the non-steroidal anti-inflammatory drug diclofenac sodium: Antiproliferative and biological activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 136, pages 429-436.
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George Psomas & Dimitris P. Kessissoglou. (2013) Quinolones and non-steroidal anti-inflammatory drugs interacting with copper(ii), nickel(ii), cobalt(ii) and zinc(ii): structural features, biological evaluation and perspectives. Dalton Transactions 42:18, pages 6252.
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Yong-Tao Wang, Gui-Mei Tang, Wen-Zhu Wan, Yue Wu, Ting-Cui Tian, Jin-Hua Wang, Chao He, Xi-Fa Long, Jun-Jie Wang & Seik Weng Ng. (2012) New homochiral ferroelectric supramolecular networks of complexes constructed by chiral S-naproxen ligand. CrystEngComm 14:10, pages 3802.
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Dimitra Kovala-Demertzi, Malgorzata Staninska, Isabel Garcia-Santos, Alfonso Castineiras & Mavroudis A. Demertzis. (2011) Synthesis, crystal structures and spectroscopy of meclofenamic acid and its metal complexes with manganese(II), copper(II), zinc(II) and cadmium(II). Antiproliferative and superoxide dismutase activity. Journal of Inorganic Biochemistry 105:9, pages 1187-1195.
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Jan Moncol, Dušan Mikloš, Peter Segľa, Marian Koman & Tadeusz Lis. (2008) catena -Poly[[bis[2-(2,3-dimethylanilino)benzoato-κ O ]cadmium(II)]-di-μ-3-pyridylmethanol-κ 2 N : O ;κ 2 O : N ] . Acta Crystallographica Section E Structure Reports Online 64:3, pages m440-m441.
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Renzo Cini, Gabriella Tamasi, Sandra Defazio & Michael B. Hursthouse. (2007) Unusual coordinating behavior by three non-steroidal anti-inflammatory drugs from the oxicam family towards copper(II). Synthesis, X-ray structure for copper(II)–isoxicam, –meloxicam and –cinnoxicam-derivative complexes, and cytotoxic activity for a copper(II)–piroxicam complex. Journal of Inorganic Biochemistry 101:8, pages 1140-1152.
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Gehad G. Mohamed. (2005) Structural and thermal characterization of ternary complexes of piroxicam and alanine with transition metals: Uranyl binary and ternary complexes of piroxicam. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 62:4-5, pages 1165-1171.
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D. Kovala-Demertzi, D. Skrzypek, B. Szymańska, A. Galani & M.A. Demertzis. (2005) EPR spectroscopic study of a dinuclear copper(II) complex of tolfenamic acid. Inorganica Chimica Acta 358:1, pages 186-190.
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I. Kyrikou, S.K. Hadjikakou, D. Kovala-Demertzi, K. Viras & T. Mavromoustakos. (2004) Effects of non-steroid anti-inflammatory drugs in membrane bilayers. Chemistry and Physics of Lipids 132:2, pages 157-169.
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Nikolaos Kourkoumelis, Mavroudis A. Demertzis, Dimitra Kovala-Demertzi, Aglaia Koutsodimou & Alice Moukarika. (2004) Preparations and spectroscopic studies of organotin complexes of diclofenac. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 60:10, pages 2253-2259.
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Sandra Defazio & Renzo Cini. (2003) Synthesis, X-ray structural characterization and solution studies of metal complexes containing the anti-inflammatory drugs meloxicam and tenoxicam. Polyhedron 22:10, pages 1355-1366.
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Sandra Defazio & Renzo Cini. (2002) Synthesis, X-ray structure and molecular modelling analysis of cobalt(ii), nickel(ii), zinc(ii) and cadmium(ii) complexes of the widely used anti-inflammatory drug meloxicam. Journal of the Chemical Society, Dalton Transactions:9, pages 1888.
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