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Original Research

Effect of Dietary n-3 and n-6 Oils with and without Food Restriction on Activity of Antioxidant Enzymes and Lipid Peroxidation in Livers of Cyclophosphamide Treated Autoimmune-Prone NZB/W Female Mice

, PhD, , PhD, , MS, , MD, , MD, PhD & , PhD
Pages 388-399 | Received 09 Dec 2003, Accepted 13 May 2003, Published online: 19 Jun 2013

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Lichchavi D. Rajasinghe, Quan-Zhen Li, Chengsong Zhu, Mei Yan, Preeti S. Chauhan, Kathryn A. Wierenga, Melissa A. Bates, Jack R. Harkema, Abby D. Benninghoff & James J. Pestka. (2020) Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice. Autoimmunity 53:7, pages 415-433.
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Noriyuki Otsuki, Tasuku Konno, Toshihiro Kurahashi, Saori Suzuki, Jaeyong Lee, Futoshi Okada, Yoshihito Iuchi, Takujiro Homma & Junichi Fujii. (2016) The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice. Free Radical Research 50:7, pages 793-800.
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Emran Habibi, Mohammad Shokrzadeh, Aroona Chabra, Farshad Naghshvar, Razieh Keshavarz-Maleki & Amirhossein Ahmadi. (2015) Protective effects of Origanum vulgare ethanol extract against cyclophosphamide-induced liver toxicity in mice. Pharmaceutical Biology 53:1, pages 10-15.
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Arunabh Bhattacharya, Mizanur Rahman, Jameela Banu, Richard A. Lawrence, Howard S. McGuff, I.R. Garrett, Michael Fischbach & Gabriel Fernandes. (2005) Inhibition of Osteoporosis in Autoimmune Disease Prone MRL/Mpj-Faslpr Mice by N-3 Fatty Acids. Journal of the American College of Nutrition 24:3, pages 200-209.
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You Jung Kim, Takako Yokozawa & Hae Young Chung. (2005) Suppression of oxidative stress in aging NZB/NZW mice: Effect of fish oil feeding on hepatic antioxidant status and guanidino compounds. Free Radical Research 39:10, pages 1101-1110.
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W. Chen, J.P. Wang & Y.Q. Huang. (2012) Effects of dietary n-6:n-3 polyunsaturated fatty acid ratio on cardiac antioxidative status, T-cell and cytokine mRNA expression in the thymus, and blood T lymphocyte subsets of broilers. Livestock Science 150:1-3, pages 114-120.
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Mun-Ji Choi, Hyun-Kyung Kim & Myoung-Sook Lee. (2012) Vitamin E in vivo Studies on the Activity of Antioxidant Enzymes and CYP2E1 Expression in High PUFA-treated Brains. Journal of the Korean Society of Food Science and Nutrition 41:8, pages 1106-1111.
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Rosalia Crupi, Marco Cambiaghi, Richard Deckelbaum, Inge Hansen, Janet Mindes, Edoardo Spina & Fortunato Battaglia. (2012) n−3 fatty acids prevent impairment of neurogenesis and synaptic plasticity in B-cell activating factor (BAFF) transgenic mice. Preventive Medicine 54, pages S103-S108.
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Mei Li, Qin Zhu, Changwei Hu, John P. Giesy, Zhiming Kong & Yibin Cui. (2011) Protective effects of eicosapentaenoic acid on genotoxicity and oxidative stress of cyclophosphamide in mice. Environmental Toxicology 26:3, pages 217-223.
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Shams Tabrez & Masood Ahmad. (2011) Some enzymatic/nonenzymatic antioxidants as potential stress biomarkers of trichloroethylene, heavy metal mixture, and ethyl alcohol in rat tissues. Environmental Toxicology 26:2, pages 207-216.
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Orhan Veli Ozkan, Oktay Hasan Ozturk, Mehmet Aydin, Nigar Yilmaz, Ibrahim Yetim, Ahmet Nacar, Suleyman Oktar & Sadik Sogut. (2010) Effects of β-glucan pretreatment on acetylsalicylic acid-induced gastric damage: An experimental study in rats. Current Therapeutic Research 71:6, pages 369-383.
Crossref
James J. Pestka. (2010) n-3 Polyunsaturated fatty acids and autoimmune-mediated glomerulonephritis. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 82:4-6, pages 251-258.
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M. Umezawa, K. Higuchi, M. Mori, T. Matushita & M. Hosokawa. (2009) Effect of Dietary Unsaturated Fatty Acids on Senile Amyloidosis in Senescence-Accelerated Mice. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 64A:6, pages 646-652.
Crossref
Gregory W. Konat, Michal Kraszpulski, Isaac James, Han-Ting Zhang & Jame Abraham. (2008) Cognitive dysfunction induced by chronic administration of common cancer chemotherapeutics in rats. Metabolic Brain Disease 23:3, pages 325-333.
Crossref
D.N. Tripathi, A.A. Pawar, A. Vikram, P. Ramarao & G.B. Jena. (2008) Use of the alkaline comet assay for the detection of transplacental genotoxins in newborn mice. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 653:1-2, pages 134-139.
Crossref
Allain Amador Bueno, Lila Missae Oyama, Cristiane de Oliveira, Luciana Pelegrini Pisani, Eliane Beraldi Ribeiro, Vera Lucia Flor Silveira & Cláudia Maria Oller do Nascimento. (2007) Effects of different fatty acids and dietary lipids on adiponectin gene expression in 3T3-L1 cells and C57BL/6J mice adipose tissue. Pflügers Archiv - European Journal of Physiology 455:4, pages 701-709.
Crossref
Stuart Ware. 2007. Fatty Acids in Foods and their Health Implications,Third Edition. Fatty Acids in Foods and their Health Implications,Third Edition 1109 1144 .
Paolo Bergamo, Francesco Maurano & Mauro Rossi. (2007) Phase 2 enzyme induction by conjugated linoleic acid improves lupus-associated oxidative stress. Free Radical Biology and Medicine 43:1, pages 71-79.
Crossref
Arunabh Bhattacharya, Mizanur Rahman, Dongxu Sun & Gabriel Fernandes. (2007) Effect of fish oil on bone mineral density in aging C57BL/6 female mice. The Journal of Nutritional Biochemistry 18:6, pages 372-379.
Crossref
Arunabh Bhattacharya, Dongxu Sun, Mizanur Rahman & Gabriel Fernandes. (2007) Different ratios of eicosapentaenoic and docosahexaenoic omega-3 fatty acids in commercial fish oils differentially alter pro-inflammatory cytokines in peritoneal macrophages from C57BL/6 female mice. The Journal of Nutritional Biochemistry 18:1, pages 23-30.
Crossref
Paolo Bergamo, Diomira Luongo, Francesco Maurano, Giuseppe Mazzarella, Rosita Stefanile & Mauro Rossi. (2006) Conjugated linoleic acid enhances glutathione synthesis and attenuates pathological signs in MRL/MpJ-Faslpr mice. Journal of Lipid Research 47:11, pages 2382-2391.
Crossref
L. Kesavalu, B. Vasudevan, B. Raghu, E. Browning, D. Dawson, J. M. Novak, M.C. Correll, M.J. Steffen, A. Bhattacharya, G. Fernandes & J.L. Ebersole. (2016) Omega-3 Fatty Acid Effect on Alveolar Bone Loss in Rats. Journal of Dental Research 85:7, pages 648-652.
Crossref
You Jung Kim, Hyon Jeen Kim, Jae Kyung No, Hae Young Chung & Gabriel Fernandes. (2006) Anti-inflammatory action of dietary fish oil and calorie restriction. Life Sciences 78:21, pages 2523-2532.
Crossref
A. Bhattacharya, S. Ghosal & S.K. Bhattacharya. (2006) Effect of fish oil on offensive and defensive factors in gastric ulceration in rats. Prostaglandins, Leukotrienes and Essential Fatty Acids 74:2, pages 109-116.
Crossref
Christopher A. Jolly & Zhun Xu. 2006. Handbook of Models for Human Aging. Handbook of Models for Human Aging 771 779 .
Christopher A Jolly. (2005) Diet manipulation and prevention of aging, cancer and autoimmune disease. Current Opinion in Clinical Nutrition and Metabolic Care 8:4, pages 382-387.
Crossref
Elangovan Selvakumar, Chidambaram Prahalathan, Yenjerla Mythili & Palaninathan Varalakshmi. (2005) Mitigation of oxidative stress in cyclophosphamide-challenged hepatic tissue by DL-α-lipoic acid. Molecular and Cellular Biochemistry 272:1-2, pages 179-185.
Crossref
Dongxu Sun, Aparna Krishnan, Jianrong Su, Richard Lawrence, Khaliquz Zaman & Gabriel Fernandes. (2004) Regulation of immune function by calorie restriction and cyclophosphamide treatment in lupus-prone NZB/NZW F1 mice. Cellular Immunology 228:1, pages 54-65.
Crossref

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