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Drug Metabolism Reviews Volume 52, 2020 - Issue 3
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Review Articles

Biotransformation of arsenic trioxide by AS3MT favors eradication of acute promyelocytic leukemia: revealing the hidden facts

Yasen Maimaitiyiminga Department of Hematology of First Affiliated Hospital, and Department of Public Health, Zhejiang University School of Medicine, Hangzhou, ChinaView further author information
,
Hong-Hu Zhub Department of Hematology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaCorrespondence[email protected]
View further author information
,
Chang Yanga Department of Hematology of First Affiliated Hospital, and Department of Public Health, Zhejiang University School of Medicine, Hangzhou, ChinaView further author information
&
Hua Naranmanduraa Department of Hematology of First Affiliated Hospital, and Department of Public Health, Zhejiang University School of Medicine, Hangzhou, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0799-2340View further author information
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Pages 425-437 | Received 21 Apr 2020, Accepted 29 Jun 2020, Published online: 17 Jul 2020

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Meijuan Sui, Hong Wei, Xiaohan Shen, Keke Gao, Qian Zhang & Zhuo Zhang. (2023) Sulfhydryl compound levels are associated with ATO-induced side effects in acute promyelocytic leukemia patients. Hematology 28:1.
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Yi-zhi Jiang, Zhong-ling Wei, Na-na Wang, Chen Huang, Jun Huang, Jia-wei Yan, Ran Wang, Zheng-zhi Yu & Dong-ping Huang. (2022) Clinical characteristics of a patient with de novo acute promyelocytic leukemia with JAK2 v617f mutation. Hematology 27:1, pages 1290-1293.
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Articles from other publishers (13)

Li De Su, Hurilebater, Lu Men Chao, Sanchula, Dong Yu, Amguleng, Jian Hui Hao & Xin Li. (2024) Antipyretic and Anti-inflammatory Effects of Sanchen Pediatric Antipyretic Paste. The Natural Products Journal 14:5.
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Yichu Yang, Yiye Li, Ran Li & Zhang Wang. (2024) Research progress on arsenic, arsenic-containing medicinal materials, and arsenic-containing preparations: clinical application, pharmacological effects, and toxicity. Frontiers in Pharmacology 15.
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Liwa Shi, Jing Lu, Xin Xia, Xue Liu, Hongyan Li, Xinghua Li, Jun Zhu, Xiaofeng Li, Hongzhe Sun & Xinming Yang. (2024) Clinically used drug arsenic trioxide targets XIAP and overcomes apoptosis resistance in an organoid-based preclinical cancer model. Chemical Science.
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Jian Lv, Mengliang Wu, Chunrong Pang, Rui Duan, Hong Zhang, Shuo Tian, Haixia Yang & Xin Hai. (2023) Torsemide increases arsenic concentrations by inhibition of multidrug resistance protein 4 in arsenic trioxide treated acute promyelocytic leukemia patients. Biomedicine & Pharmacotherapy 163, pages 114858.
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Mengliang Wu, Chunrong Pang, Shengwen Lu, Thomas H. Hostetter & Xin Hai. (2023) Type 2 diabetes affects arsenic metabolism via transporters in arsenic trioxide treated acute promyelocytic leukemia patients. Environmental Toxicology and Pharmacology 100, pages 104142.
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Katarzyna M Grochowska, Guilherme M Gomes, Rajeev Raman, Rahul Kaushik, Liudmila Sosulina, Hiroshi Kaneko, Anja M Oelschlegel, PingAn Yuanxiang, Irene Reyes‐Resina, Gonca Bayraktar, Sebastian Samer, Christina Spilker, Marcel S Woo, Markus Morawski, Jürgen Goldschmidt, Manuel A Friese, Steffen Rossner, Gemma Navarro, Stefan Remy, Carsten Reissner, Anna Karpova & Michael R Kreutz. (2023) Jacob‐induced transcriptional inactivation of CREB promotes Aβ‐induced synapse loss in Alzheimer's disease . The EMBO Journal 42:4.
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Lynn Chin, Cyrus R. Kumana, Yok-Lam Kwong & Harinder Gill. (2022) The Development and Clinical Applications of Oral Arsenic Trioxide for Acute Promyelocytic Leukaemia and Other Diseases. Pharmaceutics 14:9, pages 1945.
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Yi Ming Shao, Bold Sharavyn, Ping Huang, Hua Naranmandura & Qian Qian Wang. (2022) Development of Metal-Based Drugs and Application in Clinical Treatment. The Natural Products Journal 12:3.
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Meihua Guo, Jian Lv, Xiaotong Chen, Mengliang Wu, Qilei Zhao & Xin Hai. (2022) Arsenic Trioxide Therapy During Pregnancy: ATO and Its Metabolites in Maternal Blood and Amniotic Fluid of Acute Promyelocytic Leukemia Patients. Frontiers in Oncology 12.
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Manisha Thakur, Mahesh Rachamalla, Som Niyogi, Ashok Kumar Datusalia & Swaran Jeet Singh Flora. (2021) Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions. International Journal of Molecular Sciences 22:18, pages 10077.
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Lingfang Wang, Yasen Maimaitiyiming, Kunhui Su & Chih-Hung Hsu. 2021. Epitranscriptomics. Epitranscriptomics 353 390 .
Qian Qian Wang, Hao Ying Hua, Hua Naranmandura & Hong-Hu Zhu. (2020) Balance between the toxicity and anticancer activity of arsenic trioxide in treatment of acute promyelocytic leukemia. Toxicology and Applied Pharmacology 409, pages 115299.
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Yasen Maimaitiyiming, Qian Qian Wang, Chih-Hung Hsu & Hua Naranmandura. (2020) Arsenic induced epigenetic changes and relevance to treatment of acute promyelocytic leukemia and beyond. Toxicology and Applied Pharmacology 406, pages 115212.
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