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Oncology

Clinical impact of a 31-gene expression profile test for cutaneous melanoma in 156 prospectively and consecutively tested patients

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Pages 1599-1604 | Received 17 Apr 2016, Accepted 18 May 2016, Published online: 03 Jun 2016

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Read on this site (11)

Gaurav Singh, Stanislav N Tolkachjov & Aaron S Farberg. (2023) Incorporation of the 40-Gene Expression Profile (40-GEP) Test to Improve Treatment Decisions in High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) Patients: Case Series and Algorithm. Clinical, Cosmetic and Investigational Dermatology 16, pages 925-935.
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Maki Yamamoto, Brenda Sickle-Santanello, Timothy Beard, Richard Essner, Brian Martin, Christine N. Bailey & J. Michael Guenther. (2023) The 31-gene expression profile test informs sentinel lymph node biopsy decisions in patients with cutaneous melanoma: results of a prospective, multicenter study. Current Medical Research and Opinion 39:3, pages 417-423.
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Perry B. Hooper, Aaron S. Farberg, Alison L. Fitzgerald, Jennifer J. Siegel, Briana B. Rackley, Anesh Prasai, Sarah J. Kurley, Matthew S. Goldberg & Graham H. Litchman. (2022) Real-World Evidence Shows Clinicians Appropriately Use the Prognostic 40-Gene Expression Profile (40-GEP) Test for High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) Patients. Cancer Investigation 40:10, pages 911-922.
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Larry D. Dillon, Michael McPhee, Robert S. Davidson, Ann P. Quick, Brian Martin, Kyle R. Covington, Olga Zolochevska, Robert W. Cook, John T. Vetto, Abel D. Jarell & Martin D. Fleming. (2022) Expanded evidence that the 31-gene expression profile test provides clinical utility for melanoma management in a multicenter study. Current Medical Research and Opinion 38:8, pages 1267-1274.
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Abel Jarell, Basil Skenderis, Larry D Dillon, Kelsey Dillon, Brian Martin, Ann P Quick, Jennifer J Siegel, Briana B Rackley & Robert W Cook. (2021) The 31-gene expression profile stratifies recurrence and metastasis risk in patients with cutaneous melanoma. Future Oncology 17:36, pages 5023-5031.
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David M Hyams, Kyle R Covington, Clare E Johnson, Kristen M Plasseraud & Robert W Cook. (2021) Integrating the Melanoma 31-Gene Expression Profile Test with Surgical Oncology Practice Within National Guideline and Staging Recommendations. Future Oncology 17:5, pages 517-527.
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Aaron S. Farberg, Mary A. Hall, Leah Douglas, Kyle R. Covington, Sarah J. Kurley, Robert W. Cook & Scott M. Dinehart. (2020) Integrating gene expression profiling into NCCN high-risk cutaneous squamous cell carcinoma management recommendations: impact on patient management. Current Medical Research and Opinion 36:8, pages 1301-1307.
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Rebecca W Knackstedt, Thomas Knackstedt & Brian Gastman. (2019) Gene Expression Profiling in Melanoma: Past Results and Future Potential. Future Oncology 15:7, pages 791-800.
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Ashley Wysong, Ally‐Khan Somani, Sherrif F. Ibrahim, Javier Cañueto, Alison L. Fitzgerald, Jennifer J. Siegel, Anesh Prasai, Matthew S. Goldberg, Aaron S. Farberg, Christie Regula, Anna Bar, Julia Kasprzak, David G. Brodland, Shlomo A. Koyfman & Sarah T. Arron. (2024) Integrating the 40-Gene Expression Profile (40-GEP) Test Improves Metastatic Risk-Stratification Within Clinically Relevant Subgroups of High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) Patients. Dermatology and Therapy 14:3, pages 593-612.
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Tiffany W Cheng, Emily Hartsough & Alessio Giubellino. (2023) Sentinel lymph node assessment in melanoma: current state and future directions. Histopathology 83:5, pages 669-684.
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Christine N. Bailey, Brian J. Martin, Valentina I. Petkov, Nicola C. Schussler, Jennifer L. Stevens, Suzanne Bentler, Rosemary D. Cress, Jennifer A. Doherty, Eric B. Durbin, Scarlett L. Gomez, Lou Gonsalves, Brenda Y. Hernandez, Lihua Liu, Bożena M. Morawski, Maria J. Schymura, Stephen M. Schwartz, Kevin C. Ward, Charles Wiggins, Xiao-Cheng Wu, Matthew S. Goldberg, Jennifer J. Siegel, Robert W. Cook, Kyle R. Covington & Sarah J. Kurley. (2023) 31-Gene Expression Profile Testing in Cutaneous Melanoma and Survival Outcomes in a Population-Based Analysis: A SEER Collaboration. JCO Precision Oncology:7.
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Bo M. Kitrell, Elliot D. Blue, Alfredo SillerJr.Jr., Marissa B. Lobl, Tyler D. Evans, Melodi Javid Whitley & Ashley Wysong. (2023) Gene Expression Profiles in Cutaneous Oncology. Dermatologic Clinics 41:1, pages 89-99.
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Kelli Ahmed, Jennifer J. Siegel, Sonia K. Morgan‐Linnell & Kyleigh LiPira. (2022) Attitudes of patients with cutaneous melanoma toward prognostic testing using the 31‐gene expression profile test. Cancer Medicine 12:2, pages 2008-2015.
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Abel Jarell, Brian R. Gastman, Larry D. Dillon, Eddy C. Hsueh, Sebastian Podlipnik, Kyle R. Covington, Robert W. Cook, Christine N. Bailey, Ann P. Quick, Brian J. Martin, Sarah J. Kurley, Matthew S. Goldberg & Susana Puig. (2022) Optimizing treatment approaches for patients with cutaneous melanoma by integrating clinical and pathologic features with the 31-gene expression profile test. Journal of the American Academy of Dermatology 87:6, pages 1312-1320.
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Aaron S. Farberg, Justin W. Marson, Alex Glazer, Graham H. Litchman, Ryan Svoboda, Richard R. Winkelmann, Nicholas Brownstone & Darrell S. Rigel. (2022) Expert Consensus on the Use of Prognostic Gene Expression Profiling Tests for the Management of Cutaneous Melanoma: Consensus from the Skin Cancer Prevention Working Group. Dermatology and Therapy 12:4, pages 807-823.
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Kevin Yang, Allen S.W. Oak, Radomir M. Slominski, Anna A. Brożyna & Andrzej T. Slominski. (2020) Current Molecular Markers of Melanoma and Treatment Targets. International Journal of Molecular Sciences 21:10, pages 3535.
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George Jour. (2020) DecisionDx‐Melanoma and Sentinel Lymph Node Biopsy: To Do or Not to Do?. Dermatologic Surgery 46:1, pages 131-131.
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Danielle P. Dubin, Scott M. Dinehart & Aaron S. Farberg. (2019) Level of Evidence Review for a Gene Expression Profile Test for Cutaneous Melanoma. American Journal of Clinical Dermatology 20:6, pages 763-770.
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S. Podlipnik, C. Carrera, A. Boada, N.A. Richarz, J.L. López‐Estebaranz, F. Pinedo‐Moraleda, M. Elosua‐González, M.M. Martín‐González, R. Carrillo‐Gijón, P. Redondo, E. Moreno, J. Malvehy & S. Puig. (2019) Early outcome of a 31‐gene expression profile test in 86 AJCC stage IB ‐ II melanoma patients. A prospective multicentre cohort study . Journal of the European Academy of Dermatology and Venereology 33:5, pages 857-862.
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Jennifer Keller, Theresa L. Schwartz, Jason M. Lizalek, Ea‐sle Chang, Ashaki D. Patel, Maria Y. Hurley & Eddy C. Hsueh. (2019) Prospective validation of the prognostic 31‐gene expression profiling test in primary cutaneous melanoma. Cancer Medicine 8:5, pages 2205-2212.
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Dirk Schadendorf, Alexander C J van Akkooi, Carola Berking, Klaus G Griewank, Ralf Gutzmer, Axel Hauschild, Andreas Stang, Alexander Roesch & Selma Ugurel. (2018) Melanoma. The Lancet 392:10151, pages 971-984.
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Laura K. Ferris, Aaron S. Farberg, Brooke Middlebrook, Clare E. Johnson, Natalie Lassen, Kristen M. Oelschlager, Derek J. Maetzold, Robert W. Cook, Darrell S. Rigel & Pedram Gerami. (2017) Identification of high-risk cutaneous melanoma tumors is improved when combining the online American Joint Committee on Cancer Individualized Melanoma Patient Outcome Prediction Tool with a 31-gene expression profile–based classification. Journal of the American Academy of Dermatology 76:5, pages 818-825.e3.
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