Advanced search
Publication Cover
Current Medical Research and Opinion Volume 34, 2018 - Issue 5: Oncology
Submit an article Journal homepage
311
Views
13
CrossRef citations to date
0
Altmetric
Hematology

Hemoglobin A2 (HbA2) has a measure of unreliability in diagnosing β-thalassemia trait (β-TT)

Amani M. Al-AmodiDepartment of Genetic Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia;
,
Neda Z. GhanemDepartment of Genetic Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia;
,
Sumayh A. AldakeelDepartment of Genetic Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia;
,
Lubna Ibrahim Al AsoomDepartment of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia;
,
Nazish Rafique AhmedDepartment of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia;
,
Noor B. AlmandilDepartment of Clinical Pharmacy Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; ORCID Iconhttp://orcid.org/0000-0002-7049-3563
ORCID Icon,
Zaki A. NaserullahDammam Maternity and Child Hospital, Dammam, Saudi Arabia;
,
Sana Al-JarrashDammam Maternity and Child Hospital, Dammam, Saudi Arabia;
,
Mohammed Shakil AkhtarDepartment of Biochemistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
,
Sayed AbdulAzeezDepartment of Genetic Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; ORCID Iconhttp://orcid.org/0000-0002-9763-9446
ORCID Icon,
Amein K. Al-AliDepartment of Biochemistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
&
J. Francis BorgioDepartment of Genetic Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; Correspondence[email protected] [email protected]
ORCID Iconhttp://orcid.org/0000-0001-7199-1540
ORCID Icon show all
Pages 945-951 | Received 18 Dec 2017, Accepted 29 Jan 2018, Published online: 15 Feb 2018

Citations (13)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Burçak Kurucu, Ali Fettah, Emre Çapkınoğlu, Nergiz Öner, Funda Eren, Özcan Erel, Şule Yeşil & Gürses Şahin. (2022) Dynamic Thiol-Disulfide Homeostasis in Children With β-Thalassemia Trait. Hemoglobin 46:3, pages 164-167.
Read now
Aisha Moeen Khan, Asma Mohammed Al-Sulaiti, Salma Younes, Mohamed Yassin & Hatem Zayed. (2021) The spectrum of beta-thalassemia mutations in the 22 Arab countries: a systematic review. Expert Review of Hematology 14:1, pages 109-122.
Read now
Anton V. Rets, Noel Scott Reading & Archana M. Agarwal. (2020) δ-Globin Chain Variants Associated with Decreased Hb A2 Levels: A National Reference Laboratory Experience . Hemoglobin 44:6, pages 438-441.
Read now

Articles from other publishers (10)

Samina Ejaz, Iqra Abdullah, Muhammad Usman, Muhammad Arslan Iqbal, Sidra Munawar, Muhammad Irfan Khan, Nagina Imtiaz, Hanniah Tahir, Muhammad Ihsan Bari, Tayyaba Rasool, Aneeza Fatima, Ramsha Anwar, Ayman Durrani & Yasir Hameed. (2023) Mutational analysis of hemoglobin genes and functional characterization of detected variants, through in-silico analysis, in Pakistani beta-thalassemia major patients. Scientific Reports 13:1.
Crossref
Keivan Moradi, Reza Alibakhshi, Samaneh Shafieenia & Azam Azimi. (2022) Problem of borderline hemoglobin A2 levels in an Iranian population with a high prevalence of α- and β-thalassemia carriers. Egyptian Journal of Medical Human Genetics 23:1.
Crossref
Priya Hariharan, Pratibha Sawant, Jayesh Sheth & Anita Nadkarni. (2022) Rapid molecular identification of a rare β-globin gene deletion & its clinical implication. Indian Journal of Medical Research 155:3, pages 432.
Crossref
Stacy Colaco & Anita Nadkarni. (2021) Borderline HbA2 levels: Dilemma in diagnosis of beta-thalassemia carriers. Mutation Research/Reviews in Mutation Research 788, pages 108387.
Crossref
Meihuan Chen, Hailong Huang, Lingji Chen, Na Lin, Min Zhang, Yuan Lin & Liangpu Xu. (2020) First report of the spectrum of δ‐globin gene mutations among women of reproductive age in Fujian area—Discrimination of δ‐thalassemia, α‐thalassemia, and Iron Deficiency Anemia. Journal of Clinical Laboratory Analysis 34:11.
Crossref
Yuan Zhou, Jibo Zhang, Chao Wang, Lihua Zhou, Lu Zhou, Dan Ou & Dan Peng. (2020) Application of HbA 2 levels and red cell indices‐based new model in the differentiation of thalassemia traits from iron deficiency in hypochromic microcytic anemia Cases . International Journal of Laboratory Hematology 42:5, pages 526-532.
Crossref
Mina Ebrahimi, Javad Mohammadi-asl & Fakher Rahim. (2020) Molecular spectrum and distribution of hemoglobinopathies in southwest of Iran: a seven-year retrospective study. Journal of Hematopathology 13:2, pages 97-103.
Crossref
Sayed AbdulAzeez, Noor B. Almandil, Zaki A. Naserullah, Sana Al-Jarrash, Ahmed M. Al-Suliman, Huda I. ElFakharay & J. Francis Borgio. (2019) Co-inheritance of alpha globin gene deletion lowering serum iron level in female beta thalassemia patients. Molecular Biology Reports 47:1, pages 603-606.
Crossref
Sayed AbdulAzeez, Nourah H. Al Qahtani, Noor B. Almandil, Amani M. Al-Amodi, Sumayh A. Aldakeel, Neda Z. Ghanem, Deem N. Alkuroud, Ameen AlTurki, Quds Abdulhakeem AlQattan, Abdulrahman Alghamdi, Norah Fahad Alhur, Hatoon Ahmed Al Taifi, Halah Egal Aljofi, B. Rabindran Jermy, Vinoth Raman, Antonino Giambona, Aurelio Maggio & J. Francis Borgio. (2019) Genetic disorder prenatal diagnosis and pregnancy termination practices among high consanguinity population, Saudi Arabia. Scientific Reports 9:1.
Crossref
Eman M. Hamed, Mohamed Hussein Meabed, Usama Farghaly Aly & Raghda R.S. Hussein. (2019) Recent Progress in Gene Therapy and Other Targeted Therapeutic Approaches for Beta Thalassemia. Current Drug Targets 20:16, pages 1603-1623.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.