Advanced search
Publication Cover
Acta Oncologica Volume 59, 2020 - Issue 12
Journal homepage
3,001
Views
26
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLES: CANCER DIAGNOSTICS AND PROGNOSTICS

Voluntary wheel running can lead to modulation of immune checkpoint molecule expression

Marie Lund Baya The Centre for Physical Activity Research (CFAS) and Centre of Inflammation and Metabolism (CIM), Copenhagen University Hospital, 7641, University of Copenhagen, Copenhagen, DenmarkView further author information
,
Nicole Unterrainera The Centre for Physical Activity Research (CFAS) and Centre of Inflammation and Metabolism (CIM), Copenhagen University Hospital, 7641, University of Copenhagen, Copenhagen, DenmarkView further author information
,
Rikke Stagaarda The Centre for Physical Activity Research (CFAS) and Centre of Inflammation and Metabolism (CIM), Copenhagen University Hospital, 7641, University of Copenhagen, Copenhagen, DenmarkView further author information
,
Katrine Seide Pedersena The Centre for Physical Activity Research (CFAS) and Centre of Inflammation and Metabolism (CIM), Copenhagen University Hospital, 7641, University of Copenhagen, Copenhagen, DenmarkView further author information
,
Tim Schauera The Centre for Physical Activity Research (CFAS) and Centre of Inflammation and Metabolism (CIM), Copenhagen University Hospital, 7641, University of Copenhagen, Copenhagen, DenmarkView further author information
,
Mie Marienhof Staffeldtb Department of Oncology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev, DenmarkView further author information
,
Jesper Frank Christensena The Centre for Physical Activity Research (CFAS) and Centre of Inflammation and Metabolism (CIM), Copenhagen University Hospital, 7641, University of Copenhagen, Copenhagen, DenmarkView further author information
,
Pernille Hojmana The Centre for Physical Activity Research (CFAS) and Centre of Inflammation and Metabolism (CIM), Copenhagen University Hospital, 7641, University of Copenhagen, Copenhagen, DenmarkView further author information
,
Bente Klarlund Pedersena The Centre for Physical Activity Research (CFAS) and Centre of Inflammation and Metabolism (CIM), Copenhagen University Hospital, 7641, University of Copenhagen, Copenhagen, DenmarkView further author information
&
Julie Gehlc Center for Experimental Drug and Gene Electrotransfer (C*EDGE), Department of Oncology and Palliative Care, Zealand University Hospital, Roskilde, Denmark;d Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DenmarkCorrespondence[email protected]
View further author information
 show all
Pages 1447-1454 | Received 13 Mar 2020, Accepted 25 Aug 2020, Published online: 16 Sep 2020

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (10)

Trevor S. Anderson, Amanda L. McCormick, Elizabeth A. Daugherity, Mariam Oladejo, Izuchukwu F. Okpalanwaka, Savanna L. Smith, Duke Appiah, Laurence M. Wood & Devin B. Lowe. (2023) Listeria-based vaccination against the pericyte antigen RGS5 elicits anti-vascular effects and colon cancer protection. OncoImmunology 12:1.
Read now
Sandra Martinez-Morilla, Myrto Moutafi, Aileen I. Fernandez, Shlomit Jessel, Prajan Divakar, Pok Fai Wong, Rolando Garcia-Milian, Kurt A. Schalper, Harriet M. Kluger & David L. Rimm. (2023) Digital spatial profiling of melanoma shows CD95 expression in immune cells is associated with resistance to immunotherapy. OncoImmunology 12:1.
Read now
Maximilian Boesch, Florent Baty, Frank Rassouli, Tobias Kowatsch, Markus Joerger, Martin Früh & Martin H. Brutsche. (2023) Non-pharmaceutical interventions to optimize cancer immunotherapy. OncoImmunology 12:1.
Read now
Hayat Bähr-Mahmud, Ursula Ellinghaus, Christiane R. Stadler, Leyla Fischer, Claudia Lindemann, Anuhar Chaturvedi, Jan Diekmann, Stefan Wöll, Imke Biermann, Bernhard Hebich, Caroline Scharf, Manuela Siefke, Alexandra S. Roth, Martin Rao, Kerstin Brettschneider, Eva-Maria Ewen, Uğur Şahin & Özlem Türeci. (2023) Preclinical characterization of an mRNA-encoded anti-Claudin 18.2 antibody. OncoImmunology 12:1.
Read now
Alisa Lepper, Rebekka Bitsch, Feyza Gül Özbay Kurt, Ihor Arkhypov, Samantha Lasser, Jochen Utikal & Viktor Umansky. (2023) Melanoma patients with immune-related adverse events after immune checkpoint inhibitors are characterized by a distinct immunological phenotype of circulating T cells and M-MDSCs. OncoImmunology 12:1.
Read now
Naisheng Zheng, Tingting Wang, Qin Luo, Yi Liu, Junyao Yang, Yunlan Zhou, Guohua Xie, Yanhui Ma, Xiangliang Yuan & Lisong Shen. (2023) M2 macrophage-derived exosomes suppress tumor intrinsic immunogenicity to confer immunotherapy resistance. OncoImmunology 12:1.
Read now
Azar Rezapour, Daniel Rydbeck, Fabian Byvald, Viktor Tasselius, Gustaf Danielsson, Eva Angenete & Ulf Yrlid. (2023) A type I interferon footprint in pre-operative biopsies is an independent biomarker that in combination with CD8+ T cell quantification can improve the prediction of response to neoadjuvant treatment of rectal adenocarcinoma. OncoImmunology 12:1.
Read now
David Dora, Balazs Ligeti, Tamas Kovacs, Peter Revisnyei, Gabriella Galffy, Edit Dulka, Dániel Krizsán, Regina Kalcsevszki, Zsolt Megyesfalvi, Balazs Dome, Glen J. Weiss & Zoltan Lohinai. (2023) Non-small cell lung cancer patients treated with Anti-PD1 immunotherapy show distinct microbial signatures and metabolic pathways according to progression-free survival and PD-L1 status. OncoImmunology 12:1.
Read now
Zi-Hao Wang, Pei Zhang, Wen-Bei Peng, Lin-Lin Ye, Xuan Xiang, Xiao-Shan Wei, Yi-Ran Niu, Si-Yu Zhang, Qian-Qian Xue, Hao-Lei Wang & Qiong Zhou. (2023) Altered phenotypic and metabolic characteristics of FOXP3+CD3+CD56+ natural killer T (NKT)-like cells in human malignant pleural effusion. OncoImmunology 12:1.
Read now
Bao-Tram Thi Tran, Aurore Gelin, Sylvère Durand, Matthieu Texier, Amaury Daste, Clémence Toullec, Karim Benihoud, Ingrid Breuskin, Philippe Gorphe, Florence Garic, Catherine Brenner, Christophe Le Tourneau, Jérôme Fayette, Toshiro Niki, Muriel David, Pierre Busson & Caroline Even. (2023) Plasma galectins and metabolites in advanced head and neck carcinomas: evidence of distinct immune characteristics linked to hypopharyngeal tumors. OncoImmunology 12:1.
Read now

Articles from other publishers (16)

Rik J Verheijden, Anna Cabané Ballester, Karel C Smit, Mick J M van Eijs, Cheryl P Bruijnen, Anne S R van Lindert, Karijn P M Suijkerbuijk & Anne M May. (2024) Physical activity and checkpoint inhibition: association with toxicity and survival. JNCI: Journal of the National Cancer Institute 116:4, pages 573-579.
Crossref
Carmen Fiuza-Luces, Pedro L. Valenzuela, Beatriz G. Gálvez, Manuel Ramírez, Alejandro López-Soto, Richard J. Simpson & Alejandro Lucia. (2023) The effect of physical exercise on anticancer immunity. Nature Reviews Immunology 24:4, pages 282-293.
Crossref
Manon Gouez, Amélie Rébillard, Amandine Thomas, Sabine Beaumel, Eva-Laure Matera, Etienne Gouraud, Luz Orfila, Brice Martin, Olivia Pérol, Cédric Chaveroux, Erica N. Chirico, Charles Dumontet, Béatrice Fervers & Vincent Pialoux. (2024) Combined effects of exercise and immuno-chemotherapy treatments on tumor growth in MC38 colorectal cancer-bearing mice. Frontiers in Immunology 15.
Crossref
Maryam Firoozi, Alireza Barari, Asieh Abbassi Daloii & Hossein Abednatanzi. (2024) The Effect of Interval Training and Urtica Dioica Hydroalcoholic Extract on some Growth and Immune Factors in C57 Rats with Melanoma Cancer. Complementary Medicine Journal 13:4, pages 44-53.
Crossref
Amy L. Shaver, Nikita Nikita, Bach V. Tran & Felix J. Kim. 2024. Reference Module in Life Sciences. Reference Module in Life Sciences.
Huiyu Yan, Aimin Jiang, Yinong Huang, Jun Zhang, Wenguang Yang, Wei Zhang & Tianya Liu. (2023) Exercise sensitizes PD-1/PD-L1 immunotherapy as a hypoxia modulator in the tumor microenvironment of melanoma. Frontiers in Immunology 14.
Crossref
Christina Brummer, Tobias Pukrop, Joachim Wiskemann, Christina Bruss, Ines Ugele & Kathrin Renner. (2023) Can Exercise Enhance the Efficacy of Checkpoint Inhibition by Modulating Anti-Tumor Immunity?. Cancers 15:18, pages 4668.
Crossref
Harrison D. Collier-Bain, Frankie F. Brown, Adam J. Causer, Annabelle Emery, Rebecca Oliver, Sally Moore, James Murray, James E. Turner & John P. Campbell. (2023) Harnessing the immunomodulatory effects of exercise to enhance the efficacy of monoclonal antibody therapies against B-cell haematological cancers: a narrative review. Frontiers in Oncology 13.
Crossref
Jianchun Xiao, Ye Li, Treva Rowley, Jing Huang, Robert H. Yolken & Raphael P. Viscidi. (2023) Immunotherapy targeting the PD-1 pathway alleviates neuroinflammation caused by chronic Toxoplasma infection. Scientific Reports 13:1.
Crossref
C. Jongerius, L. Vermeulen, M. van Egmond, A. W. M. Evers, L. M. Buffart & K. J. Lenos. (2022) Behavioral factors to modulate immunotherapy efficacy in cancer. Frontiers in Immunology 13.
Crossref
Cécile Torregrosa, Frédéric Chorin, Eva Ester Molina Beltran, Cindy Neuzillet & Victoire Cardot-Ruffino. (2022) Physical Activity as the Best Supportive Care in Cancer: The Clinician’s and the Researcher’s Perspectives. Cancers 14:21, pages 5402.
Crossref
Jasmine Handford, Miaoqi Chen, Ridesh Rai, Charlotte L. Moss, Deborah Enting, Nicola Peat, Sophia N. Karagiannis, Mieke Van Hemelrijck & Beth Russell. (2022) Is There a Role for Exercise When Treating Patients with Cancer with Immune Checkpoint Inhibitors? A Scoping Review. Cancers 14:20, pages 5039.
Crossref
Pernille Hojman, Rikke Stagaard, Emi Adachi-Fernandez, Atul S. Deshmukh, Andreas Mund, Caroline H. Olsen, Lena Keller, Bente K. Pedersen & Julie Gehl. (2022) Exercise suppresses tumor growth independent of high fat food intake and associated immune dysfunction. Scientific Reports 12:1.
Crossref
Annabelle Emery, Sally Moore, James E. Turner & John P. Campbell. (2022) Reframing How Physical Activity Reduces The Incidence of Clinically-Diagnosed Cancers: Appraising Exercise-Induced Immuno-Modulation As An Integral Mechanism. Frontiers in Oncology 12.
Crossref
Amy L. Shaver, Swapnil Sharma, Nikita Nikita, Daniel S. Lefler, Atrayee Basu-Mallick, Jennifer M. Johnson, Meghan Butryn & Grace Lu-Yao. (2021) The Effects of Physical Activity on Cancer Patients Undergoing Treatment with Immune Checkpoint Inhibitors: A Scoping Review. Cancers 13:24, pages 6364.
Crossref
Josua Aponte Serrano & Amit Hagar. (2021) Run for your life: an integrated virtual tissue platform for incorporating exercise oncology into immunotherapy. Cancer Immunology, Immunotherapy 70:7, pages 1951-1964.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.